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The map label for this gene is fliD [H]

Identifier: 218689917

GI number: 218689917

Start: 2120834

End: 2122324

Strand: Direct

Name: fliD [H]

Synonym: ECED1_2189

Alternate gene names: 218689917

Gene position: 2120834-2122324 (Clockwise)

Preceding gene: 218689908

Following gene: 218689918

Centisome position: 40.71

GC content: 43.46

Gene sequence:

>1491_bases
GTGAATCAACTATTAAACTTTGCGCACAAATTGCCGATAACCCGCTTATCTACTGTTTGCAATCAAAAGGAATTAGGTAT
GGCTTCATTTACATCTCTTGGCGTTGGTTCGAATCTGCCGCTGGATACATTGCTAAACAACCTGACCATCGCTGAAAAAA
AACGCTTAAACCCAATTACTCAGCAACAGAGTGACAACACCGCACGTCTGACAGCCTATGGCACATTAAAAAGTGCATTA
GAAAAATTCCAGACTGCAAATACTGCGTTAAATAAAGCCGATCTGTTCAAAAGCACTACCGTTACCAGTAGCAATGAAGA
CCTTAAAGTTTCCACCGAAGCAGGTGCTGCCCCCGGTATCTATACCATCAGCGTAACCCAACTGGCGCAGGCGCAATCTT
TACGAACTGATTCCCCGACAATCATTGCATCAACAAAAGATGCACTGGGTGATGAGTCATCAGATACACGCACAATAAAA
ATTACCCAAGACGGCCGTAAAGAGCCGCTGGAAATCAAGCTCAATAAAGATCAGACGTCATTGGATGAGATCAGCAAAAC
CATTAACGATGCCGATAGTGGAATTTCCGCTAGTATCGTTAAAGTCAAAGATGGTGACTATCAATTGGTATTGACCGCCA
GTGAAGGTCTGGCCAATAAAATGACCATATCTGTTGAGGGTGACAGTAAATTAAATGATCTGCTGGCTTATGACAGCAAG
ACCAACACCGGGAATATGAAGGAACTGGTTAACGCGCAAAATGCACAGCTAAACGTTAACGGTATCGATATTGAACGTTC
AAGTAACAAAATTACCGATGCTCCTCAGGGAGTGACTCTCGATTTGACCAAAAAAGTCACTGACGTCCGGGTCACGGTGA
CAAAAAGCAACGATAAAGCAACCGAAGCAATTAAAGGCTGGGTGGATTCATATAACTCCCTCATTGACACCTTTAACACC
CTGACAAAATATAAAGAAGTAGACCCAGGTGCTGAAGCACAAGATAAAAATAATGGTGCACTTCTCGGAGACAGCGTTGT
ACGTACAATTCAAAGCGGCATCCGCGCACAATTTGCAAACGGAGCCAGCGACGGTGCCTTCAAAACATTAAACGAGATCG
GGATTAAGCAGGACGGCACGACGGGTAAGCTGAAAATTGATGATGATAAACTCAAAAAAGTCCTGAATGAAAATACAGCA
TCCGTACGTGAATTGCTGGTAGGCGATGGTAAAGAAACAGGAATTACCACCAAAATTGCCACCGAGGTAAAAGGTTACCT
TGCCGATGATGGCATTATTGATAGCGCACAGGACAGTATTAACGCCACACTGAAAAAACTAACCAAACAGTATCTATCCG
TCAGTGCCAGCATTGATGACACCGTGGCGCGTTACACTGCACAGTTTACGCAATTAGATACCATGATGAGCAAACTGAAT
AACACCAGTACCTATCTCAGCCAACAATTTACTGCAATGAGTAATTCCTGA

Upstream 100 bases:

>100_bases
CACCTGAATTTCGAACTTTAGAAAATTTTAGTTTCTCTCCTGTTTTTTCTTAACGGCTGAAATATCCGTAATATACAACT
CTACTCTGCGCATCATCTTC

Downstream 100 bases:

>100_bases
TCACGGAGGTCAGCATGTATACCGCGAGCGGCTCAAAAGCCTATGCACAAATTGGCGTCGAAAGCGCCGTAATGAGCGCC
AGCCAGCAGCAGCTGGTCAC

Product: flagellar capping protein

Products: NA

Alternate protein names: HAP2; Filament cap protein [H]

Number of amino acids: Translated: 496; Mature: 496

Protein sequence:

>496_residues
MNQLLNFAHKLPITRLSTVCNQKELGMASFTSLGVGSNLPLDTLLNNLTIAEKKRLNPITQQQSDNTARLTAYGTLKSAL
EKFQTANTALNKADLFKSTTVTSSNEDLKVSTEAGAAPGIYTISVTQLAQAQSLRTDSPTIIASTKDALGDESSDTRTIK
ITQDGRKEPLEIKLNKDQTSLDEISKTINDADSGISASIVKVKDGDYQLVLTASEGLANKMTISVEGDSKLNDLLAYDSK
TNTGNMKELVNAQNAQLNVNGIDIERSSNKITDAPQGVTLDLTKKVTDVRVTVTKSNDKATEAIKGWVDSYNSLIDTFNT
LTKYKEVDPGAEAQDKNNGALLGDSVVRTIQSGIRAQFANGASDGAFKTLNEIGIKQDGTTGKLKIDDDKLKKVLNENTA
SVRELLVGDGKETGITTKIATEVKGYLADDGIIDSAQDSINATLKKLTKQYLSVSASIDDTVARYTAQFTQLDTMMSKLN
NTSTYLSQQFTAMSNS

Sequences:

>Translated_496_residues
MNQLLNFAHKLPITRLSTVCNQKELGMASFTSLGVGSNLPLDTLLNNLTIAEKKRLNPITQQQSDNTARLTAYGTLKSAL
EKFQTANTALNKADLFKSTTVTSSNEDLKVSTEAGAAPGIYTISVTQLAQAQSLRTDSPTIIASTKDALGDESSDTRTIK
ITQDGRKEPLEIKLNKDQTSLDEISKTINDADSGISASIVKVKDGDYQLVLTASEGLANKMTISVEGDSKLNDLLAYDSK
TNTGNMKELVNAQNAQLNVNGIDIERSSNKITDAPQGVTLDLTKKVTDVRVTVTKSNDKATEAIKGWVDSYNSLIDTFNT
LTKYKEVDPGAEAQDKNNGALLGDSVVRTIQSGIRAQFANGASDGAFKTLNEIGIKQDGTTGKLKIDDDKLKKVLNENTA
SVRELLVGDGKETGITTKIATEVKGYLADDGIIDSAQDSINATLKKLTKQYLSVSASIDDTVARYTAQFTQLDTMMSKLN
NTSTYLSQQFTAMSNS
>Mature_496_residues
MNQLLNFAHKLPITRLSTVCNQKELGMASFTSLGVGSNLPLDTLLNNLTIAEKKRLNPITQQQSDNTARLTAYGTLKSAL
EKFQTANTALNKADLFKSTTVTSSNEDLKVSTEAGAAPGIYTISVTQLAQAQSLRTDSPTIIASTKDALGDESSDTRTIK
ITQDGRKEPLEIKLNKDQTSLDEISKTINDADSGISASIVKVKDGDYQLVLTASEGLANKMTISVEGDSKLNDLLAYDSK
TNTGNMKELVNAQNAQLNVNGIDIERSSNKITDAPQGVTLDLTKKVTDVRVTVTKSNDKATEAIKGWVDSYNSLIDTFNT
LTKYKEVDPGAEAQDKNNGALLGDSVVRTIQSGIRAQFANGASDGAFKTLNEIGIKQDGTTGKLKIDDDKLKKVLNENTA
SVRELLVGDGKETGITTKIATEVKGYLADDGIIDSAQDSINATLKKLTKQYLSVSASIDDTVARYTAQFTQLDTMMSKLN
NTSTYLSQQFTAMSNS

Specific function: Required for the morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the

COG id: COG1345

COG function: function code N; Flagellar capping protein

Gene ontology:

Cell location: Secreted. Bacterial flagellum [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fliD family [H]

Homologues:

Organism=Escherichia coli, GI1788233, Length=472, Percent_Identity=49.5762711864407, Blast_Score=394, Evalue=1e-111,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010810
- InterPro:   IPR010809
- InterPro:   IPR003481 [H]

Pfam domain/function: PF07196 Flagellin_IN; PF07195 FliD_C; PF02465 FliD_N [H]

EC number: NA

Molecular weight: Translated: 53385; Mature: 53385

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQLLNFAHKLPITRLSTVCNQKELGMASFTSLGVGSNLPLDTLLNNLTIAEKKRLNPIT
CCHHHHHHHHCCHHHHHHHHCHHHCCCHHHHHCCCCCCCCHHHHHHCCCHHHHHHCCCCH
QQQSDNTARLTAYGTLKSALEKFQTANTALNKADLFKSTTVTSSNEDLKVSTEAGAAPGI
HCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCEECCCCCCEEEEECCCCCCCE
YTISVTQLAQAQSLRTDSPTIIASTKDALGDESSDTRTIKITQDGRKEPLEIKLNKDQTS
EEEEHHHHHHHHHCCCCCCEEEEECHHHCCCCCCCCEEEEEECCCCCCCEEEEECCCCCH
LDEISKTINDADSGISASIVKVKDGDYQLVLTASEGLANKMTISVEGDSKLNDLLAYDSK
HHHHHHHHHHCCCCCEEEEEEEECCCEEEEEEECCCCCCEEEEEECCCCCHHHHHHCCCC
TNTGNMKELVNAQNAQLNVNGIDIERSSNKITDAPQGVTLDLTKKVTDVRVTVTKSNDKA
CCCCCHHHHHCCCCCEEEEEEEEEECCCCCCCCCCCCCEEEEECCEEEEEEEEECCCCHH
TEAIKGWVDSYNSLIDTFNTLTKYKEVDPGAEAQDKNNGALLGDSVVRTIQSGIRAQFAN
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHCC
GASDGAFKTLNEIGIKQDGTTGKLKIDDDKLKKVLNENTASVRELLVGDGKETGITTKIA
CCCCCHHHHHHHHCCCCCCCCCEEEECHHHHHHHHCCCHHHHHHHHHCCCCCCCCCHHHH
TEVKGYLADDGIIDSAQDSINATLKKLTKQYLSVSASIDDTVARYTAQFTQLDTMMSKLN
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHC
NTSTYLSQQFTAMSNS
CHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNQLLNFAHKLPITRLSTVCNQKELGMASFTSLGVGSNLPLDTLLNNLTIAEKKRLNPIT
CCHHHHHHHHCCHHHHHHHHCHHHCCCHHHHHCCCCCCCCHHHHHHCCCHHHHHHCCCCH
QQQSDNTARLTAYGTLKSALEKFQTANTALNKADLFKSTTVTSSNEDLKVSTEAGAAPGI
HCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCEECCCCCCEEEEECCCCCCCE
YTISVTQLAQAQSLRTDSPTIIASTKDALGDESSDTRTIKITQDGRKEPLEIKLNKDQTS
EEEEHHHHHHHHHCCCCCCEEEEECHHHCCCCCCCCEEEEEECCCCCCCEEEEECCCCCH
LDEISKTINDADSGISASIVKVKDGDYQLVLTASEGLANKMTISVEGDSKLNDLLAYDSK
HHHHHHHHHHCCCCCEEEEEEEECCCEEEEEEECCCCCCEEEEEECCCCCHHHHHHCCCC
TNTGNMKELVNAQNAQLNVNGIDIERSSNKITDAPQGVTLDLTKKVTDVRVTVTKSNDKA
CCCCCHHHHHCCCCCEEEEEEEEEECCCCCCCCCCCCCEEEEECCEEEEEEEEECCCCHH
TEAIKGWVDSYNSLIDTFNTLTKYKEVDPGAEAQDKNNGALLGDSVVRTIQSGIRAQFAN
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHCC
GASDGAFKTLNEIGIKQDGTTGKLKIDDDKLKKVLNENTASVRELLVGDGKETGITTKIA
CCCCCHHHHHHHHCCCCCCCCCEEEECHHHHHHHHCCCHHHHHHHHHCCCCCCCCCHHHH
TEVKGYLADDGIIDSAQDSINATLKKLTKQYLSVSASIDDTVARYTAQFTQLDTMMSKLN
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHC
NTSTYLSQQFTAMSNS
CHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2193164; 11677609; 1527488; 9878359; 11118149 [H]