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The map label for this gene is alsE [H]

Identifier: 218692382

GI number: 218692382

Start: 4785179

End: 4785874

Strand: Reverse

Name: alsE [H]

Synonym: ECED1_4819

Alternate gene names: 218692382

Gene position: 4785874-4785179 (Counterclockwise)

Preceding gene: 218692383

Following gene: 218692381

Centisome position: 91.87

GC content: 48.28

Gene sequence:

>696_bases
ATGAAAATCTCCCCCTCGTTAATGTGTATGGATCTGCTGAAATTTAAAGAACAGATCGAATTTATCGACAGCCATGCCGA
TTACTTTCACATCGATATCATGGACGGCCACTTTGTGCCGAATCTGACGCTCTCACCGTTCTTCGTAAGCCAGGTAAAAA
AACTGGCGAGTAAACCGCTCGACTGCCATCTGATGGTAACGCGTCCGCAGGATTACATTGCTCAACTGGCACGTGCGGGG
GCTGATTTCATCACTTTGCATCCGGAAACTATCAACGGTCAGGCATTCCGCCTGATTGATGAAATCCGCCGTCATGGCAT
GAAAGTGGGGCTGATTCTTAATCCGGAAACGCCGGTTGAGGCCATGAAATACTATATCCATAAGGCTGATAAAATTACGG
TCATGACTGTCGATCCCGGTTTTGCCGGACAACCCTTCATTCCTGAAATGCTGGATAAAGTTGCCGAACTGAAGGCATGG
CGTGAACGAGAAGGTCTGGAGTACGAAATTGAGGTGGACGGTTCCTGCAACCAGGCAACTTACGAAAAACTAATGGCGGC
AGGGGCGGATGTCTTTATCGTCGGCACTTCCGGCCTGTTTAATCATGCGGAAAATATCGACGAAGCATGGAGAATTATGA
CCGCGCAGATTCTGGCTGCAAAAAGCGAGGTACAGCCTCATGCAAAAACAGCATAA

Upstream 100 bases:

>100_bases
ATTTTGCAGGTACAAACCTATTACCAACTGGTGGTGATGGGCGGATTAATTATCGCGGCTGTCGCCCTTGACCGTCTTAT
CAGTAAGTAAGGAATTGAAC

Downstream 100 bases:

>100_bases
CGTCGTAGCGGGCGTGGATATGGGGGCAACGCATATCCGCTTTTGTCTGCGGACAGCAGAAGGTGAAACGCTACACTGCG
AAAAAAAGCGGACCGCAGAA

Product: allulose-6-phosphate 3-epimerase

Products: fructose-6-phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MKISPSLMCMDLLKFKEQIEFIDSHADYFHIDIMDGHFVPNLTLSPFFVSQVKKLASKPLDCHLMVTRPQDYIAQLARAG
ADFITLHPETINGQAFRLIDEIRRHGMKVGLILNPETPVEAMKYYIHKADKITVMTVDPGFAGQPFIPEMLDKVAELKAW
REREGLEYEIEVDGSCNQATYEKLMAAGADVFIVGTSGLFNHAENIDEAWRIMTAQILAAKSEVQPHAKTA

Sequences:

>Translated_231_residues
MKISPSLMCMDLLKFKEQIEFIDSHADYFHIDIMDGHFVPNLTLSPFFVSQVKKLASKPLDCHLMVTRPQDYIAQLARAG
ADFITLHPETINGQAFRLIDEIRRHGMKVGLILNPETPVEAMKYYIHKADKITVMTVDPGFAGQPFIPEMLDKVAELKAW
REREGLEYEIEVDGSCNQATYEKLMAAGADVFIVGTSGLFNHAENIDEAWRIMTAQILAAKSEVQPHAKTA
>Mature_231_residues
MKISPSLMCMDLLKFKEQIEFIDSHADYFHIDIMDGHFVPNLTLSPFFVSQVKKLASKPLDCHLMVTRPQDYIAQLARAG
ADFITLHPETINGQAFRLIDEIRRHGMKVGLILNPETPVEAMKYYIHKADKITVMTVDPGFAGQPFIPEMLDKVAELKAW
REREGLEYEIEVDGSCNQATYEKLMAAGADVFIVGTSGLFNHAENIDEAWRIMTAQILAAKSEVQPHAKTA

Specific function: D-ALLOSE METABOLISM. ESSENTIAL FOR THIS PATHWAY. [C]

COG id: COG0036

COG function: function code G; Pentose-5-phosphate-3-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribulose-phosphate 3-epimerase family [H]

Homologues:

Organism=Homo sapiens, GI40385883, Length=199, Percent_Identity=40.2010050251256, Blast_Score=142, Evalue=3e-34,
Organism=Homo sapiens, GI219879828, Length=199, Percent_Identity=38.1909547738693, Blast_Score=132, Evalue=2e-31,
Organism=Homo sapiens, GI24307923, Length=153, Percent_Identity=33.3333333333333, Blast_Score=83, Evalue=2e-16,
Organism=Escherichia coli, GI1790523, Length=231, Percent_Identity=98.7012987012987, Blast_Score=478, Evalue=1e-136,
Organism=Escherichia coli, GI1789788, Length=197, Percent_Identity=37.0558375634518, Blast_Score=147, Evalue=4e-37,
Organism=Escherichia coli, GI1790754, Length=160, Percent_Identity=33.125, Blast_Score=98, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17552948, Length=200, Percent_Identity=37, Blast_Score=133, Evalue=7e-32,
Organism=Saccharomyces cerevisiae, GI6322341, Length=209, Percent_Identity=34.4497607655502, Blast_Score=123, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24586301, Length=198, Percent_Identity=37.3737373737374, Blast_Score=134, Evalue=6e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000056
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00834 Ribul_P_3_epim [H]

EC number: 5.1.3.- [C]

Molecular weight: Translated: 26023; Mature: 26023

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: PS01085 RIBUL_P_3_EPIMER_1 ; PS01086 RIBUL_P_3_EPIMER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKISPSLMCMDLLKFKEQIEFIDSHADYFHIDIMDGHFVPNLTLSPFFVSQVKKLASKPL
CCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCC
DCHLMVTRPQDYIAQLARAGADFITLHPETINGQAFRLIDEIRRHGMKVGLILNPETPVE
CEEEEEECCHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCHH
AMKYYIHKADKITVMTVDPGFAGQPFIPEMLDKVAELKAWREREGLEYEIEVDGSCNQAT
HHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHH
YEKLMAAGADVFIVGTSGLFNHAENIDEAWRIMTAQILAAKSEVQPHAKTA
HHHHHHCCCCEEEEECCHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MKISPSLMCMDLLKFKEQIEFIDSHADYFHIDIMDGHFVPNLTLSPFFVSQVKKLASKPL
CCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCC
DCHLMVTRPQDYIAQLARAGADFITLHPETINGQAFRLIDEIRRHGMKVGLILNPETPVE
CEEEEEECCHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCHH
AMKYYIHKADKITVMTVDPGFAGQPFIPEMLDKVAELKAWREREGLEYEIEVDGSCNQAT
HHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHH
YEKLMAAGADVFIVGTSGLFNHAENIDEAWRIMTAQILAAKSEVQPHAKTA
HHHHHHCCCCEEEEECCHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: D-allulose-6-phosphate [C]

Specific reaction: D-allulose-6-phosphate = fructose-6-phosphate [C]

General reaction: Isomerases; Racemases and Epimerases; Acting on Carbohydrates and Derivatives [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 9401019 [H]