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The map label for this gene is fecC [H]

Identifier: 218692679

GI number: 218692679

Start: 5087106

End: 5088104

Strand: Reverse

Name: fecC [H]

Synonym: ECED1_5154

Alternate gene names: 218692679

Gene position: 5088104-5087106 (Counterclockwise)

Preceding gene: 218692680

Following gene: 218692678

Centisome position: 97.67

GC content: 60.66

Gene sequence:

>999_bases
ATGACCGCGATAAAACACCCGGTGCTGCTGTGGGGGCTTCCCATTGCAGCACTTATTATTATTTTCTGGCTGAGTCTGTT
TTGCTACTCGGCCATTCCTGTTTCCGGAGCAGATGCAACCCGCGCCCTGCTGCCTGGACACACGCCAACGCTACCAGAAG
CGCTGGTGCAAAACCTTCGTTTGCCACGAAGCCTGGTCGCCGTTCTGATCGGCGCAAGCCTGGCGCTCGCGGGCACGCTG
CTGCAAACCCTGACCCACAACCCAATGGCCTCTCCTTCACTGCTCGGCATTAACAGCGGCGCGGCGCTGGCTATGGCGCT
TACCAGCGCGCTAAGTCCGACGCCGATTGCAGGCTATTCTCTGTCGTTCATCGCGGCATGCGGGGGCGGCGTGAGCTGGC
TGCTGGTCATGACCGCAGGAGGCGGATTTCGTCATACCCATGACAGAAACAAACTGATCCTCGCGGGTATCGCGCTGTCG
GCCTTTTGTATGGGCCTTACCCGCATCACCCTGCTGCTGGCCGAAGATCATGCTTACGGCATCTTTTACTGGCTGGCAGG
CGGAGTGTCCCACGCCCGCTGGCAGGATGTCTGGCAGCTCTTGCCGGTGGTGGTCACTGCAGTCCCTGTCGTGTTGCTGC
TGGCGAATCAACTGAACCTGCTCAACCTCAGCGACAGCACCGCCCATACGCTGGGAGTGAACCTGACGAGGCTACGTTTG
GTCATCAATATGTTAGTGCTGCTTCTGGTTGGTGCGTGCGTCAGCGTGGCAGGTCCGGTGGCGTTTATCGGTCTGCTGGT
GCCACATCTGGCGCGCTTCTGGGCAGGCTTCGATCAGCGCAACGTACTGCCAGTGAGCATGCTGCTGGGGGCCACGCTGA
TGCTGCTGGCAGATGTACTCGCACGCGCGCTGGCCTTCCCCGGAGATCTGCCCGCAGGCGCAGTGCTGGCGCTGATTGGC
AGCCCTTGCTTTGTCTGGCTTGTGAGGAGGCGAGGATGA

Upstream 100 bases:

>100_bases
ACAGTAACACCTGGGCGCGGATGCGCGGTATTTTTGCTGCAGAGCGTATTGCCGCTGACACGGTAAAAATCTTCCACCAT
CAGCCGCTTACCGTTGTGAA

Downstream 100 bases:

>100_bases
AAATTGCGCTGGTTATTTTCATCACCCTTGCCCTGGCGGGCTGTGCGCTGTTATCACTCCATATGGGAGTGATCCCCGTG
CCGTGGCGCGCGCTGCTGAC

Product: iron-dicitrate transporter permease subunit

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: Iron(III) dicitrate transport system permease protein fecC [H]

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MTAIKHPVLLWGLPIAALIIIFWLSLFCYSAIPVSGADATRALLPGHTPTLPEALVQNLRLPRSLVAVLIGASLALAGTL
LQTLTHNPMASPSLLGINSGAALAMALTSALSPTPIAGYSLSFIAACGGGVSWLLVMTAGGGFRHTHDRNKLILAGIALS
AFCMGLTRITLLLAEDHAYGIFYWLAGGVSHARWQDVWQLLPVVVTAVPVVLLLANQLNLLNLSDSTAHTLGVNLTRLRL
VINMLVLLLVGACVSVAGPVAFIGLLVPHLARFWAGFDQRNVLPVSMLLGATLMLLADVLARALAFPGDLPAGAVLALIG
SPCFVWLVRRRG

Sequences:

>Translated_332_residues
MTAIKHPVLLWGLPIAALIIIFWLSLFCYSAIPVSGADATRALLPGHTPTLPEALVQNLRLPRSLVAVLIGASLALAGTL
LQTLTHNPMASPSLLGINSGAALAMALTSALSPTPIAGYSLSFIAACGGGVSWLLVMTAGGGFRHTHDRNKLILAGIALS
AFCMGLTRITLLLAEDHAYGIFYWLAGGVSHARWQDVWQLLPVVVTAVPVVLLLANQLNLLNLSDSTAHTLGVNLTRLRL
VINMLVLLLVGACVSVAGPVAFIGLLVPHLARFWAGFDQRNVLPVSMLLGATLMLLADVLARALAFPGDLPAGAVLALIG
SPCFVWLVRRRG
>Mature_331_residues
TAIKHPVLLWGLPIAALIIIFWLSLFCYSAIPVSGADATRALLPGHTPTLPEALVQNLRLPRSLVAVLIGASLALAGTLL
QTLTHNPMASPSLLGINSGAALAMALTSALSPTPIAGYSLSFIAACGGGVSWLLVMTAGGGFRHTHDRNKLILAGIALSA
FCMGLTRITLLLAEDHAYGIFYWLAGGVSHARWQDVWQLLPVVVTAVPVVLLLANQLNLLNLSDSTAHTLGVNLTRLRLV
INMLVLLLVGACVSVAGPVAFIGLLVPHLARFWAGFDQRNVLPVSMLLGATLMLLADVLARALAFPGDLPAGAVLALIGS
PCFVWLVRRRG

Specific function: Part of the binding-protein-dependent transport system for citrate-dependent Fe(3+). Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790741, Length=332, Percent_Identity=99.6987951807229, Blast_Score=640, Evalue=0.0,
Organism=Escherichia coli, GI1790740, Length=277, Percent_Identity=37.9061371841155, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI1786805, Length=277, Percent_Identity=38.9891696750903, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1786347, Length=290, Percent_Identity=35.1724137931034, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI1788004, Length=285, Percent_Identity=33.3333333333333, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1786804, Length=236, Percent_Identity=33.4745762711864, Blast_Score=100, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 34907; Mature: 34776

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAIKHPVLLWGLPIAALIIIFWLSLFCYSAIPVSGADATRALLPGHTPTLPEALVQNLR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCHHHHHHHCC
LPRSLVAVLIGASLALAGTLLQTLTHNPMASPSLLGINSGAALAMALTSALSPTPIAGYS
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCHHHHHHHHHHCCCCCCCCCH
LSFIAACGGGVSWLLVMTAGGGFRHTHDRNKLILAGIALSAFCMGLTRITLLLAEDHAYG
HHHHHHCCCCCEEEEEEECCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCE
IFYWLAGGVSHARWQDVWQLLPVVVTAVPVVLLLANQLNLLNLSDSTAHTLGVNLTRLRL
EHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHCCHHHHHHH
VINMLVLLLVGACVSVAGPVAFIGLLVPHLARFWAGFDQRNVLPVSMLLGATLMLLADVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
ARALAFPGDLPAGAVLALIGSPCFVWLVRRRG
HHHHCCCCCCCHHHHHHHHCCCHHHHHEECCC
>Mature Secondary Structure 
TAIKHPVLLWGLPIAALIIIFWLSLFCYSAIPVSGADATRALLPGHTPTLPEALVQNLR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCHHHHHHHCC
LPRSLVAVLIGASLALAGTLLQTLTHNPMASPSLLGINSGAALAMALTSALSPTPIAGYS
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCHHHHHHHHHHCCCCCCCCCH
LSFIAACGGGVSWLLVMTAGGGFRHTHDRNKLILAGIALSAFCMGLTRITLLLAEDHAYG
HHHHHHCCCCCEEEEEEECCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCE
IFYWLAGGVSHARWQDVWQLLPVVVTAVPVVLLLANQLNLLNLSDSTAHTLGVNLTRLRL
EHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHCCHHHHHHH
VINMLVLLLVGACVSVAGPVAFIGLLVPHLARFWAGFDQRNVLPVSMLLGATLMLLADVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
ARALAFPGDLPAGAVLALIGSPCFVWLVRRRG
HHHHCCCCCCCHHHHHHHHCCCHHHHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2651410; 7610040; 9278503 [H]