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The map label for this gene is yliE [H]

Identifier: 218688616

GI number: 218688616

Start: 830000

End: 832348

Strand: Direct

Name: yliE [H]

Synonym: ECED1_0797

Alternate gene names: 218688616

Gene position: 830000-832348 (Clockwise)

Preceding gene: 218688615

Following gene: 218688617

Centisome position: 15.93

GC content: 41.25

Gene sequence:

>2349_bases
ATGCTGAGTTTATACGAAAAGATAAAGATAAGGCTGATAATTTTATTTTTATTGGCAGCACTGTCATTTATTGGTCTTTT
TTTCATCATTGACTATCAACTGGTATCGGAACGCGCGGTAAAACGTGCCGATAGCCGCTTTGAACTTATTCAGAAAAACG
TTGGCTATTTCTTTAAAGATATTGAACGTTCGGCCCTGACATTAAAGGACTCACTGTATTTATTAAAAAATACAGAGGAG
ATTCAACGTGCCGTGATTCTGAAAATGGAAATGATGCCATTTTTAGACTCGGTGGGACTGGTACTTGATGATAATAAATA
TTATCTCTTTTCGCGGAGGGCGAATGATAAAATCGTTGTTTATCATCAGGAACAAGTAAATGGACCGCTTGTCGACGAGT
CAGGGCGGGTTATTTTTGCCGATTTTAACCCATCGAAACGACCGTGGTCGATGGCTTCAGATGACTCTAACAACAGCTGG
AATCCGGCATACAATTGCTTTGATCGTCCGGGTAAAAAATGTATCTCTTTTACGCTACACATCAACGGCAAAGATCATGA
TTTGTTAGCGGTAGATAAAATTCATGTCGATTTAAACTGGCGATATCTGAACGAGTATCTTGATCACATCAGCGCTAATG
ATGAAGTTCTATTTTTAAAGCAAGGTCATGAGATCATTGCTAAGAATCAACTCGCTCGTGAAAAATTGATTATTTATAAT
AGCGAAGGTAATTATAATATTATTGATTCTGTCGATACGGAATATATTGAAAAAACATCAGCGGTGCCAAACAACGCATT
ATTCGAAATCTATTTTTATTATCCTGGTGGTAATTTATTGAACGCATCAGATAAACTTTTTTATCTGCCGTTTGCTTTCA
TTATTATCGTATTGCTGGTGGTTTATTTAATGACCACTCGAGTGTTCCGTCGGCAATTTTCTGAAATGACAGATTTGGTC
AATACGCTGGCGTTTTTGCCCGACTCTACGGATCAAATCGAGGCTCTGAAGATTCGTGAAGGCGATGCGAAAGAGATTAT
CAGCATCAAAAATTCGATCGCGGAAATGAAAGATGCTGAAATTGAACGGGCAAATAAATTGCTCTCGCTGATCTCTTACG
ATCAGGAAAGCGGTTTTATTAAAAATATGGCGATTATTGAGTCCAACAATAATCAGTATCTGGCTGTGGGGATCATCAAA
CTGTGTGGTCTGGAAGCTGTGGAAGCGGTGTTTGGTTTTGATGAACGCAATAAAATCGTCAGGAAATTGTGTCAGCGAAT
TGCCGAGAAATATGCGCAATGCTGCGATATCGTGACATTTAATGCCGATCTCTATTTACTCCTGTGCCGGGAAAATGTAC
AGACGTTTACCCGTAAGATAGCGACGGTAAACGATTTTGACAGCAGTTTTGGCTACCGCAATCTGCGCATCCATAAGTCT
GCTATTTGTGAACCTTTGCAGGGGGAAAACGCCTGGAGTTACGCAGAAAAGCTGAAACTGGCGATTTCCAGTATCCGCAA
CCATATGTTCTCAGAGTTTATTTTCTGTGATGATGCGAAACTCAACGAAATAGAAGAGAATATCTGGATTGCGCGTAATA
TTCGCCATGCAATGGAAATTGGCGAACTATTCCTGGTCTATCAACCGATTGTTGATATTAACACCCGCACCATTTTGGGC
GCGGAGGCGTTGTGCCGTTGGGTGTCTGCGGAGCGGGGGATTATTTCACCGCTGAAGTTCATTACCATTGCTGAAGATAT
CGGGTTTATCAATGAGCTGGGCTATCAAATTATTAAAACCGCGATGGGTGAATTCAGACATTTTAGCGAGCGTGCGGTCC
TGAAGGACGGTTTCTTACTGCATATTAATGTTTCGCCCTGGCAGTTAAACGAACCACACTTTCATGAGCGTTTTACTACC
ATCATGAAAGAAAATGGCCTGAAGGCGAACAGCCTTTGTGTTGAGATCACTGAAACCGTGATCGAGCGAATTAATGAACA
TTTCTATCTCAATATTGAACAACTGCGTAAACAAGGGGTACGGGTATCGATTGATGACTTTGGCACCGGTTTGTCAAACC
TGAAACGTTTTTATGAAATGAATCCAGACAGTATAAAGGTGGATTCGCAATTTACCGGCGATATTTTCGGTACTGCAGGA
AAAATTGTGCGCATTATTTTCGATCTGGCACGCTATAACCGGATCCCGGTGATTGCGGAAGGCGTAGAGAGCGAAGACGT
TGCGCGTGAATTAATCAAATTAGGATGTGTTCAGGCTCAGGGGTATCTGTACCAGAAACCCATGCCATTCTCCGCCTGGG
ATAAAAGTGGAAAATTAGTAAAAGAGTAG

Upstream 100 bases:

>100_bases
CTGATTTTGTAGAATCGGGTAATTTGGTTAAAAAGCCGCAGCAAGGGACTATTTTGCAGCGGCACAGCGTTCAGACAGTT
ATTTTGTTAAATGTATTAAC

Downstream 100 bases:

>100_bases
TTTACGTATGTCCAGAATCAATAAATTCGTACTTACAGTCAGTCTGCTGATTTTTATCATGATTTCAGCAGTTGCCTGCG
GGATCTACACTCAAATGGTA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 782; Mature: 782

Protein sequence:

>782_residues
MLSLYEKIKIRLIILFLLAALSFIGLFFIIDYQLVSERAVKRADSRFELIQKNVGYFFKDIERSALTLKDSLYLLKNTEE
IQRAVILKMEMMPFLDSVGLVLDDNKYYLFSRRANDKIVVYHQEQVNGPLVDESGRVIFADFNPSKRPWSMASDDSNNSW
NPAYNCFDRPGKKCISFTLHINGKDHDLLAVDKIHVDLNWRYLNEYLDHISANDEVLFLKQGHEIIAKNQLAREKLIIYN
SEGNYNIIDSVDTEYIEKTSAVPNNALFEIYFYYPGGNLLNASDKLFYLPFAFIIIVLLVVYLMTTRVFRRQFSEMTDLV
NTLAFLPDSTDQIEALKIREGDAKEIISIKNSIAEMKDAEIERANKLLSLISYDQESGFIKNMAIIESNNNQYLAVGIIK
LCGLEAVEAVFGFDERNKIVRKLCQRIAEKYAQCCDIVTFNADLYLLLCRENVQTFTRKIATVNDFDSSFGYRNLRIHKS
AICEPLQGENAWSYAEKLKLAISSIRNHMFSEFIFCDDAKLNEIEENIWIARNIRHAMEIGELFLVYQPIVDINTRTILG
AEALCRWVSAERGIISPLKFITIAEDIGFINELGYQIIKTAMGEFRHFSERAVLKDGFLLHINVSPWQLNEPHFHERFTT
IMKENGLKANSLCVEITETVIERINEHFYLNIEQLRKQGVRVSIDDFGTGLSNLKRFYEMNPDSIKVDSQFTGDIFGTAG
KIVRIIFDLARYNRIPVIAEGVESEDVARELIKLGCVQAQGYLYQKPMPFSAWDKSGKLVKE

Sequences:

>Translated_782_residues
MLSLYEKIKIRLIILFLLAALSFIGLFFIIDYQLVSERAVKRADSRFELIQKNVGYFFKDIERSALTLKDSLYLLKNTEE
IQRAVILKMEMMPFLDSVGLVLDDNKYYLFSRRANDKIVVYHQEQVNGPLVDESGRVIFADFNPSKRPWSMASDDSNNSW
NPAYNCFDRPGKKCISFTLHINGKDHDLLAVDKIHVDLNWRYLNEYLDHISANDEVLFLKQGHEIIAKNQLAREKLIIYN
SEGNYNIIDSVDTEYIEKTSAVPNNALFEIYFYYPGGNLLNASDKLFYLPFAFIIIVLLVVYLMTTRVFRRQFSEMTDLV
NTLAFLPDSTDQIEALKIREGDAKEIISIKNSIAEMKDAEIERANKLLSLISYDQESGFIKNMAIIESNNNQYLAVGIIK
LCGLEAVEAVFGFDERNKIVRKLCQRIAEKYAQCCDIVTFNADLYLLLCRENVQTFTRKIATVNDFDSSFGYRNLRIHKS
AICEPLQGENAWSYAEKLKLAISSIRNHMFSEFIFCDDAKLNEIEENIWIARNIRHAMEIGELFLVYQPIVDINTRTILG
AEALCRWVSAERGIISPLKFITIAEDIGFINELGYQIIKTAMGEFRHFSERAVLKDGFLLHINVSPWQLNEPHFHERFTT
IMKENGLKANSLCVEITETVIERINEHFYLNIEQLRKQGVRVSIDDFGTGLSNLKRFYEMNPDSIKVDSQFTGDIFGTAG
KIVRIIFDLARYNRIPVIAEGVESEDVARELIKLGCVQAQGYLYQKPMPFSAWDKSGKLVKE
>Mature_782_residues
MLSLYEKIKIRLIILFLLAALSFIGLFFIIDYQLVSERAVKRADSRFELIQKNVGYFFKDIERSALTLKDSLYLLKNTEE
IQRAVILKMEMMPFLDSVGLVLDDNKYYLFSRRANDKIVVYHQEQVNGPLVDESGRVIFADFNPSKRPWSMASDDSNNSW
NPAYNCFDRPGKKCISFTLHINGKDHDLLAVDKIHVDLNWRYLNEYLDHISANDEVLFLKQGHEIIAKNQLAREKLIIYN
SEGNYNIIDSVDTEYIEKTSAVPNNALFEIYFYYPGGNLLNASDKLFYLPFAFIIIVLLVVYLMTTRVFRRQFSEMTDLV
NTLAFLPDSTDQIEALKIREGDAKEIISIKNSIAEMKDAEIERANKLLSLISYDQESGFIKNMAIIESNNNQYLAVGIIK
LCGLEAVEAVFGFDERNKIVRKLCQRIAEKYAQCCDIVTFNADLYLLLCRENVQTFTRKIATVNDFDSSFGYRNLRIHKS
AICEPLQGENAWSYAEKLKLAISSIRNHMFSEFIFCDDAKLNEIEENIWIARNIRHAMEIGELFLVYQPIVDINTRTILG
AEALCRWVSAERGIISPLKFITIAEDIGFINELGYQIIKTAMGEFRHFSERAVLKDGFLLHINVSPWQLNEPHFHERFTT
IMKENGLKANSLCVEITETVIERINEHFYLNIEQLRKQGVRVSIDDFGTGLSNLKRFYEMNPDSIKVDSQFTGDIFGTAG
KIVRIIFDLARYNRIPVIAEGVESEDVARELIKLGCVQAQGYLYQKPMPFSAWDKSGKLVKE

Specific function: Overexpression reduces biofilm formation. Cyclic-di-GMP is a second messenger which controls cell surface-associated traits in bacteria [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 EAL domain [H]

Homologues:

Organism=Escherichia coli, GI1787055, Length=782, Percent_Identity=98.2097186700767, Blast_Score=1579, Evalue=0.0,
Organism=Escherichia coli, GI1787541, Length=252, Percent_Identity=32.9365079365079, Blast_Score=129, Evalue=6e-31,
Organism=Escherichia coli, GI87081921, Length=272, Percent_Identity=29.4117647058824, Blast_Score=122, Evalue=1e-28,
Organism=Escherichia coli, GI1790496, Length=254, Percent_Identity=31.1023622047244, Blast_Score=115, Evalue=8e-27,
Organism=Escherichia coli, GI87081845, Length=239, Percent_Identity=29.7071129707113, Blast_Score=111, Evalue=2e-25,
Organism=Escherichia coli, GI87082096, Length=294, Percent_Identity=29.2517006802721, Blast_Score=111, Evalue=2e-25,
Organism=Escherichia coli, GI87081980, Length=254, Percent_Identity=30.3149606299213, Blast_Score=101, Evalue=2e-22,
Organism=Escherichia coli, GI1788849, Length=250, Percent_Identity=26.8, Blast_Score=100, Evalue=6e-22,
Organism=Escherichia coli, GI1786507, Length=246, Percent_Identity=29.2682926829268, Blast_Score=99, Evalue=1e-21,
Organism=Escherichia coli, GI226510982, Length=288, Percent_Identity=26.3888888888889, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI1788502, Length=254, Percent_Identity=29.9212598425197, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI87081743, Length=240, Percent_Identity=25.8333333333333, Blast_Score=86, Evalue=9e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001633 [H]

Pfam domain/function: PF00563 EAL [H]

EC number: =3.1.4.52 [H]

Molecular weight: Translated: 90068; Mature: 90068

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: PS50883 EAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSLYEKIKIRLIILFLLAALSFIGLFFIIDYQLVSERAVKRADSRFELIQKNVGYFFKD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IERSALTLKDSLYLLKNTEEIQRAVILKMEMMPFLDSVGLVLDDNKYYLFSRRANDKIVV
HHHHHHHHHHCEEEECCHHHHHHHHHHHHHHHHHHHHCCEEEECCEEEEEEECCCCEEEE
YHQEQVNGPLVDESGRVIFADFNPSKRPWSMASDDSNNSWNPAYNCFDRPGKKCISFTLH
EEHHCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEE
INGKDHDLLAVDKIHVDLNWRYLNEYLDHISANDEVLFLKQGHEIIAKNQLAREKLIIYN
ECCCCCCEEEEEEEEEEEEHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHCCCEEEEEE
SEGNYNIIDSVDTEYIEKTSAVPNNALFEIYFYYPGGNLLNASDKLFYLPFAFIIIVLLV
CCCCEEEECCCCHHHHHHHCCCCCCCEEEEEEEECCCCEECCCCCEEEHHHHHHHHHHHH
VYLMTTRVFRRQFSEMTDLVNTLAFLPDSTDQIEALKIREGDAKEIISIKNSIAEMKDAE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHH
IERANKLLSLISYDQESGFIKNMAIIESNNNQYLAVGIIKLCGLEAVEAVFGFDERNKIV
HHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCEEEEEHHHHHCHHHHHHHHCCCHHHHHH
RKLCQRIAEKYAQCCDIVTFNADLYLLLCRENVQTFTRKIATVNDFDSSFGYRNLRIHKS
HHHHHHHHHHHHHHHCEEEECCCEEEEEEHHHHHHHHHHHHCCCCCCCCCCCCEEEEEHH
AICEPLQGENAWSYAEKLKLAISSIRNHMFSEFIFCDDAKLNEIEENIWIARNIRHAMEI
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHHHHHH
GELFLVYQPIVDINTRTILGAEALCRWVSAERGIISPLKFITIAEDIGFINELGYQIIKT
HHHHEEEECCCCCCCCEEECHHHHHHHHHCCCCCCCCHHHEEEHHHHHHHHHHHHHHHHH
AMGEFRHFSERAVLKDGFLLHINVSPWQLNEPHFHERFTTIMKENGLKANSLCVEITETV
HHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHH
IERINEHFYLNIEQLRKQGVRVSIDDFGTGLSNLKRFYEMNPDSIKVDSQFTGDIFGTAG
HHHCCCCEEEEHHHHHHCCCEEEEHHHCCCHHHHHHHHHCCCCCEEECCCCCCCHHHHHH
KIVRIIFDLARYNRIPVIAEGVESEDVARELIKLGCVQAQGYLYQKPMPFSAWDKSGKLV
HHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCC
KE
CC
>Mature Secondary Structure
MLSLYEKIKIRLIILFLLAALSFIGLFFIIDYQLVSERAVKRADSRFELIQKNVGYFFKD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IERSALTLKDSLYLLKNTEEIQRAVILKMEMMPFLDSVGLVLDDNKYYLFSRRANDKIVV
HHHHHHHHHHCEEEECCHHHHHHHHHHHHHHHHHHHHCCEEEECCEEEEEEECCCCEEEE
YHQEQVNGPLVDESGRVIFADFNPSKRPWSMASDDSNNSWNPAYNCFDRPGKKCISFTLH
EEHHCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEE
INGKDHDLLAVDKIHVDLNWRYLNEYLDHISANDEVLFLKQGHEIIAKNQLAREKLIIYN
ECCCCCCEEEEEEEEEEEEHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHCCCEEEEEE
SEGNYNIIDSVDTEYIEKTSAVPNNALFEIYFYYPGGNLLNASDKLFYLPFAFIIIVLLV
CCCCEEEECCCCHHHHHHHCCCCCCCEEEEEEEECCCCEECCCCCEEEHHHHHHHHHHHH
VYLMTTRVFRRQFSEMTDLVNTLAFLPDSTDQIEALKIREGDAKEIISIKNSIAEMKDAE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHH
IERANKLLSLISYDQESGFIKNMAIIESNNNQYLAVGIIKLCGLEAVEAVFGFDERNKIV
HHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCEEEEEHHHHHCHHHHHHHHCCCHHHHHH
RKLCQRIAEKYAQCCDIVTFNADLYLLLCRENVQTFTRKIATVNDFDSSFGYRNLRIHKS
HHHHHHHHHHHHHHHCEEEECCCEEEEEEHHHHHHHHHHHHCCCCCCCCCCCCEEEEEHH
AICEPLQGENAWSYAEKLKLAISSIRNHMFSEFIFCDDAKLNEIEENIWIARNIRHAMEI
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHHHHHH
GELFLVYQPIVDINTRTILGAEALCRWVSAERGIISPLKFITIAEDIGFINELGYQIIKT
HHHHEEEECCCCCCCCEEECHHHHHHHHHCCCCCCCCHHHEEEHHHHHHHHHHHHHHHHH
AMGEFRHFSERAVLKDGFLLHINVSPWQLNEPHFHERFTTIMKENGLKANSLCVEITETV
HHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHH
IERINEHFYLNIEQLRKQGVRVSIDDFGTGLSNLKRFYEMNPDSIKVDSQFTGDIFGTAG
HHHCCCCEEEEHHHHHHCCCEEEEHHHCCCHHHHHHHHHCCCCCEEECCCCCCCHHHHHH
KIVRIIFDLARYNRIPVIAEGVESEDVARELIKLGCVQAQGYLYQKPMPFSAWDKSGKLV
HHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCC
KE
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]