Click here to switch to the map view.

The map label for this gene is agaA [H]

Identifier: 218691431

GI number: 218691431

Start: 3728543

End: 3729697

Strand: Direct

Name: agaA [H]

Synonym: ECED1_3799

Alternate gene names: 218691431

Gene position: 3728543-3729697 (Clockwise)

Preceding gene: 218691430

Following gene: 218691432

Centisome position: 71.57

GC content: 57.58

Gene sequence:

>1155_bases
ATGTCCGGTCGAGGAAGGAATATGACACACGTTCTGCGCGCCAGAAGGCTGCTGACTGAAGAGGGATGGCTCGATGACCA
TCAGTTGCGTATTGCTGACGGTGTAATCGCAGCAATCGAACCGATTCCAGTGGGCGTGACTGAACGCGATGTGGAACTGC
TCTGCCCCGCTTACATCGACACCCATGTACACGGTGGTGCGGGCGTTGATGTAATGGATGACGCGCCGGATGCGCTCGAC
AAGCTGGCAATGCACAAGGCACGCGAAGGTGTCGGCAGTTGGTTACCGACCACCGTAACCGCGCCGCTTAATACCATTCA
TGCGACGCTGAAACGTATTGCTCTACGCTGCCAGCGTGGCGGACCTGGTGCACAAGTGCTGGGGAGTTATCTCGAAGGAC
CGTACTTCACGCCGCAGAATAAAGGCACGCATCCGCCGGAGCTGTTTCGCGAGCTTGAAATTGCCGAGCTGGATCAATTG
ATTGCCGTTTCTCAGCATACCTTGCGCGTGGTAGCGCTGGCACCAGAAAAAGAAGGGGCATTGCAGGCCATCCGCCATCT
TAAACAGCAAAACGTACGGGTGATGCTGGGGCATAGCGCGGCGACCTGGCAACAAACCCGTGCCGCGTTTGATGCTGGTG
CCGACGGCCTGGTGCATTGCTATAACGGGATGACAGGTTTACATCACCGCGAACCGGGAATGGTTGGCGCGGGATTAACA
GACAAGCGCGCCTGGCTGGAACTGATAGCCGATGGTCATCATGTACATCCGGCGGCAATGTCGCTCTGTTGTTGCTGTGC
GAAAGAGAGGATCGTACTGATCACCGACGCGATGCAGGCAGCCGGGATGCCGGATGGTCACTATACGTTATGTGGTGAAG
AAGTGCAGATGCGCGGTGGCGTTGTCCGTACCGCGTCCGGTGGGCTGGCGGGCAGTACGCTGTCTGTCGATGCGGCAGTG
CGCAACATGGTCGAGTTGACGGGCGTAACGCCTGCGGAAGCCATCCATATGGCGTCGCTGCATCCGGCGCGAATGCTGGG
TGTTGATGGTGTTCTGGGATCGCTTAAACCGGGCAAACGCGCCAGCGTCGTTGCGCTGGATAGCGGGCTGCATGTGCAAC
AAATCTGGATTCAGGGTCAATTAGCTTCGTTTTGA

Upstream 100 bases:

>100_bases
GCGAAGGGTTAAGCGGTGAAGAGTTCCGTGTGCAGGCGCTGGAGTGTGGACACCGTGGGCTAACCAGTCTGGTGGACGAA
CTTGGTCGCTGCCATGAGGA

Downstream 100 bases:

>100_bases
TGGTTTGCTCCTTTATTAGGCCTTCACTTCCCCCGTAAGGCCTTTCTTTTTCTTTCGTTTTGATCTGTGCAGCGGTGTCG
GATGCGACGCTAATGCGTCT

Product: N-acetylglucosamine-6-phosphate deacetylase

Products: D-Galactosamine 6-Phosphate; Acetate. [C]

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 383

Protein sequence:

>384_residues
MSGRGRNMTHVLRARRLLTEEGWLDDHQLRIADGVIAAIEPIPVGVTERDVELLCPAYIDTHVHGGAGVDVMDDAPDALD
KLAMHKAREGVGSWLPTTVTAPLNTIHATLKRIALRCQRGGPGAQVLGSYLEGPYFTPQNKGTHPPELFRELEIAELDQL
IAVSQHTLRVVALAPEKEGALQAIRHLKQQNVRVMLGHSAATWQQTRAAFDAGADGLVHCYNGMTGLHHREPGMVGAGLT
DKRAWLELIADGHHVHPAAMSLCCCCAKERIVLITDAMQAAGMPDGHYTLCGEEVQMRGGVVRTASGGLAGSTLSVDAAV
RNMVELTGVTPAEAIHMASLHPARMLGVDGVLGSLKPGKRASVVALDSGLHVQQIWIQGQLASF

Sequences:

>Translated_384_residues
MSGRGRNMTHVLRARRLLTEEGWLDDHQLRIADGVIAAIEPIPVGVTERDVELLCPAYIDTHVHGGAGVDVMDDAPDALD
KLAMHKAREGVGSWLPTTVTAPLNTIHATLKRIALRCQRGGPGAQVLGSYLEGPYFTPQNKGTHPPELFRELEIAELDQL
IAVSQHTLRVVALAPEKEGALQAIRHLKQQNVRVMLGHSAATWQQTRAAFDAGADGLVHCYNGMTGLHHREPGMVGAGLT
DKRAWLELIADGHHVHPAAMSLCCCCAKERIVLITDAMQAAGMPDGHYTLCGEEVQMRGGVVRTASGGLAGSTLSVDAAV
RNMVELTGVTPAEAIHMASLHPARMLGVDGVLGSLKPGKRASVVALDSGLHVQQIWIQGQLASF
>Mature_383_residues
SGRGRNMTHVLRARRLLTEEGWLDDHQLRIADGVIAAIEPIPVGVTERDVELLCPAYIDTHVHGGAGVDVMDDAPDALDK
LAMHKAREGVGSWLPTTVTAPLNTIHATLKRIALRCQRGGPGAQVLGSYLEGPYFTPQNKGTHPPELFRELEIAELDQLI
AVSQHTLRVVALAPEKEGALQAIRHLKQQNVRVMLGHSAATWQQTRAAFDAGADGLVHCYNGMTGLHHREPGMVGAGLTD
KRAWLELIADGHHVHPAAMSLCCCCAKERIVLITDAMQAAGMPDGHYTLCGEEVQMRGGVVRTASGGLAGSTLSVDAAVR
NMVELTGVTPAEAIHMASLHPARMLGVDGVLGSLKPGKRASVVALDSGLHVQQIWIQGQLASF

Specific function: N-acetylgalactosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=415, Percent_Identity=32.7710843373494, Blast_Score=189, Evalue=4e-48,
Organism=Homo sapiens, GI224922791, Length=415, Percent_Identity=32.5301204819277, Blast_Score=184, Evalue=8e-47,
Organism=Escherichia coli, GI1786892, Length=380, Percent_Identity=31.3157894736842, Blast_Score=183, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI17553768, Length=387, Percent_Identity=29.9741602067183, Blast_Score=156, Evalue=2e-38,
Organism=Drosophila melanogaster, GI19920392, Length=389, Percent_Identity=30.5912596401028, Blast_Score=178, Evalue=6e-45,
Organism=Drosophila melanogaster, GI281361140, Length=402, Percent_Identity=30.3482587064677, Blast_Score=173, Evalue=1e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: 3.5.1.- [C]

Molecular weight: Translated: 41072; Mature: 40941

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGRGRNMTHVLRARRLLTEEGWLDDHQLRIADGVIAAIEPIPVGVTERDVELLCPAYID
CCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCEEEEECCCCCCCCCCCHHHHCHHHHH
THVHGGAGVDVMDDAPDALDKLAMHKAREGVGSWLPTTVTAPLNTIHATLKRIALRCQRG
HCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
GPGAQVLGSYLEGPYFTPQNKGTHPPELFRELEIAELDQLIAVSQHTLRVVALAPEKEGA
CCHHHHHHHHHCCCEECCCCCCCCCHHHHHHCCHHHHHHHHHHHHCEEEEEEECCCCCHH
LQAIRHLKQQNVRVMLGHSAATWQQTRAAFDAGADGLVHCYNGMTGLHHREPGMVGAGLT
HHHHHHHHHCCCEEEECCCHHHHHHHHHHHHCCCCCCEEHHCCCCCCCCCCCCCEECCCC
DKRAWLELIADGHHVHPAAMSLCCCCAKERIVLITDAMQAAGMPDGHYTLCGEEVQMRGG
HHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEEECHHHCCCCCCCEEECCHHHHHCCC
VVRTASGGLAGSTLSVDAAVRNMVELTGVTPAEAIHMASLHPARMLGVDGVLGSLKPGKR
EEEECCCCCCCCEEEHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHCCCHHHCCCCCCCC
ASVVALDSGLHVQQIWIQGQLASF
EEEEEECCCCEEEEEEEECCCCCC
>Mature Secondary Structure 
SGRGRNMTHVLRARRLLTEEGWLDDHQLRIADGVIAAIEPIPVGVTERDVELLCPAYID
CCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCEEEEECCCCCCCCCCCHHHHCHHHHH
THVHGGAGVDVMDDAPDALDKLAMHKAREGVGSWLPTTVTAPLNTIHATLKRIALRCQRG
HCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
GPGAQVLGSYLEGPYFTPQNKGTHPPELFRELEIAELDQLIAVSQHTLRVVALAPEKEGA
CCHHHHHHHHHCCCEECCCCCCCCCHHHHHHCCHHHHHHHHHHHHCEEEEEEECCCCCHH
LQAIRHLKQQNVRVMLGHSAATWQQTRAAFDAGADGLVHCYNGMTGLHHREPGMVGAGLT
HHHHHHHHHCCCEEEECCCHHHHHHHHHHHHCCCCCCEEHHCCCCCCCCCCCCCEECCCC
DKRAWLELIADGHHVHPAAMSLCCCCAKERIVLITDAMQAAGMPDGHYTLCGEEVQMRGG
HHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEEECHHHCCCCCCCEEECCHHHHHCCC
VVRTASGGLAGSTLSVDAAVRNMVELTGVTPAEAIHMASLHPARMLGVDGVLGSLKPGKR
EEEECCCCCCCCEEEHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHCCCHHHCCCCCCCC
ASVVALDSGLHVQQIWIQGQLASF
EEEEEECCCCEEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N-Acetyl-D-Galactosamine 6-Phosphate; H2O [C]

Specific reaction: N-Acetyl-D-Galactosamine 6-Phosphate + H2O = D-Galactosamine 6-Phosphate + Acetate. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503; 8932697 [H]