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The map label for this gene is int [H]

Identifier: 218689970

GI number: 218689970

Start: 2164318

End: 2165580

Strand: Direct

Name: int [H]

Synonym: ECED1_2243

Alternate gene names: 218689970

Gene position: 2164318-2165580 (Clockwise)

Preceding gene: 218689969

Following gene: 218689975

Centisome position: 41.55

GC content: 52.57

Gene sequence:

>1263_bases
ATGTCCCTTACCGACGCGAAAATCCGCACTCTCAAACCTTCTGATAAACCCTTTAAAGTCTCCGATTCCCACGGTCTGTA
TCTGCTGGTCAAGCCGGGTGGCTCACGTCACTGGTATCTCAAGTACCGTATTAACGGTAAAGAATCGCGCATTGCGCTGG
GTGCCTATCCTGCCGTCTCCCTCTCTGATGCGCGACAGCAGCGTGAAGGTGTCCGTAAAATGCTGGCGCTGAATATCAAC
CCGGTACAGCAGCGGGCTGCTGAACGTGGCTCACGAACACCGGATAAAGTTTTTAAAAACGTGGCGCTGGCGTGGCATAA
AAGTAACCGGAAATGGTCGCAGAACACCGCTGACCGTCTGCTTGCCAGCCTGAACAATCACATCTTTCCGGTCATTGGCA
ACCTGCCTGTATCAGAACTTAAACCCCGTCATTTCATTGACCTGCTGAAAAGGATCGAGGAAAAAGGTCTGCTGGAAGTT
GCGTCCCGCACGCGGCAGCACCTGAGTAACATAATGCGCCATGCGGTTCATCAGGGGTTAATCGATACGAACCCGGCAGC
AAATCTTGGCGGCGTGACCACACCTCCTGTCAGACGGCACTATCCTGCCCTGCCACTGGAGCGGCTGCCTGAACTGCTTG
AACGTATTGGGGCATATCATCAGGGTCGTGAACTGACGCGGTTGGCCGTCCTGCTGATGCTGCATGTGTTCATTCGCTCC
AGTGAACTGCGTTTCGCCCGCTGGTCAGAGATTGATTTCACAAACCGAGTCTGGACGATACCCGCGACGCGAGAACCCAT
TATTGGAGTGCGTTATTCCGGCCGCGGGGCCAAAATGCGAATGTCGCATATCGTCCCCCTCTCAGAACAGTCCATCGCCA
TTCTGAAACAGATTAAGGATATCACCGGTAATAATGAACTGATCTTCCCCGGCGACCATAACCCGTATAAGCCAATGTGT
GAAAACACGGTCAATAAGGCACTGCGGGTGATGGGCTACGACACGAAAAAGGATATCTGCGGTCACGGCTTCCGGGCAAT
GGCATGCAGTGCGCTGATGGAATCGGGTTTATGGGCAAAGGACGCAGTAGAACGCCAGATGAGTCATCAGGAGCGCAATA
CCGTGCGCATGGCTTATATTCATAAGGCAGAGCACCTAGAAGCCCGCAAAGCGATGATGCAGTGGTGGTCGGATTATCTG
GAAGCATGCCGAGAATCTTATGCACCGCCTTATACAATTGGTAAAAATAAGTTTATCCCATAG

Upstream 100 bases:

>100_bases
GAAAACTCTTCCCGGTGCATTTTGATTTTACCCTCCGCATCGGGAAAAATTGGTGGTCAAATCTGGGGTCAGGTTAGTTC
GATAATGGAGCGACCCCCAT

Downstream 100 bases:

>100_bases
TATACTAACGAATCCCACACTCTGGCAAATTACCACCACCTCTACAGGAGGTGGTTCTATATAGACTTTTATCAACTTCA
TGACGAAAAACACCTATTTT

Product: integrase

Products: NA

Alternate protein names: Int(P4) [H]

Number of amino acids: Translated: 420; Mature: 419

Protein sequence:

>420_residues
MSLTDAKIRTLKPSDKPFKVSDSHGLYLLVKPGGSRHWYLKYRINGKESRIALGAYPAVSLSDARQQREGVRKMLALNIN
PVQQRAAERGSRTPDKVFKNVALAWHKSNRKWSQNTADRLLASLNNHIFPVIGNLPVSELKPRHFIDLLKRIEEKGLLEV
ASRTRQHLSNIMRHAVHQGLIDTNPAANLGGVTTPPVRRHYPALPLERLPELLERIGAYHQGRELTRLAVLLMLHVFIRS
SELRFARWSEIDFTNRVWTIPATREPIIGVRYSGRGAKMRMSHIVPLSEQSIAILKQIKDITGNNELIFPGDHNPYKPMC
ENTVNKALRVMGYDTKKDICGHGFRAMACSALMESGLWAKDAVERQMSHQERNTVRMAYIHKAEHLEARKAMMQWWSDYL
EACRESYAPPYTIGKNKFIP

Sequences:

>Translated_420_residues
MSLTDAKIRTLKPSDKPFKVSDSHGLYLLVKPGGSRHWYLKYRINGKESRIALGAYPAVSLSDARQQREGVRKMLALNIN
PVQQRAAERGSRTPDKVFKNVALAWHKSNRKWSQNTADRLLASLNNHIFPVIGNLPVSELKPRHFIDLLKRIEEKGLLEV
ASRTRQHLSNIMRHAVHQGLIDTNPAANLGGVTTPPVRRHYPALPLERLPELLERIGAYHQGRELTRLAVLLMLHVFIRS
SELRFARWSEIDFTNRVWTIPATREPIIGVRYSGRGAKMRMSHIVPLSEQSIAILKQIKDITGNNELIFPGDHNPYKPMC
ENTVNKALRVMGYDTKKDICGHGFRAMACSALMESGLWAKDAVERQMSHQERNTVRMAYIHKAEHLEARKAMMQWWSDYL
EACRESYAPPYTIGKNKFIP
>Mature_419_residues
SLTDAKIRTLKPSDKPFKVSDSHGLYLLVKPGGSRHWYLKYRINGKESRIALGAYPAVSLSDARQQREGVRKMLALNINP
VQQRAAERGSRTPDKVFKNVALAWHKSNRKWSQNTADRLLASLNNHIFPVIGNLPVSELKPRHFIDLLKRIEEKGLLEVA
SRTRQHLSNIMRHAVHQGLIDTNPAANLGGVTTPPVRRHYPALPLERLPELLERIGAYHQGRELTRLAVLLMLHVFIRSS
ELRFARWSEIDFTNRVWTIPATREPIIGVRYSGRGAKMRMSHIVPLSEQSIAILKQIKDITGNNELIFPGDHNPYKPMCE
NTVNKALRVMGYDTKKDICGHGFRAMACSALMESGLWAKDAVERQMSHQERNTVRMAYIHKAEHLEARKAMMQWWSDYLE
ACRESYAPPYTIGKNKFIP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI1788974, Length=406, Percent_Identity=33.2512315270936, Blast_Score=237, Evalue=1e-63,
Organism=Escherichia coli, GI1788690, Length=401, Percent_Identity=30.9226932668329, Blast_Score=236, Evalue=2e-63,
Organism=Escherichia coli, GI145693166, Length=411, Percent_Identity=31.6301703163017, Blast_Score=194, Evalue=1e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 47984; Mature: 47853

Theoretical pI: Translated: 10.61; Mature: 10.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLTDAKIRTLKPSDKPFKVSDSHGLYLLVKPGGSRHWYLKYRINGKESRIALGAYPAVS
CCCCCCHHEEECCCCCCEEEECCCCEEEEEECCCCEEEEEEEEECCCCCEEEEECCCCCC
LSDARQQREGVRKMLALNINPVQQRAAERGSRTPDKVFKNVALAWHKSNRKWSQNTADRL
HHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHH
LASLNNHIFPVIGNLPVSELKPRHFIDLLKRIEEKGLLEVASRTRQHLSNIMRHAVHQGL
HHHHCCCEEEEECCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
IDTNPAANLGGVTTPPVRRHYPALPLERLPELLERIGAYHQGRELTRLAVLLMLHVFIRS
CCCCCCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHC
SELRFARWSEIDFTNRVWTIPATREPIIGVRYSGRGAKMRMSHIVPLSEQSIAILKQIKD
CCCCEEECCCCCCCCCEEECCCCCCCEEEEEECCCCCEEEHHHCCCCCCHHHHHHHHHHH
ITGNNELIFPGDHNPYKPMCENTVNKALRVMGYDTKKDICGHGFRAMACSALMESGLWAK
CCCCCCEEECCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHCCCCHH
DAVERQMSHQERNTVRMAYIHKAEHLEARKAMMQWWSDYLEACRESYAPPYTIGKNKFIP
HHHHHHHHHHHHCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCC
>Mature Secondary Structure 
SLTDAKIRTLKPSDKPFKVSDSHGLYLLVKPGGSRHWYLKYRINGKESRIALGAYPAVS
CCCCCHHEEECCCCCCEEEECCCCEEEEEECCCCEEEEEEEEECCCCCEEEEECCCCCC
LSDARQQREGVRKMLALNINPVQQRAAERGSRTPDKVFKNVALAWHKSNRKWSQNTADRL
HHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHH
LASLNNHIFPVIGNLPVSELKPRHFIDLLKRIEEKGLLEVASRTRQHLSNIMRHAVHQGL
HHHHCCCEEEEECCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
IDTNPAANLGGVTTPPVRRHYPALPLERLPELLERIGAYHQGRELTRLAVLLMLHVFIRS
CCCCCCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHC
SELRFARWSEIDFTNRVWTIPATREPIIGVRYSGRGAKMRMSHIVPLSEQSIAILKQIKD
CCCCEEECCCCCCCCCEEECCCCCCCEEEEEECCCCCEEEHHHCCCCCCHHHHHHHHHHH
ITGNNELIFPGDHNPYKPMCENTVNKALRVMGYDTKKDICGHGFRAMACSALMESGLWAK
CCCCCCEEECCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHCCCCHH
DAVERQMSHQERNTVRMAYIHKAEHLEARKAMMQWWSDYLEACRESYAPPYTIGKNKFIP
HHHHHHHHHHHHCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503 [H]