Click here to switch to the map view.

The map label for this gene is prc [H]

Identifier: 218689767

GI number: 218689767

Start: 1981968

End: 1984016

Strand: Reverse

Name: prc [H]

Synonym: ECED1_2034

Alternate gene names: 218689767

Gene position: 1984016-1981968 (Counterclockwise)

Preceding gene: 218689768

Following gene: 218689766

Centisome position: 38.08

GC content: 50.41

Gene sequence:

>2049_bases
ATGAACATGTTTTTTAGGCTTACCGCGTTAGCTGGCCTGCTTGCAATAGCAGGCCAGACCTTCGCTGTAGAAGATATCAC
GCGTGCTGATCAAATTCCGGTATTAAAGGAAGAGACGCAGCATGCGACGGTGAGTGAGCGCGTAACGTCGCGCTTCACCC
GTTCTCATTATCGCCAGTTCGACCTCGATCAGGCATTTTCGGCCAAAATCTTTGACCGCTACCTGAATCTGCTCGATTAC
AGCCACAATGTGCTGCTGGCAAGCGATGTTGAACAGTTCGCGAAAAAGAAAACTGAGTTAGGCGATGAACTGCGTTCAGG
TAAACTCGACGTTTTCTACGATCTCTACAATCTGGCGCAAAAGCGCCGTTTTGAACGTTACCAGTACGCTTTGTCGGTAC
TGGAAAAGCCGATGGATTTCACCGGCAACGACACTTATAACCTTGACCGCAGCAAAGCGCCCTGGCCGAAAAACGAGGCT
GAGTTGAACGCGCTGTGGGACAGTAAAGTCAAATTCGACGAGTTAATCCTGAAGCTGACAGGAAAAACGGATAAGGAAAT
TCGTGAAACCCTGACTCGCCGCTACAAATTTGCCATTCGTCGTCTGGCGCAAACCAACAGCGAAGATGTTTTCTCGCTGG
CAATGACGGCGTTTGCGCGTGAAATCGACCCGCATACCAACTATCTTTCCCCGCGTAATACCGAACAGTTCAACACTGAA
ATGAGTTTGTCGCTGGAAGGTATTGGCGCAGTGCTGCAAATGGATGATGACTACACCGTTATCAATTCGATGGTGGCAGG
AGGTCCGGCAGCGAAGAGCAAAGCTATCAGCGTTGGTGACAAAATTGTCGGTGTTGGTCAAACAGGCAAGCCGATGGTTG
ACGTGATTGGCTGGCGTCTTGATGATGTGGTGGCCTTAATTAAAGGGCCTAAGGGCAGTAAGGTTCGTCTGGAAATTTTA
CCTGCTGGTAAAGGGACCAAGACCCGTACGGTAACGTTGACCCGTGAACGTATTCGTCTCGAAGACCGCGCGGTTAAAAT
GTCGGTGAAGACCGTCGGTAAAGAGAAAGTCGGCGTGCTGGATATTCCGGGCTTCTATGTGGGTTTGACAGACGATGTCA
AAGTGCAACTGCAGAAACTGGAAAAACAGAATGTCAGCAGTGTGATTATCGACCTGCGTAGCAATGGTGGTGGGGCGTTG
ACTGAAGCCGTATCGCTCTCCGGTCTGTTCATTCCATCCGGCCCGATTGTTCAGGTCCGCGATAACAACGGCAAGGTTCG
TGAAGACAGCGACACCGACGGACAGGTCTTCTATAAAGGCCCGCTGGTGGTGCTGGTTGACCGCTTCAGTGCTTCGGCTT
CAGAAATCTTTGCCGCGGCAATGCAGGATTACGGTCGTGCCCTGGTTGTGGGTGAACCGACATTTGGTAAAGGCACCGTT
CAGCAGTACCGTTCATTGAACCGTATTTACGATCAGATGTTACGTCCTGAATGGCCAGCGCTGGGTTCTGTGCAGTACAC
GATCCAGAAATTCTATCGCGTTAACGGCGGCAGTACGCAACGTAAAGGCGTAACGCCAGACATCATCATGCCGACGGGTA
ATGAAGAAACGGAAACGGGTGAGAAATTCGAAGATAACGCGCTGCCGTGGGATAGCATTGATGCCGCGACTTATGTGAAA
TCAGGAGATTTAACGGCCTTTGAACCGGAGCTGCTGAAGGAACATAATGCGCGTATCGCGAAAGATCCTGAGTTCCAGAA
CATCATGAAGGATATCGCGCGCTTCAACGCTATGAAGGACAAGCGCAATATCGTTTCTCTGAATTACGCTGTGCGTGAGA
AAGAGAATAATGAAGATGATGCGACGCGTCTGGCGCGTTTGAACGAACGCTTTAAACGCGAAGGTAAACCGGAGTTGAAG
AAACTGGATGATCTACCGAAAGATTACCAGGAGCCAGATCCTTATCTGGATGAGACGGTGAATATCGCACTCGATCTGGC
GAAGCTTGAAAAAGCCAGACCCGCGGAACAACCCGCTCCCGTCAAGTAA

Upstream 100 bases:

>100_bases
GAAATCACCAAAGACGGCGTCCGCGTCCAGCTGAATTCGGGTATGTCTTTGATTGTGCGCGCAGAACACCTGGTGTTCTG
AAACGGAGGCCGGGCCAGGC

Downstream 100 bases:

>100_bases
TATCAATCAGGCACAAGAAATTGTGCCTGATTTTTTAACAGCGGCAAGATGCCGTAAATCAGATGCTACAAAATGTAAAG
TTGTGTCTTTCTGGTGACTT

Product: carboxy-terminal protease

Products: NA

Alternate protein names: C-terminal-processing peptidase; PRC protein; Protease Re [H]

Number of amino acids: Translated: 682; Mature: 682

Protein sequence:

>682_residues
MNMFFRLTALAGLLAIAGQTFAVEDITRADQIPVLKEETQHATVSERVTSRFTRSHYRQFDLDQAFSAKIFDRYLNLLDY
SHNVLLASDVEQFAKKKTELGDELRSGKLDVFYDLYNLAQKRRFERYQYALSVLEKPMDFTGNDTYNLDRSKAPWPKNEA
ELNALWDSKVKFDELILKLTGKTDKEIRETLTRRYKFAIRRLAQTNSEDVFSLAMTAFAREIDPHTNYLSPRNTEQFNTE
MSLSLEGIGAVLQMDDDYTVINSMVAGGPAAKSKAISVGDKIVGVGQTGKPMVDVIGWRLDDVVALIKGPKGSKVRLEIL
PAGKGTKTRTVTLTRERIRLEDRAVKMSVKTVGKEKVGVLDIPGFYVGLTDDVKVQLQKLEKQNVSSVIIDLRSNGGGAL
TEAVSLSGLFIPSGPIVQVRDNNGKVREDSDTDGQVFYKGPLVVLVDRFSASASEIFAAAMQDYGRALVVGEPTFGKGTV
QQYRSLNRIYDQMLRPEWPALGSVQYTIQKFYRVNGGSTQRKGVTPDIIMPTGNEETETGEKFEDNALPWDSIDAATYVK
SGDLTAFEPELLKEHNARIAKDPEFQNIMKDIARFNAMKDKRNIVSLNYAVREKENNEDDATRLARLNERFKREGKPELK
KLDDLPKDYQEPDPYLDETVNIALDLAKLEKARPAEQPAPVK

Sequences:

>Translated_682_residues
MNMFFRLTALAGLLAIAGQTFAVEDITRADQIPVLKEETQHATVSERVTSRFTRSHYRQFDLDQAFSAKIFDRYLNLLDY
SHNVLLASDVEQFAKKKTELGDELRSGKLDVFYDLYNLAQKRRFERYQYALSVLEKPMDFTGNDTYNLDRSKAPWPKNEA
ELNALWDSKVKFDELILKLTGKTDKEIRETLTRRYKFAIRRLAQTNSEDVFSLAMTAFAREIDPHTNYLSPRNTEQFNTE
MSLSLEGIGAVLQMDDDYTVINSMVAGGPAAKSKAISVGDKIVGVGQTGKPMVDVIGWRLDDVVALIKGPKGSKVRLEIL
PAGKGTKTRTVTLTRERIRLEDRAVKMSVKTVGKEKVGVLDIPGFYVGLTDDVKVQLQKLEKQNVSSVIIDLRSNGGGAL
TEAVSLSGLFIPSGPIVQVRDNNGKVREDSDTDGQVFYKGPLVVLVDRFSASASEIFAAAMQDYGRALVVGEPTFGKGTV
QQYRSLNRIYDQMLRPEWPALGSVQYTIQKFYRVNGGSTQRKGVTPDIIMPTGNEETETGEKFEDNALPWDSIDAATYVK
SGDLTAFEPELLKEHNARIAKDPEFQNIMKDIARFNAMKDKRNIVSLNYAVREKENNEDDATRLARLNERFKREGKPELK
KLDDLPKDYQEPDPYLDETVNIALDLAKLEKARPAEQPAPVK
>Mature_682_residues
MNMFFRLTALAGLLAIAGQTFAVEDITRADQIPVLKEETQHATVSERVTSRFTRSHYRQFDLDQAFSAKIFDRYLNLLDY
SHNVLLASDVEQFAKKKTELGDELRSGKLDVFYDLYNLAQKRRFERYQYALSVLEKPMDFTGNDTYNLDRSKAPWPKNEA
ELNALWDSKVKFDELILKLTGKTDKEIRETLTRRYKFAIRRLAQTNSEDVFSLAMTAFAREIDPHTNYLSPRNTEQFNTE
MSLSLEGIGAVLQMDDDYTVINSMVAGGPAAKSKAISVGDKIVGVGQTGKPMVDVIGWRLDDVVALIKGPKGSKVRLEIL
PAGKGTKTRTVTLTRERIRLEDRAVKMSVKTVGKEKVGVLDIPGFYVGLTDDVKVQLQKLEKQNVSSVIIDLRSNGGGAL
TEAVSLSGLFIPSGPIVQVRDNNGKVREDSDTDGQVFYKGPLVVLVDRFSASASEIFAAAMQDYGRALVVGEPTFGKGTV
QQYRSLNRIYDQMLRPEWPALGSVQYTIQKFYRVNGGSTQRKGVTPDIIMPTGNEETETGEKFEDNALPWDSIDAATYVK
SGDLTAFEPELLKEHNARIAKDPEFQNIMKDIARFNAMKDKRNIVSLNYAVREKENNEDDATRLARLNERFKREGKPELK
KLDDLPKDYQEPDPYLDETVNIALDLAKLEKARPAEQPAPVK

Specific function: Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3 (PBP3). May be involved in protection of the bacterium from thermal and osmotic stresses [H]

COG id: COG0793

COG function: function code M; Periplasmic protease

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Periplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1788134, Length=682, Percent_Identity=99.7067448680352, Blast_Score=1391, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR005151
- InterPro:   IPR004447
- InterPro:   IPR020992 [H]

Pfam domain/function: PF11818 DUF3340; PF00595 PDZ; PF03572 Peptidase_S41 [H]

EC number: =3.4.21.102 [H]

Molecular weight: Translated: 76706; Mature: 76706

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNMFFRLTALAGLLAIAGQTFAVEDITRADQIPVLKEETQHATVSERVTSRFTRSHYRQF
CCHHHHHHHHHHHHHHCCCCEEHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
DLDQAFSAKIFDRYLNLLDYSHNVLLASDVEQFAKKKTELGDELRSGKLDVFYDLYNLAQ
CCHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
KRRFERYQYALSVLEKPMDFTGNDTYNLDRSKAPWPKNEAELNALWDSKVKFDELILKLT
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCHHHHHHHHC
GKTDKEIRETLTRRYKFAIRRLAQTNSEDVFSLAMTAFAREIDPHTNYLSPRNTEQFNTE
CCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCE
MSLSLEGIGAVLQMDDDYTVINSMVAGGPAAKSKAISVGDKIVGVGQTGKPMVDVIGWRL
EEEEECCCCEEEEECCCHHHHHHHHCCCCCCCCCEEECCCEEEECCCCCCCHHHHHCCCH
DDVVALIKGPKGSKVRLEILPAGKGTKTRTVTLTRERIRLEDRAVKMSVKTVGKEKVGVL
HHHHHHHCCCCCCEEEEEEEECCCCCCEEEEEEEHHHHHHHHHHHEEHHHHCCCCCCCEE
DIPGFYVGLTDDVKVQLQKLEKQNVSSVIIDLRSNGGGALTEAVSLSGLFIPSGPIVQVR
ECCCEEEECCHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHCEEEECCCCEEEEE
DNNGKVREDSDTDGQVFYKGPLVVLVDRFSASASEIFAAAMQDYGRALVVGEPTFGKGTV
CCCCCCCCCCCCCCEEEEECCEEEEEECCCCCHHHHHHHHHHHHCCEEEEECCCCCCHHH
QQYRSLNRIYDQMLRPEWPALGSVQYTIQKFYRVNGGSTQRKGVTPDIIMPTGNEETETG
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCCCCCC
EKFEDNALPWDSIDAATYVKSGDLTAFEPELLKEHNARIAKDPEFQNIMKDIARFNAMKD
CCCCCCCCCCCCCCHHHEEECCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHC
KRNIVSLNYAVREKENNEDDATRLARLNERFKREGKPELKKLDDLPKDYQEPDPYLDETV
CCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHCCCCCCHHHHH
NIALDLAKLEKARPAEQPAPVK
HHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MNMFFRLTALAGLLAIAGQTFAVEDITRADQIPVLKEETQHATVSERVTSRFTRSHYRQF
CCHHHHHHHHHHHHHHCCCCEEHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
DLDQAFSAKIFDRYLNLLDYSHNVLLASDVEQFAKKKTELGDELRSGKLDVFYDLYNLAQ
CCHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
KRRFERYQYALSVLEKPMDFTGNDTYNLDRSKAPWPKNEAELNALWDSKVKFDELILKLT
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCHHHHHHHHC
GKTDKEIRETLTRRYKFAIRRLAQTNSEDVFSLAMTAFAREIDPHTNYLSPRNTEQFNTE
CCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCE
MSLSLEGIGAVLQMDDDYTVINSMVAGGPAAKSKAISVGDKIVGVGQTGKPMVDVIGWRL
EEEEECCCCEEEEECCCHHHHHHHHCCCCCCCCCEEECCCEEEECCCCCCCHHHHHCCCH
DDVVALIKGPKGSKVRLEILPAGKGTKTRTVTLTRERIRLEDRAVKMSVKTVGKEKVGVL
HHHHHHHCCCCCCEEEEEEEECCCCCCEEEEEEEHHHHHHHHHHHEEHHHHCCCCCCCEE
DIPGFYVGLTDDVKVQLQKLEKQNVSSVIIDLRSNGGGALTEAVSLSGLFIPSGPIVQVR
ECCCEEEECCHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHCEEEECCCCEEEEE
DNNGKVREDSDTDGQVFYKGPLVVLVDRFSASASEIFAAAMQDYGRALVVGEPTFGKGTV
CCCCCCCCCCCCCCEEEEECCEEEEEECCCCCHHHHHHHHHHHHCCEEEEECCCCCCHHH
QQYRSLNRIYDQMLRPEWPALGSVQYTIQKFYRVNGGSTQRKGVTPDIIMPTGNEETETG
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCCCCCC
EKFEDNALPWDSIDAATYVKSGDLTAFEPELLKEHNARIAKDPEFQNIMKDIARFNAMKD
CCCCCCCCCCCCCCHHHEEECCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHC
KRNIVSLNYAVREKENNEDDATRLARLNERFKREGKPELKKLDDLPKDYQEPDPYLDETV
CCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHCCCCCCHHHHH
NIALDLAKLEKARPAEQPAPVK
HHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1856173; 1729701; 9097040; 9278503; 1447154; 10049386; 7499412; 8576225 [H]