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The map label for this gene is yidC [H]

Identifier: 218551236

GI number: 218551236

Start: 4104903

End: 4106549

Strand: Direct

Name: yidC [H]

Synonym: EFER_4002

Alternate gene names: 218551236

Gene position: 4104903-4106549 (Clockwise)

Preceding gene: 218551235

Following gene: 218551237

Centisome position: 89.46

GC content: 53.55

Gene sequence:

>1647_bases
ATGGATTCGCAACGCAATCTTTTAGTCATCGCTTTGCTGTTCGTGTCTTTCATGATCTGGCAAGCCTGGGAGCAGGATAA
AAACCCGCAACCTCAGGCCCAACAGACCACGCAGACAACGACCACCGCAGCGGGTAGCGCCGCCGACCAGGGCGTACCGG
CCAGTGGCCAGGGGAAACTGATCTCGGTTAAGACCGACGTGCTTGATCTGACCATCAACACCCGTGGTGGTGATGTTGAG
CAAGCTCTGCTGCCTGCTTACCCGAAAGAGCTGAACTCTACCCAGCCGTTCCAGCTGCTGGAAACTTCACCGCAGTTTAT
TTATCAGGCACAGAGCGGTCTGACCGGTCGTGATGGCCCGGATAACCCGGCTAACGGCCCGCGTCCGCTGTATAACGTTG
AAAAAGACGCTTATGTGCTGGCTGAAGGTCAAAACGAACTGCAGGTGCCGATGACGTATACCGACGCGGCAGGCAACACG
TTTACCAAAACGTTTATCCTGAAACGTGGTGATTACGCTGTCAACGTCAACTACAACGTGCAGAACGCTGGCGAGAAACC
GCTGGAGATCTCCACCTTTGGTCAGTTGAAGCAATCCATTACACTGCCACCGTATCTCGACACCGGAAGCAGCAACTTCG
CACTGCACACCTTCCGTGGCGCGGCGTACTCCACGCCTGACGAGAAGTACGAGAAATATAAGTTTGATACCATTGCCGAT
AACGAAAACCTGAACATCTCTTCGAAAGGTGGTTGGGTGGCGATGCTGCAACAGTATTTCGCGACTGCGTGGATCCCGCA
TAACGACGGTACCAACAACTTCTACACCGCTAATCTGGGTAACGGCATCGCCGCTATCGGCTATAAATCTCAGCCGGTAC
TGGTTCAGCCTGGTCAGACTGGCGCAATGAACAGCACCCTGTGGGTTGGCCCGGAAATCCAGGACAAAATGGCAGCAGTT
GCTCCGCACCTGGATCTGACCGTTGATTACGGTTGGTTGTGGTTCATCTCTCAGCCGCTGTTCAAACTGCTGAAATGGAT
CCATAGCTTTGTGGGTAACTGGGGCTTCTCCATTATCATCATCACCTTTATCGTTCGTGGCATCATGTACCCGCTGACCA
AAGCGCAGTACACCTCCATGGCGAAGATGCGTATGCTGCAGCCGAAGATTCAGGCGATGCGTGAGCGTCTGGGCGATGAC
AAACAGCGTATCAGCCAGGAAATGATGGCGCTGTACAAAGCTGAGAAGGTTAACCCGCTGGGCGGCTGCTTCCCGCTGCT
GATCCAGATGCCAATCTTCCTGGCGTTGTACTACATGCTGATGGGTTCTGTTGAACTGCGTCAGGCACCGTTTGCACTGT
GGATCCACGACCTGTCAGCACAGGACCCGTACTACATCCTGCCGATCCTGATGGGCGTAACGATGTTCTTCATTCAGAAG
ATGTCGCCGACCACTGTGACCGACCCGATGCAGCAGAAGATCATGACCTTTATGCCGGTCATCTTCACCGTGTTCTTCCT
GTGGTTCCCGTCAGGTCTGGTGCTGTACTATATCGTCAGCAACCTGGTTACCATTATTCAGCAGCAGCTGATTTACCGTG
GTCTGGAAAAACGTGGCCTGCATAGCCGCGAGAAGAAAAAATCCTGA

Upstream 100 bases:

>100_bases
GTTGGTTGACGGTGAAACGCGTATTAAAATGCCACCCTTTACACCCTGGTGGTGACGATCCCGTCCCGCCCGGACCATTT
GATACCAGAGAACACTAACG

Downstream 100 bases:

>100_bases
TTCGGTGAGTTTTCGCTAAAATAAGGGCGGTCAGTTGACCGCCTTTTTTCTTTTCGTAGGGCGGATAAGCACCGCGCATC
CGCCACACAAAGCAACAGGA

Product: inner membrane protein translocase component YidC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 548; Mature: 548

Protein sequence:

>548_residues
MDSQRNLLVIALLFVSFMIWQAWEQDKNPQPQAQQTTQTTTTAAGSAADQGVPASGQGKLISVKTDVLDLTINTRGGDVE
QALLPAYPKELNSTQPFQLLETSPQFIYQAQSGLTGRDGPDNPANGPRPLYNVEKDAYVLAEGQNELQVPMTYTDAAGNT
FTKTFILKRGDYAVNVNYNVQNAGEKPLEISTFGQLKQSITLPPYLDTGSSNFALHTFRGAAYSTPDEKYEKYKFDTIAD
NENLNISSKGGWVAMLQQYFATAWIPHNDGTNNFYTANLGNGIAAIGYKSQPVLVQPGQTGAMNSTLWVGPEIQDKMAAV
APHLDLTVDYGWLWFISQPLFKLLKWIHSFVGNWGFSIIIITFIVRGIMYPLTKAQYTSMAKMRMLQPKIQAMRERLGDD
KQRISQEMMALYKAEKVNPLGGCFPLLIQMPIFLALYYMLMGSVELRQAPFALWIHDLSAQDPYYILPILMGVTMFFIQK
MSPTTVTDPMQQKIMTFMPVIFTVFFLWFPSGLVLYYIVSNLVTIIQQQLIYRGLEKRGLHSREKKKS

Sequences:

>Translated_548_residues
MDSQRNLLVIALLFVSFMIWQAWEQDKNPQPQAQQTTQTTTTAAGSAADQGVPASGQGKLISVKTDVLDLTINTRGGDVE
QALLPAYPKELNSTQPFQLLETSPQFIYQAQSGLTGRDGPDNPANGPRPLYNVEKDAYVLAEGQNELQVPMTYTDAAGNT
FTKTFILKRGDYAVNVNYNVQNAGEKPLEISTFGQLKQSITLPPYLDTGSSNFALHTFRGAAYSTPDEKYEKYKFDTIAD
NENLNISSKGGWVAMLQQYFATAWIPHNDGTNNFYTANLGNGIAAIGYKSQPVLVQPGQTGAMNSTLWVGPEIQDKMAAV
APHLDLTVDYGWLWFISQPLFKLLKWIHSFVGNWGFSIIIITFIVRGIMYPLTKAQYTSMAKMRMLQPKIQAMRERLGDD
KQRISQEMMALYKAEKVNPLGGCFPLLIQMPIFLALYYMLMGSVELRQAPFALWIHDLSAQDPYYILPILMGVTMFFIQK
MSPTTVTDPMQQKIMTFMPVIFTVFFLWFPSGLVLYYIVSNLVTIIQQQLIYRGLEKRGLHSREKKKS
>Mature_548_residues
MDSQRNLLVIALLFVSFMIWQAWEQDKNPQPQAQQTTQTTTTAAGSAADQGVPASGQGKLISVKTDVLDLTINTRGGDVE
QALLPAYPKELNSTQPFQLLETSPQFIYQAQSGLTGRDGPDNPANGPRPLYNVEKDAYVLAEGQNELQVPMTYTDAAGNT
FTKTFILKRGDYAVNVNYNVQNAGEKPLEISTFGQLKQSITLPPYLDTGSSNFALHTFRGAAYSTPDEKYEKYKFDTIAD
NENLNISSKGGWVAMLQQYFATAWIPHNDGTNNFYTANLGNGIAAIGYKSQPVLVQPGQTGAMNSTLWVGPEIQDKMAAV
APHLDLTVDYGWLWFISQPLFKLLKWIHSFVGNWGFSIIIITFIVRGIMYPLTKAQYTSMAKMRMLQPKIQAMRERLGDD
KQRISQEMMALYKAEKVNPLGGCFPLLIQMPIFLALYYMLMGSVELRQAPFALWIHDLSAQDPYYILPILMGVTMFFIQK
MSPTTVTDPMQQKIMTFMPVIFTVFFLWFPSGLVLYYIVSNLVTIIQQQLIYRGLEKRGLHSREKKKS

Specific function: Required for the insertion of integral membrane proteins into the membrane. Probably plays an essential role in the integration of proteins of the respiratory chain complexes. Involved in integration of membrane proteins that insert dependently and indepe

COG id: COG0706

COG function: function code U; Preprotein translocase subunit YidC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OXA1/oxaA family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790140, Length=548, Percent_Identity=99.4525547445255, Blast_Score=1125, Evalue=0.0,
Organism=Drosophila melanogaster, GI24662345, Length=196, Percent_Identity=26.0204081632653, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21356443, Length=196, Percent_Identity=26.0204081632653, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019998
- InterPro:   IPR001708 [H]

Pfam domain/function: PF02096 60KD_IMP [H]

EC number: NA

Molecular weight: Translated: 61581; Mature: 61581

Theoretical pI: Translated: 8.25; Mature: 8.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSQRNLLVIALLFVSFMIWQAWEQDKNPQPQAQQTTQTTTTAAGSAADQGVPASGQGKL
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCE
ISVKTDVLDLTINTRGGDVEQALLPAYPKELNSTQPFQLLETSPQFIYQAQSGLTGRDGP
EEEEEEEEEEEEECCCCCHHHHHHCCCHHHCCCCCCHHHHHCCHHHHHHHHCCCCCCCCC
DNPANGPRPLYNVEKDAYVLAEGQNELQVPMTYTDAAGNTFTKTFILKRGDYAVNVNYNV
CCCCCCCCCCCCCCCCEEEEECCCCCEEEEEEEECCCCCCEEEEEEEECCCEEEEEEEEE
QNAGEKPLEISTFGQLKQSITLPPYLDTGSSNFALHTFRGAAYSTPDEKYEKYKFDTIAD
CCCCCCCEEEHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHEECCEECC
NENLNISSKGGWVAMLQQYFATAWIPHNDGTNNFYTANLGNGIAAIGYKSQPVLVQPGQT
CCCCEECCCCCHHHHHHHHHHHEECCCCCCCCCEEEEECCCCEEEECCCCCCEEECCCCC
GAMNSTLWVGPEIQDKMAAVAPHLDLTVDYGWLWFISQPLFKLLKWIHSFVGNWGFSIII
CCCCCEEEECCCHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
ITFIVRGIMYPLTKAQYTSMAKMRMLQPKIQAMRERLGDDKQRISQEMMALYKAEKVNPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCC
GGCFPLLIQMPIFLALYYMLMGSVELRQAPFALWIHDLSAQDPYYILPILMGVTMFFIQK
CHHHHHHHHHHHHHHHHHHHHCCHHHHHCCEEEEEEECCCCCCEEHHHHHHHHHHHHHHH
MSPTTVTDPMQQKIMTFMPVIFTVFFLWFPSGLVLYYIVSNLVTIIQQQLIYRGLEKRGL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
HSREKKKS
CCHHHCCC
>Mature Secondary Structure
MDSQRNLLVIALLFVSFMIWQAWEQDKNPQPQAQQTTQTTTTAAGSAADQGVPASGQGKL
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCE
ISVKTDVLDLTINTRGGDVEQALLPAYPKELNSTQPFQLLETSPQFIYQAQSGLTGRDGP
EEEEEEEEEEEEECCCCCHHHHHHCCCHHHCCCCCCHHHHHCCHHHHHHHHCCCCCCCCC
DNPANGPRPLYNVEKDAYVLAEGQNELQVPMTYTDAAGNTFTKTFILKRGDYAVNVNYNV
CCCCCCCCCCCCCCCCEEEEECCCCCEEEEEEEECCCCCCEEEEEEEECCCEEEEEEEEE
QNAGEKPLEISTFGQLKQSITLPPYLDTGSSNFALHTFRGAAYSTPDEKYEKYKFDTIAD
CCCCCCCEEEHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHEECCEECC
NENLNISSKGGWVAMLQQYFATAWIPHNDGTNNFYTANLGNGIAAIGYKSQPVLVQPGQT
CCCCEECCCCCHHHHHHHHHHHEECCCCCCCCCEEEEECCCCEEEECCCCCCEEECCCCC
GAMNSTLWVGPEIQDKMAAVAPHLDLTVDYGWLWFISQPLFKLLKWIHSFVGNWGFSIII
CCCCCEEEECCCHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
ITFIVRGIMYPLTKAQYTSMAKMRMLQPKIQAMRERLGDDKQRISQEMMALYKAEKVNPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCC
GGCFPLLIQMPIFLALYYMLMGSVELRQAPFALWIHDLSAQDPYYILPILMGVTMFFIQK
CHHHHHHHHHHHHHHHHHHHHCCHHHHHCCEEEEEEECCCCCCEEHHHHHHHHHHHHHHH
MSPTTVTDPMQQKIMTFMPVIFTVFFLWFPSGLVLYYIVSNLVTIIQQQLIYRGLEKRGL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
HSREKKKS
CCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA