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The map label for this gene is ydjQ

Identifier: 218695299

GI number: 218695299

Start: 1971947

End: 1972834

Strand: Direct

Name: ydjQ

Synonym: EC55989_1909

Alternate gene names: 218695299

Gene position: 1971947-1972834 (Clockwise)

Preceding gene: 218695298

Following gene: 218695307

Centisome position: 38.25

GC content: 51.35

Gene sequence:

>888_bases
GTGGTACGGCGTTTAACTTCTCCGCGGCTCGAATTTGAAGCTGCGGCAATTTATGAATATCCCGAACATTTACGTTCATT
CCTTAATGACTTACCCACCCGACCAGGGGTGTATCTGTTTCATGGCGAAAGTGACACCATGCCGCTCTATATCGGCAAAA
GCGTTAATATCCGCAGTCGGGTGCTTTCTCATTTACGCACCCCGGATGAAGCCGCCATGCTACGGCAATCCCGGCGAATT
AGCTGGATCTGCACCGCAGGCGAAATCGGCGCTCTGCTCCTTGAAGCGCGATTAATCAAAGAACAACAGCCGCTGTTTAA
TAAACGGTTGCGCCGCAATCGCCAGCTCTGTGCCCTGCAATTAAATGAAAAGCGCGTCGATGTGGTGTATGCCAAAGAGG
TGGATTTTTCACGAGCCCCCAACCTGTTTGGCCTGTTTGCCAATAGGCGCGCAGCTTTGCAAGCATTGCAGAGCATCGCT
GATGAACAAAAACTTTGTTATGGCCTGTTGGGACTGGAACCGTTAAGTCGCGGTCGTGCATGTTTTCGTTCAGCGCTAAA
ACGTTGCGCCGGAGCATGCTGCGGTAAAGAGAGCCATGAGGAACATGCGCTACGCTTGCGCCAGTCTCTGGAGCGTTTGC
GGGTGGTGTGTTGGCCTTGGCAAGGTGCGGTGGCACTGAAAGAACAGCACCCGGAAATGACTCAATATCATATTATTCAA
AACTGGCTGTGGCTGGGGGCGGTTAATTCGCTGGAAGAAGCGACAACGTTAATTCGGACACCCGCCGGGTTTGATCACGA
CGGTTATAAAATTCTTTGTAAGCCGCTGCTTTCCGGTAACTATGAAATTACTGAACTTGATCCGGCGAATGACCAGCGAG
CCAGTTGA

Upstream 100 bases:

>100_bases
GTAGCACGTCAGACGGTGTAACCTTTGTCATCAACCCGCCTCTTTTTTAATCGCCTCCCGCCTGTTACACTGGATAGATA
ACCAGCATTCGGAGTCAACA

Downstream 100 bases:

>100_bases
TTTCACTGAACAACAGTTTACCTTGCGGTTGTAAAAGCCGCAGGGTGTGCCTGCCATCGAACCAGCACGCGCCCTGGTCG
GTAGTGAGCAATTTATCGCC

Product: nucleotide excision repair endonuclease

Products: NA

Alternate protein names: Endonuclease cho; UvrC homolog protein

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MVRRLTSPRLEFEAAAIYEYPEHLRSFLNDLPTRPGVYLFHGESDTMPLYIGKSVNIRSRVLSHLRTPDEAAMLRQSRRI
SWICTAGEIGALLLEARLIKEQQPLFNKRLRRNRQLCALQLNEKRVDVVYAKEVDFSRAPNLFGLFANRRAALQALQSIA
DEQKLCYGLLGLEPLSRGRACFRSALKRCAGACCGKESHEEHALRLRQSLERLRVVCWPWQGAVALKEQHPEMTQYHIIQ
NWLWLGAVNSLEEATTLIRTPAGFDHDGYKILCKPLLSGNYEITELDPANDQRAS

Sequences:

>Translated_295_residues
MVRRLTSPRLEFEAAAIYEYPEHLRSFLNDLPTRPGVYLFHGESDTMPLYIGKSVNIRSRVLSHLRTPDEAAMLRQSRRI
SWICTAGEIGALLLEARLIKEQQPLFNKRLRRNRQLCALQLNEKRVDVVYAKEVDFSRAPNLFGLFANRRAALQALQSIA
DEQKLCYGLLGLEPLSRGRACFRSALKRCAGACCGKESHEEHALRLRQSLERLRVVCWPWQGAVALKEQHPEMTQYHIIQ
NWLWLGAVNSLEEATTLIRTPAGFDHDGYKILCKPLLSGNYEITELDPANDQRAS
>Mature_295_residues
MVRRLTSPRLEFEAAAIYEYPEHLRSFLNDLPTRPGVYLFHGESDTMPLYIGKSVNIRSRVLSHLRTPDEAAMLRQSRRI
SWICTAGEIGALLLEARLIKEQQPLFNKRLRRNRQLCALQLNEKRVDVVYAKEVDFSRAPNLFGLFANRRAALQALQSIA
DEQKLCYGLLGLEPLSRGRACFRSALKRCAGACCGKESHEEHALRLRQSLERLRVVCWPWQGAVALKEQHPEMTQYHIIQ
NWLWLGAVNSLEEATTLIRTPAGFDHDGYKILCKPLLSGNYEITELDPANDQRAS

Specific function: Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than uvrC. Not able to incise the 5' site of a lesion. When a lesion remains because uvrC is not able to induce the 3' incision, cho

COG id: COG0322

COG function: function code L; Nuclease subunit of the excinuclease complex

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 uvrC C-terminal domain

Homologues:

Organism=Escherichia coli, GI1788037, Length=295, Percent_Identity=99.6610169491526, Blast_Score=607, Evalue=1e-175,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CHO_ECO57 (Q8XDZ7)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   C85783
- PIR:   G90934
- RefSeq:   NP_288174.1
- RefSeq:   NP_310474.1
- ProteinModelPortal:   Q8XDZ7
- SMR:   Q8XDZ7
- EnsemblBacteria:   EBESCT00000026893
- EnsemblBacteria:   EBESCT00000058035
- GeneID:   912511
- GeneID:   961711
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z2771
- KEGG:   ecs:ECs2447
- GeneTree:   EBGT00050000011759
- HOGENOM:   HBG336547
- OMA:   RQSRRIT
- ProtClustDB:   PRK10545
- BioCyc:   ECOL83334:ECS2447-MONOMER
- GO:   GO:0005622
- InterPro:   IPR000305
- SMART:   SM00465

Pfam domain/function: PF01541 GIY-YIG; SSF82771 UvrC_N

EC number: NA

Molecular weight: Translated: 33725; Mature: 33725

Theoretical pI: Translated: 8.94; Mature: 8.94

Prosite motif: PS50164 UVRC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRRLTSPRLEFEAAAIYEYPEHLRSFLNDLPTRPGVYLFHGESDTMPLYIGKSVNIRSR
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEEECCCCCHHHH
VLSHLRTPDEAAMLRQSRRISWICTAGEIGALLLEARLIKEQQPLFNKRLRRNRQLCALQ
HHHHHCCCHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHCCHHHHHHHHCCCCEEEEE
LNEKRVDVVYAKEVDFSRAPNLFGLFANRRAALQALQSIADEQKLCYGLLGLEPLSRGRA
ECCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
CFRSALKRCAGACCGKESHEEHALRLRQSLERLRVVCWPWQGAVALKEQHPEMTQYHIIQ
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHEEEEECCCCCCHHHHCCCCHHHHHHHH
NWLWLGAVNSLEEATTLIRTPAGFDHDGYKILCKPLLSGNYEITELDPANDQRAS
HHHHHHHHHHHHHHHHHHCCCCCCCCCCHHEEEEHHHCCCEEEEEECCCCCCCCC
>Mature Secondary Structure
MVRRLTSPRLEFEAAAIYEYPEHLRSFLNDLPTRPGVYLFHGESDTMPLYIGKSVNIRSR
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEEECCCCCHHHH
VLSHLRTPDEAAMLRQSRRISWICTAGEIGALLLEARLIKEQQPLFNKRLRRNRQLCALQ
HHHHHCCCHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHCCHHHHHHHHCCCCEEEEE
LNEKRVDVVYAKEVDFSRAPNLFGLFANRRAALQALQSIADEQKLCYGLLGLEPLSRGRA
ECCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
CFRSALKRCAGACCGKESHEEHALRLRQSLERLRVVCWPWQGAVALKEQHPEMTQYHIIQ
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHEEEEECCCCCCHHHHCCCCHHHHHHHH
NWLWLGAVNSLEEATTLIRTPAGFDHDGYKILCKPLLSGNYEITELDPANDQRAS
HHHHHHHHHHHHHHHHHHCCCCCCCCCCHHEEEEHHHCCCEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796