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The map label for this gene is chbC [H]

Identifier: 218695073

GI number: 218695073

Start: 1739926

End: 1741287

Strand: Reverse

Name: chbC [H]

Synonym: EC55989_1671

Alternate gene names: 218695073

Gene position: 1741287-1739926 (Counterclockwise)

Preceding gene: 218695074

Following gene: 218695072

Centisome position: 33.78

GC content: 42.29

Gene sequence:

>1362_bases
TTGGGATGTATAAATATCCAAAACAACAGGTATAAAAAAATGGGATTAATGGCCTCATTCGAACGTGGAATGGAACGTTT
TCTTGTTCCAGTTGCTATCAAGTTAAACTCACAAAAACATGTTGCAGCGGTGAGAGATGGATTCGTTTTTACGTTTCCAA
TTATCATGGCAAGTTCATTAATTATATTAATTAACTTTGCCATATTATCGCCAGACGGTTTTATTGCCGGATTACTGCAT
CTGAATAGCATTTTCCCCAACCTTGAAAAAGCACAAGCTATTTTTACTCCGGTAATGAATGGTTCTGTAAATATCATGTC
AATTATGATTGCTTTCCTGGTCGCCAGGAATATGGCGATTAGCTATGAGCAAGATGATCTTTTATGCGGATTAACGGCAA
TAGGAGCATTTTTTATTGTTTATACGCCATATCAGATGATAGATGGGCAAGCATTCCTGACGACCAAATATCTCGGCGCG
CAGGGGTTGTTTGTTGCTGTTATCGTTGCATTGATCACCAGTGAAATATTTTGTCGCTTAGCTCGAAACCCAAAAATCAC
CATAACGATGCCGGCAGCTGTACCGCCTGCGGTAGCGCGTTCATTTAAAGTTTTATTGCCAATATTTTTTGTCATGGTGT
TCTTTTCCGCACTTAATTATTGCCTGACACTGATATCCCCGGCAGGACTAAACGATCTTATTTACACATTAATCCAGACG
CCGCTCAAACATATGGGAACGAATATCTTTGCGGTAATTATCCTGGGGGCTGTGGGTAATTTCCTGTGGGTGCTGGGGAT
CCACGGACCTAATACCACATCGGCAATTCGAGAAACCGTTTTTTCTGAGGCTAATCTGGAGAATCTCTCCTGGGCCGCTC
AACATGGCACTACCTGGGGCGCGCCATATCCGATTACCTGGACTTCTATTAATGATGCATTTGCCAACTGCGGCGGTTCA
GGTATGACGTTGGGGTTATTGTTGGCTATTTTTATCGCTTCTAAGCGTGCGGAATACCGTGATCTGGCAAAAATGTCATT
TATCCCCGGTATTTTCAATATCAATGAACCGATAATGTTTGGCCTTCCTATTGTACTTAACCCCATCATGATGGTGCCGT
TTATTATGGTTCCCATTGTTAACTGTGCCATTGGTTACTTCTTTATTTCGATGGAAATTATTCCACCGGTTGCTTATGCC
GTGCCCTGGACTACGCCCGGACCTTTAATTGCTTTCCTCGGAACCGGGGGGAACTGGCTGGCTTTACTGGTTGGTTTTTT
ATGTTTAGGTGTGGCGACAATGATCTATTTACCTTTTGTTATTGCCGCCAACAAAGTCAATAACATGACAACTAACGGAT
AA

Upstream 100 bases:

>100_bases
TGCGATGAAACTACTGCAAGAGTAAGAATCTAATATTATTAAACTATTACCTGAACTAACTTTTCACACATCATAAAATG
GATATGGCATACATGCTTTA

Downstream 100 bases:

>100_bases
TTCCATTTACCCAGGAAGGAGATTGTGATGTTTGCAGATGAAGAACTTGTTATGGAGTTACTGGTCAACGCGGGGCAGGC
ACGTTCTGACGCGATGGAAG

Product: putative phosphotransferase system IIC component

Products: pyruvate; diacetylchitobiose-6-phosphate [Cytoplasm]; cellobiose-6-phosphate [Cytoplasm] [C]

Alternate protein names: EIIC-Chb; PTS system N,N'-diacetylchitobiose-specific EIIC component [H]

Number of amino acids: Translated: 453; Mature: 452

Protein sequence:

>453_residues
MGCINIQNNRYKKMGLMASFERGMERFLVPVAIKLNSQKHVAAVRDGFVFTFPIIMASSLIILINFAILSPDGFIAGLLH
LNSIFPNLEKAQAIFTPVMNGSVNIMSIMIAFLVARNMAISYEQDDLLCGLTAIGAFFIVYTPYQMIDGQAFLTTKYLGA
QGLFVAVIVALITSEIFCRLARNPKITITMPAAVPPAVARSFKVLLPIFFVMVFFSALNYCLTLISPAGLNDLIYTLIQT
PLKHMGTNIFAVIILGAVGNFLWVLGIHGPNTTSAIRETVFSEANLENLSWAAQHGTTWGAPYPITWTSINDAFANCGGS
GMTLGLLLAIFIASKRAEYRDLAKMSFIPGIFNINEPIMFGLPIVLNPIMMVPFIMVPIVNCAIGYFFISMEIIPPVAYA
VPWTTPGPLIAFLGTGGNWLALLVGFLCLGVATMIYLPFVIAANKVNNMTTNG

Sequences:

>Translated_453_residues
MGCINIQNNRYKKMGLMASFERGMERFLVPVAIKLNSQKHVAAVRDGFVFTFPIIMASSLIILINFAILSPDGFIAGLLH
LNSIFPNLEKAQAIFTPVMNGSVNIMSIMIAFLVARNMAISYEQDDLLCGLTAIGAFFIVYTPYQMIDGQAFLTTKYLGA
QGLFVAVIVALITSEIFCRLARNPKITITMPAAVPPAVARSFKVLLPIFFVMVFFSALNYCLTLISPAGLNDLIYTLIQT
PLKHMGTNIFAVIILGAVGNFLWVLGIHGPNTTSAIRETVFSEANLENLSWAAQHGTTWGAPYPITWTSINDAFANCGGS
GMTLGLLLAIFIASKRAEYRDLAKMSFIPGIFNINEPIMFGLPIVLNPIMMVPFIMVPIVNCAIGYFFISMEIIPPVAYA
VPWTTPGPLIAFLGTGGNWLALLVGFLCLGVATMIYLPFVIAANKVNNMTTNG
>Mature_452_residues
GCINIQNNRYKKMGLMASFERGMERFLVPVAIKLNSQKHVAAVRDGFVFTFPIIMASSLIILINFAILSPDGFIAGLLHL
NSIFPNLEKAQAIFTPVMNGSVNIMSIMIAFLVARNMAISYEQDDLLCGLTAIGAFFIVYTPYQMIDGQAFLTTKYLGAQ
GLFVAVIVALITSEIFCRLARNPKITITMPAAVPPAVARSFKVLLPIFFVMVFFSALNYCLTLISPAGLNDLIYTLIQTP
LKHMGTNIFAVIILGAVGNFLWVLGIHGPNTTSAIRETVFSEANLENLSWAAQHGTTWGAPYPITWTSINDAFANCGGSG
MTLGLLLAIFIASKRAEYRDLAKMSFIPGIFNINEPIMFGLPIVLNPIMMVPFIMVPIVNCAIGYFFISMEIIPPVAYAV
PWTTPGPLIAFLGTGGNWLALLVGFLCLGVATMIYLPFVIAANKVNNMTTNG

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-3 domain [H]

Homologues:

Organism=Escherichia coli, GI1788032, Length=443, Percent_Identity=36.7945823927765, Blast_Score=254, Evalue=8e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003352
- InterPro:   IPR004796
- InterPro:   IPR004501 [H]

Pfam domain/function: PF02378 PTS_EIIC [H]

EC number: NA

Molecular weight: Translated: 49328; Mature: 49196

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: PS51105 PTS_EIIC_TYPE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGCINIQNNRYKKMGLMASFERGMERFLVPVAIKLNSQKHVAAVRDGFVFTFPIIMASSL
CCCEECCCCCHHHHHHHHHHHHHHHHHEEEEEEEECCCHHHHHHHCCCHHEEHHHHHHHH
IILINFAILSPDGFIAGLLHLNSIFPNLEKAQAIFTPVMNGSVNIMSIMIAFLVARNMAI
HHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCEE
SYEQDDLLCGLTAIGAFFIVYTPYQMIDGQAFLTTKYLGAQGLFVAVIVALITSEIFCRL
EECCCHHHHHHHHHHHHHHHCCCHHHHCCCEEEEEHHHCCCHHHHHHHHHHHHHHHHHHH
ARNPKITITMPAAVPPAVARSFKVLLPIFFVMVFFSALNYCLTLISPAGLNDLIYTLIQT
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
PLKHMGTNIFAVIILGAVGNFLWVLGIHGPNTTSAIRETVFSEANLENLSWAAQHGTTWG
HHHHHCCHHHHHHHHHHHHCEEEEEEECCCCHHHHHHHHHHHCCCCCCCHHHHHCCCCCC
APYPITWTSINDAFANCGGSGMTLGLLLAIFIASKRAEYRDLAKMSFIPGIFNINEPIMF
CCCCEEECCCCHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCHHC
GLPIVLNPIMMVPFIMVPIVNCAIGYFFISMEIIPPVAYAVPWTTPGPLIAFLGTGGNWL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEECCCCCCCCEEEEEECCCCHH
ALLVGFLCLGVATMIYLPFVIAANKVNNMTTNG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
GCINIQNNRYKKMGLMASFERGMERFLVPVAIKLNSQKHVAAVRDGFVFTFPIIMASSL
CCEECCCCCHHHHHHHHHHHHHHHHHEEEEEEEECCCHHHHHHHCCCHHEEHHHHHHHH
IILINFAILSPDGFIAGLLHLNSIFPNLEKAQAIFTPVMNGSVNIMSIMIAFLVARNMAI
HHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCEE
SYEQDDLLCGLTAIGAFFIVYTPYQMIDGQAFLTTKYLGAQGLFVAVIVALITSEIFCRL
EECCCHHHHHHHHHHHHHHHCCCHHHHCCCEEEEEHHHCCCHHHHHHHHHHHHHHHHHHH
ARNPKITITMPAAVPPAVARSFKVLLPIFFVMVFFSALNYCLTLISPAGLNDLIYTLIQT
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
PLKHMGTNIFAVIILGAVGNFLWVLGIHGPNTTSAIRETVFSEANLENLSWAAQHGTTWG
HHHHHCCHHHHHHHHHHHHCEEEEEEECCCCHHHHHHHHHHHCCCCCCCHHHHHCCCCCC
APYPITWTSINDAFANCGGSGMTLGLLLAIFIASKRAEYRDLAKMSFIPGIFNINEPIMF
CCCCEEECCCCHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCHHC
GLPIVLNPIMMVPFIMVPIVNCAIGYFFISMEIIPPVAYAVPWTTPGPLIAFLGTGGNWL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEECCCCCCCCEEEEEECCCCHH
ALLVGFLCLGVATMIYLPFVIAANKVNNMTTNG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: diacetylchitobiose [Periplasm]; phosphoenolpyruvate; cellobiose [Periplasm] [C]

Specific reaction: phosphoenolpyruvate + diacetylchitobiose [Periplasm] = pyruvate + diacetylchitobiose-6-phosphate [Cytoplasm] phosphoenolpyruvate + cellobiose [Periplasm] = cellobiose-6-phosphate [Cytoplasm] + pyruvate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2179047; 9097039; 9278503; 2092358; 9405618; 10913117 [H]