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The map label for this gene is allB

Identifier: 218693975

GI number: 218693975

Start: 567041

End: 568402

Strand: Direct

Name: allB

Synonym: EC55989_0526

Alternate gene names: 218693975

Gene position: 567041-568402 (Clockwise)

Preceding gene: 218693974

Following gene: 218693976

Centisome position: 11.0

GC content: 51.91

Gene sequence:

>1362_bases
ATGTCTTTTGATTTAATCATTAAAAACGGCACCGTTATTTTAGAAAACGAAGCTCGCGTTGTAGATATCGCCGTTAAAGG
CGGGAAAATTGCTGCTATCGGTCAGGATCTGGGCGATGCAAAAGAAGTTATGGATGCGTCTGGTCTGGTGGTTTCGCCGG
GCATGGTTGATGCGCACACCCATATTTCTGAACCGGGTCGTAGCCACTGGGAAGGTTATGAAACCGGTACTCGCGCAGCG
GCAAAAGGTGGTATCACCACCATGATCGAAATGCCGCTCAACCAGCTGCCTGCAACGGTTGACCGCGCTTCAATTGAACT
GAAGTTCGATGCCGCTAAAGGCAAGCTGACTATCGATGCGGCACAACTCGGTGGCCTGGTGTCTTACAACATCGACCGTC
TGCATGAGCTGGATGAAGTGGGCGTTGTCGGCTTCAAATGCTTCGTTGCGACCTGTGGCGATCGCGGTATCGACAACGAC
TTCCGTGATGTAAACGACTGGCAGTTCTTCAAAGGTGCGCAGAAGCTGGGCGAACTGGGGCAGCCGGTGCTGGTGCACTG
CGAAAACGCGCTGATCTGTGACGCACTGGGCGAAGAAGCGAAACGTGAAGGTCGCGTAACTGCCCATGACTATGTGGCTT
CGCGTCCGGTATTTACCGAAGTGGAAGCGATTCGCCGCGTGCTGTATCTGGCGAAAGTTGCCGGTTGCCGTCTGCACGTT
TGCCATATCAGCAGCCCGGAAGGCGTTGAAGAAGTGACTCGTGCACGTCAGGAAGGTCAGGACGTTACTTGTGAATCCTG
CCCGCATTACTTTGTACTGGATACCGATCAGTTCGAAGAAATCGGCACTCTGGCGAAGTGTTCACCGCCGATCCGCGATC
TGGAAAACCAGAAAGGCATGTGGGAAAAACTGTTTAACGGTGAAATCGACTGCCTGGTTTCCGACCACTCACCATGCCCT
CCGGAAATGAAAGCCGGCAACATCATGGAAGCATGGGGCGGTATTGCCGGTCTGCAAAACTGTATGGACGTGATGTTCGA
TGAAGCGGTACAGAAACGCGGAATGTCTCTGCCAATGTTCGGCAAATTAATGGCGACTAACGCAGCAGATATTTTCGGTC
TGCAGCAAAAAGGCCGTATCGCCCCAGGAAAAGATGCCGACTTCGTCTTCATTCAGCCGAATAGCAGCTATGTTCTTACC
AATGACGATCTGGAATATCGCCACAAAGTCAGCCCGTATGTTGGCCGTACCATTGGCGCGCGTATCACGAAAACCATCTT
ACGTGGTGATGTGATTTACGACATTGAACAGGGCTTCCCTGTTGCGCCGAAAGGTCAATTTATCCTTAAACATCAGCAGT
AA

Upstream 100 bases:

>100_bases
CAACAGCAGAAAAAACAGGAGAGCAAAAAACCATAGGTTAATTAATCCCGATATTGAACATTGAGTTAAAAACCAATCTG
TATTTTACAAGGAGTTTGTT

Downstream 100 bases:

>100_bases
TCTGGCCCCTGCAATGCCCGTCCTTGCGGCGGGCATTCTCCGGTTAAGGTGTGTTTATGTTCAATTTTGCAGTGAGCCGC
GAAAGCCTGTTATCAGGATT

Product: allantoinase

Products: NA

Alternate protein names: Allantoin-utilizing enzyme [H]

Number of amino acids: Translated: 453; Mature: 452

Protein sequence:

>453_residues
MSFDLIIKNGTVILENEARVVDIAVKGGKIAAIGQDLGDAKEVMDASGLVVSPGMVDAHTHISEPGRSHWEGYETGTRAA
AKGGITTMIEMPLNQLPATVDRASIELKFDAAKGKLTIDAAQLGGLVSYNIDRLHELDEVGVVGFKCFVATCGDRGIDND
FRDVNDWQFFKGAQKLGELGQPVLVHCENALICDALGEEAKREGRVTAHDYVASRPVFTEVEAIRRVLYLAKVAGCRLHV
CHISSPEGVEEVTRARQEGQDVTCESCPHYFVLDTDQFEEIGTLAKCSPPIRDLENQKGMWEKLFNGEIDCLVSDHSPCP
PEMKAGNIMEAWGGIAGLQNCMDVMFDEAVQKRGMSLPMFGKLMATNAADIFGLQQKGRIAPGKDADFVFIQPNSSYVLT
NDDLEYRHKVSPYVGRTIGARITKTILRGDVIYDIEQGFPVAPKGQFILKHQQ

Sequences:

>Translated_453_residues
MSFDLIIKNGTVILENEARVVDIAVKGGKIAAIGQDLGDAKEVMDASGLVVSPGMVDAHTHISEPGRSHWEGYETGTRAA
AKGGITTMIEMPLNQLPATVDRASIELKFDAAKGKLTIDAAQLGGLVSYNIDRLHELDEVGVVGFKCFVATCGDRGIDND
FRDVNDWQFFKGAQKLGELGQPVLVHCENALICDALGEEAKREGRVTAHDYVASRPVFTEVEAIRRVLYLAKVAGCRLHV
CHISSPEGVEEVTRARQEGQDVTCESCPHYFVLDTDQFEEIGTLAKCSPPIRDLENQKGMWEKLFNGEIDCLVSDHSPCP
PEMKAGNIMEAWGGIAGLQNCMDVMFDEAVQKRGMSLPMFGKLMATNAADIFGLQQKGRIAPGKDADFVFIQPNSSYVLT
NDDLEYRHKVSPYVGRTIGARITKTILRGDVIYDIEQGFPVAPKGQFILKHQQ
>Mature_452_residues
SFDLIIKNGTVILENEARVVDIAVKGGKIAAIGQDLGDAKEVMDASGLVVSPGMVDAHTHISEPGRSHWEGYETGTRAAA
KGGITTMIEMPLNQLPATVDRASIELKFDAAKGKLTIDAAQLGGLVSYNIDRLHELDEVGVVGFKCFVATCGDRGIDNDF
RDVNDWQFFKGAQKLGELGQPVLVHCENALICDALGEEAKREGRVTAHDYVASRPVFTEVEAIRRVLYLAKVAGCRLHVC
HISSPEGVEEVTRARQEGQDVTCESCPHYFVLDTDQFEEIGTLAKCSPPIRDLENQKGMWEKLFNGEIDCLVSDHSPCPP
EMKAGNIMEAWGGIAGLQNCMDVMFDEAVQKRGMSLPMFGKLMATNAADIFGLQQKGRIAPGKDADFVFIQPNSSYVLTN
DDLEYRHKVSPYVGRTIGARITKTILRGDVIYDIEQGFPVAPKGQFILKHQQ

Specific function: Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring [H]

COG id: COG0044

COG function: function code F; Dihydroorotase and related cyclic amidohydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHOase family. Allantoinase subfamily [H]

Homologues:

Organism=Homo sapiens, GI4503375, Length=469, Percent_Identity=27.2921108742004, Blast_Score=132, Evalue=7e-31,
Organism=Homo sapiens, GI4503379, Length=477, Percent_Identity=25.9958071278826, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI4503051, Length=418, Percent_Identity=28.4688995215311, Blast_Score=119, Evalue=7e-27,
Organism=Homo sapiens, GI62422571, Length=420, Percent_Identity=28.0952380952381, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI18105007, Length=422, Percent_Identity=23.696682464455, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI19923821, Length=456, Percent_Identity=25.8771929824561, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI4503377, Length=431, Percent_Identity=27.1461716937355, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI190194363, Length=433, Percent_Identity=27.9445727482679, Blast_Score=105, Evalue=7e-23,
Organism=Escherichia coli, GI1786722, Length=453, Percent_Identity=99.1169977924945, Blast_Score=933, Evalue=0.0,
Organism=Escherichia coli, GI87082175, Length=444, Percent_Identity=29.954954954955, Blast_Score=172, Evalue=4e-44,
Organism=Caenorhabditis elegans, GI71989490, Length=471, Percent_Identity=26.5392781316348, Blast_Score=129, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI17539558, Length=469, Percent_Identity=26.865671641791, Blast_Score=129, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI193204318, Length=381, Percent_Identity=24.1469816272966, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI86575075, Length=439, Percent_Identity=24.1457858769932, Blast_Score=98, Evalue=8e-21,
Organism=Saccharomyces cerevisiae, GI6322218, Length=418, Percent_Identity=34.9282296650718, Blast_Score=253, Evalue=5e-68,
Organism=Drosophila melanogaster, GI18859883, Length=430, Percent_Identity=34.1860465116279, Blast_Score=205, Evalue=7e-53,
Organism=Drosophila melanogaster, GI221377917, Length=470, Percent_Identity=26.5957446808511, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI17137462, Length=465, Percent_Identity=26.2365591397849, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24642586, Length=397, Percent_Identity=23.6775818639798, Blast_Score=122, Evalue=5e-28,
Organism=Drosophila melanogaster, GI24644287, Length=304, Percent_Identity=26.9736842105263, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24644289, Length=263, Percent_Identity=26.615969581749, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017593
- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.2.5 [H]

Molecular weight: Translated: 49586; Mature: 49455

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFDLIIKNGTVILENEARVVDIAVKGGKIAAIGQDLGDAKEVMDASGLVVSPGMVDAHT
CCEEEEEECCEEEEECCCEEEEEEECCCEEEEECCCCCHHHHHHCCCCEEECCCCCCCCC
HISEPGRSHWEGYETGTRAAAKGGITTMIEMPLNQLPATVDRASIELKFDAAKGKLTIDA
CCCCCCCHHCCCCCCCCHHHHCCCCEEEEECCHHHCCCCCCCEEEEEEEECCCCEEEEEH
AQLGGLVSYNIDRLHELDEVGVVGFKCFVATCGDRGIDNDFRDVNDWQFFKGAQKLGELG
HHHCCEEEECHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCC
QPVLVHCENALICDALGEEAKREGRVTAHDYVASRPVFTEVEAIRRVLYLAKVAGCRLHV
CCEEEEECCEEEEHHHHHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEEE
CHISSPEGVEEVTRARQEGQDVTCESCPHYFVLDTDQFEEIGTLAKCSPPIRDLENQKGM
EECCCCCCHHHHHHHHHCCCCCCHHCCCCEEEECCHHHHHHCCHHHCCCCHHHHHCCCCH
WEKLFNGEIDCLVSDHSPCPPEMKAGNIMEAWGGIAGLQNCMDVMFDEAVQKRGMSLPMF
HHHHHCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
GKLMATNAADIFGLQQKGRIAPGKDADFVFIQPNSSYVLTNDDLEYRHKVSPYVGRTIGA
HHHHHCCCHHHCCCCCCCCCCCCCCCCEEEECCCCCEEEECCCCHHHHCCCHHHHHHHHH
RITKTILRGDVIYDIEQGFPVAPKGQFILKHQQ
HHHHHHHCCCEEEEECCCCCCCCCCCEEEECCC
>Mature Secondary Structure 
SFDLIIKNGTVILENEARVVDIAVKGGKIAAIGQDLGDAKEVMDASGLVVSPGMVDAHT
CEEEEEECCEEEEECCCEEEEEEECCCEEEEECCCCCHHHHHHCCCCEEECCCCCCCCC
HISEPGRSHWEGYETGTRAAAKGGITTMIEMPLNQLPATVDRASIELKFDAAKGKLTIDA
CCCCCCCHHCCCCCCCCHHHHCCCCEEEEECCHHHCCCCCCCEEEEEEEECCCCEEEEEH
AQLGGLVSYNIDRLHELDEVGVVGFKCFVATCGDRGIDNDFRDVNDWQFFKGAQKLGELG
HHHCCEEEECHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCC
QPVLVHCENALICDALGEEAKREGRVTAHDYVASRPVFTEVEAIRRVLYLAKVAGCRLHV
CCEEEEECCEEEEHHHHHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEEE
CHISSPEGVEEVTRARQEGQDVTCESCPHYFVLDTDQFEEIGTLAKCSPPIRDLENQKGM
EECCCCCCHHHHHHHHHCCCCCCHHCCCCEEEECCHHHHHHCCHHHCCCCHHHHHCCCCH
WEKLFNGEIDCLVSDHSPCPPEMKAGNIMEAWGGIAGLQNCMDVMFDEAVQKRGMSLPMF
HHHHHCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
GKLMATNAADIFGLQQKGRIAPGKDADFVFIQPNSSYVLTNDDLEYRHKVSPYVGRTIGA
HHHHHCCCHHHCCCCCCCCCCCCCCCCEEEECCCCCEEEECCCCHHHHCCCHHHHHHHHH
RITKTILRGDVIYDIEQGFPVAPKGQFILKHQQ
HHHHHHHCCCEEEEECCCCCCCCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA