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The map label for this gene is rz [H]

Identifier: 218689221

GI number: 218689221

Start: 1410866

End: 1411444

Strand: Direct

Name: rz [H]

Synonym: ECED1_1434

Alternate gene names: 218689221

Gene position: 1410866-1411444 (Clockwise)

Preceding gene: 218689220

Following gene: 218689222

Centisome position: 27.08

GC content: 53.37

Gene sequence:

>579_bases
GTGCTGAACTTATTCGGGCAATGGCATTTGCCATTCGTATTGTGGCCATTGCTGTTCTGGTCTGGGCAATTCGTTGGTGG
TGATATGAACCGTGTTCTGTGTGTGGTGATTATTGTCATGCTGGTAGCCTGTGGTGCGCTTAGTCTGGGGCTGAATCATT
ACCGTGATAACGCCATCACCTACAAAGAGCAGCGCGATAAAAAAGTCAGTGAGCTGGAGCAGGCAAATGCAACCATTACT
GATATGCAGCAGCGCCAGCGTGATGTTGCTGCACTTGATGCCAGATACTCGAGGGAATTAGCCGATGCGAGAGCTGAAAA
TGAAACTCTGCGCGCTGACGTTGCCGCTGGTCGTAAGCGCCTGCGGGTCAACGCCACCTGCCCCGGTACCGTGCGTGAAG
CCACCGGCACCTCCGGCGTGGATAATGCAACCGGCCCCCGACTGGCAGACACCGCTGAACGGGATTATTTCATCCTCAGA
GAACGGTTGATGACAATGCAGAAGCAGCTGGAAGGGGCGCAGGACTATATCCGCACTCAGTGCACTAAGCTGGCTTTTTA
TTATCCGGAGGATACATGA

Upstream 100 bases:

>100_bases
TGCTATTAAGTGGGTGGCTGTTGGTATTGCTGTGTCTCCGATGCTGTATGGGCTGGCAAAACTGGTCATTGCGCTGAAAT
CGTGAACTTTAAAAAGATGA

Downstream 100 bases:

>100_bases
AGAAATTACGGGTAACCGTAGAACCTTTTCAGGGAACAATTCCGTTCCGTATTTTGCAGCGTGGTCGTGTTCTTGTTGAA
GGTTCGTTCAGTGGTAAATG

Product: Endopeptidase (Lysis protein) from bacteriophage origin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MLNLFGQWHLPFVLWPLLFWSGQFVGGDMNRVLCVVIIVMLVACGALSLGLNHYRDNAITYKEQRDKKVSELEQANATIT
DMQQRQRDVAALDARYSRELADARAENETLRADVAAGRKRLRVNATCPGTVREATGTSGVDNATGPRLADTAERDYFILR
ERLMTMQKQLEGAQDYIRTQCTKLAFYYPEDT

Sequences:

>Translated_192_residues
MLNLFGQWHLPFVLWPLLFWSGQFVGGDMNRVLCVVIIVMLVACGALSLGLNHYRDNAITYKEQRDKKVSELEQANATIT
DMQQRQRDVAALDARYSRELADARAENETLRADVAAGRKRLRVNATCPGTVREATGTSGVDNATGPRLADTAERDYFILR
ERLMTMQKQLEGAQDYIRTQCTKLAFYYPEDT
>Mature_192_residues
MLNLFGQWHLPFVLWPLLFWSGQFVGGDMNRVLCVVIIVMLVACGALSLGLNHYRDNAITYKEQRDKKVSELEQANATIT
DMQQRQRDVAALDARYSRELADARAENETLRADVAAGRKRLRVNATCPGTVREATGTSGVDNATGPRLADTAERDYFILR
ERLMTMQKQLEGAQDYIRTQCTKLAFYYPEDT

Specific function: Necessary for host cell lysis. It is believed to code for an endopeptidase that cleaves the amino-carboxyl cross-link between the diaminopimelic acid and D-alanine residues in the murein component of the bacterial cell wall [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786769, Length=153, Percent_Identity=66.0130718954248, Blast_Score=197, Evalue=3e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004929 [H]

Pfam domain/function: PF03245 Phage_lysis [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 21753; Mature: 21753

Theoretical pI: Translated: 7.29; Mature: 7.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNLFGQWHLPFVLWPLLFWSGQFVGGDMNRVLCVVIIVMLVACGALSLGLNHYRDNAIT
CCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
YKEQRDKKVSELEQANATITDMQQRQRDVAALDARYSRELADARAENETLRADVAAGRKR
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCHHE
LRVNATCPGTVREATGTSGVDNATGPRLADTAERDYFILRERLMTMQKQLEGAQDYIRTQ
EEECCCCCCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CTKLAFYYPEDT
HHHHEEECCCCC
>Mature Secondary Structure
MLNLFGQWHLPFVLWPLLFWSGQFVGGDMNRVLCVVIIVMLVACGALSLGLNHYRDNAIT
CCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
YKEQRDKKVSELEQANATITDMQQRQRDVAALDARYSRELADARAENETLRADVAAGRKR
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCHHE
LRVNATCPGTVREATGTSGVDNATGPRLADTAERDYFILRERLMTMQKQLEGAQDYIRTQ
EEECCCCCCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CTKLAFYYPEDT
HHHHEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]