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The map label for this gene is yajO [H]

Identifier: 218688282

GI number: 218688282

Start: 458008

End: 458982

Strand: Reverse

Name: yajO [H]

Synonym: ECED1_0442

Alternate gene names: 218688282

Gene position: 458982-458008 (Counterclockwise)

Preceding gene: 218688283

Following gene: 218688275

Centisome position: 8.81

GC content: 53.64

Gene sequence:

>975_bases
ATGCAATACAACCCCTTAGGAAAAACCGACCTTCGTGTTTCCCGACTTTGCCTCGGCTGTATGACCTTTGGCGAGCCAGA
TCGCGGTAATCACGCATGGACACTGCCGGAAGAGAGCAGCCGTCCCATCATTAAACGCGCACTGGAAGGCGGCATAAATT
TCTTTGATACCGCCAATAGCTATTCCGATGGCAGCAGCGAAGAGATCGTCGGTCGCGCACTGCGGGATTTCGCCCGTCGT
GAAGACGTGGTCGTTGCGACCAAAGTGTTCCATCGCGTTGGTGATTTACCGGAAGGATTATCCCGTGCACAAATTTTGCG
CTCTATCGACGACAGCCTGCTCCGTCTCGGCATGGATTATGTCGATATCCTGCAAATTCATCGCTGGGATTACAACACGC
CGATCGAAGAGACGCTGGAAGCCCTGAACGACGTGGTAAAAGCCGGGAAAGCGCGTTATATCGGCGCGTCATCCATGCAC
GCTTCGCAGTTTGCTCAGGCACTGGAACTACAAAAACAGCACGGCTGGGCGCAGTTTGTCAGTATGCAGGATCACTACAA
TCTGATTTATCGTGAAGAAGAGCGCGAGATGCTGCCGCTGTGTTATCAGGAAGGCGTGGCGGTGATTCCATGGAGTCCGC
TGGCGCGGGGCCGTCTGACGCGTCCTTGGGGAGAAACCACCGCACGGCTGGTGTCGGATGAAGTGGGGAAAAATCTCTAC
CAAGAAAGCAATGAAAATGACGCACAAATTGCAGAACGCTTAACGGGCGTCAGTGAAGAACTTGGTGCAACGCGAGCACA
AGTTGCGCTGGCCTGGTTGTTGAGTAAACCGGGCATTGCCGCACCGATTATCGGAACTTCTCGGGAGGAACAGCTTGATG
AACTGCTAAACGCGGTGGATATCACCTTGAAGCCGGAACAGATCGCCGAGCTGGAAACGCCGTATAAACCGCATCCGGTC
GTAGGATTTAAATAG

Upstream 100 bases:

>100_bases
CGATGCCACCGGTATGGAAGCCAAAATCAAAGCCTGGCTGGCATAATCCCTACTCTACTCCTGCTATGCTTAAGAAATTA
TTCATGGCAGGAGTGGCAGC

Downstream 100 bases:

>100_bases
GTATGCAGGCCTGATGAGACGTGACAAGCGTCACATCAGGCATCGGTGCACAACTACGACAGAATACCCAGCGGCCAGTG
ATGACCGATAAAATACAGGA

Product: aldoketo-oxidoreductase, NADP-binding

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MQYNPLGKTDLRVSRLCLGCMTFGEPDRGNHAWTLPEESSRPIIKRALEGGINFFDTANSYSDGSSEEIVGRALRDFARR
EDVVVATKVFHRVGDLPEGLSRAQILRSIDDSLLRLGMDYVDILQIHRWDYNTPIEETLEALNDVVKAGKARYIGASSMH
ASQFAQALELQKQHGWAQFVSMQDHYNLIYREEEREMLPLCYQEGVAVIPWSPLARGRLTRPWGETTARLVSDEVGKNLY
QESNENDAQIAERLTGVSEELGATRAQVALAWLLSKPGIAAPIIGTSREEQLDELLNAVDITLKPEQIAELETPYKPHPV
VGFK

Sequences:

>Translated_324_residues
MQYNPLGKTDLRVSRLCLGCMTFGEPDRGNHAWTLPEESSRPIIKRALEGGINFFDTANSYSDGSSEEIVGRALRDFARR
EDVVVATKVFHRVGDLPEGLSRAQILRSIDDSLLRLGMDYVDILQIHRWDYNTPIEETLEALNDVVKAGKARYIGASSMH
ASQFAQALELQKQHGWAQFVSMQDHYNLIYREEEREMLPLCYQEGVAVIPWSPLARGRLTRPWGETTARLVSDEVGKNLY
QESNENDAQIAERLTGVSEELGATRAQVALAWLLSKPGIAAPIIGTSREEQLDELLNAVDITLKPEQIAELETPYKPHPV
VGFK
>Mature_324_residues
MQYNPLGKTDLRVSRLCLGCMTFGEPDRGNHAWTLPEESSRPIIKRALEGGINFFDTANSYSDGSSEEIVGRALRDFARR
EDVVVATKVFHRVGDLPEGLSRAQILRSIDDSLLRLGMDYVDILQIHRWDYNTPIEETLEALNDVVKAGKARYIGASSMH
ASQFAQALELQKQHGWAQFVSMQDHYNLIYREEEREMLPLCYQEGVAVIPWSPLARGRLTRPWGETTARLVSDEVGKNLY
QESNENDAQIAERLTGVSEELGATRAQVALAWLLSKPGIAAPIIGTSREEQLDELLNAVDITLKPEQIAELETPYKPHPV
VGFK

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436964, Length=313, Percent_Identity=33.2268370607029, Blast_Score=153, Evalue=2e-37,
Organism=Homo sapiens, GI27436962, Length=316, Percent_Identity=33.2278481012658, Blast_Score=152, Evalue=3e-37,
Organism=Homo sapiens, GI27436971, Length=333, Percent_Identity=32.4324324324324, Blast_Score=151, Evalue=1e-36,
Organism=Homo sapiens, GI27436969, Length=315, Percent_Identity=32.3809523809524, Blast_Score=150, Evalue=1e-36,
Organism=Homo sapiens, GI27436966, Length=313, Percent_Identity=32.9073482428115, Blast_Score=149, Evalue=3e-36,
Organism=Homo sapiens, GI4504825, Length=313, Percent_Identity=32.2683706070287, Blast_Score=149, Evalue=3e-36,
Organism=Homo sapiens, GI223718702, Length=280, Percent_Identity=27.8571428571429, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI41152114, Length=283, Percent_Identity=27.5618374558304, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI41327764, Length=273, Percent_Identity=28.2051282051282, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI223718708, Length=139, Percent_Identity=33.8129496402878, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI87081735, Length=324, Percent_Identity=99.0740740740741, Blast_Score=663, Evalue=0.0,
Organism=Escherichia coli, GI1789375, Length=330, Percent_Identity=35.7575757575758, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI1788070, Length=324, Percent_Identity=33.9506172839506, Blast_Score=137, Evalue=7e-34,
Organism=Escherichia coli, GI1789199, Length=348, Percent_Identity=28.1609195402299, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1788081, Length=301, Percent_Identity=28.2392026578073, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1787674, Length=316, Percent_Identity=27.8481012658228, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI48994888, Length=289, Percent_Identity=24.9134948096886, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI212645785, Length=313, Percent_Identity=27.7955271565495, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17566692, Length=304, Percent_Identity=23.0263157894737, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6325169, Length=334, Percent_Identity=38.9221556886228, Blast_Score=241, Evalue=2e-64,
Organism=Saccharomyces cerevisiae, GI6323998, Length=327, Percent_Identity=31.4984709480122, Blast_Score=140, Evalue=3e-34,
Organism=Saccharomyces cerevisiae, GI6319958, Length=295, Percent_Identity=30.1694915254237, Blast_Score=132, Evalue=6e-32,
Organism=Saccharomyces cerevisiae, GI6319951, Length=315, Percent_Identity=28.2539682539683, Blast_Score=124, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6322615, Length=246, Percent_Identity=30.8943089430894, Blast_Score=115, Evalue=8e-27,
Organism=Saccharomyces cerevisiae, GI6321052, Length=155, Percent_Identity=31.6129032258064, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24640980, Length=345, Percent_Identity=27.2463768115942, Blast_Score=115, Evalue=5e-26,
Organism=Drosophila melanogaster, GI45549126, Length=345, Percent_Identity=27.2463768115942, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24646155, Length=318, Percent_Identity=30.8176100628931, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24646159, Length=311, Percent_Identity=30.2250803858521, Blast_Score=91, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 36377; Mature: 36377

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQYNPLGKTDLRVSRLCLGCMTFGEPDRGNHAWTLPEESSRPIIKRALEGGINFFDTANS
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCC
YSDGSSEEIVGRALRDFARREDVVVATKVFHRVGDLPEGLSRAQILRSIDDSLLRLGMDY
CCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHH
VDILQIHRWDYNTPIEETLEALNDVVKAGKARYIGASSMHASQFAQALELQKQHGWAQFV
HHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHHCCHHHHH
SMQDHYNLIYREEEREMLPLCYQEGVAVIPWSPLARGRLTRPWGETTARLVSDEVGKNLY
HHHHHHHHEEECCHHHHHHHHHHCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
QESNENDAQIAERLTGVSEELGATRAQVALAWLLSKPGIAAPIIGTSREEQLDELLNAVD
HCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHC
ITLKPEQIAELETPYKPHPVVGFK
CCCCHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MQYNPLGKTDLRVSRLCLGCMTFGEPDRGNHAWTLPEESSRPIIKRALEGGINFFDTANS
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCC
YSDGSSEEIVGRALRDFARREDVVVATKVFHRVGDLPEGLSRAQILRSIDDSLLRLGMDY
CCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHH
VDILQIHRWDYNTPIEETLEALNDVVKAGKARYIGASSMHASQFAQALELQKQHGWAQFV
HHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHHCCHHHHH
SMQDHYNLIYREEEREMLPLCYQEGVAVIPWSPLARGRLTRPWGETTARLVSDEVGKNLY
HHHHHHHHEEECCHHHHHHHHHHCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
QESNENDAQIAERLTGVSEELGATRAQVALAWLLSKPGIAAPIIGTSREEQLDELLNAVD
HCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHC
ITLKPEQIAELETPYKPHPVVGFK
CCCCHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]