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The map label for this gene is pssA [H]

Identifier: 218690702

GI number: 218690702

Start: 2979577

End: 2980932

Strand: Direct

Name: pssA [H]

Synonym: ECED1_3017

Alternate gene names: 218690702

Gene position: 2979577-2980932 (Clockwise)

Preceding gene: 218690701

Following gene: 218690703

Centisome position: 57.19

GC content: 48.75

Gene sequence:

>1356_bases
ATGTTGTCAAAATTTAAGCGTAATAAACATCAACAACACCTTGCCCAACTACCCAAGATTTCTCAATCAGTTGATGATGT
CGATTTCTTTTACGCTCCCGCCGACTTCCGGGAGACGTTGCTGGAAAAAATAGCCAGCGCGAAGCAGCGCATTTGCATTG
TTGCCCTGTATCTCGAACAGGATGACGGTGGCAAAGGCATTCTGAACGCGTTGTATGAGGCTAAAAGGCAGCATCCGGAA
CTGGATGTGCGGGTGCTGGTCGACTGGCATCGTGCACAACGTGGACGCATTGGCGCTGCGGCATCTAACACTAACGCTGA
CTGGTACTGCCGCATGGCGCAGGAAAATCCTGGCGTAGATGTTCCGGTTTATGGCGTTCCAATCAATACCCGTGAAGCCC
TTGGTGTTCTGCACTTTAAAGGCTTTATCATCGACGATAGCGTACTTTATAGCGGTGCCAGCCTGAACGATGTTTACCTG
CATCAGCACGATAAATATCGCTACGACCGTTATCATCTGATCCGTAACCGTAAGATGTCAGACATTATGTTTGAATGGGT
TACACAGAATATTATGAATGGCCGCGGCGTTAATCGTCTGGATGATGTTAATCGGCCAAAAAGCCCGGAAATCAAGAACG
ACATTCGCCTGTTCCGCCAGGAGCTGCGTGATGCCGCTTATCATTTCCAGGGCGATGCCGACAACGATCAGCTTTCCGTA
ACGCCGCTAGTGGGGCTGGGGAAATCGAGTCTGTTGAACAAGACCATTTTCCATCTTATGCCTTGTGCCGAGCAGAAACT
AACCATCTGTACGCCATACTTCAACCTGCCAGCAATCCTTGTGCGCAATATTATCCAGTTGCTGCGCGAAGGGAAAAAGG
TCGAAATTATTGTTGGTGATAAAACCGCGAACGACTTCTACATTCCGGAAGATGAACCTTTCAAGATAATTGGCGCATTG
CCTTATCTCTATGAGATCAATCTGCGTCGTTTCCTGAGTCGTTTACAGTATTACGTCAACACTGACCAGTTAGTAGTTCG
GTTATGGAAAGATGACGACAACACCTATCACCTGAAAGGGATGTGGGTTGATGATAAGTGGATGTTGATCACCGGTAATA
ACCTGAACCCGCGCGCCTGGCGTCTGGATCTGGAAAACGCCATTTTGATCCACGATCCGCAACTGGAGCTTGCGCCACAG
CGAGAGAAAGAACTGGATCTGATCCGCGAGCATACCACCATCGTTAAGCACTACCGCGATCTGCAAAGTATTGCCGATTA
TCCGGTGAAGGTTCGTAAACTCATCCGCCGTTTGCGCCGTATCCGCATCGACCGATTAATTAGCCGCATCCTGTAA

Upstream 100 bases:

>100_bases
AATGTTGACCACTTAATCGGGACTGGTGTTATTATTGCCCGCTTATGTCGTCTGCATTGCACAGAGGACCCTTCAATGAA
CAGAGAAGAAATGCACTGTG

Downstream 100 bases:

>100_bases
TCACAACCCCGTCCTGTACGGGGTTTGTTTTTTGGAGGCCACGTTTTGCGTATTCTTTTTGTCTGTTCGCTATTGTTACT
TTCTGGATGCAGCCATATGG

Product: phosphatidylserine synthase

Products: NA

Alternate protein names: Phosphatidylserine synthase [H]

Number of amino acids: Translated: 451; Mature: 451

Protein sequence:

>451_residues
MLSKFKRNKHQQHLAQLPKISQSVDDVDFFYAPADFRETLLEKIASAKQRICIVALYLEQDDGGKGILNALYEAKRQHPE
LDVRVLVDWHRAQRGRIGAAASNTNADWYCRMAQENPGVDVPVYGVPINTREALGVLHFKGFIIDDSVLYSGASLNDVYL
HQHDKYRYDRYHLIRNRKMSDIMFEWVTQNIMNGRGVNRLDDVNRPKSPEIKNDIRLFRQELRDAAYHFQGDADNDQLSV
TPLVGLGKSSLLNKTIFHLMPCAEQKLTICTPYFNLPAILVRNIIQLLREGKKVEIIVGDKTANDFYIPEDEPFKIIGAL
PYLYEINLRRFLSRLQYYVNTDQLVVRLWKDDDNTYHLKGMWVDDKWMLITGNNLNPRAWRLDLENAILIHDPQLELAPQ
REKELDLIREHTTIVKHYRDLQSIADYPVKVRKLIRRLRRIRIDRLISRIL

Sequences:

>Translated_451_residues
MLSKFKRNKHQQHLAQLPKISQSVDDVDFFYAPADFRETLLEKIASAKQRICIVALYLEQDDGGKGILNALYEAKRQHPE
LDVRVLVDWHRAQRGRIGAAASNTNADWYCRMAQENPGVDVPVYGVPINTREALGVLHFKGFIIDDSVLYSGASLNDVYL
HQHDKYRYDRYHLIRNRKMSDIMFEWVTQNIMNGRGVNRLDDVNRPKSPEIKNDIRLFRQELRDAAYHFQGDADNDQLSV
TPLVGLGKSSLLNKTIFHLMPCAEQKLTICTPYFNLPAILVRNIIQLLREGKKVEIIVGDKTANDFYIPEDEPFKIIGAL
PYLYEINLRRFLSRLQYYVNTDQLVVRLWKDDDNTYHLKGMWVDDKWMLITGNNLNPRAWRLDLENAILIHDPQLELAPQ
REKELDLIREHTTIVKHYRDLQSIADYPVKVRKLIRRLRRIRIDRLISRIL
>Mature_451_residues
MLSKFKRNKHQQHLAQLPKISQSVDDVDFFYAPADFRETLLEKIASAKQRICIVALYLEQDDGGKGILNALYEAKRQHPE
LDVRVLVDWHRAQRGRIGAAASNTNADWYCRMAQENPGVDVPVYGVPINTREALGVLHFKGFIIDDSVLYSGASLNDVYL
HQHDKYRYDRYHLIRNRKMSDIMFEWVTQNIMNGRGVNRLDDVNRPKSPEIKNDIRLFRQELRDAAYHFQGDADNDQLSV
TPLVGLGKSSLLNKTIFHLMPCAEQKLTICTPYFNLPAILVRNIIQLLREGKKVEIIVGDKTANDFYIPEDEPFKIIGAL
PYLYEINLRRFLSRLQYYVNTDQLVVRLWKDDDNTYHLKGMWVDDKWMLITGNNLNPRAWRLDLENAILIHDPQLELAPQ
REKELDLIREHTTIVKHYRDLQSIADYPVKVRKLIRRLRRIRIDRLISRIL

Specific function: Unknown

COG id: COG1502

COG function: function code I; Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PLD phosphodiesterase domains [H]

Homologues:

Organism=Escherichia coli, GI87082134, Length=451, Percent_Identity=99.5565410199557, Blast_Score=922, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25143331, Length=461, Percent_Identity=26.0303687635575, Blast_Score=96, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6319842, Length=343, Percent_Identity=24.7813411078717, Blast_Score=73, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016270
- InterPro:   IPR001736 [H]

Pfam domain/function: PF00614 PLDc [H]

EC number: =2.7.8.8 [H]

Molecular weight: Translated: 52769; Mature: 52769

Theoretical pI: Translated: 9.20; Mature: 9.20

Prosite motif: PS50035 PLD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSKFKRNKHQQHLAQLPKISQSVDDVDFFYAPADFRETLLEKIASAKQRICIVALYLEQ
CCCHHHHHHHHHHHHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHCCCEEEEEEEEEC
DDGGKGILNALYEAKRQHPELDVRVLVDWHRAQRGRIGAAASNTNADWYCRMAQENPGVD
CCCCHHHHHHHHHHHHCCCCCEEEEEEEEHHHCCCCCCCCCCCCCCCEEEEECCCCCCCC
VPVYGVPINTREALGVLHFKGFIIDDSVLYSGASLNDVYLHQHDKYRYDRYHLIRNRKMS
CEEEECCCCCHHHHEEEEEEEEEEECHHHCCCCCCCEEEEECCCCCCHHHHHHHHCCCHH
DIMFEWVTQNIMNGRGVNRLDDVNRPKSPEIKNDIRLFRQELRDAAYHFQGDADNDQLSV
HHHHHHHHHHHHCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEE
TPLVGLGKSSLLNKTIFHLMPCAEQKLTICTPYFNLPAILVRNIIQLLREGKKVEIIVGD
EEEECCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCEEEEEECC
KTANDFYIPEDEPFKIIGALPYLYEINLRRFLSRLQYYVNTDQLVVRLWKDDDNTYHLKG
CCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEEE
MWVDDKWMLITGNNLNPRAWRLDLENAILIHDPQLELAPQREKELDLIREHTTIVKHYRD
EEECCEEEEEECCCCCCCEEEEECCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LQSIADYPVKVRKLIRRLRRIRIDRLISRIL
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MLSKFKRNKHQQHLAQLPKISQSVDDVDFFYAPADFRETLLEKIASAKQRICIVALYLEQ
CCCHHHHHHHHHHHHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHCCCEEEEEEEEEC
DDGGKGILNALYEAKRQHPELDVRVLVDWHRAQRGRIGAAASNTNADWYCRMAQENPGVD
CCCCHHHHHHHHHHHHCCCCCEEEEEEEEHHHCCCCCCCCCCCCCCCEEEEECCCCCCCC
VPVYGVPINTREALGVLHFKGFIIDDSVLYSGASLNDVYLHQHDKYRYDRYHLIRNRKMS
CEEEECCCCCHHHHEEEEEEEEEEECHHHCCCCCCCEEEEECCCCCCHHHHHHHHCCCHH
DIMFEWVTQNIMNGRGVNRLDDVNRPKSPEIKNDIRLFRQELRDAAYHFQGDADNDQLSV
HHHHHHHHHHHHCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEE
TPLVGLGKSSLLNKTIFHLMPCAEQKLTICTPYFNLPAILVRNIIQLLREGKKVEIIVGD
EEEECCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCEEEEEECC
KTANDFYIPEDEPFKIIGALPYLYEINLRRFLSRLQYYVNTDQLVVRLWKDDDNTYHLKG
CCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEEE
MWVDDKWMLITGNNLNPRAWRLDLENAILIHDPQLELAPQREKELDLIREHTTIVKHYRD
EEECCEEEEEECCCCCCCEEEEECCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LQSIADYPVKVRKLIRRLRRIRIDRLISRIL
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2002065; 9205837; 9278503; 1323044 [H]