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The map label for this gene is modB [H]

Identifier: 218688549

GI number: 218688549

Start: 754858

End: 755547

Strand: Direct

Name: modB [H]

Synonym: ECED1_0726

Alternate gene names: 218688549

Gene position: 754858-755547 (Clockwise)

Preceding gene: 218688548

Following gene: 218688550

Centisome position: 14.49

GC content: 53.62

Gene sequence:

>690_bases
ATGATACTGACCGATCCAGAATGGCAGGCAGTTTTATTAAGCCTGAAAGTTTCTTCCCTGGCTGTGCTGTTTAGCCTGCC
GTTTGGGATCTTTTTTGCCTGGTTACTGGTACGTTGCACGTTTCCGGGCAAAGCTCTGCTCGACAGCGTACTGCATCTAC
CGCTGGTGTTACCGCCCGTGGTCGTCGGTTACCTATTATTAGTTTCGATGGGACGGCGCGGATTTATCGGTGAACGTCTG
TATGACTGGTTTGGTCTTTCTTTCGCGTTTAGCTGGCGTGGTGCGGTTCTCGCTGCCGCTGTCATGTCTTTTCCGCTGAT
GGTGCGGGCGATTCGTCTGGCGCTGGAAGGTGTTGATATCAAACTGGAGCAGGCCGCAAGAACACTGGGGGCCGGGCGCT
GGCGCGTTTTCTTTACTATCACGTTACCGCTGACCTTACCGGGAATTATTGTTGGTACGGTGCTGGCATTCGCTCGTTCG
CTCGGTGAATTTGGCGCAACCATCACCTTTGTTTCTAACATTCCTGGTGAAACGCGAACCATTCCTTCTGCCATGTATAC
CCTGATCCAGACCCCTGGCGGGGAAAGTGGCGCGGCGAGACTGTGTATTATTTCTATTGCGCTGGCGATGATCTCCCTGT
TGATTTCAGAATGGCTGGCCAGAATCAGCCGTGAGCGGGCGGGGCGCTAA

Upstream 100 bases:

>100_bases
TGGAAGGGCATAACAATGCGACAGTGAAAGCATTTTACGATTATCTGAAGGGGCCGCAGGCTGCGGAAATCTTTAAACGT
TACGGATTTACAACCAAGTA

Downstream 100 bases:

>100_bases
TCATGCTGGAACTGAATTTTTCCCAGACGTTGGGCAATCATTGCCTGACGATTAATGAAACGCTGCCCGCCAATGGCATC
ACCGCTATTTTTGGTGTCTC

Product: molybdate ABC transporter permease

Products: ADP; phosphate; MoO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MILTDPEWQAVLLSLKVSSLAVLFSLPFGIFFAWLLVRCTFPGKALLDSVLHLPLVLPPVVVGYLLLVSMGRRGFIGERL
YDWFGLSFAFSWRGAVLAAAVMSFPLMVRAIRLALEGVDIKLEQAARTLGAGRWRVFFTITLPLTLPGIIVGTVLAFARS
LGEFGATITFVSNIPGETRTIPSAMYTLIQTPGGESGAARLCIISIALAMISLLISEWLARISRERAGR

Sequences:

>Translated_229_residues
MILTDPEWQAVLLSLKVSSLAVLFSLPFGIFFAWLLVRCTFPGKALLDSVLHLPLVLPPVVVGYLLLVSMGRRGFIGERL
YDWFGLSFAFSWRGAVLAAAVMSFPLMVRAIRLALEGVDIKLEQAARTLGAGRWRVFFTITLPLTLPGIIVGTVLAFARS
LGEFGATITFVSNIPGETRTIPSAMYTLIQTPGGESGAARLCIISIALAMISLLISEWLARISRERAGR
>Mature_229_residues
MILTDPEWQAVLLSLKVSSLAVLFSLPFGIFFAWLLVRCTFPGKALLDSVLHLPLVLPPVVVGYLLLVSMGRRGFIGERL
YDWFGLSFAFSWRGAVLAAAVMSFPLMVRAIRLALEGVDIKLEQAARTLGAGRWRVFFTITLPLTLPGIIVGTVLAFARS
LGEFGATITFVSNIPGETRTIPSAMYTLIQTPGGESGAARLCIISIALAMISLLISEWLARISRERAGR

Specific function: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4149

COG function: function code P; ABC-type molybdate transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1786980, Length=229, Percent_Identity=98.6899563318777, Blast_Score=442, Evalue=1e-125,
Organism=Escherichia coli, GI1788764, Length=232, Percent_Identity=34.051724137931, Blast_Score=124, Evalue=4e-30,
Organism=Escherichia coli, GI87082099, Length=232, Percent_Identity=34.9137931034483, Blast_Score=110, Evalue=9e-26,
Organism=Escherichia coli, GI1787369, Length=185, Percent_Identity=30.2702702702703, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515
- InterPro:   IPR011867 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 24939; Mature: 24939

Theoretical pI: Translated: 10.71; Mature: 10.71

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILTDPEWQAVLLSLKVSSLAVLFSLPFGIFFAWLLVRCTFPGKALLDSVLHLPLVLPPV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
VVGYLLLVSMGRRGFIGERLYDWFGLSFAFSWRGAVLAAAVMSFPLMVRAIRLALEGVDI
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
KLEQAARTLGAGRWRVFFTITLPLTLPGIIVGTVLAFARSLGEFGATITFVSNIPGETRT
HHHHHHHHHCCCCEEEEEEEEECHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCHH
IPSAMYTLIQTPGGESGAARLCIISIALAMISLLISEWLARISRERAGR
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MILTDPEWQAVLLSLKVSSLAVLFSLPFGIFFAWLLVRCTFPGKALLDSVLHLPLVLPPV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
VVGYLLLVSMGRRGFIGERLYDWFGLSFAFSWRGAVLAAAVMSFPLMVRAIRLALEGVDI
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
KLEQAARTLGAGRWRVFFTITLPLTLPGIIVGTVLAFARSLGEFGATITFVSNIPGETRT
HHHHHHHHHCCCCEEEEEEEEECHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCHH
IPSAMYTLIQTPGGESGAARLCIISIALAMISLLISEWLARISRERAGR
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; MoO42- [Periplasm]; H2O [C]

Specific reaction: ATP + MoO42- [Periplasm] + H2O = ADP + phosphate + MoO42- [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]