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The map label for this gene is hypA [H]

Identifier: 218690850

GI number: 218690850

Start: 3113359

End: 3113709

Strand: Direct

Name: hypA [H]

Synonym: ECED1_3178

Alternate gene names: 218690850

Gene position: 3113359-3113709 (Clockwise)

Preceding gene: 218690837

Following gene: 218690851

Centisome position: 59.76

GC content: 52.71

Gene sequence:

>351_bases
ATGCACGAAATAACCCTCTGCCAACGGGCACTGGAATTGATCGAACAGCAGGCCGCAAAACACGGCGCAAAACGCGTAAC
TGGGGTCTGGCTCAAAATTGGCGCATTTTCTTGTGTCGAAACCAGCTCTCTTGCCTTTTGTTTTGATCTGGTTTGCCGCG
GCAGCGTGGCGGAAGGTTGTAAACTGCACCTCGAAGAACAAGAGGCCGAATGCTGGTGTGAAACATGCCAACAGTATGTG
ACGCTACTGACCCAGCGCGTCCGCCGCTGTCCACTGTGTCATGGTGACATGCTACAGATTGTGGCAGACGACGGTTTACA
GATTCGGCGGATAGAAATAGACCAGGAGTGA

Upstream 100 bases:

>100_bases
TCGACGTGTCATTTCGACATCATCGACATTATTCACCGCAGGGATAATCAACACTGGCACAATTATTGCTTGTAACTGGC
AATAGTTAATGGGAGGCGAT

Downstream 100 bases:

>100_bases
GCGATGTGTACAACATGCGGTTGCGGTGAAGGCAACCTCTATATTGAGGGTGATGAACATAACCCTCATTCCGCGTTTCG
TAGCGCGCCATTTGCCCCGG

Product: hydrogenase nickel incorporation protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 116; Mature: 116

Protein sequence:

>116_residues
MHEITLCQRALELIEQQAAKHGAKRVTGVWLKIGAFSCVETSSLAFCFDLVCRGSVAEGCKLHLEEQEAECWCETCQQYV
TLLTQRVRRCPLCHGDMLQIVADDGLQIRRIEIDQE

Sequences:

>Translated_116_residues
MHEITLCQRALELIEQQAAKHGAKRVTGVWLKIGAFSCVETSSLAFCFDLVCRGSVAEGCKLHLEEQEAECWCETCQQYV
TLLTQRVRRCPLCHGDMLQIVADDGLQIRRIEIDQE
>Mature_116_residues
MHEITLCQRALELIEQQAAKHGAKRVTGVWLKIGAFSCVETSSLAFCFDLVCRGSVAEGCKLHLEEQEAECWCETCQQYV
TLLTQRVRRCPLCHGDMLQIVADDGLQIRRIEIDQE

Specific function: Not required for the formation of hydrogenases 1 and 2. Plays probably a regulatory role [H]

COG id: COG0375

COG function: function code R; Zn finger protein HypA/HybF (possibly regulating hydrogenase expression)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypA/hybF family [H]

Homologues:

Organism=Escherichia coli, GI1789081, Length=116, Percent_Identity=99.1379310344828, Blast_Score=232, Evalue=5e-63,
Organism=Escherichia coli, GI1789365, Length=114, Percent_Identity=49.1228070175439, Blast_Score=120, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000688
- InterPro:   IPR020538 [H]

Pfam domain/function: PF01155 HypA [H]

EC number: NA

Molecular weight: Translated: 13153; Mature: 13153

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS01249 HYPA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

8.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
10.3 %Cys+Met (Translated Protein)
8.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
10.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHEITLCQRALELIEQQAAKHGAKRVTGVWLKIGAFSCVETSSLAFCFDLVCRGSVAEGC
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCHH
KLHLEEQEAECWCETCQQYVTLLTQRVRRCPLCHGDMLQIVADDGLQIRRIEIDQE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHEEECCCCEEEEEECCCC
>Mature Secondary Structure
MHEITLCQRALELIEQQAAKHGAKRVTGVWLKIGAFSCVETSSLAFCFDLVCRGSVAEGC
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCHH
KLHLEEQEAECWCETCQQYVTLLTQRVRRCPLCHGDMLQIVADDGLQIRRIEIDQE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHEEECCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]