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The map label for this gene is fucK [H]

Identifier: 218690926

GI number: 218690926

Start: 3194879

End: 3196327

Strand: Direct

Name: fucK [H]

Synonym: ECED1_3256

Alternate gene names: 218690926

Gene position: 3194879-3196327 (Clockwise)

Preceding gene: 218690925

Following gene: 218690927

Centisome position: 61.33

GC content: 51.0

Gene sequence:

>1449_bases
ATGTTATCCGGCTATATTGCAGGAGCGATTATGAAACAAGAAGTTATCCTGGTACTCGACTGTGGCGCGACCAATGTCAG
GGCCATCGCGGTTAATCGGCAGGGAAAAATTGTTGCCCGCGCCTCAACGCCTAATGCCAGCGATATCGCGATGGAAAACA
ACACCTGGCACCAGTGGTCTTTAGACGCCATTTTGCAACGCTTTGCTGATTGCTGTCGGCAAATCAATAGTGAACTGACT
GATTGCCACATCCGCGGTATCGCCGTCACCACCTTTGGTGTGGATGGCGCTCTGGTAGATAAGCAAGGCAATCTGCTCTA
TCCGATCATTAGCTGGAAATGTCCGCGAACAGCCGCGGTAATGGACAATATTGAACGGTTGATCTCCGAACAGCAGTTGC
AGGCTATTTCTGGAGTCGGAGCCTTTAGTTTCAATACGTTATATAAGTTGGTGTGGTTGAAAGAAAATCATCCACAACTG
CTGGAACGCGCGCACGCCTGGCTCTTTATTTCGTCGCTGATTAACCACCGTTTAACCGGCGAATTCACTACTGATATCAC
GATGGCCGGAACCAGCCAGATGCTGGATATCCAGCAACGCGATTTCAGTCCGCAAATTTTACAAGCCACCGGTATTCCAC
GCCGACTCTTCCCTCGTCTGGTGGAAGCGGGTGAACAGATTGGTACGCTACAGAACAGCGCCGCAGCAATGCTCGGCTTA
CCCGTTGGCATACCGGTGATTTCCGCAGGTCACGATACCCAGTTCGCCCTTTTTGGCGCTGGTGCCGAACAAAATGAACC
CGTGCTCTCTTCCGGTACATGGGAAATTTTAATGGTCCGCAGCGCCCAGGTTGATACTTCGCTGTTAAGTCAGTACGCCG
GTTCGACCTGCGAACTGGATAGTCAGGCAGGGTTGTATAACCCAGGTATGCAATGGCTGGCATCCGGCGTGCTGGAGTGG
GTGAGAAAACTGTTCTGGACGGCAGAAACTCCCTGGCAAATGTTGATTGAAGAAGCTCGTCTGATCGCGCCTGGCGCAGA
TGGAGTGAAAATGCAGTGTGATTTATTGTCGTGTCAGAACGCTGGCTGGCAAGGCGTAACGCTTAATACCACGCGGGGGC
ATTTCTATCGCGCGGCGCTGGAAGGGTTAACTGCGCAATTACAGCGCAATCTACAGATGCTGGAAAAAATCGGGCACTTT
AAGGCCTCTGAATTATTGTTAGTCGGTGGAGGAAGTCGCAACACATTGTGGAATCAGATTAAAGCCAATATGCTTGATAT
TCCGGTAAAAGTTCTCGACGACGCCGAAACGACCGTCGCAGGAGCTGCGCTGTTCGGTTGGTATGGCGTAGGGGAATTTA
ACAGCCCGGAGGAAGCTCGCGCGCAGATTCATTATCAGTACCGTTATTTCTACCCGCAAACTGAACCTGAATTTATAGAG
GAAGTGTGA

Upstream 100 bases:

>100_bases
CGGCCCGTTGTACAAGCGTTAATACATTACTCCCTGATGTGATGCCCGGTCGCTCCGGCTACCGGGCCTGAACAAGCAAG
AGTGGTTAGCCGGATAAGCA

Downstream 100 bases:

>100_bases
AATGCTGAAAACAATTTCGCCGTTAATTTCTCCCGAACTATTGAAAGTGCTGGCAGAGATGGGGCATGGAGATGAAATTA
TTTTTTCCGATGCTCACTTT

Product: L-fuculokinase

Products: NA

Alternate protein names: L-fuculose kinase [H]

Number of amino acids: Translated: 482; Mature: 482

Protein sequence:

>482_residues
MLSGYIAGAIMKQEVILVLDCGATNVRAIAVNRQGKIVARASTPNASDIAMENNTWHQWSLDAILQRFADCCRQINSELT
DCHIRGIAVTTFGVDGALVDKQGNLLYPIISWKCPRTAAVMDNIERLISEQQLQAISGVGAFSFNTLYKLVWLKENHPQL
LERAHAWLFISSLINHRLTGEFTTDITMAGTSQMLDIQQRDFSPQILQATGIPRRLFPRLVEAGEQIGTLQNSAAAMLGL
PVGIPVISAGHDTQFALFGAGAEQNEPVLSSGTWEILMVRSAQVDTSLLSQYAGSTCELDSQAGLYNPGMQWLASGVLEW
VRKLFWTAETPWQMLIEEARLIAPGADGVKMQCDLLSCQNAGWQGVTLNTTRGHFYRAALEGLTAQLQRNLQMLEKIGHF
KASELLLVGGGSRNTLWNQIKANMLDIPVKVLDDAETTVAGAALFGWYGVGEFNSPEEARAQIHYQYRYFYPQTEPEFIE
EV

Sequences:

>Translated_482_residues
MLSGYIAGAIMKQEVILVLDCGATNVRAIAVNRQGKIVARASTPNASDIAMENNTWHQWSLDAILQRFADCCRQINSELT
DCHIRGIAVTTFGVDGALVDKQGNLLYPIISWKCPRTAAVMDNIERLISEQQLQAISGVGAFSFNTLYKLVWLKENHPQL
LERAHAWLFISSLINHRLTGEFTTDITMAGTSQMLDIQQRDFSPQILQATGIPRRLFPRLVEAGEQIGTLQNSAAAMLGL
PVGIPVISAGHDTQFALFGAGAEQNEPVLSSGTWEILMVRSAQVDTSLLSQYAGSTCELDSQAGLYNPGMQWLASGVLEW
VRKLFWTAETPWQMLIEEARLIAPGADGVKMQCDLLSCQNAGWQGVTLNTTRGHFYRAALEGLTAQLQRNLQMLEKIGHF
KASELLLVGGGSRNTLWNQIKANMLDIPVKVLDDAETTVAGAALFGWYGVGEFNSPEEARAQIHYQYRYFYPQTEPEFIE
EV
>Mature_482_residues
MLSGYIAGAIMKQEVILVLDCGATNVRAIAVNRQGKIVARASTPNASDIAMENNTWHQWSLDAILQRFADCCRQINSELT
DCHIRGIAVTTFGVDGALVDKQGNLLYPIISWKCPRTAAVMDNIERLISEQQLQAISGVGAFSFNTLYKLVWLKENHPQL
LERAHAWLFISSLINHRLTGEFTTDITMAGTSQMLDIQQRDFSPQILQATGIPRRLFPRLVEAGEQIGTLQNSAAAMLGL
PVGIPVISAGHDTQFALFGAGAEQNEPVLSSGTWEILMVRSAQVDTSLLSQYAGSTCELDSQAGLYNPGMQWLASGVLEW
VRKLFWTAETPWQMLIEEARLIAPGADGVKMQCDLLSCQNAGWQGVTLNTTRGHFYRAALEGLTAQLQRNLQMLEKIGHF
KASELLLVGGGSRNTLWNQIKANMLDIPVKVLDDAETTVAGAALFGWYGVGEFNSPEEARAQIHYQYRYFYPQTEPEFIE
EV

Specific function: Fucose metabolism; second step. [C]

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Escherichia coli, GI1789168, Length=482, Percent_Identity=99.3775933609959, Blast_Score=991, Evalue=0.0,
Organism=Escherichia coli, GI1787789, Length=506, Percent_Identity=23.1225296442688, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1789987, Length=421, Percent_Identity=26.1282660332542, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1790338, Length=417, Percent_Identity=25.1798561151079, Blast_Score=90, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR013450 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.51 [H]

Molecular weight: Translated: 53252; Mature: 53252

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS00933 FGGY_KINASES_1 ; PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSGYIAGAIMKQEVILVLDCGATNVRAIAVNRQGKIVARASTPNASDIAMENNTWHQWS
CCCCHHHHHHCCCCEEEEEECCCCCEEEEEEECCCCEEEEECCCCCCCEEECCCCCCEEC
LDAILQRFADCCRQINSELTDCHIRGIAVTTFGVDGALVDKQGNLLYPIISWKCPRTAAV
HHHHHHHHHHHHHHHCCHHCCEEEEEEEEEEECCCCEEEECCCCEEEEEECCCCCCHHHH
MDNIERLISEQQLQAISGVGAFSFNTLYKLVWLKENHPQLLERAHAWLFISSLINHRLTG
HHHHHHHHHHHHHHHHHCCCCHHHHCEEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCC
EFTTDITMAGTSQMLDIQQRDFSPQILQATGIPRRLFPRLVEAGEQIGTLQNSAAAMLGL
CEEEEEEECCCHHHHHHHHCCCCCHHHHHCCCCHHHHHHHHHHHHHHCCHHCCCHHHEEC
PVGIPVISAGHDTQFALFGAGAEQNEPVLSSGTWEILMVRSAQVDTSLLSQYAGSTCELD
CCCCCEEECCCCCEEEEEECCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHCCCCCCCC
SQAGLYNPGMQWLASGVLEWVRKLFWTAETPWQMLIEEARLIAPGADGVKMQCDLLSCQN
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHEECCCCCCCEEEEEEECCCC
AGWQGVTLNTTRGHFYRAALEGLTAQLQRNLQMLEKIGHFKASELLLVGGGSRNTLWNQI
CCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHH
KANMLDIPVKVLDDAETTVAGAALFGWYGVGEFNSPEEARAQIHYQYRYFYPQTEPEFIE
HCCHHHCCHHEECCCHHHHHHHHHHHHCCCCCCCCCHHHHHEEEEEEEEECCCCCHHHHH
EV
CC
>Mature Secondary Structure
MLSGYIAGAIMKQEVILVLDCGATNVRAIAVNRQGKIVARASTPNASDIAMENNTWHQWS
CCCCHHHHHHCCCCEEEEEECCCCCEEEEEEECCCCEEEEECCCCCCCEEECCCCCCEEC
LDAILQRFADCCRQINSELTDCHIRGIAVTTFGVDGALVDKQGNLLYPIISWKCPRTAAV
HHHHHHHHHHHHHHHCCHHCCEEEEEEEEEEECCCCEEEECCCCEEEEEECCCCCCHHHH
MDNIERLISEQQLQAISGVGAFSFNTLYKLVWLKENHPQLLERAHAWLFISSLINHRLTG
HHHHHHHHHHHHHHHHHCCCCHHHHCEEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCC
EFTTDITMAGTSQMLDIQQRDFSPQILQATGIPRRLFPRLVEAGEQIGTLQNSAAAMLGL
CEEEEEEECCCHHHHHHHHCCCCCHHHHHCCCCHHHHHHHHHHHHHHCCHHCCCHHHEEC
PVGIPVISAGHDTQFALFGAGAEQNEPVLSSGTWEILMVRSAQVDTSLLSQYAGSTCELD
CCCCCEEECCCCCEEEEEECCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHCCCCCCCC
SQAGLYNPGMQWLASGVLEWVRKLFWTAETPWQMLIEEARLIAPGADGVKMQCDLLSCQN
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHEECCCCCCCEEEEEEECCCC
AGWQGVTLNTTRGHFYRAALEGLTAQLQRNLQMLEKIGHFKASELLLVGGGSRNTLWNQI
CCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHH
KANMLDIPVKVLDDAETTVAGAALFGWYGVGEFNSPEEARAQIHYQYRYFYPQTEPEFIE
HCCHHHCCHHEECCCHHHHHHHHHHHHCCCCCCCCCHHHHHEEEEEEEEECCCCCHHHHH
EV
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]