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The map label for this gene is aaeR [H]

Identifier: 218691525

GI number: 218691525

Start: 3822052

End: 3822981

Strand: Direct

Name: aaeR [H]

Synonym: ECED1_3893

Alternate gene names: 218691525

Gene position: 3822052-3822981 (Clockwise)

Preceding gene: 218691520

Following gene: 218691534

Centisome position: 73.37

GC content: 52.26

Gene sequence:

>930_bases
ATGGAACGACTAAAACGCATGTCGGTGTTTGCCAAAGTAGTTGAATTTGGCTCTTTTACCGCCGCCGCCAGACAGCTACA
GATGAGCGTTTCGTCCATCAGTCAGACGGTGTCAAAACTGGAAGATGAGTTACAGATAAAGCTGTTAAACCGTAGTACAC
GCAGCATTGGCCTGACTGAAGCCGGCAGAATTTACTACCAGGGCTGCCGTCGGATGCTCCATGAAGTGCAGGATGTTCAT
GAGCAACTGTATGCCTTCAATAACACCCCCATCGGGACGCTGCGCATTGGCTGTTCTTCAACTATGGCACAAAATGTTCT
CGCCGGGCTGACGGCAAAAATGCTGAAAGAATACCCAGGTTTGAGTGTCAATCTGGTTACCGGAATTCCTGCCCCCGACC
TGATTGCCGACGGTCTGGATGTGGTGATCCGCGTCGGCGCGTTGCAAGATTCCAGCCTGTTTTCCCGCCGTCTGGGCGCG
ATGCCAATGGTGGTGTGCGCCGCAAAAAGCTATCTCACACAATACGGCATACCAGAAAAACCCGCCGATTTAAGTAGTCA
TTCATGGCTTGAATACAGCGTGCGACCCGACAATGAATTTGAACTGATCGCACCGGAAGGGATCTCGACTCGCCTGATCC
CGCAAGGGAGATTTGTGACTAATGATCCGATGACGCTGGTGCGCTGGCTGACGGCGGGTGCCGGGATCGCCTACGTGCCG
TTGATGTGGGTGATCAACGAGATCAATCGCGGGGAACTGGAGATCCTGCTGCCACGTTACCAGTCAGACCCACGCCCGGT
TTATGCGTTATATACCGAAAAAGATAAGCTGCCGCTGAAGGTACAAGTCGTGATCAACTCGCTAACGGATTATTTTGTTG
AGGTCGGTAAATTGTTTCAGGAGATGCACGGGCGCGGGAAAGAGAAGTAA

Upstream 100 bases:

>100_bases
AGAGCAACATTGCTGTAGATTGATATTTAATATATTAACGTAACTGTTATGCTGTTATCTATATTATGTGATCTAAATCA
CTTTTAAGTCAGAGTGAATA

Downstream 100 bases:

>100_bases
TTAATATTGTACTGTTACGTTGTACAAACCTGTGCCAACGGGTTCCCCTCACCCTAACCCCAGAGGGGCGAGGGGACCGT
TCGTACACGGAGAAGGATTA

Product: putative DNA-binding transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MERLKRMSVFAKVVEFGSFTAAARQLQMSVSSISQTVSKLEDELQIKLLNRSTRSIGLTEAGRIYYQGCRRMLHEVQDVH
EQLYAFNNTPIGTLRIGCSSTMAQNVLAGLTAKMLKEYPGLSVNLVTGIPAPDLIADGLDVVIRVGALQDSSLFSRRLGA
MPMVVCAAKSYLTQYGIPEKPADLSSHSWLEYSVRPDNEFELIAPEGISTRLIPQGRFVTNDPMTLVRWLTAGAGIAYVP
LMWVINEINRGELEILLPRYQSDPRPVYALYTEKDKLPLKVQVVINSLTDYFVEVGKLFQEMHGRGKEK

Sequences:

>Translated_309_residues
MERLKRMSVFAKVVEFGSFTAAARQLQMSVSSISQTVSKLEDELQIKLLNRSTRSIGLTEAGRIYYQGCRRMLHEVQDVH
EQLYAFNNTPIGTLRIGCSSTMAQNVLAGLTAKMLKEYPGLSVNLVTGIPAPDLIADGLDVVIRVGALQDSSLFSRRLGA
MPMVVCAAKSYLTQYGIPEKPADLSSHSWLEYSVRPDNEFELIAPEGISTRLIPQGRFVTNDPMTLVRWLTAGAGIAYVP
LMWVINEINRGELEILLPRYQSDPRPVYALYTEKDKLPLKVQVVINSLTDYFVEVGKLFQEMHGRGKEK
>Mature_309_residues
MERLKRMSVFAKVVEFGSFTAAARQLQMSVSSISQTVSKLEDELQIKLLNRSTRSIGLTEAGRIYYQGCRRMLHEVQDVH
EQLYAFNNTPIGTLRIGCSSTMAQNVLAGLTAKMLKEYPGLSVNLVTGIPAPDLIADGLDVVIRVGALQDSSLFSRRLGA
MPMVVCAAKSYLTQYGIPEKPADLSSHSWLEYSVRPDNEFELIAPEGISTRLIPQGRFVTNDPMTLVRWLTAGAGIAYVP
LMWVINEINRGELEILLPRYQSDPRPVYALYTEKDKLPLKVQVVINSLTDYFVEVGKLFQEMHGRGKEK

Specific function: Activates transcription of the aaeXAB operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789639, Length=309, Percent_Identity=99.6763754045307, Blast_Score=638, Evalue=0.0,
Organism=Escherichia coli, GI145693193, Length=299, Percent_Identity=30.7692307692308, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1786401, Length=288, Percent_Identity=31.25, Blast_Score=130, Evalue=8e-32,
Organism=Escherichia coli, GI1787128, Length=304, Percent_Identity=27.6315789473684, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI87081978, Length=293, Percent_Identity=29.3515358361775, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1787589, Length=274, Percent_Identity=28.1021897810219, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1789440, Length=290, Percent_Identity=27.2413793103448, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI157672245, Length=121, Percent_Identity=32.2314049586777, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1788481, Length=146, Percent_Identity=30.1369863013699, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1789173, Length=250, Percent_Identity=26, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788706, Length=141, Percent_Identity=30.4964539007092, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1787601, Length=126, Percent_Identity=23.8095238095238, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788297, Length=123, Percent_Identity=30.0813008130081, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1786508, Length=147, Percent_Identity=27.2108843537415, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34531; Mature: 34531

Theoretical pI: Translated: 8.41; Mature: 8.41

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERLKRMSVFAKVVEFGSFTAAARQLQMSVSSISQTVSKLEDELQIKLLNRSTRSIGLTE
CCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCH
AGRIYYQGCRRMLHEVQDVHEQLYAFNNTPIGTLRIGCSSTMAQNVLAGLTAKMLKEYPG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCC
LSVNLVTGIPAPDLIADGLDVVIRVGALQDSSLFSRRLGAMPMVVCAAKSYLTQYGIPEK
CEEEEEECCCCHHHHHCCHHHHEEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCC
PADLSSHSWLEYSVRPDNEFELIAPEGISTRLIPQGRFVTNDPMTLVRWLTAGAGIAYVP
CCCCCCCCEEEEEECCCCCEEEECCCCCCEEECCCCCEECCCHHHHHHHHHHCCCHHHHH
LMWVINEINRGELEILLPRYQSDPRPVYALYTEKDKLPLKVQVVINSLTDYFVEVGKLFQ
HHHHHHHCCCCCEEEEECCCCCCCCCEEEEEECCCCCCEEHHHHHHHHHHHHHHHHHHHH
EMHGRGKEK
HHHCCCCCC
>Mature Secondary Structure
MERLKRMSVFAKVVEFGSFTAAARQLQMSVSSISQTVSKLEDELQIKLLNRSTRSIGLTE
CCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCH
AGRIYYQGCRRMLHEVQDVHEQLYAFNNTPIGTLRIGCSSTMAQNVLAGLTAKMLKEYPG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCC
LSVNLVTGIPAPDLIADGLDVVIRVGALQDSSLFSRRLGAMPMVVCAAKSYLTQYGIPEK
CEEEEEECCCCHHHHHCCHHHHEEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCC
PADLSSHSWLEYSVRPDNEFELIAPEGISTRLIPQGRFVTNDPMTLVRWLTAGAGIAYVP
CCCCCCCCEEEEEECCCCCEEEECCCCCCEEECCCCCEECCCHHHHHHHHHHCCCHHHHH
LMWVINEINRGELEILLPRYQSDPRPVYALYTEKDKLPLKVQVVINSLTDYFVEVGKLFQ
HHHHHHHCCCCCEEEEECCCCCCCCCEEEEEECCCCCCEEHHHHHHHHHHHHHHHHHHHH
EMHGRGKEK
HHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]