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The map label for this gene is dinF [H]

Identifier: 218551356

GI number: 218551356

Start: 4235823

End: 4237148

Strand: Direct

Name: dinF [H]

Synonym: EFER_4135

Alternate gene names: 218551356

Gene position: 4235823-4237148 (Clockwise)

Preceding gene: 218551355

Following gene: 218551357

Centisome position: 92.31

GC content: 52.34

Gene sequence:

>1326_bases
ATGGCATTCCTTACCTCATCTGATAAAGCACTCTGGCATCTTGCCTTACCCATGATCTTCTCCAATATCACCGTCCCGTT
ACTGGGTCTGGTCGATACGGCAGTTATTGGTCATCTTGATAGTCCGGTTTATTTGGGCGGTGTGGCTGTAGGGGCAACGG
CGACCAGCTTTCTCTTTATGTTGCTGTTGTTTTTGCGTATGAGCACCACCGGTCTTACCGCCCAGGCTTATGGTGCAAAA
AATCCTCAGGCTTTAGCACGAGCACTGGTGCAACCGCTGTTGCTGGCATTAGGGGCTGGAGCATTAATTGCTCTGTTACG
CACACCGATAATCGCTCTTGCTTTACATATTGTCGGTGGCAGTGAGGCTGTACTGGAACAGGCACGACGCTTTCTGGAAA
TCCGTTGGTTAAGTGCTCCGGCATCACTGGCTAATCTGGTATTACTTGGCTGGTTACTTGGCGTGCAATATGCCCGTGCG
CCGGTTGTTCTGCTGGTGGTCGGTAATATCCTCAACATTGTGCTCGATATCTGGCTGGTGATGGGGCTTCATATGAACGT
GCAGGGCGCGGCGCTGGCGACGGTTATTGCGGAATATGCAACATTGCTGATTGGTCTGCTAATGGTGCGTAAAATCCTCA
AACTACGCGGTATCTCCGGTGAAATGCTGAAAACAGCCTGGCGAGGCAACTTCCGCCGCCTGCTGGCACTTAACCGCGAT
ATCATGCTGCGTTCGTTATTGTTACAACTCTGTTTTGGCGCAATAACGGTTCTTGGCGCGCGACTGGGAAGTGACATTAT
CGCCGTCAACGCGGTCCTGATGACGCTACTCACCTTTACCGCCTATGCGCTGGATGGTTTTGCCTACGCGGTTGAAGCGC
ATTCAGGTCAGGCGTACGGTGCACGCGACGGGAGCCAGCTACTGGAGGTCTGGCGTGCAGCGTGCCGCCAGTCGGGGATC
GTAGCGTTGCTGTTTTCTGTGATTTATTTGCTGGCGGGTGAACATATCATTGCCTTACTGACCTCGTTAACCCAGATCCA
ACAACTGGCCGATCATTATCTTTTCTGGCAAGTCATTTTGCCGCTGGTGGGGGTCTGGTGTTATCTGCTGGATGGCATGT
TTATTGGTGCAACACGCGCCGCCGAAATGCGCAATAGTATGGCGGTCGCAGCAGCAGGATTCGCGCTTACGTTACTGACC
TTACCGTGGCTGGGTAATCATGGTTTGTGGCTGGCATTAACCGTATTTTTGGCACTGCGAGGGCTTTCTCTGGCTTATAT
CTGGCGTCGTCACTGGTGTAATGGCACTTGGTTTGCAGAAACGTGA

Upstream 100 bases:

>100_bases
CGTAATTCGCAACGGCGACTGGCTGTAATCAAGCTTTTAATACCGCGATGCATCAGGCATCGCGGTCTGTTTTTCACTTC
TTCTCATCAGGCTTGTCTGC

Downstream 100 bases:

>100_bases
TGGTTAAAAATTCTGATAAATAATTCTGATTCCAGATTCCTGACTACACTTAATCTCACGTTCAGCAGAAAACATAGCGA
TGTTGGACGCGACACTCTCG

Product: DNA-damage-inducible SOS response protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 440

Protein sequence:

>441_residues
MAFLTSSDKALWHLALPMIFSNITVPLLGLVDTAVIGHLDSPVYLGGVAVGATATSFLFMLLLFLRMSTTGLTAQAYGAK
NPQALARALVQPLLLALGAGALIALLRTPIIALALHIVGGSEAVLEQARRFLEIRWLSAPASLANLVLLGWLLGVQYARA
PVVLLVVGNILNIVLDIWLVMGLHMNVQGAALATVIAEYATLLIGLLMVRKILKLRGISGEMLKTAWRGNFRRLLALNRD
IMLRSLLLQLCFGAITVLGARLGSDIIAVNAVLMTLLTFTAYALDGFAYAVEAHSGQAYGARDGSQLLEVWRAACRQSGI
VALLFSVIYLLAGEHIIALLTSLTQIQQLADHYLFWQVILPLVGVWCYLLDGMFIGATRAAEMRNSMAVAAAGFALTLLT
LPWLGNHGLWLALTVFLALRGLSLAYIWRRHWCNGTWFAET

Sequences:

>Translated_441_residues
MAFLTSSDKALWHLALPMIFSNITVPLLGLVDTAVIGHLDSPVYLGGVAVGATATSFLFMLLLFLRMSTTGLTAQAYGAK
NPQALARALVQPLLLALGAGALIALLRTPIIALALHIVGGSEAVLEQARRFLEIRWLSAPASLANLVLLGWLLGVQYARA
PVVLLVVGNILNIVLDIWLVMGLHMNVQGAALATVIAEYATLLIGLLMVRKILKLRGISGEMLKTAWRGNFRRLLALNRD
IMLRSLLLQLCFGAITVLGARLGSDIIAVNAVLMTLLTFTAYALDGFAYAVEAHSGQAYGARDGSQLLEVWRAACRQSGI
VALLFSVIYLLAGEHIIALLTSLTQIQQLADHYLFWQVILPLVGVWCYLLDGMFIGATRAAEMRNSMAVAAAGFALTLLT
LPWLGNHGLWLALTVFLALRGLSLAYIWRRHWCNGTWFAET
>Mature_440_residues
AFLTSSDKALWHLALPMIFSNITVPLLGLVDTAVIGHLDSPVYLGGVAVGATATSFLFMLLLFLRMSTTGLTAQAYGAKN
PQALARALVQPLLLALGAGALIALLRTPIIALALHIVGGSEAVLEQARRFLEIRWLSAPASLANLVLLGWLLGVQYARAP
VVLLVVGNILNIVLDIWLVMGLHMNVQGAALATVIAEYATLLIGLLMVRKILKLRGISGEMLKTAWRGNFRRLLALNRDI
MLRSLLLQLCFGAITVLGARLGSDIIAVNAVLMTLLTFTAYALDGFAYAVEAHSGQAYGARDGSQLLEVWRAACRQSGIV
ALLFSVIYLLAGEHIIALLTSLTQIQQLADHYLFWQVILPLVGVWCYLLDGMFIGATRAAEMRNSMAVAAAGFALTLLTL
PWLGNHGLWLALTVFLALRGLSLAYIWRRHWCNGTWFAET

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790477, Length=441, Percent_Identity=96.8253968253968, Blast_Score=767, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 47762; Mature: 47631

Theoretical pI: Translated: 9.67; Mature: 9.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFLTSSDKALWHLALPMIFSNITVPLLGLVDTAVIGHLDSPVYLGGVAVGATATSFLFM
CCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCHHHHHHHHHHHH
LLLFLRMSTTGLTAQAYGAKNPQALARALVQPLLLALGAGALIALLRTPIIALALHIVGG
HHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SEAVLEQARRFLEIRWLSAPASLANLVLLGWLLGVQYARAPVVLLVVGNILNIVLDIWLV
CHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
MGLHMNVQGAALATVIAEYATLLIGLLMVRKILKLRGISGEMLKTAWRGNFRRLLALNRD
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHH
IMLRSLLLQLCFGAITVLGARLGSDIIAVNAVLMTLLTFTAYALDGFAYAVEAHSGQAYG
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCC
ARDGSQLLEVWRAACRQSGIVALLFSVIYLLAGEHIIALLTSLTQIQQLADHYLFWQVIL
CCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PLVGVWCYLLDGMFIGATRAAEMRNSMAVAAAGFALTLLTLPWLGNHGLWLALTVFLALR
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
GLSLAYIWRRHWCNGTWFAET
HHHHHHHHHHHCCCCCEECCC
>Mature Secondary Structure 
AFLTSSDKALWHLALPMIFSNITVPLLGLVDTAVIGHLDSPVYLGGVAVGATATSFLFM
CEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCHHHHHHHHHHHH
LLLFLRMSTTGLTAQAYGAKNPQALARALVQPLLLALGAGALIALLRTPIIALALHIVGG
HHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SEAVLEQARRFLEIRWLSAPASLANLVLLGWLLGVQYARAPVVLLVVGNILNIVLDIWLV
CHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
MGLHMNVQGAALATVIAEYATLLIGLLMVRKILKLRGISGEMLKTAWRGNFRRLLALNRD
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHH
IMLRSLLLQLCFGAITVLGARLGSDIIAVNAVLMTLLTFTAYALDGFAYAVEAHSGQAYG
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCC
ARDGSQLLEVWRAACRQSGIVALLFSVIYLLAGEHIIALLTSLTQIQQLADHYLFWQVIL
CCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PLVGVWCYLLDGMFIGATRAAEMRNSMAVAAAGFALTLLTLPWLGNHGLWLALTVFLALR
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
GLSLAYIWRRHWCNGTWFAET
HHHHHHHHHHHCCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503 [H]