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The map label for this gene is ssb [H]

Identifier: 218691232

GI number: 218691232

Start: 3509261

End: 3509818

Strand: Reverse

Name: ssb [H]

Synonym: ECED1_3589

Alternate gene names: 218691232

Gene position: 3509818-3509261 (Counterclockwise)

Preceding gene: 218691233

Following gene: 218691231

Centisome position: 67.37

GC content: 52.51

Gene sequence:

>558_bases
ATGGCTTCGCGTGGTGTAAACAAAGTCATCCTGCTTGGGCATCTGGGACAGGATCCGGAGGTCAGGTACTTTCCTAACGG
TGGTGGTGCAGTGGTGAATTTGTCACTGGCGACCAGTGATACCTGGAAGGATAAACAGAGCGGTGAAATGAAGGAAGTGA
CCGAATGGCACCGCATTGTTATTTATGGAAAACTGGCAGAAATCGCCGGAGAGTACCTTCGTAAGGGCTCTAAGGTTTAT
ATCGAAGGTCAGCTGAAAACCCGTAAGTGGTTTGACCAGCAGAACGGTGTGGACCGTTATTCAACTGAGGTTGTTGTGGG
AGTGAATGGTGTCATGCAGATGCTGGGTTCGCTGCGTCAGCAGGGCACTGCCGGTAATGGTGCTTCTGCACCTGCACAAG
GGGGCTGGGGACAGCCGCCGAAGACGGCCGGACAGGCTGGTCGTGCACCCCAGACAACATCAACGGGTAATGGTGCACCA
CCAATGGACTTTGACGATGATATTCCCTTTATGGGGCTCGGGTATGGCATGGAACGACGAATTATTCATGCCATGTAA

Upstream 100 bases:

>100_bases
CCGTGAATCTGAAGAGTATTTCAAAAAACATGATCAGGCTGAGCAGGCGCTGAAAAATGGCACCTGGAGACAGCGTTGTG
GCTGGTAATGAGGGGGGAGT

Downstream 100 bases:

>100_bases
CATCAACCATGGGGCGTTACGCCCCACTTTTTTATCTGGAGGTTCCGTGAGTGAAAAAGTTAATAAAACCAGCCTGATAC
ATGATGCGGCGTTCAGGAAG

Product: Single-stranded DNA-binding protein

Products: NA

Alternate protein names: SSB; Helix-destabilizing protein [H]

Number of amino acids: Translated: 185; Mature: 184

Protein sequence:

>185_residues
MASRGVNKVILLGHLGQDPEVRYFPNGGGAVVNLSLATSDTWKDKQSGEMKEVTEWHRIVIYGKLAEIAGEYLRKGSKVY
IEGQLKTRKWFDQQNGVDRYSTEVVVGVNGVMQMLGSLRQQGTAGNGASAPAQGGWGQPPKTAGQAGRAPQTTSTGNGAP
PMDFDDDIPFMGLGYGMERRIIHAM

Sequences:

>Translated_185_residues
MASRGVNKVILLGHLGQDPEVRYFPNGGGAVVNLSLATSDTWKDKQSGEMKEVTEWHRIVIYGKLAEIAGEYLRKGSKVY
IEGQLKTRKWFDQQNGVDRYSTEVVVGVNGVMQMLGSLRQQGTAGNGASAPAQGGWGQPPKTAGQAGRAPQTTSTGNGAP
PMDFDDDIPFMGLGYGMERRIIHAM
>Mature_184_residues
ASRGVNKVILLGHLGQDPEVRYFPNGGGAVVNLSLATSDTWKDKQSGEMKEVTEWHRIVIYGKLAEIAGEYLRKGSKVYI
EGQLKTRKWFDQQNGVDRYSTEVVVGVNGVMQMLGSLRQQGTAGNGASAPAQGGWGQPPKTAGQAGRAPQTTSTGNGAPP
MDFDDDIPFMGLGYGMERRIIHAM

Specific function: This protein is essential for replication of the chromosome. It is also involved in DNA recombination and repair [H]

COG id: COG0629

COG function: function code L; Single-stranded DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SSB domain [H]

Homologues:

Organism=Homo sapiens, GI4507231, Length=111, Percent_Identity=35.1351351351351, Blast_Score=70, Evalue=9e-13,
Organism=Escherichia coli, GI1790494, Length=185, Percent_Identity=60.5405405405405, Blast_Score=196, Evalue=9e-52,

Paralogues:

None

Copy number: 1622 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000424
- InterPro:   IPR011344 [H]

Pfam domain/function: PF00436 SSB [H]

EC number: NA

Molecular weight: Translated: 19969; Mature: 19838

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: PS50935 SSB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASRGVNKVILLGHLGQDPEVRYFPNGGGAVVNLSLATSDTWKDKQSGEMKEVTEWHRIV
CCCCCCCEEEEEEECCCCCCEEEEECCCCEEEEEEEECCCCCCCCCCCCHHHHHHHEEEE
IYGKLAEIAGEYLRKGSKVYIEGQLKTRKWFDQQNGVDRYSTEVVVGVNGVMQMLGSLRQ
EEEHHHHHHHHHHHCCCEEEEEECCCHHHHHHCCCCCCCCCCEEEEEHHHHHHHHHHHHH
QGTAGNGASAPAQGGWGQPPKTAGQAGRAPQTTSTGNGAPPMDFDDDIPFMGLGYGMERR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCHHH
IIHAM
HEECC
>Mature Secondary Structure 
ASRGVNKVILLGHLGQDPEVRYFPNGGGAVVNLSLATSDTWKDKQSGEMKEVTEWHRIV
CCCCCCEEEEEEECCCCCCEEEEECCCCEEEEEEEECCCCCCCCCCCCHHHHHHHEEEE
IYGKLAEIAGEYLRKGSKVYIEGQLKTRKWFDQQNGVDRYSTEVVVGVNGVMQMLGSLRQ
EEEHHHHHHHHHHHCCCEEEEEECCCHHHHHHCCCCCCCCCCEEEEEHHHHHHHHHHHHH
QGTAGNGASAPAQGGWGQPPKTAGQAGRAPQTTSTGNGAPPMDFDDDIPFMGLGYGMERR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCHHH
IIHAM
HEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9973335; 10952301 [H]