| Definition | Escherichia coli ED1a chromosome, complete genome. |
|---|---|
| Accession | NC_011745 |
| Length | 5,209,548 |
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The map label for this gene is iolC [H]
Identifier: 218688159
GI number: 218688159
Start: 328589
End: 330526
Strand: Reverse
Name: iolC [H]
Synonym: ECED1_0311
Alternate gene names: 218688159
Gene position: 330526-328589 (Counterclockwise)
Preceding gene: 218688163
Following gene: 218688158
Centisome position: 6.34
GC content: 56.09
Gene sequence:
>1938_bases ATGTCAATGAATAAAGCAGTCAGTAGTGAGCAAAAGCCGCTGGACGTTATCTGTCTGGGACGAGTCGCTGTTGATTTGTA TGGTCAACAAATCGGGTCGCGGCTGGAGGATATGACGACTTTCGCTAAATATTTAGGGGGATCGTCAGGCAATGTTGCCT ACGGCACGGCCATTCAGGGATTACGTTCCGCTATGCTGGCCCGCGTCGGCGATGAGCATATGGGACGTTTCGTTCGTGAA GAATTAAACCGCGTTGGTGTGGATACGCAGTGCCTGCTGTCGGATCGCGATCGTCTGACCGCGCTGGTGATCCTCGGCAT TAAAGATCAGGACACCTTTCCTCTGATCTTCTACCGCGATAACTGCGCGGACATGGCGCTAACACCCGAGGATATCCGCG AAGATTACATCGCTTCTTCACGCGCATTAGCCGTCACTGGTACCCATCTTTCTCACCCCAATACGCGCGCCGCCGTTCTT AAAGCACTGGAGTATGCGCAAAAACACGGGCTGCGGCGGGTGCTGGATATCGACTACCGCCCCGTACTGTGGGGCCTGAC GTCGCTAGGAGACGGTGAAACGCGTTTCATCGCCTCATCACAGGTTACCGAACAGCTCCAGCAGGTATTGCGCCATTTCG ATCTGATCGTTGGGACCGAAGAAGAATTCCATATCGCCGGCGGCAGTACCGACACGCTGACCGCCCTGCGGCGCGTCCGT CAGTTGACCCAAGCCGTACTGGTGTGCAAACGCGGCGCGCTGGGCTGCTCAGTCTTTGAAGGCAACATTGCCGATGACTG GTCGCAGGTGAAGATACATAGCGGCGTTCGCGTAGACGTTCTGAACGTTCTGGGCGCGGGCGATGCCTTTATGTCAGGAC TGCTGCGGGGATACCTGAACGATGAAAGCTGGGAGCAAGCCTGCCGTTATGCAAACGCCTGCGGCGCGTTAGTGGTATCG CGCCACGGTTGTGCCCCCGCCATGCCAACCAAAAAAGAGCTGGACGACTACCTCGCGCGTGAACAATCCATCACCCGGCC AGACAAAGACCCGCGGCTGAATCACCTTCATCGGGTCACAACCCGTAAACAGCACTGGCCGGAGCTGTGCGTATTCGCCT TCGACCATCGCAAGCAACTGGTGGATATCGCAAATGAAGTCGGCGCCAGTGAATCCGCGATCCCCCCTCTGAAGATGCTA CTGCTGGAAGGGGCGCGTCAGGCGGCGCTTGAGGCCGGTTTACAGAATAATAGCGGCATCCTTGCCGATACCACCTTTGG TCAGCAGGCGCTTAACGACGTGACCGGCCAGGGATGGTGGATTGGCCGACCGGTTGAGATGCCCGGTTCGTATCCGCTGA AGCTGGAACATGGCGATATTGGCTCTCAGCTTGTCAGCTGGCCGCAAGAGCACGTCGTGAAATGTCTGGTCTTCTATCAT CCACTCGATGCAGAGTCGGTACGTCTTGAACAAGAGGCGCTCATTGACGAGGTTTACCGCGCCTGCTGCCAGTCTGGTCA CGATCTGCTGCTGGAAGTCATCTTGCCGCGCGATACGGCAGACCAAAATGAGCAATACTATCCTCAGATTGTGGAACGTT TTTATCAACTGGGGATCCTGCCGGACTGGTGGAAACTGCCACCGTTAAGCCCAGATCGTTGGCGAGAAATCAGCCAGCAT ATTGAGCATTATGACCCTGAATGTCGCGGTATATTGATACTTGGCCTGGACGCACCGGAAAGCGAGTTGAAGTCAGGATT CGCCGCAGCAGCGGATATGCCCTGGGTGAAAGGTTTCGCCGTCGGCCGGACCATCTTTGGCGAACCGTCACGCCAGTGGT TAGGCGGCCAGCTTAACGATGAACAGCTCATCGCAACGGTGAAACAAAAATACCGCATGCTTATTGACTACTGGCGCGAA TACCGCCCGGCACGTTAA
Upstream 100 bases:
>100_bases TTATTCAAACAATAAATGAAAACGTCATTCCATTTTTATTGAAAATGAAATCACCAAACCTTAGTATAAGCAAAAATAAC ACCGTCTTCTGTTAGGGGAT
Downstream 100 bases:
>100_bases TGCCTGCCTCATCACGCCCCGTGTCTGCATCGGACAAGGGGCGTGTTCGAGTAGGCAGCCTGGCGGCTGCGGCTTGTCAT GACCTGATATTACCGTTATA
Product: putative carbohydrate kinase
Products: NA
Alternate protein names: 2-deoxy-5-keto-D-gluconate kinase; DKG kinase [H]
Number of amino acids: Translated: 645; Mature: 644
Protein sequence:
>645_residues MSMNKAVSSEQKPLDVICLGRVAVDLYGQQIGSRLEDMTTFAKYLGGSSGNVAYGTAIQGLRSAMLARVGDEHMGRFVRE ELNRVGVDTQCLLSDRDRLTALVILGIKDQDTFPLIFYRDNCADMALTPEDIREDYIASSRALAVTGTHLSHPNTRAAVL KALEYAQKHGLRRVLDIDYRPVLWGLTSLGDGETRFIASSQVTEQLQQVLRHFDLIVGTEEEFHIAGGSTDTLTALRRVR QLTQAVLVCKRGALGCSVFEGNIADDWSQVKIHSGVRVDVLNVLGAGDAFMSGLLRGYLNDESWEQACRYANACGALVVS RHGCAPAMPTKKELDDYLAREQSITRPDKDPRLNHLHRVTTRKQHWPELCVFAFDHRKQLVDIANEVGASESAIPPLKML LLEGARQAALEAGLQNNSGILADTTFGQQALNDVTGQGWWIGRPVEMPGSYPLKLEHGDIGSQLVSWPQEHVVKCLVFYH PLDAESVRLEQEALIDEVYRACCQSGHDLLLEVILPRDTADQNEQYYPQIVERFYQLGILPDWWKLPPLSPDRWREISQH IEHYDPECRGILILGLDAPESELKSGFAAAADMPWVKGFAVGRTIFGEPSRQWLGGQLNDEQLIATVKQKYRMLIDYWRE YRPAR
Sequences:
>Translated_645_residues MSMNKAVSSEQKPLDVICLGRVAVDLYGQQIGSRLEDMTTFAKYLGGSSGNVAYGTAIQGLRSAMLARVGDEHMGRFVRE ELNRVGVDTQCLLSDRDRLTALVILGIKDQDTFPLIFYRDNCADMALTPEDIREDYIASSRALAVTGTHLSHPNTRAAVL KALEYAQKHGLRRVLDIDYRPVLWGLTSLGDGETRFIASSQVTEQLQQVLRHFDLIVGTEEEFHIAGGSTDTLTALRRVR QLTQAVLVCKRGALGCSVFEGNIADDWSQVKIHSGVRVDVLNVLGAGDAFMSGLLRGYLNDESWEQACRYANACGALVVS RHGCAPAMPTKKELDDYLAREQSITRPDKDPRLNHLHRVTTRKQHWPELCVFAFDHRKQLVDIANEVGASESAIPPLKML LLEGARQAALEAGLQNNSGILADTTFGQQALNDVTGQGWWIGRPVEMPGSYPLKLEHGDIGSQLVSWPQEHVVKCLVFYH PLDAESVRLEQEALIDEVYRACCQSGHDLLLEVILPRDTADQNEQYYPQIVERFYQLGILPDWWKLPPLSPDRWREISQH IEHYDPECRGILILGLDAPESELKSGFAAAADMPWVKGFAVGRTIFGEPSRQWLGGQLNDEQLIATVKQKYRMLIDYWRE YRPAR >Mature_644_residues SMNKAVSSEQKPLDVICLGRVAVDLYGQQIGSRLEDMTTFAKYLGGSSGNVAYGTAIQGLRSAMLARVGDEHMGRFVREE LNRVGVDTQCLLSDRDRLTALVILGIKDQDTFPLIFYRDNCADMALTPEDIREDYIASSRALAVTGTHLSHPNTRAAVLK ALEYAQKHGLRRVLDIDYRPVLWGLTSLGDGETRFIASSQVTEQLQQVLRHFDLIVGTEEEFHIAGGSTDTLTALRRVRQ LTQAVLVCKRGALGCSVFEGNIADDWSQVKIHSGVRVDVLNVLGAGDAFMSGLLRGYLNDESWEQACRYANACGALVVSR HGCAPAMPTKKELDDYLAREQSITRPDKDPRLNHLHRVTTRKQHWPELCVFAFDHRKQLVDIANEVGASESAIPPLKMLL LEGARQAALEAGLQNNSGILADTTFGQQALNDVTGQGWWIGRPVEMPGSYPLKLEHGDIGSQLVSWPQEHVVKCLVFYHP LDAESVRLEQEALIDEVYRACCQSGHDLLLEVILPRDTADQNEQYYPQIVERFYQLGILPDWWKLPPLSPDRWREISQHI EHYDPECRGILILGLDAPESELKSGFAAAADMPWVKGFAVGRTIFGEPSRQWLGGQLNDEQLIATVKQKYRMLIDYWREY RPAR
Specific function: Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP) [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the carbohydrate kinase pfkB family [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011611 - InterPro: IPR002173 - InterPro: IPR022841 [H]
Pfam domain/function: PF00294 PfkB [H]
EC number: =2.7.1.92 [H]
Molecular weight: Translated: 72219; Mature: 72088
Theoretical pI: Translated: 5.72; Mature: 5.72
Prosite motif: PS00584 PFKB_KINASES_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
2.0 %Cys (Translated Protein) 1.9 %Met (Translated Protein) 3.9 %Cys+Met (Translated Protein) 2.0 %Cys (Mature Protein) 1.7 %Met (Mature Protein) 3.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSMNKAVSSEQKPLDVICLGRVAVDLYGQQIGSRLEDMTTFAKYLGGSSGNVAYGTAIQG CCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHH LRSAMLARVGDEHMGRFVREELNRVGVDTQCLLSDRDRLTALVILGIKDQDTFPLIFYRD HHHHHHHHHCHHHHHHHHHHHHHHCCCCHHHHHCCCCCEEEEEEEEECCCCCCEEEEEEC NCADMALTPEDIREDYIASSRALAVTGTHLSHPNTRAAVLKALEYAQKHGLRRVLDIDYR CCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCHHHHCCCCC PVLWGLTSLGDGETRFIASSQVTEQLQQVLRHFDLIVGTEEEFHIAGGSTDTLTALRRVR HHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHH QLTQAVLVCKRGALGCSVFEGNIADDWSQVKIHSGVRVDVLNVLGAGDAFMSGLLRGYLN HHHHHHHHHHCCCCEEEEEECCCCCCCHHEEECCCCEEEHHHHHCCCHHHHHHHHHHHCC DESWEQACRYANACGALVVSRHGCAPAMPTKKELDDYLAREQSITRPDKDPRLNHLHRVT CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH TRKQHWPELCVFAFDHRKQLVDIANEVGASESAIPPLKMLLLEGARQAALEAGLQNNSGI HHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCE LADTTFGQQALNDVTGQGWWIGRPVEMPGSYPLKLEHGDIGSQLVSWPQEHVVKCLVFYH EEECCHHHHHHHHCCCCCEEECCCCCCCCCCCEEEECCCHHHHHHHCCHHHHHHHHHHHC PLDAESVRLEQEALIDEVYRACCQSGHDLLLEVILPRDTADQNEQYYPQIVERFYQLGIL CCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEHEEECCCCCCCCCCHHHHHHHHHHHCCCC PDWWKLPPLSPDRWREISQHIEHYDPECRGILILGLDAPESELKSGFAAAADMPWVKGFA CCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHCCHHHHCCCCHHHHHH VGRTIFGEPSRQWLGGQLNDEQLIATVKQKYRMLIDYWREYRPAR HCCHHCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC >Mature Secondary Structure SMNKAVSSEQKPLDVICLGRVAVDLYGQQIGSRLEDMTTFAKYLGGSSGNVAYGTAIQG CCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHH LRSAMLARVGDEHMGRFVREELNRVGVDTQCLLSDRDRLTALVILGIKDQDTFPLIFYRD HHHHHHHHHCHHHHHHHHHHHHHHCCCCHHHHHCCCCCEEEEEEEEECCCCCCEEEEEEC NCADMALTPEDIREDYIASSRALAVTGTHLSHPNTRAAVLKALEYAQKHGLRRVLDIDYR CCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCHHHHCCCCC PVLWGLTSLGDGETRFIASSQVTEQLQQVLRHFDLIVGTEEEFHIAGGSTDTLTALRRVR HHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHH QLTQAVLVCKRGALGCSVFEGNIADDWSQVKIHSGVRVDVLNVLGAGDAFMSGLLRGYLN HHHHHHHHHHCCCCEEEEEECCCCCCCHHEEECCCCEEEHHHHHCCCHHHHHHHHHHHCC DESWEQACRYANACGALVVSRHGCAPAMPTKKELDDYLAREQSITRPDKDPRLNHLHRVT CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH TRKQHWPELCVFAFDHRKQLVDIANEVGASESAIPPLKMLLLEGARQAALEAGLQNNSGI HHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCE LADTTFGQQALNDVTGQGWWIGRPVEMPGSYPLKLEHGDIGSQLVSWPQEHVVKCLVFYH EEECCHHHHHHHHCCCCCEEECCCCCCCCCCCEEEECCCHHHHHHHCCHHHHHHHHHHHC PLDAESVRLEQEALIDEVYRACCQSGHDLLLEVILPRDTADQNEQYYPQIVERFYQLGIL CCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEHEEECCCCCCCCCCHHHHHHHHHHHCCCC PDWWKLPPLSPDRWREISQHIEHYDPECRGILILGLDAPESELKSGFAAAADMPWVKGFA CCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHCCHHHHCCCCHHHHHH VGRTIFGEPSRQWLGGQLNDEQLIATVKQKYRMLIDYWREYRPAR HCCHHCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA