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The map label for this gene is irgA [H]

Identifier: 218691207

GI number: 218691207

Start: 3485005

End: 3487095

Strand: Reverse

Name: irgA [H]

Synonym: ECED1_3560

Alternate gene names: 218691207

Gene position: 3487095-3485005 (Counterclockwise)

Preceding gene: 218691208

Following gene: 218691206

Centisome position: 66.94

GC content: 51.65

Gene sequence:

>2091_bases
ATGCGAATAACCACTCTGGCTTCTGTCATCATTCCCTGCCTCGGATTCTCAGCCAGCAGCATGGCTGCTGCAGAGGATGT
GATGATTGTCTCGGCATCCGGCTATGAGAAAAAACTGACTAACGCAGCCGCCAGTGTCTCTGTGATCAGCCAGGAGGAAT
TGCAGTCCAGGCAGTACCACGATCTGGCGGAGGCTCTGAGATCTGTCGAGGGTGTGGATGTTGAAAGTGGTACGGGTAAA
ACCGGTGGGCTGGAAATCAGCATCCGTGGAATGCCTGCCAGTTACACGCTGATACTGATTGATGGTGTTCGTCAGGGCGG
GAGCAGTGACGTGACTCCCAACGGTTTTTCTGCCATGAATACCGGGTTCATGCCTCCTCTGGCCGCCATTGAGCGTATTG
AGGTTATCAGGGGGCCGATGTCCACACTGTATGGCTCTGATGCGATGGGCGGTGTGGTGAATATCATTACCAGAAAGAAT
GCAGACAAATGGCTCTCTTCCGTCAATGCAGGGCTGAATCTGCAGGAAAGCAACAAATGGGGTAACAGCAGCCAGTTTAA
TTTCTGGACCAGTGGTCCCCTTGTGGATGATTCTGTCAGTCTGCAGGTCCGGGGCAGCACACAGCAGCGTCAGGGCTCAT
CGGTCACATCACTGAGCGACACAGCAGCCACGCGTATTCCTTATCCCACGGAGTCACAGAATTATAATATTGGTGCGCGT
CTTGACTGGAAAGCCACGGAGCAGGATGTACTCTGGTTTGATATGGATACCACCCGGCAGCGTTATGATAACCGGGACGG
GCAGCTGGGGAGTCTGACCGGGGGATATGACCGTACCCTGCGCTATGAGCGAAACAAAATTTCAGCTGGCTATGATCATT
CTTTCACCTTCGGTACCTGGAAATCGTATCTGAACTGGAACGAGACGGAAAATAAAGGTCGTGAACTTGTACAAAGTGTA
CTGAAGCGCGACAAATGGGAGCTTGCCGGTCAGCCGCGGGAGCTTAAGGAATCTAACTTTATCCTGAATTCATTACTGCT
TACCCCTCTGGGAGAATCTCATCTGGTTACGGTGGGGGGCGAGTATCAGAGTTCGTCCATGAAAGACGGGGTTGTCCTTG
CCAGCACAGGTGAAACTTTCCGGCAGAAAAGCTGGTCGGTATTTGCGGAGGATGAGTGGCATCTTACGGATGCACTTGCG
CTGACTGCGGGCAGCCGCTATGAACATCATGAGCAATTCGGGGGACACTTCAGTCCGCGTGCATATCTGGTCTGGGATGT
GGCAGATGCCTGGACGCTGAAAGGCGGTGTGACCACGGGATATAAAGCCCCCACCATGGGACAGTTACATAAGGGGATCA
GCGGTGTATCCGGGCAGGGACGTACTAATCTACTCGGTAACCCCGAACTGAAGCCGGAAGAGAGTGTAAGTTATGAGGCG
GGGGTATATTACGATAACCTCTCCGGTCTGAATGCCAATATAACAGGCTTTATAACAGACTTCTCCAACAAGATTGTCTC
TTATTCCATTGATGATAACACCAATAGCTATACAAACAGCGGAAAGGCCCGCTTGCATGGTGTGGAATTTGCCGGCACAT
TGCCGCTGTGGTCAGAGGATGTCACTCTGTCGTTGAATTACACCTGGACCCGAAGTGAACAACGTGATGGTGATAACAAA
GGTGCACCGCTGAGCTATACTCCTGAACACATGGTGAATGCGAAACTGAACTGGCAGATCACCGAAGAAGTTGCGTCATG
GCTGGGGGCTCGCTATCGCGATAAAACTCCACGCTTCACCCGGAATTATTCGTCGCTGAGCGCTGTACAGAAGAAAGTGT
ATGATGAGAAAGGAGAATATCTGAAAGCCTGGACGGTGGTGGATGCAGGTCTGTCGTGGAAGGTGACGGATGCCCTGACG
CTGAATGCTGCGGTGAATAACCTGCTCAACAAGGATTACAGTGACGTGAGCCTGTACAGTGCCGGTAAGAGTACGCTTTA
TGCCGGTGATTACTTCCAGACGGGATCATCAACAACGGGCTATGTGATACCTGAGCGAAATTACTGGATGTCACTGAACT
ATCAGTTCTGA

Upstream 100 bases:

>100_bases
ATGAATCTTCAGTTTTTGTAAAAAGTAAATATAAATTATTCTCATTATTATTTGTATTTGTGTATTGTCTTGCCGGTTAA
TATGATCGGAGATTATTAAT

Downstream 100 bases:

>100_bases
TAATCATAAAACCGTATCACTGACGGTAGCATACGTTGCCACTGCAGCTCCTGGATGTTCAGTGGCTACGTTATATGATT
CCCGGTGTCTGATTTCTGTT

Product: bifunctional enterobactin receptor/adhesin protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 696; Mature: 696

Protein sequence:

>696_residues
MRITTLASVIIPCLGFSASSMAAAEDVMIVSASGYEKKLTNAAASVSVISQEELQSRQYHDLAEALRSVEGVDVESGTGK
TGGLEISIRGMPASYTLILIDGVRQGGSSDVTPNGFSAMNTGFMPPLAAIERIEVIRGPMSTLYGSDAMGGVVNIITRKN
ADKWLSSVNAGLNLQESNKWGNSSQFNFWTSGPLVDDSVSLQVRGSTQQRQGSSVTSLSDTAATRIPYPTESQNYNIGAR
LDWKATEQDVLWFDMDTTRQRYDNRDGQLGSLTGGYDRTLRYERNKISAGYDHSFTFGTWKSYLNWNETENKGRELVQSV
LKRDKWELAGQPRELKESNFILNSLLLTPLGESHLVTVGGEYQSSSMKDGVVLASTGETFRQKSWSVFAEDEWHLTDALA
LTAGSRYEHHEQFGGHFSPRAYLVWDVADAWTLKGGVTTGYKAPTMGQLHKGISGVSGQGRTNLLGNPELKPEESVSYEA
GVYYDNLSGLNANITGFITDFSNKIVSYSIDDNTNSYTNSGKARLHGVEFAGTLPLWSEDVTLSLNYTWTRSEQRDGDNK
GAPLSYTPEHMVNAKLNWQITEEVASWLGARYRDKTPRFTRNYSSLSAVQKKVYDEKGEYLKAWTVVDAGLSWKVTDALT
LNAAVNNLLNKDYSDVSLYSAGKSTLYAGDYFQTGSSTTGYVIPERNYWMSLNYQF

Sequences:

>Translated_696_residues
MRITTLASVIIPCLGFSASSMAAAEDVMIVSASGYEKKLTNAAASVSVISQEELQSRQYHDLAEALRSVEGVDVESGTGK
TGGLEISIRGMPASYTLILIDGVRQGGSSDVTPNGFSAMNTGFMPPLAAIERIEVIRGPMSTLYGSDAMGGVVNIITRKN
ADKWLSSVNAGLNLQESNKWGNSSQFNFWTSGPLVDDSVSLQVRGSTQQRQGSSVTSLSDTAATRIPYPTESQNYNIGAR
LDWKATEQDVLWFDMDTTRQRYDNRDGQLGSLTGGYDRTLRYERNKISAGYDHSFTFGTWKSYLNWNETENKGRELVQSV
LKRDKWELAGQPRELKESNFILNSLLLTPLGESHLVTVGGEYQSSSMKDGVVLASTGETFRQKSWSVFAEDEWHLTDALA
LTAGSRYEHHEQFGGHFSPRAYLVWDVADAWTLKGGVTTGYKAPTMGQLHKGISGVSGQGRTNLLGNPELKPEESVSYEA
GVYYDNLSGLNANITGFITDFSNKIVSYSIDDNTNSYTNSGKARLHGVEFAGTLPLWSEDVTLSLNYTWTRSEQRDGDNK
GAPLSYTPEHMVNAKLNWQITEEVASWLGARYRDKTPRFTRNYSSLSAVQKKVYDEKGEYLKAWTVVDAGLSWKVTDALT
LNAAVNNLLNKDYSDVSLYSAGKSTLYAGDYFQTGSSTTGYVIPERNYWMSLNYQF
>Mature_696_residues
MRITTLASVIIPCLGFSASSMAAAEDVMIVSASGYEKKLTNAAASVSVISQEELQSRQYHDLAEALRSVEGVDVESGTGK
TGGLEISIRGMPASYTLILIDGVRQGGSSDVTPNGFSAMNTGFMPPLAAIERIEVIRGPMSTLYGSDAMGGVVNIITRKN
ADKWLSSVNAGLNLQESNKWGNSSQFNFWTSGPLVDDSVSLQVRGSTQQRQGSSVTSLSDTAATRIPYPTESQNYNIGAR
LDWKATEQDVLWFDMDTTRQRYDNRDGQLGSLTGGYDRTLRYERNKISAGYDHSFTFGTWKSYLNWNETENKGRELVQSV
LKRDKWELAGQPRELKESNFILNSLLLTPLGESHLVTVGGEYQSSSMKDGVVLASTGETFRQKSWSVFAEDEWHLTDALA
LTAGSRYEHHEQFGGHFSPRAYLVWDVADAWTLKGGVTTGYKAPTMGQLHKGISGVSGQGRTNLLGNPELKPEESVSYEA
GVYYDNLSGLNANITGFITDFSNKIVSYSIDDNTNSYTNSGKARLHGVEFAGTLPLWSEDVTLSLNYTWTRSEQRDGDNK
GAPLSYTPEHMVNAKLNWQITEEVASWLGARYRDKTPRFTRNYSSLSAVQKKVYDEKGEYLKAWTVVDAGLSWKVTDALT
LNAAVNNLLNKDYSDVSLYSAGKSTLYAGDYFQTGSSTTGYVIPERNYWMSLNYQF

Specific function: Involved in the initial step of iron uptake by binding ferric vibriobactin, an iron chelatin siderophore that allows V.cholerae to extract iron from the environment [H]

COG id: COG4771

COG function: function code P; Outer membrane receptor for ferrienterochelin and colicins

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=683, Percent_Identity=32.5036603221083, Blast_Score=286, Evalue=3e-78,
Organism=Escherichia coli, GI1786798, Length=749, Percent_Identity=28.3044058744993, Blast_Score=192, Evalue=8e-50,
Organism=Escherichia coli, GI1790405, Length=695, Percent_Identity=25.6115107913669, Blast_Score=163, Evalue=3e-41,
Organism=Escherichia coli, GI1787723, Length=162, Percent_Identity=32.7160493827161, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 76794; Mature: 76794

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRITTLASVIIPCLGFSASSMAAAEDVMIVSASGYEKKLTNAAASVSVISQEELQSRQYH
CCHHHHHHHHHHHCCCCCHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
DLAEALRSVEGVDVESGTGKTGGLEISIRGMPASYTLILIDGVRQGGSSDVTPNGFSAMN
HHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCEEEEEEEECCCCCCCCCCCCCCCCCCC
TGFMPPLAAIERIEVIRGPMSTLYGSDAMGGVVNIITRKNADKWLSSVNAGLNLQESNKW
CCCCCHHHHHHHHHHHHCCHHHHCCCCCCCCEEEEEECCCHHHHHHHHHCCCEEECCCCC
GNSSQFNFWTSGPLVDDSVSLQVRGSTQQRQGSSVTSLSDTAATRIPYPTESQNYNIGAR
CCCCCEEEEECCCEECCCEEEEEECCCHHCCCCCCCCCCCHHHCCCCCCCCCCCCCCCEE
LDWKATEQDVLWFDMDTTRQRYDNRDGQLGSLTGGYDRTLRYERNKISAGYDHSFTFGTW
EECCCCCCCEEEEECCHHHHHHCCCCCCCCCCCCCCHHEEEEECCCCCCCCCCCEEHHHH
KSYLNWNETENKGRELVQSVLKRDKWELAGQPRELKESNFILNSLLLTPLGESHLVTVGG
HHHCCCCCCHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECC
EYQSSSMKDGVVLASTGETFRQKSWSVFAEDEWHLTDALALTAGSRYEHHEQFGGHFSPR
CCCCCCCCCCEEEEECCHHHHCCCCEEEECCCCEEEHEEEECCCCCCHHHHHHCCCCCCC
AYLVWDVADAWTLKGGVTTGYKAPTMGQLHKGISGVSGQGRTNLLGNPELKPEESVSYEA
EEEEEECCCCEEECCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEC
GVYYDNLSGLNANITGFITDFSNKIVSYSIDDNTNSYTNSGKARLHGVEFAGTLPLWSED
CEEEECCCCCCCCEEEEEEECCCCEEEEEECCCCCCCCCCCCEEEEEEEEECCCCCCCCC
VTLSLNYTWTRSEQRDGDNKGAPLSYTPEHMVNAKLNWQITEEVASWLGARYRDKTPRFT
EEEEEEEEEECCCCCCCCCCCCCCCCCHHHHCCCEEEEEEHHHHHHHHCCCCCCCCCCHH
RNYSSLSAVQKKVYDEKGEYLKAWTVVDAGLSWKVTDALTLNAAVNNLLNKDYSDVSLYS
CCHHHHHHHHHHHHHCCCCEEEEEEEEECCCCEEEEEEEEHHHHHHHHHCCCCCCEEEEE
AGKSTLYAGDYFQTGSSTTGYVIPERNYWMSLNYQF
CCCCEEEECCEEECCCCCCEEEEECCCEEEEEEECC
>Mature Secondary Structure
MRITTLASVIIPCLGFSASSMAAAEDVMIVSASGYEKKLTNAAASVSVISQEELQSRQYH
CCHHHHHHHHHHHCCCCCHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
DLAEALRSVEGVDVESGTGKTGGLEISIRGMPASYTLILIDGVRQGGSSDVTPNGFSAMN
HHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCEEEEEEEECCCCCCCCCCCCCCCCCCC
TGFMPPLAAIERIEVIRGPMSTLYGSDAMGGVVNIITRKNADKWLSSVNAGLNLQESNKW
CCCCCHHHHHHHHHHHHCCHHHHCCCCCCCCEEEEEECCCHHHHHHHHHCCCEEECCCCC
GNSSQFNFWTSGPLVDDSVSLQVRGSTQQRQGSSVTSLSDTAATRIPYPTESQNYNIGAR
CCCCCEEEEECCCEECCCEEEEEECCCHHCCCCCCCCCCCHHHCCCCCCCCCCCCCCCEE
LDWKATEQDVLWFDMDTTRQRYDNRDGQLGSLTGGYDRTLRYERNKISAGYDHSFTFGTW
EECCCCCCCEEEEECCHHHHHHCCCCCCCCCCCCCCHHEEEEECCCCCCCCCCCEEHHHH
KSYLNWNETENKGRELVQSVLKRDKWELAGQPRELKESNFILNSLLLTPLGESHLVTVGG
HHHCCCCCCHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECC
EYQSSSMKDGVVLASTGETFRQKSWSVFAEDEWHLTDALALTAGSRYEHHEQFGGHFSPR
CCCCCCCCCCEEEEECCHHHHCCCCEEEECCCCEEEHEEEECCCCCCHHHHHHCCCCCCC
AYLVWDVADAWTLKGGVTTGYKAPTMGQLHKGISGVSGQGRTNLLGNPELKPEESVSYEA
EEEEEECCCCEEECCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEC
GVYYDNLSGLNANITGFITDFSNKIVSYSIDDNTNSYTNSGKARLHGVEFAGTLPLWSED
CEEEECCCCCCCCEEEEEEECCCCEEEEEECCCCCCCCCCCCEEEEEEEEECCCCCCCCC
VTLSLNYTWTRSEQRDGDNKGAPLSYTPEHMVNAKLNWQITEEVASWLGARYRDKTPRFT
EEEEEEEEEECCCCCCCCCCCCCCCCCHHHHCCCEEEEEEHHHHHHHHCCCCCCCCCCHH
RNYSSLSAVQKKVYDEKGEYLKAWTVVDAGLSWKVTDALTLNAAVNNLLNKDYSDVSLYS
CCHHHHHHHHHHHHHCCCCEEEEEEEEECCCCEEEEEEEEHHHHHHHHHCCCCCCEEEEE
AGKSTLYAGDYFQTGSSTTGYVIPERNYWMSLNYQF
CCCCEEEECCEEECCCCCCEEEEECCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1406279; 2174861 [H]