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The map label for this gene is nadA [H]

Identifier: 218688534

GI number: 218688534

Start: 741076

End: 742119

Strand: Direct

Name: nadA [H]

Synonym: ECED1_0711

Alternate gene names: 218688534

Gene position: 741076-742119 (Clockwise)

Preceding gene: 218688533

Following gene: 218688535

Centisome position: 14.23

GC content: 50.57

Gene sequence:

>1044_bases
ATGAGCGTGATGTTTGATCCAGACACGGCGATTTATCCTTTCCCCCCGAAGCCGACGCCGTTAAGCATTGATGAAAAAGC
GTATTACCGCGAGAAGATAAAACGTCTACTAAAAGAACGTAATGCGGTGATGGTTGCCCACTACTATACCGATCCCGAAA
TTCAACAACTGGCAGAAGAAACCGGTGGCTGTATTTCTGATTCTCTGGAAATGGCGCGCTTCGGTGCAAAGCATCCCGCT
TCTACGTTGTTAGTTGCTGGGGTGAGATTTATGGGAGAAACCGCCAAAATTCTCAGTCCGGAAAAAACAATTCTGATGCC
GACACTTCAGGCTGAATGTTCACTGGATCTCGGCTGCCCTGTTGAAGAATTTAACGCATTTTGCGATGCCCATCCCGATC
GTACTGTCGTCGTCTACGCCAACACTTCTGCTGCGGTAAAAGCGCGCGCAGATTGGGTGGTAACTTCAAGCATTGCCGTC
GAACTTATTGATCATCTGGATAGTTTAGGTGAAAAAATCATCTGGGCACCTGACAAACATCTGGGGTGTTACGTGCAAAA
ACAGACGGGCGCAGACATTTTATGCTGGCAGGGTGCCTGCATTGTGCATGATGAGTTTAAGACTCAGGCGTTAACCCGCT
TGCAAGAAGAATACCCGGATGCTGCCATACTGGTGCATCCAGAATCACCGCAAGCTATTGTAGAGATGGCGGATGCGGTC
GGTTCCACCAGTCAACTGATCGCTGCTGCGAAAACATTGCCACATCAGCGGCTTATCGTGGCAACCGATCGGGGCATTTT
CTACAAAATGCAGCAGGCGGTGCCAGATAAAGAGTTACTGGAAGCACCAACCGCGGGTGAGGGCGCAACCTGTCGCAGCT
GCGCGCATTGCCCGTGGATGGCCATGAATGGCCTTCAGGCCATCGCAGAGGCATTAGAACTGGAAGGAAGCAATCACGAG
GTTTATGTTGATGAAAGGCTGCTAGAGAGGGCGCTGGTGCCGCTCAATCGTATGCTGGATTTTGCGGCTACACTACGTGG
ATAA

Upstream 100 bases:

>100_bases
TCGACTATCTTGTTTAGCATATAAAACAAATTACGCCGATAATAGCGAATATCACGCTTAAGTCGGTTTTAACGTTAAGC
CTGTAAAACGAGATGGTAAG

Downstream 100 bases:

>100_bases
TTGATAATAAGGCGTCACATTACGCTTTGGGGGAACGATGGATTTTTTTAGTGTGCAGAATATCCTGGTACATATACCAA
TAGGGGCAGGCGGTTATGAT

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 346

Protein sequence:

>347_residues
MSVMFDPDTAIYPFPPKPTPLSIDEKAYYREKIKRLLKERNAVMVAHYYTDPEIQQLAEETGGCISDSLEMARFGAKHPA
STLLVAGVRFMGETAKILSPEKTILMPTLQAECSLDLGCPVEEFNAFCDAHPDRTVVVYANTSAAVKARADWVVTSSIAV
ELIDHLDSLGEKIIWAPDKHLGCYVQKQTGADILCWQGACIVHDEFKTQALTRLQEEYPDAAILVHPESPQAIVEMADAV
GSTSQLIAAAKTLPHQRLIVATDRGIFYKMQQAVPDKELLEAPTAGEGATCRSCAHCPWMAMNGLQAIAEALELEGSNHE
VYVDERLLERALVPLNRMLDFAATLRG

Sequences:

>Translated_347_residues
MSVMFDPDTAIYPFPPKPTPLSIDEKAYYREKIKRLLKERNAVMVAHYYTDPEIQQLAEETGGCISDSLEMARFGAKHPA
STLLVAGVRFMGETAKILSPEKTILMPTLQAECSLDLGCPVEEFNAFCDAHPDRTVVVYANTSAAVKARADWVVTSSIAV
ELIDHLDSLGEKIIWAPDKHLGCYVQKQTGADILCWQGACIVHDEFKTQALTRLQEEYPDAAILVHPESPQAIVEMADAV
GSTSQLIAAAKTLPHQRLIVATDRGIFYKMQQAVPDKELLEAPTAGEGATCRSCAHCPWMAMNGLQAIAEALELEGSNHE
VYVDERLLERALVPLNRMLDFAATLRG
>Mature_346_residues
SVMFDPDTAIYPFPPKPTPLSIDEKAYYREKIKRLLKERNAVMVAHYYTDPEIQQLAEETGGCISDSLEMARFGAKHPAS
TLLVAGVRFMGETAKILSPEKTILMPTLQAECSLDLGCPVEEFNAFCDAHPDRTVVVYANTSAAVKARADWVVTSSIAVE
LIDHLDSLGEKIIWAPDKHLGCYVQKQTGADILCWQGACIVHDEFKTQALTRLQEEYPDAAILVHPESPQAIVEMADAVG
STSQLIAAAKTLPHQRLIVATDRGIFYKMQQAVPDKELLEAPTAGEGATCRSCAHCPWMAMNGLQAIAEALELEGSNHEV
YVDERLLERALVPLNRMLDFAATLRG

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=347, Percent_Identity=98.2708933717579, Blast_Score=705, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 38184; Mature: 38053

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVMFDPDTAIYPFPPKPTPLSIDEKAYYREKIKRLLKERNAVMVAHYYTDPEIQQLAEE
CCEEECCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEEEECCCHHHHHHHHH
TGGCISDSLEMARFGAKHPASTLLVAGVRFMGETAKILSPEKTILMPTLQAECSLDLGCP
HCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHCCCCCEEEEEECCCCCCCCCCCC
VEEFNAFCDAHPDRTVVVYANTSAAVKARADWVVTSSIAVELIDHLDSLGEKIIWAPDKH
HHHHHHHHCCCCCCEEEEEECCCCEEEECCCEEEHHHHHHHHHHHHHHHCCEEEECCCCC
LGCYVQKQTGADILCWQGACIVHDEFKTQALTRLQEEYPDAAILVHPESPQAIVEMADAV
CCEEEEECCCCEEEEECCEEEEEHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHH
GSTSQLIAAAKTLPHQRLIVATDRGIFYKMQQAVPDKELLEAPTAGEGATCRSCAHCPWM
CCHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHCCCHHHHCCCCCCCCCCCHHHCCCCHH
AMNGLQAIAEALELEGSNHEVYVDERLLERALVPLNRMLDFAATLRG
HHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SVMFDPDTAIYPFPPKPTPLSIDEKAYYREKIKRLLKERNAVMVAHYYTDPEIQQLAEE
CEEECCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEEEECCCHHHHHHHHH
TGGCISDSLEMARFGAKHPASTLLVAGVRFMGETAKILSPEKTILMPTLQAECSLDLGCP
HCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHCCCCCEEEEEECCCCCCCCCCCC
VEEFNAFCDAHPDRTVVVYANTSAAVKARADWVVTSSIAVELIDHLDSLGEKIIWAPDKH
HHHHHHHHCCCCCCEEEEEECCCCEEEECCCEEEHHHHHHHHHHHHHHHCCEEEECCCCC
LGCYVQKQTGADILCWQGACIVHDEFKTQALTRLQEEYPDAAILVHPESPQAIVEMADAV
CCEEEEECCCCEEEEECCEEEEEHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHH
GSTSQLIAAAKTLPHQRLIVATDRGIFYKMQQAVPDKELLEAPTAGEGATCRSCAHCPWM
CCHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHCCCHHHHCCCCCCCCCCCHHHCCCCHH
AMNGLQAIAEALELEGSNHEVYVDERLLERALVPLNRMLDFAATLRG
HHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA