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The map label for this gene is ymdC

Identifier: 218694580

GI number: 218694580

Start: 1216492

End: 1217913

Strand: Direct

Name: ymdC

Synonym: EC55989_1159

Alternate gene names: 218694580

Gene position: 1216492-1217913 (Clockwise)

Preceding gene: 218694579

Following gene: 218694584

Centisome position: 23.6

GC content: 50.91

Gene sequence:

>1422_bases
TTGCCCCGGCTGGCGAGCGCGGTGCTGCCACTGTGTTCGCAACATCCCGGTCAGTGTGGTCTTTTCCCTCTGGAGAAAAG
TCTGGATGCGTTTGCCGCCCGGTATCGTCTGGCCGAAATGGCAGAGCATACGCTGGATGTTCAGTATTACATCTGGCAGG
ACGATATGTCGGGTCGGTTACTGTTTTCCGCCCTGTTAGCCGCAGCAAAGCGTGGCGTTCGCGTCCGTTTGTTGCTGGAC
GACAACAATACGCCCGGACTTGACGACATTTTACGCTTGCTTGACAGCCATCCCCGCATTGAAGTCCGGCTTTTTAATCC
TTTCTCGTTTCGCTTGCTGCGTCCGCTTGGTTATATCACCGACTTTTCCCGTCTCAATCGCCGTATGCACAATAAAAGTT
TCACTGTCGATGGCGTGGTGACGCTGGTAGGGGGGCGAAATATTGGTGATGCCTATTTTGGGGCAGGGGAAGAGCCACTT
TTTTCGGATTTAGATGTTATGGCAATAGGGCCCGTGGTAGAGGACGTTGCCGATGATTTCGCCCGCTACTGGTATTGCAA
ATCGGTTTCACCCTTACAGCAAGTGCTGGATGTCCCGGAAGGTGAAATGGCGGATCGCATCGAGTTACCCGCCTCCTGGC
ATAACGATGCTATGACGCATCGTTACTTACGCAAAATGGAATCCAGTCCGTTTATAAATCATCTGGTTGATGGAACGTTG
CCGCTTATCTGGGCGAAAACACGTTTATTAAGTGATGATCCGGCGAAAGGGGAGGGCAAGGCAAAACGGCATTCACTGTT
ACCGCAGCGCCTGTTCGATATCATGGGCTCACCCAGTGAACGCATCGATATTATCTCTTCCTATTTTGTACCGACACGCG
CAGGTGTGGCGCAACTCTTACGGATGGTGAGAAAAGGGGTAAAGATTGCGATCCTAACCAATTCTCTTGCCGCTAACGAT
GTTGCTGTCGTCCATGCCGGATACGCGCGCTGGCGCAAAAAATTGCTCCGCTATGGCGTGGAATTATATGAACTCAAGCC
GACGCGTGAACAAAGTAGTACGTTACACGATCGCGGCATAACCGGTAATTCCGGAGCCAGCCTGCATGCTAAAACCTTTA
GCATCGATGGTAAAACGGTGTTTATCGGCTCTTTCAATTTCGATCCGCGTTCAACATTGCTCAATACTGAAATGGGCTTC
GTGATAGAGAGCGAAACGCTGGCACAGTTAATTGATAAACGCTTTATTCAGAGCCAGTATGATGCGGCCTGGCAGCTCCG
TCTGGACAGGTGGGGACGGATCAACTGGGTTGATCGTCATGCAAAGAAAGAGATTATTCTCAAAAAAGAACCCGCCACCA
GTTTCTGGAAGCGGGTTATGGTCAGACTGGCGTCGATATTGCCCGTGGAATGGTTATTGTAA

Upstream 100 bases:

>100_bases
ACCCGTCACGCTTTACCCGAACAGGTATACTTTGTCTGTTATGATGAAGAAAACGCCCACCTCTACGAAAGACTCCTTAC
CCAACAAGGAGATGAATGAT

Downstream 100 bases:

>100_bases
ATGTGGCTTAACGGGCTGGTGCTTTATCGTTCTCACGCTTAACAACCGGTTTACCAGAAAACAAAAACTTCAGTAACGGG
ATGCGTAAATGAATTTCATA

Product: putative hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 473; Mature: 472

Protein sequence:

>473_residues
MPRLASAVLPLCSQHPGQCGLFPLEKSLDAFAARYRLAEMAEHTLDVQYYIWQDDMSGRLLFSALLAAAKRGVRVRLLLD
DNNTPGLDDILRLLDSHPRIEVRLFNPFSFRLLRPLGYITDFSRLNRRMHNKSFTVDGVVTLVGGRNIGDAYFGAGEEPL
FSDLDVMAIGPVVEDVADDFARYWYCKSVSPLQQVLDVPEGEMADRIELPASWHNDAMTHRYLRKMESSPFINHLVDGTL
PLIWAKTRLLSDDPAKGEGKAKRHSLLPQRLFDIMGSPSERIDIISSYFVPTRAGVAQLLRMVRKGVKIAILTNSLAAND
VAVVHAGYARWRKKLLRYGVELYELKPTREQSSTLHDRGITGNSGASLHAKTFSIDGKTVFIGSFNFDPRSTLLNTEMGF
VIESETLAQLIDKRFIQSQYDAAWQLRLDRWGRINWVDRHAKKEIILKKEPATSFWKRVMVRLASILPVEWLL

Sequences:

>Translated_473_residues
MPRLASAVLPLCSQHPGQCGLFPLEKSLDAFAARYRLAEMAEHTLDVQYYIWQDDMSGRLLFSALLAAAKRGVRVRLLLD
DNNTPGLDDILRLLDSHPRIEVRLFNPFSFRLLRPLGYITDFSRLNRRMHNKSFTVDGVVTLVGGRNIGDAYFGAGEEPL
FSDLDVMAIGPVVEDVADDFARYWYCKSVSPLQQVLDVPEGEMADRIELPASWHNDAMTHRYLRKMESSPFINHLVDGTL
PLIWAKTRLLSDDPAKGEGKAKRHSLLPQRLFDIMGSPSERIDIISSYFVPTRAGVAQLLRMVRKGVKIAILTNSLAAND
VAVVHAGYARWRKKLLRYGVELYELKPTREQSSTLHDRGITGNSGASLHAKTFSIDGKTVFIGSFNFDPRSTLLNTEMGF
VIESETLAQLIDKRFIQSQYDAAWQLRLDRWGRINWVDRHAKKEIILKKEPATSFWKRVMVRLASILPVEWLL
>Mature_472_residues
PRLASAVLPLCSQHPGQCGLFPLEKSLDAFAARYRLAEMAEHTLDVQYYIWQDDMSGRLLFSALLAAAKRGVRVRLLLDD
NNTPGLDDILRLLDSHPRIEVRLFNPFSFRLLRPLGYITDFSRLNRRMHNKSFTVDGVVTLVGGRNIGDAYFGAGEEPLF
SDLDVMAIGPVVEDVADDFARYWYCKSVSPLQQVLDVPEGEMADRIELPASWHNDAMTHRYLRKMESSPFINHLVDGTLP
LIWAKTRLLSDDPAKGEGKAKRHSLLPQRLFDIMGSPSERIDIISSYFVPTRAGVAQLLRMVRKGVKIAILTNSLAANDV
AVVHAGYARWRKKLLRYGVELYELKPTREQSSTLHDRGITGNSGASLHAKTFSIDGKTVFIGSFNFDPRSTLLNTEMGFV
IESETLAQLIDKRFIQSQYDAAWQLRLDRWGRINWVDRHAKKEIILKKEPATSFWKRVMVRLASILPVEWLL

Specific function: Unknown

COG id: COG1502

COG function: function code I; Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PLD phosphodiesterase domains

Homologues:

Organism=Escherichia coli, GI87081826, Length=473, Percent_Identity=100, Blast_Score=970, Evalue=0.0,
Organism=Escherichia coli, GI1787007, Length=399, Percent_Identity=23.0576441102757, Blast_Score=77, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YMDC_ECOLI (P75919)

Other databases:

- EMBL:   U00096
- EMBL:   AP009048
- PIR:   C64847
- RefSeq:   AP_001673.1
- RefSeq:   NP_415564.2
- ProteinModelPortal:   P75919
- DIP:   DIP-12712N
- STRING:   P75919
- EnsemblBacteria:   EBESCT00000000007
- EnsemblBacteria:   EBESCT00000016095
- GeneID:   947321
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW5150
- KEGG:   eco:b1046
- EchoBASE:   EB3634
- EcoGene:   EG13875
- eggNOG:   COG1502
- GeneTree:   EBGT00050000009472
- HOGENOM:   HBG303422
- OMA:   PNKEMND
- ProtClustDB:   CLSK879946
- BioCyc:   EcoCyc:G6551-MONOMER
- Genevestigator:   P75919
- InterPro:   IPR001736
- SMART:   SM00155

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 53667; Mature: 53535

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: PS50035 PLD

Important sites: ACT_SITE 130-130 ACT_SITE 132-132 ACT_SITE 137-137 ACT_SITE 369-369 ACT_SITE 371-371 ACT_SITE 376-376

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRLASAVLPLCSQHPGQCGLFPLEKSLDAFAARYRLAEMAEHTLDVQYYIWQDDMSGRL
CCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCEEEEEEEECCCCCHH
LFSALLAAAKRGVRVRLLLDDNNTPGLDDILRLLDSHPRIEVRLFNPFSFRLLRPLGYIT
HHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHH
DFSRLNRRMHNKSFTVDGVVTLVGGRNIGDAYFGAGEEPLFSDLDVMAIGPVVEDVADDF
HHHHHHHHHCCCCEEECEEEEEECCCCCCCHHCCCCCCCCCCCCCCEEEHHHHHHHHHHH
ARYWYCKSVSPLQQVLDVPEGEMADRIELPASWHNDAMTHRYLRKMESSPFINHLVDGTL
HHHHHHCCCHHHHHHHCCCCCCCCCCEECCCCCCCHHHHHHHHHHHCCCCHHHHHHCCCH
PLIWAKTRLLSDDPAKGEGKAKRHSLLPQRLFDIMGSPSERIDIISSYFVPTRAGVAQLL
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHH
RMVRKGVKIAILTNSLAANDVAVVHAGYARWRKKLLRYGVELYELKPTREQSSTLHDRGI
HHHHCCCEEEEEECCCCCCCEEEEECCHHHHHHHHHHCCCEEEEECCCHHHHHHHHHCCC
TGNSGASLHAKTFSIDGKTVFIGSFNFDPRSTLLNTEMGFVIESETLAQLIDKRFIQSQY
CCCCCCEEEEEEEEECCCEEEEEECCCCCHHHHCCCCCCEEECHHHHHHHHHHHHHHHHC
DAAWQLRLDRWGRINWVDRHAKKEIILKKEPATSFWKRVMVRLASILPVEWLL
CCCEEEEECCCCCCCHHHHHHHHCEEEECCCHHHHHHHHHHHHHHHCCHHHCC
>Mature Secondary Structure 
PRLASAVLPLCSQHPGQCGLFPLEKSLDAFAARYRLAEMAEHTLDVQYYIWQDDMSGRL
CCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCEEEEEEEECCCCCHH
LFSALLAAAKRGVRVRLLLDDNNTPGLDDILRLLDSHPRIEVRLFNPFSFRLLRPLGYIT
HHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHH
DFSRLNRRMHNKSFTVDGVVTLVGGRNIGDAYFGAGEEPLFSDLDVMAIGPVVEDVADDF
HHHHHHHHHCCCCEEECEEEEEECCCCCCCHHCCCCCCCCCCCCCCEEEHHHHHHHHHHH
ARYWYCKSVSPLQQVLDVPEGEMADRIELPASWHNDAMTHRYLRKMESSPFINHLVDGTL
HHHHHHCCCHHHHHHHCCCCCCCCCCEECCCCCCCHHHHHHHHHHHCCCCHHHHHHCCCH
PLIWAKTRLLSDDPAKGEGKAKRHSLLPQRLFDIMGSPSERIDIISSYFVPTRAGVAQLL
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHH
RMVRKGVKIAILTNSLAANDVAVVHAGYARWRKKLLRYGVELYELKPTREQSSTLHDRGI
HHHHCCCEEEEEECCCCCCCEEEEECCHHHHHHHHHHCCCEEEEECCCHHHHHHHHHCCC
TGNSGASLHAKTFSIDGKTVFIGSFNFDPRSTLLNTEMGFVIESETLAQLIDKRFIQSQY
CCCCCCEEEEEEEEECCCEEEEEECCCCCHHHHCCCCCCEEECHHHHHHHHHHHHHHHHC
DAAWQLRLDRWGRINWVDRHAKKEIILKKEPATSFWKRVMVRLASILPVEWLL
CCCEEEEECCCCCCCHHHHHHHHCEEEECCCHHHHHHHHHHHHHHHCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503