BacMap

Definition	Escherichia coli 55989, complete genome.
Accession	NC_011748
Length	5,154,862

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The map label for this gene is ygfF

Identifier: 218696498

GI number: 218696498

Start: 3270278

End: 3271021

Strand: Reverse

Name: ygfF

Synonym: EC55989_3189

Alternate gene names: 218696498

Gene position: 3271021-3270278 (Counterclockwise)

Preceding gene: 218696499

Following gene: 218696496

Centisome position: 63.46

GC content: 55.11

Gene sequence:

>744_bases
ATGGCTATAGCACTTGTGACCGGTGGCAGTCGCGGCATCGGGCGGGCAACTGCATTACTGTTGGCGCAAGAAGGGTATAC
GGTGGCGGTTAATTATCAGCAAAACCTCCACGCGGCGCAGGAAGTGATGAACTTAATAACGCAAGCCGGTGGCAAAGCAT
TCGTGCTCCAGGCGGATATCAGCGACGAAAACCAGGTCGTTGCGATGTTTACAGCAATCGATCAGCACGATGAACCGCTA
GCAGCGCTGGTCAATAACGCCGGGATCTTGTTTACCCAGTGCACCGTTGAAAACCTTACCGCAGAGCGAATCAACCGAGT
ACTTTCCACCAACGTGACGGGATATTTTCTCTGCTGCCGCGAGGCGGTAAAACGCATGGCGCTTAAAAATGGTGGCAGTG
GCGGCGCTATCGTCAATGTCTCTTCGGTGGCCTCACGGTTGGGTTCGCCAGGGGAATATGTTGATTACGCGGCATCGAAA
GGGGCGATTGATACGTTAACCACCGGACTATCGCTGGAAGTCGCCGCGCAGGGGATCCGCGTTAACTGCGTGCGGCCAGG
GTTTATTTATACCGAAATGCACGCCAGCGGCGGCGAGCCTGGACGCGTCGATCGCGTTAAGTCGAACATCCCCATGCAGC
GTGGTGGACAGGCAGAAGAGGTCGCGCAGGCCATTGTCTGGCTACTAAGTGATAAAGCCTCTTACGTCACGGGAAGTTTT
ATCGATTTGGCGGGCGGGAAATAA

Upstream 100 bases:

>100_bases
GAAAGGGCGAGGGGGAAAAGCGTGCCAACATTGAAGATTGAGCCAGTTTGTTAGCAATCTCAAAGATACGTCAACGAATG
AATTTTTCTCGGAAAAACAA

Downstream 100 bases:

>100_bases
AACAGGGAAGTTGTCTGACCGGATGCAACAAGTATTGCATCCGGTACTTCATCGACTTAAAGCTTCTCGCCGTTGCTGGC
AATCACCTCTTTGTACCAGT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 247; Mature: 246

Protein sequence:

>247_residues
MAIALVTGGSRGIGRATALLLAQEGYTVAVNYQQNLHAAQEVMNLITQAGGKAFVLQADISDENQVVAMFTAIDQHDEPL
AALVNNAGILFTQCTVENLTAERINRVLSTNVTGYFLCCREAVKRMALKNGGSGGAIVNVSSVASRLGSPGEYVDYAASK
GAIDTLTTGLSLEVAAQGIRVNCVRPGFIYTEMHASGGEPGRVDRVKSNIPMQRGGQAEEVAQAIVWLLSDKASYVTGSF
IDLAGGK

Sequences:

>Translated_247_residues
MAIALVTGGSRGIGRATALLLAQEGYTVAVNYQQNLHAAQEVMNLITQAGGKAFVLQADISDENQVVAMFTAIDQHDEPL
AALVNNAGILFTQCTVENLTAERINRVLSTNVTGYFLCCREAVKRMALKNGGSGGAIVNVSSVASRLGSPGEYVDYAASK
GAIDTLTTGLSLEVAAQGIRVNCVRPGFIYTEMHASGGEPGRVDRVKSNIPMQRGGQAEEVAQAIVWLLSDKASYVTGSF
IDLAGGK
>Mature_246_residues
AIALVTGGSRGIGRATALLLAQEGYTVAVNYQQNLHAAQEVMNLITQAGGKAFVLQADISDENQVVAMFTAIDQHDEPLA
ALVNNAGILFTQCTVENLTAERINRVLSTNVTGYFLCCREAVKRMALKNGGSGGAIVNVSSVASRLGSPGEYVDYAASKG
AIDTLTTGLSLEVAAQGIRVNCVRPGFIYTEMHASGGEPGRVDRVKSNIPMQRGGQAEEVAQAIVWLLSDKASYVTGSFI
DLAGGK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family

Homologues:

Organism=Homo sapiens, GI40254992, Length=245, Percent_Identity=37.5510204081633, Blast_Score=135, Evalue=5e-32,
Organism=Homo sapiens, GI15277342, Length=254, Percent_Identity=33.8582677165354, Blast_Score=117, Evalue=7e-27,
Organism=Homo sapiens, GI19923817, Length=253, Percent_Identity=33.596837944664, Blast_Score=107, Evalue=7e-24,
Organism=Homo sapiens, GI32483357, Length=249, Percent_Identity=32.9317269076305, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI7705925, Length=244, Percent_Identity=31.5573770491803, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI109715829, Length=247, Percent_Identity=28.7449392712551, Blast_Score=81, Evalue=8e-16,
Organism=Homo sapiens, GI126723750, Length=251, Percent_Identity=29.4820717131474, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI5031737, Length=258, Percent_Identity=31.7829457364341, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI59889578, Length=201, Percent_Identity=28.8557213930348, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI31542939, Length=198, Percent_Identity=32.8282828282828, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI10190704, Length=251, Percent_Identity=28.2868525896414, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI66933014, Length=175, Percent_Identity=32, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI126723191, Length=186, Percent_Identity=33.3333333333333, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI4758504, Length=253, Percent_Identity=28.4584980237154, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI2367175, Length=247, Percent_Identity=100, Blast_Score=503, Evalue=1e-144,
Organism=Escherichia coli, GI1789378, Length=246, Percent_Identity=35.3658536585366, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1788459, Length=244, Percent_Identity=30.327868852459, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI1787335, Length=244, Percent_Identity=33.6065573770492, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1790717, Length=243, Percent_Identity=29.2181069958848, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI2367365, Length=243, Percent_Identity=32.5102880658436, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1786812, Length=254, Percent_Identity=31.8897637795276, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1789057, Length=257, Percent_Identity=29.9610894941634, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1787905, Length=243, Percent_Identity=30.4526748971193, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI87082160, Length=247, Percent_Identity=29.1497975708502, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI87082100, Length=247, Percent_Identity=29.1497975708502, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1789208, Length=245, Percent_Identity=27.7551020408163, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787526, Length=250, Percent_Identity=27.6, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787891, Length=244, Percent_Identity=26.2295081967213, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI25147288, Length=244, Percent_Identity=34.0163934426229, Blast_Score=113, Evalue=8e-26,
Organism=Caenorhabditis elegans, GI17555706, Length=248, Percent_Identity=34.2741935483871, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI71994604, Length=255, Percent_Identity=32.5490196078431, Blast_Score=112, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI115534694, Length=243, Percent_Identity=32.5102880658436, Blast_Score=107, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI71994600, Length=256, Percent_Identity=30.46875, Blast_Score=107, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI17559104, Length=268, Percent_Identity=30.5970149253731, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17536651, Length=250, Percent_Identity=32, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17536025, Length=254, Percent_Identity=31.8897637795276, Blast_Score=94, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17562910, Length=271, Percent_Identity=32.4723247232472, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17565030, Length=257, Percent_Identity=30.3501945525292, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17538480, Length=259, Percent_Identity=30.8880308880309, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17562906, Length=259, Percent_Identity=29.3436293436293, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI193204405, Length=260, Percent_Identity=30, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI72000259, Length=257, Percent_Identity=32.295719844358, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17538182, Length=259, Percent_Identity=31.2741312741313, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17531453, Length=260, Percent_Identity=31.5384615384615, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17538486, Length=266, Percent_Identity=27.8195488721804, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17563726, Length=261, Percent_Identity=30.6513409961686, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17560676, Length=254, Percent_Identity=31.496062992126, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17562904, Length=268, Percent_Identity=28.7313432835821, Blast_Score=81, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17544670, Length=262, Percent_Identity=28.2442748091603, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17560150, Length=262, Percent_Identity=29.3893129770992, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17551412, Length=267, Percent_Identity=31.0861423220974, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17561402, Length=252, Percent_Identity=30.1587301587302, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17561272, Length=246, Percent_Identity=26.8292682926829, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17562990, Length=262, Percent_Identity=30.1526717557252, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17560332, Length=265, Percent_Identity=30.188679245283, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17560220, Length=263, Percent_Identity=31.1787072243346, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17564282, Length=247, Percent_Identity=28.3400809716599, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17562908, Length=259, Percent_Identity=27.7992277992278, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17508895, Length=240, Percent_Identity=25.4166666666667, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI72001658, Length=220, Percent_Identity=29.5454545454545, Blast_Score=67, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6323882, Length=239, Percent_Identity=31.3807531380753, Blast_Score=81, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6324126, Length=249, Percent_Identity=26.5060240963855, Blast_Score=72, Evalue=8e-14,
Organism=Drosophila melanogaster, GI23397609, Length=257, Percent_Identity=36.9649805447471, Blast_Score=124, Evalue=8e-29,
Organism=Drosophila melanogaster, GI21357041, Length=255, Percent_Identity=36.4705882352941, Blast_Score=121, Evalue=4e-28,
Organism=Drosophila melanogaster, GI24644339, Length=256, Percent_Identity=35.15625, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI28571526, Length=254, Percent_Identity=34.251968503937, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24639444, Length=246, Percent_Identity=34.5528455284553, Blast_Score=113, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24643142, Length=245, Percent_Identity=33.8775510204082, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24644337, Length=214, Percent_Identity=32.7102803738318, Blast_Score=84, Evalue=8e-17,
Organism=Drosophila melanogaster, GI21355319, Length=253, Percent_Identity=30.4347826086957, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI17737361, Length=238, Percent_Identity=33.1932773109244, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24641232, Length=237, Percent_Identity=29.535864978903, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI116007236, Length=240, Percent_Identity=27.9166666666667, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24648944, Length=232, Percent_Identity=29.3103448275862, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI21356301, Length=187, Percent_Identity=30.4812834224599, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI281364892, Length=198, Percent_Identity=30.3030303030303, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24648693, Length=238, Percent_Identity=26.890756302521, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI21355889, Length=238, Percent_Identity=26.890756302521, Blast_Score=64, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YGFF_ECOLI (P52037)

Other databases:

- EMBL:   U28377
- EMBL:   U28375
- EMBL:   U00096
- EMBL:   AP009048
- EMBL:   D21144
- EMBL:   U83189
- PIR:   F65074
- RefSeq:   AP_003461.1
- RefSeq:   NP_417378.1
- ProteinModelPortal:   P52037
- SMR:   P52037
- DIP:   DIP-12165N
- IntAct:   P52037
- MINT:   MINT-1242731
- STRING:   P52037
- EnsemblBacteria:   EBESCT00000001953
- EnsemblBacteria:   EBESCT00000016893
- GeneID:   947373
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW2870
- KEGG:   eco:b2902
- EchoBASE:   EB2798
- EcoGene:   EG12971
- eggNOG:   COG1028
- GeneTree:   EBGT00050000009180
- HOGENOM:   HBG750976
- OMA:   RADISDE
- ProtClustDB:   PRK09730
- BioCyc:   EcoCyc:G7514-MONOMER
- Genevestigator:   P52037
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR19410
- PRINTS:   PR00081
- PRINTS:   PR00080

Pfam domain/function: PF00106 adh_short

EC number: 1.-.-.- [C]

Molecular weight: Translated: 25939; Mature: 25808

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: PS00061 ADH_SHORT

Important sites: ACT_SITE 156-156 BINDING 142-142

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIALVTGGSRGIGRATALLLAQEGYTVAVNYQQNLHAAQEVMNLITQAGGKAFVLQADI
CEEEEEECCCCCCCHHEEEEEEECCCEEEEECHHHHHHHHHHHHHHHHCCCCEEEEEECC
SDENQVVAMFTAIDQHDEPLAALVNNAGILFTQCTVENLTAERINRVLSTNVTGYFLCCR
CCCCCEEEEEEECCCCCCHHHHHHCCCCEEEEEEEHHHHHHHHHHHHHHCCCCHHHHHHH
EAVKRMALKNGGSGGAIVNVSSVASRLGSPGEYVDYAASKGAIDTLTTGLSLEVAAQGIR
HHHHHHHHHCCCCCCEEEEHHHHHHHHCCCCCHHHHHCCCCCHHHHHCCCEEEEEECCEE
VNCVRPGFIYTEMHASGGEPGRVDRVKSNIPMQRGGQAEEVAQAIVWLLSDKASYVTGSF
EEEECCCEEEEEEECCCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCE
IDLAGGK
EECCCCC
>Mature Secondary Structure 
AIALVTGGSRGIGRATALLLAQEGYTVAVNYQQNLHAAQEVMNLITQAGGKAFVLQADI
EEEEEECCCCCCCHHEEEEEEECCCEEEEECHHHHHHHHHHHHHHHHCCCCEEEEEECC
SDENQVVAMFTAIDQHDEPLAALVNNAGILFTQCTVENLTAERINRVLSTNVTGYFLCCR
CCCCCEEEEEEECCCCCCHHHHHHCCCCEEEEEEEHHHHHHHHHHHHHHCCCCHHHHHHH
EAVKRMALKNGGSGGAIVNVSSVASRLGSPGEYVDYAASKGAIDTLTTGLSLEVAAQGIR
HHHHHHHHHCCCCCCEEEEHHHHHHHHCCCCCHHHHHCCCCCHHHHHCCCEEEEEECCEE
VNCVRPGFIYTEMHASGGEPGRVDRVKSNIPMQRGGQAEEVAQAIVWLLSDKASYVTGSF
EEEECCCEEEEEEECCCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCE
IDLAGGK
EECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503; 7764507