Click here to switch to the map view.

The map label for this gene is xseA [H]

Identifier: 218690624

GI number: 218690624

Start: 2884682

End: 2886058

Strand: Direct

Name: xseA [H]

Synonym: ECED1_2933

Alternate gene names: 218690624

Gene position: 2884682-2886058 (Clockwise)

Preceding gene: 218690621

Following gene: 218690641

Centisome position: 55.37

GC content: 53.45

Gene sequence:

>1377_bases
ATGTTACCTTCTCAATCCCCTGCAATTTTTACCGTTAGCCGCCTGAATCAAACGGTTCGTCTGCTGCTTGAGCATGAGAT
GGGGCAGGTGTGGATCAGCGGCGAAATCTCTAATTTTACACAACCAGCCTCCGGTCACTGGTACTTTACGCTTAAAGACG
ATACCGCGCAGGTGCGCTGTGCGATGTTCCGAAACAGCAACCGCCGGGTCACCTTCCGCCCACAGCACGGGCAACAGGTT
TTAGTTCGCGCCAATATTACGCTCTACGAGCCGCGCGGTGACTACCAGATTATCGTCGAAAGTATGCAGCCTGCCGGTGA
AGGGTTGCTGCAACAGAAGTACGAACAGCTTAAAGCGAAGTTGCAGACTGAAGGTTTGTTCGATCTGCAATACAAAAAAT
CACTCCCCTCCCCTGCGCATTGCGTTGGTGTGATCACCTCAAAAACCGGTGCTGCGCTACATGATATTTTGCATGTGTTA
AAACGTCGCGATCCTTCTCTGCCGGTGATCATCTACTCCACCGCCGTACAGGGGGATGATGCGCCGGGGCAAATCGTTCG
TGCCATTGAACTGGCGAATAAGCGCAACGAGTGTGACGTGTTGATCGTTGGCCGTGGCGGTGGTTCGCTGGAAGATTTAT
GGAGTTTTAATGATGAGCGTGTGGCGCGGGCGATTTTTGCCAGTCGCATTCCGATAGTCAGCGCCGTCGGGCATGAAACC
GATGTGACAATTGCTGACTTTGTTGCTGATCTACGTGCGCCAACGCCGTCAGCCGCCGCTGAAGTGGTGAGCCGTAATCA
GCAAGAATTGCTACGTCAGGTGCAATCGACCCGTCAACGGCTGGAGATGGCGATGGACTATTATCTCGCCAATCGCACGC
GGCGCTTTACGCAGATCCATCACCGATTACAGCAACAGCATCCGCAGCTCCGGCTGGCACGTCAGCAAACTATGCTCGAA
CGTCTGCAAAAGCGGATGAGCTTTGCGCTGGAGAATCAGCTTAAACGCGCGGGTCAGCAACAGCAGCGATTAACACGGCA
ACTCGTCCAGCAAAATCCGCAGTCGCGTATTCATCGCGCGCAAACGCGCATTCAGCAACTGGAATATCGTTTAGCAGAAA
CCCTGCGCGCACAGCTTAGCGCCACGCGTGAACGTTTCGGTAATGCAGTAACACACCTCGAAGCCGTAAGCCCACTGTCA
ACGCTGGCGCGCGGTTATAGCGTCACCAGCGCCGCTGATGGCGCGGTGTTAAAACAGGTTAAGCAAGTGAAAGTGGGTGA
GACACTGATCACACGACTGGGAGATGGTGTGGTGATTAGTGAAGTCAGCGCCGTAACAAAAACCCGCAAATCACGTAAAA
AAACGTCTAATCCGTAG

Upstream 100 bases:

>100_bases
GATTGCATCTACCCCTTTTTGCAAAAAATGCTTGCTATCCCCGGAGGGCGGGTTACTATCGACTGAATAACCTGCTGATT
TAGAATTTGATCTCGCTCAC

Downstream 100 bases:

>100_bases
ACCGGATAAGAGGCGCCAGCATCGCATCCGGCAATAACTCCCAGGCTACTCCAGATCCGCCATGCTGGTTACTGGAAGCA
GGTCACCAGACCCGGTTTAT

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MLPSQSPAIFTVSRLNQTVRLLLEHEMGQVWISGEISNFTQPASGHWYFTLKDDTAQVRCAMFRNSNRRVTFRPQHGQQV
LVRANITLYEPRGDYQIIVESMQPAGEGLLQQKYEQLKAKLQTEGLFDLQYKKSLPSPAHCVGVITSKTGAALHDILHVL
KRRDPSLPVIIYSTAVQGDDAPGQIVRAIELANKRNECDVLIVGRGGGSLEDLWSFNDERVARAIFASRIPIVSAVGHET
DVTIADFVADLRAPTPSAAAEVVSRNQQELLRQVQSTRQRLEMAMDYYLANRTRRFTQIHHRLQQQHPQLRLARQQTMLE
RLQKRMSFALENQLKRAGQQQQRLTRQLVQQNPQSRIHRAQTRIQQLEYRLAETLRAQLSATRERFGNAVTHLEAVSPLS
TLARGYSVTSAADGAVLKQVKQVKVGETLITRLGDGVVISEVSAVTKTRKSRKKTSNP

Sequences:

>Translated_458_residues
MLPSQSPAIFTVSRLNQTVRLLLEHEMGQVWISGEISNFTQPASGHWYFTLKDDTAQVRCAMFRNSNRRVTFRPQHGQQV
LVRANITLYEPRGDYQIIVESMQPAGEGLLQQKYEQLKAKLQTEGLFDLQYKKSLPSPAHCVGVITSKTGAALHDILHVL
KRRDPSLPVIIYSTAVQGDDAPGQIVRAIELANKRNECDVLIVGRGGGSLEDLWSFNDERVARAIFASRIPIVSAVGHET
DVTIADFVADLRAPTPSAAAEVVSRNQQELLRQVQSTRQRLEMAMDYYLANRTRRFTQIHHRLQQQHPQLRLARQQTMLE
RLQKRMSFALENQLKRAGQQQQRLTRQLVQQNPQSRIHRAQTRIQQLEYRLAETLRAQLSATRERFGNAVTHLEAVSPLS
TLARGYSVTSAADGAVLKQVKQVKVGETLITRLGDGVVISEVSAVTKTRKSRKKTSNP
>Mature_458_residues
MLPSQSPAIFTVSRLNQTVRLLLEHEMGQVWISGEISNFTQPASGHWYFTLKDDTAQVRCAMFRNSNRRVTFRPQHGQQV
LVRANITLYEPRGDYQIIVESMQPAGEGLLQQKYEQLKAKLQTEGLFDLQYKKSLPSPAHCVGVITSKTGAALHDILHVL
KRRDPSLPVIIYSTAVQGDDAPGQIVRAIELANKRNECDVLIVGRGGGSLEDLWSFNDERVARAIFASRIPIVSAVGHET
DVTIADFVADLRAPTPSAAAEVVSRNQQELLRQVQSTRQRLEMAMDYYLANRTRRFTQIHHRLQQQHPQLRLARQQTMLE
RLQKRMSFALENQLKRAGQQQQRLTRQLVQQNPQSRIHRAQTRIQQLEYRLAETLRAQLSATRERFGNAVTHLEAVSPLS
TLARGYSVTSAADGAVLKQVKQVKVGETLITRLGDGVVISEVSAVTKTRKSRKKTSNP

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family [H]

Homologues:

Organism=Escherichia coli, GI1788856, Length=454, Percent_Identity=92.9515418502203, Blast_Score=847, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti [H]

EC number: =3.1.11.6 [H]

Molecular weight: Translated: 51648; Mature: 51648

Theoretical pI: Translated: 10.72; Mature: 10.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPSQSPAIFTVSRLNQTVRLLLEHEMGQVWISGEISNFTQPASGHWYFTLKDDTAQVRC
CCCCCCCCEEEHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCEEEEEECCCHHHHH
AMFRNSNRRVTFRPQHGQQVLVRANITLYEPRGDYQIIVESMQPAGEGLLQQKYEQLKAK
HHHCCCCCEEEECCCCCCEEEEEEEEEEECCCCCHHHHEEHHCCCCCHHHHHHHHHHHHH
LQTEGLFDLQYKKSLPSPAHCVGVITSKTGAALHDILHVLKRRDPSLPVIIYSTAVQGDD
HHHCCCEEEHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCEEEEEEEECCCC
APGQIVRAIELANKRNECDVLIVGRGGGSLEDLWSFNDERVARAIFASRIPIVSAVGHET
CHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHCCCHHHHHHHHHHHCCCHHHHCCCCC
DVTIADFVADLRAPTPSAAAEVVSRNQQELLRQVQSTRQRLEMAMDYYLANRTRRFTQIH
CCHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HRLQQQHPQLRLARQQTMLERLQKRMSFALENQLKRAGQQQQRLTRQLVQQNPQSRIHRA
HHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
QTRIQQLEYRLAETLRAQLSATRERFGNAVTHLEAVSPLSTLARGYSVTSAADGAVLKQV
HHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
KQVKVGETLITRLGDGVVISEVSAVTKTRKSRKKTSNP
HHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLPSQSPAIFTVSRLNQTVRLLLEHEMGQVWISGEISNFTQPASGHWYFTLKDDTAQVRC
CCCCCCCCEEEHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCEEEEEECCCHHHHH
AMFRNSNRRVTFRPQHGQQVLVRANITLYEPRGDYQIIVESMQPAGEGLLQQKYEQLKAK
HHHCCCCCEEEECCCCCCEEEEEEEEEEECCCCCHHHHEEHHCCCCCHHHHHHHHHHHHH
LQTEGLFDLQYKKSLPSPAHCVGVITSKTGAALHDILHVLKRRDPSLPVIIYSTAVQGDD
HHHCCCEEEHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCEEEEEEEECCCC
APGQIVRAIELANKRNECDVLIVGRGGGSLEDLWSFNDERVARAIFASRIPIVSAVGHET
CHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHCCCHHHHHHHHHHHCCCHHHHCCCCC
DVTIADFVADLRAPTPSAAAEVVSRNQQELLRQVQSTRQRLEMAMDYYLANRTRRFTQIH
CCHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HRLQQQHPQLRLARQQTMLERLQKRMSFALENQLKRAGQQQQRLTRQLVQQNPQSRIHRA
HHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
QTRIQQLEYRLAETLRAQLSATRERFGNAVTHLEAVSPLSTLARGYSVTSAADGAVLKQV
HHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
KQVKVGETLITRLGDGVVISEVSAVTKTRKSRKKTSNP
HHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA