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The map label for this gene is sufB [H]

Identifier: 218689625

GI number: 218689625

Start: 1840016

End: 1841503

Strand: Reverse

Name: sufB [H]

Synonym: ECED1_1882

Alternate gene names: 218689625

Gene position: 1841503-1840016 (Counterclockwise)

Preceding gene: 218689626

Following gene: 218689624

Centisome position: 35.35

GC content: 51.61

Gene sequence:

>1488_bases
ATGTCTCGTAATACTGAAGCAACTGACGATGTCAAAACCTGGACCGGCGGCCCGCTGAATTATAAAGAAGGATTCTTCAC
CCAGTTAGCCACCGATGAGCTGGCAAAGGGGATAAACGAAGAGGTGGTGCGCGCAATTTCGGCGAAGCGTAATGAGCCGG
AGTGGATGCTGGAGTTTCGTCTCAACGCCTATCACGCATGGCTGGAGATGGAAGAACCGCACTGGTTGAAAGCGCACTAC
GACAAGCTGAATTATCAGGATTACAGCTACTACTCGGCACCATCGTGCGGTAATTGTGACGACAACTGCGCGTCTGAACC
CGGCGCGGTGCAGCAAACTGGCGCGAACGCCTTTTTAAGTAAAGAGGTGGAGGCGGCGTTTGAGCAGTTGGGCGTTCCCG
TGCGGGAAGGCAAAGAGGTGGCAGTGGATGCCATTTTCGACTCTGTTTCGGTTGCCACTACTTATCGCAAAAAACTGGCG
GAGCAGGGAATTATTTTTTGTTCCTTTGGCGAGGCGATCCACGATCACCCGGAACTGGTGCGTAAATATCTCGGCACCGT
GGTGCCGGGGAATGACAACTTCTTTGCCGCACTTAATGCGGCGGTAGCCTCTGACGGTACGTTTATTTATGTGCCTAAAG
GCGTGCGTTGCCCGATGGAACTTTCCACCTATTTTCGCATTAACGCGGAAAAAACCGGGCAGTTTGAGCGCACCATTCTG
GTGGCCGACGAAGACAGCTACGTTAGCTACATTGAAGGCTGTTCCGCTCCGGTGCGTGACAGCTATCAGTTACACGCGGC
GGTGGTGGAAGTCATCATCCATAAAAACGCCGAGGTGAAATATTCCACGGTACAAAACTGGTTCCCTGGCGATAACAACA
CCGGCGGTATTCTCAACTTCGTCACCAAGCGTGCTTTGTGCGAAGGCGAAAACAGCAAAATGTCATGGACGCAATCAGAA
ACCGGGTCAGCGATTACGTGGAAATATCCCAGCTGCATTTTGCGCGGCGATAACTCCATTGGTGAGTTTTACTCAGTGGC
GCTGACCAGCGGTCATCAGCAAGCGGATACCGGCACCAAGATGATCCACATCGGTAAAAACACCAAATCGACCATTATCT
CGAAAGGGATCTCTGCCGGACATAGTCAGAACAGTTATCGCGGCTTAGTGAAAATCATGCCGACGGCAACCAATGCGCGC
AATTTCACTCAGTGCGACTCAATGTTGATTGGCGCTAATTGTGGGGCGCATACCTTCCCGTATGTCGAATGTCGCAATAA
CAGCGCTCAGCTGGAGCACGAGGCAACGACATCACGTATTGGTGAAGATCAACTGTTTTACTGCCTGCAACGCGGGATCA
GCGAAGAAGATGCCATCTCGATGATTGTTAACGGTTTTTGCAAAGACGTGTTCTCGGAACTGCCGCTGGAATTTGCCGTT
GAAGCACAAAAACTCCTCGCCATCAGTCTTGAACACAGCGTCGGATAA

Upstream 100 bases:

>100_bases
ATTTCGTTCGCGAAGGACTTAATCAGATATTCAAATTTCACAACCCTAAAGCCCAGAATGAATGTGGCTGTGGCGAAAGC
TTTGGGGTATAGGCGGTACT

Downstream 100 bases:

>100_bases
GGAATAAACATGTTAAGTATTAAAGATTTACACGTCAGCGTGGAAGATAAAGCTATCCTGCGTGGATTAAGCCTCGACGT
TCGTCCCGGCGAAGTTCACG

Product: cysteine desulfurase activator complex subunit SufB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 495; Mature: 494

Protein sequence:

>495_residues
MSRNTEATDDVKTWTGGPLNYKEGFFTQLATDELAKGINEEVVRAISAKRNEPEWMLEFRLNAYHAWLEMEEPHWLKAHY
DKLNYQDYSYYSAPSCGNCDDNCASEPGAVQQTGANAFLSKEVEAAFEQLGVPVREGKEVAVDAIFDSVSVATTYRKKLA
EQGIIFCSFGEAIHDHPELVRKYLGTVVPGNDNFFAALNAAVASDGTFIYVPKGVRCPMELSTYFRINAEKTGQFERTIL
VADEDSYVSYIEGCSAPVRDSYQLHAAVVEVIIHKNAEVKYSTVQNWFPGDNNTGGILNFVTKRALCEGENSKMSWTQSE
TGSAITWKYPSCILRGDNSIGEFYSVALTSGHQQADTGTKMIHIGKNTKSTIISKGISAGHSQNSYRGLVKIMPTATNAR
NFTQCDSMLIGANCGAHTFPYVECRNNSAQLEHEATTSRIGEDQLFYCLQRGISEEDAISMIVNGFCKDVFSELPLEFAV
EAQKLLAISLEHSVG

Sequences:

>Translated_495_residues
MSRNTEATDDVKTWTGGPLNYKEGFFTQLATDELAKGINEEVVRAISAKRNEPEWMLEFRLNAYHAWLEMEEPHWLKAHY
DKLNYQDYSYYSAPSCGNCDDNCASEPGAVQQTGANAFLSKEVEAAFEQLGVPVREGKEVAVDAIFDSVSVATTYRKKLA
EQGIIFCSFGEAIHDHPELVRKYLGTVVPGNDNFFAALNAAVASDGTFIYVPKGVRCPMELSTYFRINAEKTGQFERTIL
VADEDSYVSYIEGCSAPVRDSYQLHAAVVEVIIHKNAEVKYSTVQNWFPGDNNTGGILNFVTKRALCEGENSKMSWTQSE
TGSAITWKYPSCILRGDNSIGEFYSVALTSGHQQADTGTKMIHIGKNTKSTIISKGISAGHSQNSYRGLVKIMPTATNAR
NFTQCDSMLIGANCGAHTFPYVECRNNSAQLEHEATTSRIGEDQLFYCLQRGISEEDAISMIVNGFCKDVFSELPLEFAV
EAQKLLAISLEHSVG
>Mature_494_residues
SRNTEATDDVKTWTGGPLNYKEGFFTQLATDELAKGINEEVVRAISAKRNEPEWMLEFRLNAYHAWLEMEEPHWLKAHYD
KLNYQDYSYYSAPSCGNCDDNCASEPGAVQQTGANAFLSKEVEAAFEQLGVPVREGKEVAVDAIFDSVSVATTYRKKLAE
QGIIFCSFGEAIHDHPELVRKYLGTVVPGNDNFFAALNAAVASDGTFIYVPKGVRCPMELSTYFRINAEKTGQFERTILV
ADEDSYVSYIEGCSAPVRDSYQLHAAVVEVIIHKNAEVKYSTVQNWFPGDNNTGGILNFVTKRALCEGENSKMSWTQSET
GSAITWKYPSCILRGDNSIGEFYSVALTSGHQQADTGTKMIHIGKNTKSTIISKGISAGHSQNSYRGLVKIMPTATNARN
FTQCDSMLIGANCGAHTFPYVECRNNSAQLEHEATTSRIGEDQLFYCLQRGISEEDAISMIVNGFCKDVFSELPLEFAVE
AQKLLAISLEHSVG

Specific function: The sufBCD complex acts synergistically with sufE to stimulate the cysteine desulfurase activity of sufS. The sufBCD complex contributes to the assembly or repair of oxygen-labile iron-sulfur clusters under oxidative stress. May facilitate iron uptake fro

COG id: COG0719

COG function: function code O; ABC-type transport system involved in Fe-S cluster assembly, permease component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0051 (ycf24) family [H]

Homologues:

Organism=Escherichia coli, GI87081955, Length=495, Percent_Identity=99.3939393939394, Blast_Score=1033, Evalue=0.0,
Organism=Escherichia coli, GI1787971, Length=153, Percent_Identity=26.797385620915, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010231
- InterPro:   IPR000825 [H]

Pfam domain/function: PF01458 UPF0051 [H]

EC number: NA

Molecular weight: Translated: 54739; Mature: 54607

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRNTEATDDVKTWTGGPLNYKEGFFTQLATDELAKGINEEVVRAISAKRNEPEWMLEFR
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEEEE
LNAYHAWLEMEEPHWLKAHYDKLNYQDYSYYSAPSCGNCDDNCASEPGAVQQTGANAFLS
ECEEEEEEECCCCCHHHHHHHCCCCCCCCEECCCCCCCCCCCCCCCCCCCHHCCCHHHHH
KEVEAAFEQLGVPVREGKEVAVDAIFDSVSVATTYRKKLAEQGIIFCSFGEAIHDHPELV
HHHHHHHHHHCCCHHCCCCEEHHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHCCCHHHH
RKYLGTVVPGNDNFFAALNAAVASDGTFIYVPKGVRCPMELSTYFRINAEKTGQFERTIL
HHHHCEECCCCCCEEEEEEHHHCCCCCEEEECCCCCCCCEECEEEEEECCCCCCEEEEEE
VADEDSYVSYIEGCSAPVRDSYQLHAAVVEVIIHKNAEVKYSTVQNWFPGDNNTGGILNF
EECCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEHHHCCCCCCCCCCHHHHH
VTKRALCEGENSKMSWTQSETGSAITWKYPSCILRGDNSIGEFYSVALTSGHQQADTGTK
HHHHHHHCCCCCCEEEECCCCCCEEEEECCCEEEECCCCCCHHEEEEECCCCCCCCCCCE
MIHIGKNTKSTIISKGISAGHSQNSYRGLVKIMPTATNARNFTQCDSMLIGANCGAHTFP
EEEECCCCHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCHHHHCCEEEECCCCCCCCC
YVECRNNSAQLEHEATTSRIGEDQLFYCLQRGISEEDAISMIVNGFCKDVFSELPLEFAV
EEEECCCCCCCHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHH
EAQKLLAISLEHSVG
HHHHHHEEEECCCCC
>Mature Secondary Structure 
SRNTEATDDVKTWTGGPLNYKEGFFTQLATDELAKGINEEVVRAISAKRNEPEWMLEFR
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEEEE
LNAYHAWLEMEEPHWLKAHYDKLNYQDYSYYSAPSCGNCDDNCASEPGAVQQTGANAFLS
ECEEEEEEECCCCCHHHHHHHCCCCCCCCEECCCCCCCCCCCCCCCCCCCHHCCCHHHHH
KEVEAAFEQLGVPVREGKEVAVDAIFDSVSVATTYRKKLAEQGIIFCSFGEAIHDHPELV
HHHHHHHHHHCCCHHCCCCEEHHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHCCCHHHH
RKYLGTVVPGNDNFFAALNAAVASDGTFIYVPKGVRCPMELSTYFRINAEKTGQFERTIL
HHHHCEECCCCCCEEEEEEHHHCCCCCEEEECCCCCCCCEECEEEEEECCCCCCEEEEEE
VADEDSYVSYIEGCSAPVRDSYQLHAAVVEVIIHKNAEVKYSTVQNWFPGDNNTGGILNF
EECCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEHHHCCCCCCCCCCHHHHH
VTKRALCEGENSKMSWTQSETGSAITWKYPSCILRGDNSIGEFYSVALTSGHQQADTGTK
HHHHHHHCCCCCCEEEECCCCCCEEEEECCCEEEECCCCCCHHEEEEECCCCCCCCCCCE
MIHIGKNTKSTIISKGISAGHSQNSYRGLVKIMPTATNARNFTQCDSMLIGANCGAHTFP
EEEECCCCHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCHHHHCCEEEECCCCCCCCC
YVECRNNSAQLEHEATTSRIGEDQLFYCLQRGISEEDAISMIVNGFCKDVFSELPLEFAV
EEEECCCCCCCHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHH
EAQKLLAISLEHSVG
HHHHHHEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 10322040 [H]