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The map label for this gene is galE [H]

Identifier: 218690098

GI number: 218690098

Start: 2319224

End: 2320261

Strand: Reverse

Name: galE [H]

Synonym: ECED1_2386

Alternate gene names: 218690098

Gene position: 2320261-2319224 (Counterclockwise)

Preceding gene: 218690099

Following gene: 218690097

Centisome position: 44.54

GC content: 32.85

Gene sequence:

>1038_bases
TTGTTAATGGAGCCATATATGTCAATTTTAGTTACCGGAGGTTGTGGTTATATAGGTGTCCACACAATTTATACGTTAAT
TTCTCAGGGCTACGATGTTATTGTACTGGATAACCTGACTAACTCATCAATAGAGTCATTAGAGAGAGTCAAGTTAATGA
CAAATCATAACATACCCTTTTATAAAGGAGATGTGGGGAATAAAAAAATATTGGTAGACATATTCAATGAGCATCAAATA
AAAGCGGTTATGCATTTTGCAGGCTTGAAATCAGTAAGTGAATCTATAAAAAAACCGATTGAATATTATTCAAGTAACGT
AATGCAAACGTTATCACTAATATCTACAATGATAGAGTATAACGTAAAAAGCTTTATCTTTAGTTCATCTGCTACTGTAT
ATGGTAAACCAAAGTTATGCCCTATAAATGAAACTCATCCTATTGGCAAAACTACAAATCCTTATGGAACATCAAAATTA
ATGATGGAGTTAATGTTGTCTGATTTGTGTAATGCATATGATGATTTTAATGTGACAATTTTACGATATTTTAATCCAAT
TGGTGCTCATGAATCAGGTAATATTGGTGAACATCCAAACGGTATACCAAATAACCTATTTCCTTATCTTACAAAAGTTG
CTATTGGAGAGTATCCTTATTTAAAAGTGTATGGTTGTGATTACCCAACGTCTGATGGTTCTGGTGTTCGAGATTATATT
CATGTAGTTGATCTTGCTGAAGCACATGTAAAAGCTTTATCAAAAAATTCAGAGTCGACTGGGCTAAAAATTTATAATTT
AGGAACCGGAAAAGGATATTCTGTACTCGAAGTTATAGAAGCTTTTGAAAAGATAACTGGAATCAAAATACCATATAAAA
TTATGCCTCGAAGGGATGGTGATGTTGCGGAGTGTTGGTCTGATAGCACGAAGGCAAATGATAAATTAGAATGGAAAGCA
AACAGAGAATTATATGACATGATTAGAGACGCTTGGAATTGGCAATCAAAAAATCCTCATGGTTATGATAATACATGA

Upstream 100 bases:

>100_bases
GATTTTATTCTAAAAAAGAATTGGATGAATTGAAAGTTATTTTGAGCTTAATTTATTAAACTTGAAGTTTTTTTACTGAG
TTTTTCTGAAAAATAATTTA

Downstream 100 bases:

>100_bases
TGTTATAGTATATTCAATGAATATAATTTATGCTTTGGAGTAAAAGTTGTCACAGCGTTTTCTTGCAGAACTAAGATGTT
TTTAGCATAATTAGACACAG

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MLMEPYMSILVTGGCGYIGVHTIYTLISQGYDVIVLDNLTNSSIESLERVKLMTNHNIPFYKGDVGNKKILVDIFNEHQI
KAVMHFAGLKSVSESIKKPIEYYSSNVMQTLSLISTMIEYNVKSFIFSSSATVYGKPKLCPINETHPIGKTTNPYGTSKL
MMELMLSDLCNAYDDFNVTILRYFNPIGAHESGNIGEHPNGIPNNLFPYLTKVAIGEYPYLKVYGCDYPTSDGSGVRDYI
HVVDLAEAHVKALSKNSESTGLKIYNLGTGKGYSVLEVIEAFEKITGIKIPYKIMPRRDGDVAECWSDSTKANDKLEWKA
NRELYDMIRDAWNWQSKNPHGYDNT

Sequences:

>Translated_345_residues
MLMEPYMSILVTGGCGYIGVHTIYTLISQGYDVIVLDNLTNSSIESLERVKLMTNHNIPFYKGDVGNKKILVDIFNEHQI
KAVMHFAGLKSVSESIKKPIEYYSSNVMQTLSLISTMIEYNVKSFIFSSSATVYGKPKLCPINETHPIGKTTNPYGTSKL
MMELMLSDLCNAYDDFNVTILRYFNPIGAHESGNIGEHPNGIPNNLFPYLTKVAIGEYPYLKVYGCDYPTSDGSGVRDYI
HVVDLAEAHVKALSKNSESTGLKIYNLGTGKGYSVLEVIEAFEKITGIKIPYKIMPRRDGDVAECWSDSTKANDKLEWKA
NRELYDMIRDAWNWQSKNPHGYDNT
>Mature_345_residues
MLMEPYMSILVTGGCGYIGVHTIYTLISQGYDVIVLDNLTNSSIESLERVKLMTNHNIPFYKGDVGNKKILVDIFNEHQI
KAVMHFAGLKSVSESIKKPIEYYSSNVMQTLSLISTMIEYNVKSFIFSSSATVYGKPKLCPINETHPIGKTTNPYGTSKL
MMELMLSDLCNAYDDFNVTILRYFNPIGAHESGNIGEHPNGIPNNLFPYLTKVAIGEYPYLKVYGCDYPTSDGSGVRDYI
HVVDLAEAHVKALSKNSESTGLKIYNLGTGKGYSVLEVIEAFEKITGIKIPYKIMPRRDGDVAECWSDSTKANDKLEWKA
NRELYDMIRDAWNWQSKNPHGYDNT

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=340, Percent_Identity=50.8823529411765, Blast_Score=369, Evalue=1e-102,
Organism=Homo sapiens, GI56118217, Length=340, Percent_Identity=50.8823529411765, Blast_Score=369, Evalue=1e-102,
Organism=Homo sapiens, GI189083684, Length=340, Percent_Identity=50.8823529411765, Blast_Score=369, Evalue=1e-102,
Organism=Homo sapiens, GI7657641, Length=273, Percent_Identity=28.5714285714286, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI42516563, Length=319, Percent_Identity=24.7648902821317, Blast_Score=73, Evalue=4e-13,
Organism=Escherichia coli, GI1786974, Length=336, Percent_Identity=51.1904761904762, Blast_Score=370, Evalue=1e-104,
Organism=Escherichia coli, GI1788353, Length=367, Percent_Identity=26.4305177111717, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI48994969, Length=286, Percent_Identity=27.2727272727273, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1790049, Length=277, Percent_Identity=24.9097472924188, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71982035, Length=345, Percent_Identity=49.2753623188406, Blast_Score=349, Evalue=2e-96,
Organism=Caenorhabditis elegans, GI71982038, Length=347, Percent_Identity=48.9913544668588, Blast_Score=348, Evalue=2e-96,
Organism=Caenorhabditis elegans, GI17568069, Length=268, Percent_Identity=25.3731343283582, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI115532424, Length=344, Percent_Identity=24.7093023255814, Blast_Score=69, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6319493, Length=343, Percent_Identity=48.3965014577259, Blast_Score=332, Evalue=7e-92,
Organism=Drosophila melanogaster, GI19923002, Length=345, Percent_Identity=51.5942028985507, Blast_Score=374, Evalue=1e-104,
Organism=Drosophila melanogaster, GI21356223, Length=316, Percent_Identity=25.3164556962025, Blast_Score=72, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 38757; Mature: 38757

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLMEPYMSILVTGGCGYIGVHTIYTLISQGYDVIVLDNLTNSSIESLERVKLMTNHNIPF
CCCCCCCCEEEECCCCHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCE
YKGDVGNKKILVDIFNEHQIKAVMHFAGLKSVSESIKKPIEYYSSNVMQTLSLISTMIEY
EECCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NVKSFIFSSSATVYGKPKLCPINETHPIGKTTNPYGTSKLMMELMLSDLCNAYDDFNVTI
HHHHHEEECCCEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEE
LRYFNPIGAHESGNIGEHPNGIPNNLFPYLTKVAIGEYPYLKVYGCDYPTSDGSGVRDYI
EEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHH
HVVDLAEAHVKALSKNSESTGLKIYNLGTGKGYSVLEVIEAFEKITGIKIPYKIMPRRDG
HHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCEEECCCCCC
DVAECWSDSTKANDKLEWKANRELYDMIRDAWNWQSKNPHGYDNT
CHHHHHCCCCCCCCCEEECCCHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MLMEPYMSILVTGGCGYIGVHTIYTLISQGYDVIVLDNLTNSSIESLERVKLMTNHNIPF
CCCCCCCCEEEECCCCHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCE
YKGDVGNKKILVDIFNEHQIKAVMHFAGLKSVSESIKKPIEYYSSNVMQTLSLISTMIEY
EECCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NVKSFIFSSSATVYGKPKLCPINETHPIGKTTNPYGTSKLMMELMLSDLCNAYDDFNVTI
HHHHHEEECCCEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEE
LRYFNPIGAHESGNIGEHPNGIPNNLFPYLTKVAIGEYPYLKVYGCDYPTSDGSGVRDYI
EEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHH
HVVDLAEAHVKALSKNSESTGLKIYNLGTGKGYSVLEVIEAFEKITGIKIPYKIMPRRDG
HHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCEEECCCCCC
DVAECWSDSTKANDKLEWKANRELYDMIRDAWNWQSKNPHGYDNT
CHHHHHCCCCCCCCCEEECCCHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]