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The map label for this gene is kdpA

Identifier: 218694124

GI number: 218694124

Start: 742791

End: 744464

Strand: Reverse

Name: kdpA

Synonym: EC55989_0682

Alternate gene names: 218694124

Gene position: 744464-742791 (Counterclockwise)

Preceding gene: 218694132

Following gene: 218694123

Centisome position: 14.44

GC content: 55.5

Gene sequence:

>1674_bases
ATGGCTGCGCAAGGGTTCTTACTGATCGCCACGTTTTTACTGGTGTTAATGGTGCTGGCGCGTCCTTTAGGCAGCGGGCT
GGCGCGGCTGATTAATGACATTCCTCTTCCAGGTACAGCGGGCGTTGAACGTATACTCTTTCGTTTACCTGGCGTCTCTG
ACCATGAGATGAACTGGAAGCAATATCTTTGTGCCATTCTCGGCCTGAACATGCTGGGGCTGGCGGTGCTGTTTTTTATG
TTGCTCGGTCAGCACTATCTGCCGCTTAATCCACAGCAGTTGCCGGGGCTGTCGTGGGATCTGGCGCTGAATACCGCCGT
CAGCTTTGTCACGAATACCAACTGGCAATCTTACAGCGGTGAAACCACGTTGAGCTATTTCAGCCAGATGGCTGGCTTAA
CGGTGCAAAACTTTCTTTCTGCCGCCAGCGGGATTGCGGTGATTTTTGCCCTCATCCGTGCGTTTACCCGCCAGAGCATG
AGCACACTCGGGAATGCCTGGGTCGATCTGCTACGCATCACGTTATGGGTGCTCGTCCCTGTGGCGTTGTTGATCGCACT
GTTTTTTATTCAACAAGGTGCGCTGCAAAACTTTCAGCCTTATCAGGCTGTGAATACCGTTGAAGGAGCGCAACAGCTGT
TACCCATGGGGCCTGTAGCTTCTCAGGAAGCGATCAAGATGCTCGGTACTAACGGCGGTGGCTTCTTTAATGCCAACTCG
TCGCATCCGTTTGAAAACCCAACCGCACTGACCAACTTCGTGCAGATGCTGGCGATCTTCTTGATCCCAACGGCGCTGTG
CTTTGCCTTTGGTGAAGTGACGGGCGATCGCCGCCAGGGGCGCATGTTGCTGTGGGCGATGTCAGTGATTTTTGTCATCT
GCGTAGGCGTGGTGATGTGGGCAGAAGTTCAGGGTAATCCTCATCTGCTGGCGCTCGGCGCAGACAGCAGCATCAATATG
GAAGGTAAAGAGAGCCGTTTCGGCGTGCTGGTCAGTAGCCTGTTTGCGGTCGTGACTACGGCGGCTTCCTGTGGCGCGGT
GATTGCGATGCATGATTCGTTTACCGCTCTCGGTGGCATGGTGCCGATGTGGCTGATGCAAATTGGTGAAGTGGTGTTCG
GCGGTGTCGGTTCTGGTCTTTACGGCATGATGCTGTTTGTCCTGCTGGCGGTGTTTATTGCCGGGCTGATGATTGGTCGT
ACACCGGAATATCTGGGTAAAAAAATCGACGTACGCGAGATGAAACTGACTGCACTGGCGATTCTGGTTACCCCGACGCT
GGTGCTGATGGGCGCGGCGCTGGCAATGATGACCGACGCCGGACGTAGCGCCATGCTCAACCCTGGCCCGCATGGTTTTA
GCGAAGTGCTGTACGCCGTGTCATCCGCCGCTAACAACAACGGCAGCGCCTTTGCCGGATTAAGCGCCAACTCCCCGTTC
TGGAACTGTTTACTGGCGTTCTGCATGTTTGTCGGTCGCTTCGGGGTGATTATCCCGGTGATGGCAATTGCCGGTTCGCT
GGTGAGTAAAAAGAGCCAACCCGCCAGCTCCGGCACGCTGCCAACGCACGGCCCGCTGTTTGTTGGCCTGTTAATCGGCA
CCGTGTTGCTGGTTGGCGCACTGACCTTTATCCCTGCCCTGGCGCTTGGTCCGGTGGCGGAATATCTCTCCTGA

Upstream 100 bases:

>100_bases
GGAGGTGCACTGTGAGTGCAGGCGTGATAACCGGCGTATTGCTGGTGTTTTTATTACTGGGTTATCTGGTTTATGCCCTG
ATCAATGCGGAGGCGTTCTG

Downstream 100 bases:

>100_bases
TGATATTGAGTGAGCACTGAATATGAGTCGTAAACAACTGGCGCTATTCGAACCAACACTTGTCGTTCAGGCGCTGAAAG
AAGCGGTGAAAAAATTAAAC

Product: potassium-transporting ATPase subunit A

Products: NA

Alternate protein names: ATP phosphohydrolase [potassium-transporting] A chain; Potassium-binding and translocating subunit A; Potassium-translocating ATPase A chain

Number of amino acids: Translated: 557; Mature: 556

Protein sequence:

>557_residues
MAAQGFLLIATFLLVLMVLARPLGSGLARLINDIPLPGTAGVERILFRLPGVSDHEMNWKQYLCAILGLNMLGLAVLFFM
LLGQHYLPLNPQQLPGLSWDLALNTAVSFVTNTNWQSYSGETTLSYFSQMAGLTVQNFLSAASGIAVIFALIRAFTRQSM
STLGNAWVDLLRITLWVLVPVALLIALFFIQQGALQNFQPYQAVNTVEGAQQLLPMGPVASQEAIKMLGTNGGGFFNANS
SHPFENPTALTNFVQMLAIFLIPTALCFAFGEVTGDRRQGRMLLWAMSVIFVICVGVVMWAEVQGNPHLLALGADSSINM
EGKESRFGVLVSSLFAVVTTAASCGAVIAMHDSFTALGGMVPMWLMQIGEVVFGGVGSGLYGMMLFVLLAVFIAGLMIGR
TPEYLGKKIDVREMKLTALAILVTPTLVLMGAALAMMTDAGRSAMLNPGPHGFSEVLYAVSSAANNNGSAFAGLSANSPF
WNCLLAFCMFVGRFGVIIPVMAIAGSLVSKKSQPASSGTLPTHGPLFVGLLIGTVLLVGALTFIPALALGPVAEYLS

Sequences:

>Translated_557_residues
MAAQGFLLIATFLLVLMVLARPLGSGLARLINDIPLPGTAGVERILFRLPGVSDHEMNWKQYLCAILGLNMLGLAVLFFM
LLGQHYLPLNPQQLPGLSWDLALNTAVSFVTNTNWQSYSGETTLSYFSQMAGLTVQNFLSAASGIAVIFALIRAFTRQSM
STLGNAWVDLLRITLWVLVPVALLIALFFIQQGALQNFQPYQAVNTVEGAQQLLPMGPVASQEAIKMLGTNGGGFFNANS
SHPFENPTALTNFVQMLAIFLIPTALCFAFGEVTGDRRQGRMLLWAMSVIFVICVGVVMWAEVQGNPHLLALGADSSINM
EGKESRFGVLVSSLFAVVTTAASCGAVIAMHDSFTALGGMVPMWLMQIGEVVFGGVGSGLYGMMLFVLLAVFIAGLMIGR
TPEYLGKKIDVREMKLTALAILVTPTLVLMGAALAMMTDAGRSAMLNPGPHGFSEVLYAVSSAANNNGSAFAGLSANSPF
WNCLLAFCMFVGRFGVIIPVMAIAGSLVSKKSQPASSGTLPTHGPLFVGLLIGTVLLVGALTFIPALALGPVAEYLS
>Mature_556_residues
AAQGFLLIATFLLVLMVLARPLGSGLARLINDIPLPGTAGVERILFRLPGVSDHEMNWKQYLCAILGLNMLGLAVLFFML
LGQHYLPLNPQQLPGLSWDLALNTAVSFVTNTNWQSYSGETTLSYFSQMAGLTVQNFLSAASGIAVIFALIRAFTRQSMS
TLGNAWVDLLRITLWVLVPVALLIALFFIQQGALQNFQPYQAVNTVEGAQQLLPMGPVASQEAIKMLGTNGGGFFNANSS
HPFENPTALTNFVQMLAIFLIPTALCFAFGEVTGDRRQGRMLLWAMSVIFVICVGVVMWAEVQGNPHLLALGADSSINME
GKESRFGVLVSSLFAVVTTAASCGAVIAMHDSFTALGGMVPMWLMQIGEVVFGGVGSGLYGMMLFVLLAVFIAGLMIGRT
PEYLGKKIDVREMKLTALAILVTPTLVLMGAALAMMTDAGRSAMLNPGPHGFSEVLYAVSSAANNNGSAFAGLSANSPFW
NCLLAFCMFVGRFGVIIPVMAIAGSLVSKKSQPASSGTLPTHGPLFVGLLIGTVLLVGALTFIPALALGPVAEYLS

Specific function: One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions

COG id: COG2060

COG function: function code P; K+-transporting ATPase, A chain

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdpA family

Homologues:

Organism=Escherichia coli, GI1786915, Length=557, Percent_Identity=98.3842010771993, Blast_Score=1088, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ATKA_ECO24 (A7ZJ81)

Other databases:

- EMBL:   CP000800
- RefSeq:   YP_001461860.1
- STRING:   A7ZJ81
- EnsemblBacteria:   EBESCT00000023248
- GeneID:   5587423
- GenomeReviews:   CP000800_GR
- KEGG:   ecw:EcE24377A_0724
- eggNOG:   COG2060
- GeneTree:   EBGT00050000010253
- HOGENOM:   HBG291815
- OMA:   MSYLTQM
- ProtClustDB:   PRK05482
- BioCyc:   ECOL331111:ECE24377A_0724-MONOMER
- HAMAP:   MF_00275
- InterPro:   IPR004623
- PIRSF:   PIRSF001294
- TIGRFAMs:   TIGR00680

Pfam domain/function: PF03814 KdpA

EC number: =3.6.3.12

Molecular weight: Translated: 59162; Mature: 59031

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x17e99cb0)-; HASH(0x17b49af0)-; HASH(0x182b90f4)-; HASH(0x182c3528)-; HASH(0x182c3714)-; HASH(0x182b9364)-; HASH(0x182c381c)-; HASH(0x1679f238)-; HASH(0x1789c884)-; HASH(0x1707e8e0)-; HASH(0x182a2cc4)-; HASH(0x182b9220)-;

Cys/Met content:

1.1 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAQGFLLIATFLLVLMVLARPLGSGLARLINDIPLPGTAGVERILFRLPGVSDHEMNWK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCHH
QYLCAILGLNMLGLAVLFFMLLGQHYLPLNPQQLPGLSWDLALNTAVSFVTNTNWQSYSG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCC
ETTLSYFSQMAGLTVQNFLSAASGIAVIFALIRAFTRQSMSTLGNAWVDLLRITLWVLVP
CHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VALLIALFFIQQGALQNFQPYQAVNTVEGAQQLLPMGPVASQEAIKMLGTNGGGFFNANS
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCC
SHPFENPTALTNFVQMLAIFLIPTALCFAFGEVTGDRRQGRMLLWAMSVIFVICVGVVMW
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCHHHHHHHHHHHHHHHHHHHH
AEVQGNPHLLALGADSSINMEGKESRFGVLVSSLFAVVTTAASCGAVIAMHDSFTALGGM
HHCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHH
VPMWLMQIGEVVFGGVGSGLYGMMLFVLLAVFIAGLMIGRTPEYLGKKIDVREMKLTALA
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHH
ILVTPTLVLMGAALAMMTDAGRSAMLNPGPHGFSEVLYAVSSAANNNGSAFAGLSANSPF
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEECCCCCCHH
WNCLLAFCMFVGRFGVIIPVMAIAGSLVSKKSQPASSGTLPTHGPLFVGLLIGTVLLVGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
LTFIPALALGPVAEYLS
HHHHHHHHHHHHHHHHH
>Mature Secondary Structure 
AAQGFLLIATFLLVLMVLARPLGSGLARLINDIPLPGTAGVERILFRLPGVSDHEMNWK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCHH
QYLCAILGLNMLGLAVLFFMLLGQHYLPLNPQQLPGLSWDLALNTAVSFVTNTNWQSYSG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCC
ETTLSYFSQMAGLTVQNFLSAASGIAVIFALIRAFTRQSMSTLGNAWVDLLRITLWVLVP
CHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VALLIALFFIQQGALQNFQPYQAVNTVEGAQQLLPMGPVASQEAIKMLGTNGGGFFNANS
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCC
SHPFENPTALTNFVQMLAIFLIPTALCFAFGEVTGDRRQGRMLLWAMSVIFVICVGVVMW
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCHHHHHHHHHHHHHHHHHHHH
AEVQGNPHLLALGADSSINMEGKESRFGVLVSSLFAVVTTAASCGAVIAMHDSFTALGGM
HHCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHH
VPMWLMQIGEVVFGGVGSGLYGMMLFVLLAVFIAGLMIGRTPEYLGKKIDVREMKLTALA
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHH
ILVTPTLVLMGAALAMMTDAGRSAMLNPGPHGFSEVLYAVSSAANNNGSAFAGLSANSPF
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEECCCCCCHH
WNCLLAFCMFVGRFGVIIPVMAIAGSLVSKKSQPASSGTLPTHGPLFVGLLIGTVLLVGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
LTFIPALALGPVAEYLS
HHHHHHHHHHHHHHHHH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA