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The map label for this gene is ydcR

Identifier: 218694980

GI number: 218694980

Start: 1618511

End: 1619917

Strand: Direct

Name: ydcR

Synonym: EC55989_1571

Alternate gene names: 218694980

Gene position: 1618511-1619917 (Clockwise)

Preceding gene: 218694979

Following gene: 218694981

Centisome position: 31.4

GC content: 51.31

Gene sequence:

>1407_bases
ATGAAAAAATACCAGCAGCTTGCAGAACAATTACGCGAGCAGATTGCGTCGGGTATCTGGCAACCCGGCGATCGTTTGCC
TTCGTTGCGTGACCAGGTGGCGCTTTCAGGCATGAGCTTTATGACTGTCAGCCATGCCTATCAGTTGCTCGAAAGTCAGG
GATATATTATCGCACGACCGCAGTCGGGTTATTACGTTGCGCCACAGGCAATAAAAATGCCGAAAGCGCCAGTCATTCCA
GTCACTCGAGATGAAGCAGTCGATATCAACACTTATATTTTTGATATGTTGCAGGCCAGTCGCGATCCGTCGGTCGTTCC
GTTTGCCTCGGCCTTTCCCGACCCGCGACTTTTCCCCCTCCAACAACTAAACCGCTCGCTGGCGCAGGTAAGCAAAACCG
CCACAGCGATGAGCGTGATTGAAAACTTACCGCCAGGAAACGCAGAACTGCGTCAGGCTATTGCTCGTCGCTATGCCTTA
CAGGGCATCACCATTTCTCCTGATGAAATTGTCATTACTGCCGGGGCGTTAGAGGCATTAAACCTCAGTTTGCAAGCGGT
AACTGAACCGGGCGATTGGGTGATAGTAGAGAATCCTTGTTTCTACGGTGCGTTGCAGGCGCTGGAGCGGCTACGGCTGA
AGGCGTTATCGGTGGCGACGGATGTTAAAGAAGGGATCGATCTTCAGGCGCTGGAACTGGCGTTGCAGGATTATCCGGTG
AAAGCGTGCTGGCTGATGACTAATAGCCAGAACCCACTCGGATTTACCTTAACGCCGCAAAAAAAAGCACAACTGGTGGC
GTTACTCAATCAGTACAACGTAACGCTGATTGAAGATGACGTTTACAGCGAACTTTATTTTGGACGGGAAAAACCGCTGC
CTGCGAAAGCGTGGGATCGCCACGATGGCGTTTTGCATTGCTCTTCGTTTTCGAAATGTCTGGTGCCTGGTTTTCGTATT
GGTTGGGTCGCCGCCGGAAAACATGCACGTAAAATTCAACGCTTGCAGTTGATGAGTACGCTTTCCACCAGCTCACCGAT
GCAACTTGCGCTGGTGGATTACCTTTCCACGCGCCGATACGACGCCCATCTTCGTCGCCTGCGTCGCCAGCTTGCGGAAC
GTAAACAACGTGCCTGGCAGGCACTGCTGCGTTATCTGCCTGCGGAAGTTAAAATTCATCATAGTGACAGCGGTTATTTT
CTCTGGCTGGAGCTCCCCGAGCCGTTAGATGCCGGCGAATTAAGCCTGGCGGCACTGACGCATCATATCAGTATTGCGCC
GGGTAAAATGTTTTCTACCGGTGAAAACTGGTCACGTTTTTTTCGTTTTAATACCGCGTGGCAGTGGGGAGAACGTGAAG
AACAGGCGGTAAAACAATTAGGCAAACTTATTCAAGAACGGCTGTAA

Upstream 100 bases:

>100_bases
GTTATCGCTGGTGATGGTTTAATTACAGTTAACGAAAAGTTGTCATTTTTAACAACTGATATAGACTGCCGAATCATCTG
CACATAATTACGATTCGATA

Downstream 100 bases:

>100_bases
TAGCGTTTAATTTAATTCCTCTTAGATTGGGTAATATGAATTTCGAATAGCAGTCATATTTCCTAACCCCTTGTCTATAC
TCCAGAAGATAACCTTACAG

Product: putative DNA-binding transcriptional regulator fused with a domain with PLP-binding motif

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 468; Mature: 468

Protein sequence:

>468_residues
MKKYQQLAEQLREQIASGIWQPGDRLPSLRDQVALSGMSFMTVSHAYQLLESQGYIIARPQSGYYVAPQAIKMPKAPVIP
VTRDEAVDINTYIFDMLQASRDPSVVPFASAFPDPRLFPLQQLNRSLAQVSKTATAMSVIENLPPGNAELRQAIARRYAL
QGITISPDEIVITAGALEALNLSLQAVTEPGDWVIVENPCFYGALQALERLRLKALSVATDVKEGIDLQALELALQDYPV
KACWLMTNSQNPLGFTLTPQKKAQLVALLNQYNVTLIEDDVYSELYFGREKPLPAKAWDRHDGVLHCSSFSKCLVPGFRI
GWVAAGKHARKIQRLQLMSTLSTSSPMQLALVDYLSTRRYDAHLRRLRRQLAERKQRAWQALLRYLPAEVKIHHSDSGYF
LWLELPEPLDAGELSLAALTHHISIAPGKMFSTGENWSRFFRFNTAWQWGEREEQAVKQLGKLIQERL

Sequences:

>Translated_468_residues
MKKYQQLAEQLREQIASGIWQPGDRLPSLRDQVALSGMSFMTVSHAYQLLESQGYIIARPQSGYYVAPQAIKMPKAPVIP
VTRDEAVDINTYIFDMLQASRDPSVVPFASAFPDPRLFPLQQLNRSLAQVSKTATAMSVIENLPPGNAELRQAIARRYAL
QGITISPDEIVITAGALEALNLSLQAVTEPGDWVIVENPCFYGALQALERLRLKALSVATDVKEGIDLQALELALQDYPV
KACWLMTNSQNPLGFTLTPQKKAQLVALLNQYNVTLIEDDVYSELYFGREKPLPAKAWDRHDGVLHCSSFSKCLVPGFRI
GWVAAGKHARKIQRLQLMSTLSTSSPMQLALVDYLSTRRYDAHLRRLRRQLAERKQRAWQALLRYLPAEVKIHHSDSGYF
LWLELPEPLDAGELSLAALTHHISIAPGKMFSTGENWSRFFRFNTAWQWGEREEQAVKQLGKLIQERL
>Mature_468_residues
MKKYQQLAEQLREQIASGIWQPGDRLPSLRDQVALSGMSFMTVSHAYQLLESQGYIIARPQSGYYVAPQAIKMPKAPVIP
VTRDEAVDINTYIFDMLQASRDPSVVPFASAFPDPRLFPLQQLNRSLAQVSKTATAMSVIENLPPGNAELRQAIARRYAL
QGITISPDEIVITAGALEALNLSLQAVTEPGDWVIVENPCFYGALQALERLRLKALSVATDVKEGIDLQALELALQDYPV
KACWLMTNSQNPLGFTLTPQKKAQLVALLNQYNVTLIEDDVYSELYFGREKPLPAKAWDRHDGVLHCSSFSKCLVPGFRI
GWVAAGKHARKIQRLQLMSTLSTSSPMQLALVDYLSTRRYDAHLRRLRRQLAERKQRAWQALLRYLPAEVKIHHSDSGYF
LWLELPEPLDAGELSLAALTHHISIAPGKMFSTGENWSRFFRFNTAWQWGEREEQAVKQLGKLIQERL

Specific function: Unknown

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=401, Percent_Identity=25.6857855361596, Blast_Score=103, Evalue=5e-22,
Organism=Homo sapiens, GI33469970, Length=401, Percent_Identity=25.6857855361596, Blast_Score=103, Evalue=5e-22,
Organism=Homo sapiens, GI4507369, Length=236, Percent_Identity=23.728813559322, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI56713256, Length=399, Percent_Identity=24.0601503759398, Blast_Score=73, Evalue=7e-13,
Organism=Homo sapiens, GI56713254, Length=399, Percent_Identity=24.0601503759398, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1787710, Length=468, Percent_Identity=99.5726495726496, Blast_Score=959, Evalue=0.0,
Organism=Escherichia coli, GI1790797, Length=466, Percent_Identity=34.9785407725322, Blast_Score=299, Evalue=2e-82,
Organism=Escherichia coli, GI1788722, Length=312, Percent_Identity=25.9615384615385, Blast_Score=75, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17567663, Length=184, Percent_Identity=26.6304347826087, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI21356535, Length=331, Percent_Identity=24.4712990936556, Blast_Score=88, Evalue=2e-17,
Organism=Drosophila melanogaster, GI18859735, Length=224, Percent_Identity=27.6785714285714, Blast_Score=69, Evalue=8e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 52752; Mature: 52752

Theoretical pI: Translated: 8.96; Mature: 8.96

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKYQQLAEQLREQIASGIWQPGDRLPSLRDQVALSGMSFMTVSHAYQLLESQGYIIARP
CCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEECC
QSGYYVAPQAIKMPKAPVIPVTRDEAVDINTYIFDMLQASRDPSVVPFASAFPDPRLFPL
CCCEEECCHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEHHCCCCCCCCCH
QQLNRSLAQVSKTATAMSVIENLPPGNAELRQAIARRYALQGITISPDEIVITAGALEAL
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEECCCCEEEEECCHHHH
NLSLQAVTEPGDWVIVENPCFYGALQALERLRLKALSVATDVKEGIDLQALELALQDYPV
CCEEEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCC
KACWLMTNSQNPLGFTLTPQKKAQLVALLNQYNVTLIEDDVYSELYFGREKPLPAKAWDR
EEEEEEECCCCCCEEEECCHHHHHHHHHHHHCCEEEEECHHHHHHHCCCCCCCCCCCCCC
HDGVLHCSSFSKCLVPGFRIGWVAAGKHARKIQRLQLMSTLSTSSPMQLALVDYLSTRRY
CCCEEEECCCCHHHCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
DAHLRRLRRQLAERKQRAWQALLRYLPAEVKIHHSDSGYFLWLELPEPLDAGELSLAALT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEEEECCCCCCCCCHHHHHHH
HHISIAPGKMFSTGENWSRFFRFNTAWQWGEREEQAVKQLGKLIQERL
HHEEECCCCCCCCCCCHHHHEEECCCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKYQQLAEQLREQIASGIWQPGDRLPSLRDQVALSGMSFMTVSHAYQLLESQGYIIARP
CCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEECC
QSGYYVAPQAIKMPKAPVIPVTRDEAVDINTYIFDMLQASRDPSVVPFASAFPDPRLFPL
CCCEEECCHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEHHCCCCCCCCCH
QQLNRSLAQVSKTATAMSVIENLPPGNAELRQAIARRYALQGITISPDEIVITAGALEAL
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEECCCCEEEEECCHHHH
NLSLQAVTEPGDWVIVENPCFYGALQALERLRLKALSVATDVKEGIDLQALELALQDYPV
CCEEEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCC
KACWLMTNSQNPLGFTLTPQKKAQLVALLNQYNVTLIEDDVYSELYFGREKPLPAKAWDR
EEEEEEECCCCCCEEEECCHHHHHHHHHHHHCCEEEEECHHHHHHHCCCCCCCCCCCCCC
HDGVLHCSSFSKCLVPGFRIGWVAAGKHARKIQRLQLMSTLSTSSPMQLALVDYLSTRRY
CCCEEEECCCCHHHCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
DAHLRRLRRQLAERKQRAWQALLRYLPAEVKIHHSDSGYFLWLELPEPLDAGELSLAALT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEEEECCCCCCCCCHHHHHHH
HHISIAPGKMFSTGENWSRFFRFNTAWQWGEREEQAVKQLGKLIQERL
HHEEECCCCCCCCCCCHHHHEEECCCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]