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The map label for this gene is ccmF [H]

Identifier: 218690358

GI number: 218690358

Start: 2584001

End: 2585944

Strand: Reverse

Name: ccmF [H]

Synonym: ECED1_2661

Alternate gene names: 218690358

Gene position: 2585944-2584001 (Counterclockwise)

Preceding gene: 218690359

Following gene: 218690357

Centisome position: 49.64

GC content: 56.94

Gene sequence:

>1944_bases
ATGATGCCAGAAATTGGTAACGGGCTGCTGTGTCTGGCGCTAGGAATTGCGCTGCTGCTGTCCGTGTATCCGCTATGGGG
CGTGGCGCGCGGGGACGCGCGCATGATGGCGTCTTCCCGCTTGTTTGCCTGGCTGCTGTTTATGTCTGTGGCTGGCGCAT
TTCTGGTGCTGGTCAATGCTTTCGTGGTCAACGACTTTACCGTCACCTATGTTGCCAGCAACTCCAATACCCAGCTTCCG
GTGTGGTATCGCGTGGCGGCTACCTGGGGTGCGCATGAAGGCTCGCTCCTGCTGTGGGTGCTGCTGATGAGCGGCTGGAC
CTTTGCGGTAGCGATTTTTAGTCAGCGTATTCCGCTGGATATTGTGGCCCGCGTACTGGCGATAATGGGGATGGTCAGCG
TCGGCTTTTTGCTGTTCATTCTCTTTACCTCTAACCCGTTCTCACGCACGTTGCCGAACTTCCCGATTGAAGGTCGCGAT
CTTAACCCGCTGTTACAGGATCCGGGGCTGATCTTCCATCCGCCTCTGCTTTATATGGGGTACGTCGGCTTCTCGGTGGC
GTTTGCTTTTGCCATTGCATCTTTGTTGAGTGGGCGTCTGGACAGCACTTATGCGCGTTTTACTCGTCCGTGGACGCTGG
CTGCGTGGATCTTCCTGACGCTCGGCATTGTGCTCGGTTCCGCATGGGCCTATTACGAACTCGGCTGGGGCGGCTGGTGG
TTCTGGGATCCGGTAGAAAACGCCTCGTTTATGCCGTGGCTGGTGGGGACTGCGCTGATGCACTCACTGGCGGTCACTGA
ACAACGCGCCAGCTTCAAAGCGTGGACATTACTGCTGGCAATCAGTGCCTTCTCGTTGTGTCTGCTGGGGACTTTCCTGG
TGCGTTCCGGCGTGCTGGTATCGGTACACGCGTTTGCGTCTGATCCGGCGCGCGGTATGTTTATCCTCGCCTTTATGGTG
CTGGTGATTGGCGGTTCGCTGCTGCTGTTTGCCGCGCGTGGACACAAAGTTCGCTCACGCGTAAACAATGCGCTGTGGTC
GCGGGAATCTTTGCTGTTAGCGAACAACGTTTTGCTGGTCGCCGCGATGCTGGTGGTGTTGCTGGGGACGTTGCTGCCGC
TGGTGCACAAGCAACTGGGACTGGGCAGTATTTCGATTGGCGAACCGTTCTTCAACACCATGTTTACCTGGCTGATGGTG
CCGTTTGCGCTACTGCTTGGTGTCGGCCCTCTGGTGCGCTGGGGACGCGATCGCCCACGTAAAATCCGCAATTTGTTGAT
TATCGCCTTCATCTCTACGCTGGTGCTGTCGCTGCTGTTGCCGTGGCTGTTCGAAAGCAAAGTTGTGGCGATGACGGTGC
TCGGCCTGGCAATGGCCTGCTGGATTGCGGTGCTGGCAATTGCGGAAGCTGCGCTGCGTATTTCACGCGGCACGAAAACC
ACCTTCAGTTATTGGGGGATGGTGGCAGCTCACCTGGGGCTGGCAGTGACAATTGTTGGCATTGCTTTTAGTCAGAACTA
TAGCGTTGAGCGTGATGTGCGCATGAAGTCCGGCGATAGCGTCGATATTCATGAATATCGCTTCACCTTCCGTGATGTCA
AAGAAGTGACTGGTCCAAACTGGCGTGGCGGTGTGGCGACCATCGGCGTAACGCGAGATGGAAAGCCGGAAACAGTGCTG
TATGCAGAAAAACGTTATTACAACACTGCCGGGTCGATGATGACCGAAGCGGCGATTGACGGTGGCATCACGCGTGACCT
GTACGCGGCGCTCGGTGAAGAGCTGGAAAACGGCGCGTGGGCCGTGCGTCTTTACTACAAACCATTTGTTCGCTGGATTT
GGGCGGGCGGGCTGATGATGGCGTTGGGCGGACTGCTGTGTCTGTTTGATCCTCGCTATCGTAAGCGCGTGAACCCGCAG
AAAACTGCGCCGGAGGCTGCATGA

Upstream 100 bases:

>100_bases
TGCTGGCGAAACACGATGAAAACTACACGCCGCCAGAAGTTGAGAAAGCGATGGAAGCTAACCACCGTCGCCCGGCGAGT
GTTTATAAGGACCCAGCATC

Downstream 100 bases:

>100_bases
AGCGCAAGGTATTGTTAATTCCGTTGATTATCTTCCTGGCGATTACCGCGGCGCTGCTGTGGCAGCTGGCGCGTAATGCC
GAAGGGGATGATCCGACCAA

Product: heme lyase CcmF

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 647; Mature: 647

Protein sequence:

>647_residues
MMPEIGNGLLCLALGIALLLSVYPLWGVARGDARMMASSRLFAWLLFMSVAGAFLVLVNAFVVNDFTVTYVASNSNTQLP
VWYRVAATWGAHEGSLLLWVLLMSGWTFAVAIFSQRIPLDIVARVLAIMGMVSVGFLLFILFTSNPFSRTLPNFPIEGRD
LNPLLQDPGLIFHPPLLYMGYVGFSVAFAFAIASLLSGRLDSTYARFTRPWTLAAWIFLTLGIVLGSAWAYYELGWGGWW
FWDPVENASFMPWLVGTALMHSLAVTEQRASFKAWTLLLAISAFSLCLLGTFLVRSGVLVSVHAFASDPARGMFILAFMV
LVIGGSLLLFAARGHKVRSRVNNALWSRESLLLANNVLLVAAMLVVLLGTLLPLVHKQLGLGSISIGEPFFNTMFTWLMV
PFALLLGVGPLVRWGRDRPRKIRNLLIIAFISTLVLSLLLPWLFESKVVAMTVLGLAMACWIAVLAIAEAALRISRGTKT
TFSYWGMVAAHLGLAVTIVGIAFSQNYSVERDVRMKSGDSVDIHEYRFTFRDVKEVTGPNWRGGVATIGVTRDGKPETVL
YAEKRYYNTAGSMMTEAAIDGGITRDLYAALGEELENGAWAVRLYYKPFVRWIWAGGLMMALGGLLCLFDPRYRKRVNPQ
KTAPEAA

Sequences:

>Translated_647_residues
MMPEIGNGLLCLALGIALLLSVYPLWGVARGDARMMASSRLFAWLLFMSVAGAFLVLVNAFVVNDFTVTYVASNSNTQLP
VWYRVAATWGAHEGSLLLWVLLMSGWTFAVAIFSQRIPLDIVARVLAIMGMVSVGFLLFILFTSNPFSRTLPNFPIEGRD
LNPLLQDPGLIFHPPLLYMGYVGFSVAFAFAIASLLSGRLDSTYARFTRPWTLAAWIFLTLGIVLGSAWAYYELGWGGWW
FWDPVENASFMPWLVGTALMHSLAVTEQRASFKAWTLLLAISAFSLCLLGTFLVRSGVLVSVHAFASDPARGMFILAFMV
LVIGGSLLLFAARGHKVRSRVNNALWSRESLLLANNVLLVAAMLVVLLGTLLPLVHKQLGLGSISIGEPFFNTMFTWLMV
PFALLLGVGPLVRWGRDRPRKIRNLLIIAFISTLVLSLLLPWLFESKVVAMTVLGLAMACWIAVLAIAEAALRISRGTKT
TFSYWGMVAAHLGLAVTIVGIAFSQNYSVERDVRMKSGDSVDIHEYRFTFRDVKEVTGPNWRGGVATIGVTRDGKPETVL
YAEKRYYNTAGSMMTEAAIDGGITRDLYAALGEELENGAWAVRLYYKPFVRWIWAGGLMMALGGLLCLFDPRYRKRVNPQ
KTAPEAA
>Mature_647_residues
MMPEIGNGLLCLALGIALLLSVYPLWGVARGDARMMASSRLFAWLLFMSVAGAFLVLVNAFVVNDFTVTYVASNSNTQLP
VWYRVAATWGAHEGSLLLWVLLMSGWTFAVAIFSQRIPLDIVARVLAIMGMVSVGFLLFILFTSNPFSRTLPNFPIEGRD
LNPLLQDPGLIFHPPLLYMGYVGFSVAFAFAIASLLSGRLDSTYARFTRPWTLAAWIFLTLGIVLGSAWAYYELGWGGWW
FWDPVENASFMPWLVGTALMHSLAVTEQRASFKAWTLLLAISAFSLCLLGTFLVRSGVLVSVHAFASDPARGMFILAFMV
LVIGGSLLLFAARGHKVRSRVNNALWSRESLLLANNVLLVAAMLVVLLGTLLPLVHKQLGLGSISIGEPFFNTMFTWLMV
PFALLLGVGPLVRWGRDRPRKIRNLLIIAFISTLVLSLLLPWLFESKVVAMTVLGLAMACWIAVLAIAEAALRISRGTKT
TFSYWGMVAAHLGLAVTIVGIAFSQNYSVERDVRMKSGDSVDIHEYRFTFRDVKEVTGPNWRGGVATIGVTRDGKPETVL
YAEKRYYNTAGSMMTEAAIDGGITRDLYAALGEELENGAWAVRLYYKPFVRWIWAGGLMMALGGLLCLFDPRYRKRVNPQ
KTAPEAA

Specific function: Required for the biogenesis of c-type cytochromes. Possible subunit of a heme lyase [H]

COG id: COG1138

COG function: function code O; Cytochrome c biogenesis factor

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ccmF/cycK/ccl1/nrfE/ccsA family [H]

Homologues:

Organism=Escherichia coli, GI1788524, Length=646, Percent_Identity=99.8452012383901, Blast_Score=1281, Evalue=0.0,
Organism=Escherichia coli, GI1790511, Length=581, Percent_Identity=38.5542168674699, Blast_Score=314, Evalue=1e-86,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002541
- InterPro:   IPR003567
- InterPro:   IPR003568 [H]

Pfam domain/function: PF01578 Cytochrom_C_asm [H]

EC number: NA

Molecular weight: Translated: 71389; Mature: 71389

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMPEIGNGLLCLALGIALLLSVYPLWGVARGDARMMASSRLFAWLLFMSVAGAFLVLVNA
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVVNDFTVTYVASNSNTQLPVWYRVAATWGAHEGSLLLWVLLMSGWTFAVAIFSQRIPLD
HHHCCEEEEEEECCCCCCCEEEEEEEECCCCCCCHHHHHHHHHCCHHHHHHHHHCCCCHH
IVARVLAIMGMVSVGFLLFILFTSNPFSRTLPNFPIEGRDLNPLLQDPGLIFHPPLLYMG
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCHHHHCCCCEECCHHHHHH
YVGFSVAFAFAIASLLSGRLDSTYARFTRPWTLAAWIFLTLGIVLGSAWAYYELGWGGWW
HHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHEEEECCCCEE
FWDPVENASFMPWLVGTALMHSLAVTEQRASFKAWTLLLAISAFSLCLLGTFLVRSGVLV
EECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
SVHAFASDPARGMFILAFMVLVIGGSLLLFAARGHKVRSRVNNALWSRESLLLANNVLLV
EEEECCCCCCCHHHHHHHHHHHHCCHHEEEECCCHHHHHHHHHHHHCCCHHHHHHHHHHH
AAMLVVLLGTLLPLVHKQLGLGSISIGEPFFNTMFTWLMVPFALLLGVGPLVRWGRDRPR
HHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCHH
KIRNLLIIAFISTLVLSLLLPWLFESKVVAMTVLGLAMACWIAVLAIAEAALRISRGTKT
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
TFSYWGMVAAHLGLAVTIVGIAFSQNYSVERDVRMKSGDSVDIHEYRFTFRDVKEVTGPN
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHCCCC
WRGGVATIGVTRDGKPETVLYAEKRYYNTAGSMMTEAAIDGGITRDLYAALGEELENGAW
CCCCEEEEEECCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCE
AVRLYYKPFVRWIWAGGLMMALGGLLCLFDPRYRKRVNPQKTAPEAA
EEEEHHHHHHHHHHHCCHHHHHCCHHHHCCCHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MMPEIGNGLLCLALGIALLLSVYPLWGVARGDARMMASSRLFAWLLFMSVAGAFLVLVNA
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVVNDFTVTYVASNSNTQLPVWYRVAATWGAHEGSLLLWVLLMSGWTFAVAIFSQRIPLD
HHHCCEEEEEEECCCCCCCEEEEEEEECCCCCCCHHHHHHHHHCCHHHHHHHHHCCCCHH
IVARVLAIMGMVSVGFLLFILFTSNPFSRTLPNFPIEGRDLNPLLQDPGLIFHPPLLYMG
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCHHHHCCCCEECCHHHHHH
YVGFSVAFAFAIASLLSGRLDSTYARFTRPWTLAAWIFLTLGIVLGSAWAYYELGWGGWW
HHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHEEEECCCCEE
FWDPVENASFMPWLVGTALMHSLAVTEQRASFKAWTLLLAISAFSLCLLGTFLVRSGVLV
EECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
SVHAFASDPARGMFILAFMVLVIGGSLLLFAARGHKVRSRVNNALWSRESLLLANNVLLV
EEEECCCCCCCHHHHHHHHHHHHCCHHEEEECCCHHHHHHHHHHHHCCCHHHHHHHHHHH
AAMLVVLLGTLLPLVHKQLGLGSISIGEPFFNTMFTWLMVPFALLLGVGPLVRWGRDRPR
HHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCHH
KIRNLLIIAFISTLVLSLLLPWLFESKVVAMTVLGLAMACWIAVLAIAEAALRISRGTKT
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
TFSYWGMVAAHLGLAVTIVGIAFSQNYSVERDVRMKSGDSVDIHEYRFTFRDVKEVTGPN
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHCCCC
WRGGVATIGVTRDGKPETVLYAEKRYYNTAGSMMTEAAIDGGITRDLYAALGEELENGAW
CCCCEEEEEECCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCE
AVRLYYKPFVRWIWAGGLMMALGGLLCLFDPRYRKRVNPQKTAPEAA
EEEEHHHHHHHHHHHCCHHHHHCCHHHHCCCHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 7635817 [H]