Click here to switch to the map view.

The map label for this gene is hha

Identifier: 218693922

GI number: 218693922

Start: 507401

End: 507865

Strand: Reverse

Name: hha

Synonym: EC55989_0473

Alternate gene names: 218693922

Gene position: 507865-507401 (Counterclockwise)

Preceding gene: 218693923

Following gene: 218693921

Centisome position: 9.85

GC content: 38.49

Gene sequence:

>465_bases
TTGAGCATATTGCGACCTTCGCACTTAATTACAAAATTAAGTATAATGAAGACAATAAGCTCATTGAGCAGATCGACGAA
TATCTGGATGACACCTTTATGTTGTTCAGTAGTTATGGTATTAATATGCAGGATCTTCAGAAATGGCGGAAGTCAGGTAA
TCGACTATTCCGTTGTTTTGTCAATGCGACGAAAGAGAATCCTGCGAGTTTATCTTGTTAGAATTATTACAACCATGGGT
AGAAGTATGTCCGAAAAACCTTTAACGAAAACCGATTATTTAATGCGTTTACGTCGTTGCCAGACAATTGACACGCTGGA
GCGTGTTATCGAGAAAAATAAATACGAATTATCAGATAATGAACTGGCGGTATTTTACTCAGCCGCAGATCACCGCCTCG
CCGAATTGACCATGAATAAACTATACGACAAGATCCCTTCCTCAGTATGGAAATTTATTCGCTAA

Upstream 100 bases:

>100_bases
GAAACCCTGTATCATGACTGCCTTGCAAACCTTGAAGAAAGCAATCATGGCTGGGTTAACGACCCAACCTCGGCGATCAA
CCTCCAGTTGAATGAACTGA

Downstream 100 bases:

>100_bases
TAAATAATTCGCTTTCGGAGCTATAACCGGCTGTTTATTAAGAATTTTATACTTTTCACCATGAAGACATACCCTATGTG
ATCTTTATCACACAGATGTA

Product: modulator of gene expression, with H-NS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 154; Mature: 153

Protein sequence:

>154_residues
MSILRPSHLITKLSIMKTISSLSRSTNIWMTPLCCSVVMVLICRIFRNGGSQVIDYSVVLSMRRKRILRVYLVRIITTMG
RSMSEKPLTKTDYLMRLRRCQTIDTLERVIEKNKYELSDNELAVFYSAADHRLAELTMNKLYDKIPSSVWKFIR

Sequences:

>Translated_154_residues
MSILRPSHLITKLSIMKTISSLSRSTNIWMTPLCCSVVMVLICRIFRNGGSQVIDYSVVLSMRRKRILRVYLVRIITTMG
RSMSEKPLTKTDYLMRLRRCQTIDTLERVIEKNKYELSDNELAVFYSAADHRLAELTMNKLYDKIPSSVWKFIR
>Mature_153_residues
SILRPSHLITKLSIMKTISSLSRSTNIWMTPLCCSVVMVLICRIFRNGGSQVIDYSVVLSMRRKRILRVYLVRIITTMGR
SMSEKPLTKTDYLMRLRRCQTIDTLERVIEKNKYELSDNELAVFYSAADHRLAELTMNKLYDKIPSSVWKFIR

Specific function: Down-regulates hemolysin production and can also stimulate transposition events in vivo. May bind DNA and influence DNA topology in response to environmental stimuli [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hha/ymoA/cnu family [H]

Homologues:

Organism=Escherichia coli, GI1786665, Length=72, Percent_Identity=100, Blast_Score=151, Evalue=2e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007985 [H]

Pfam domain/function: PF05321 HHA [H]

EC number: NA

Molecular weight: Translated: 18013; Mature: 17882

Theoretical pI: Translated: 10.65; Mature: 10.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
5.8 %Met     (Translated Protein)
8.4 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
7.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILRPSHLITKLSIMKTISSLSRSTNIWMTPLCCSVVMVLICRIFRNGGSQVIDYSVVL
CCCCCHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
SMRRKRILRVYLVRIITTMGRSMSEKPLTKTDYLMRLRRCQTIDTLERVIEKNKYELSDN
HHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
ELAVFYSAADHRLAELTMNKLYDKIPSSVWKFIR
CEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SILRPSHLITKLSIMKTISSLSRSTNIWMTPLCCSVVMVLICRIFRNGGSQVIDYSVVL
CCCCHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
SMRRKRILRVYLVRIITTMGRSMSEKPLTKTDYLMRLRRCQTIDTLERVIEKNKYELSDN
HHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
ELAVFYSAADHRLAELTMNKLYDKIPSSVWKFIR
CEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]