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The map label for this gene is dsdA [H]

Identifier: 218551208

GI number: 218551208

Start: 4077773

End: 4079101

Strand: Direct

Name: dsdA [H]

Synonym: EFER_3973

Alternate gene names: 218551208

Gene position: 4077773-4079101 (Clockwise)

Preceding gene: 218551207

Following gene: 218551214

Centisome position: 88.87

GC content: 51.02

Gene sequence:

>1329_bases
ATGGAAAACGCTAAAATGAACTCGCTCATCGCCCAGTATCCGTTGGTAAAGGATCTGGTTGCTCTTAAAGAAACCACCTG
GTTCAATCCTGGCACGACCTCATTGGCTGAAGGTTTACCTTATGTTGGCCTGACCGAACAGGATGTTCAGGACGCCCATG
CGCGCTTATCTCGTTTTGCCCCCTATCTGGCAAAAGCATTTCCTGAAACTGCTGCCTCTGGGGGGATTATTGAATCAGAA
CTGGCTGCCATTCCGGCTATGCAAAAACGGCTGGAAAAGGAATATCAGCAACCGATCAGCGGGCAACTGTTACTGAAAAA
AGATAGCCATTTGCCTATTTCCGGCTCCATAAAAGCACGCGGCGGGATTTATGAAGTCCTGGCACATGCAGAAAAACTGG
CTCTGGAAGCAGGATTGCTGACGCTTGAAGATGACTACAGCAAACTGCTTTCTCCGGAGTTTAAACAGTTCTTTAGCCAA
TACAGCATTGCTGTGGGCTCAACCGGAAATCTGGGGTTATCAATCGGTATTATGAGCGCCCGCATTGGCTTTAAGGTGAC
AGTGCATATGTCTGCTGATGCCCGGGCATGGAAAAAAGCGAAACTGCGCAGCCATGGCGTTACGGTCGTGGAATATGAGC
AAGATTATGGTGTTGCTGTCGAGGAAGGACGTAAAGCAGCGCAGTCTGACCCGAACTGTTTCTTTATTGATGACGAGAAT
TCCCGCACGTTGTTCCTTGGGTATTCCGTCGCAGGCCAGCGTCTAAAAGCGCAATTTGCTCAGCAAGGTCGTATCGTCGA
TGCTGATAACCCTCTGTTTGTCTATCTGCCGTGTGGTGTTGGCGGTGGTCCTGGTGGCGTCGCATTCGGTCTTAAACTGG
CGTTTGGCGATCATGTTCACTGCTTTTTTGCCGAACCAACGCACTCCCCTTGTATGCTGTTAGGCGTCCATACTGGATTA
CACGATCAGATTTCTGTTCAGGATATTGGTATCGACAACCTTACCGCCGCGGATGGCCTTGCAGTTGGTCGCGCATCAGG
CTTTGTCGGGCGGGCAATGGAGCGTCTGCTGGATGGCTTCTATACCCTTAGCGATCAAACCATGTATGACATGCTTGGCT
GGCTGGCGCAGGAAGAAGGGATTCGTCTTGAACCTTCAGCACTGGCGGGTATGGCCGGGCCTCAGCGCGTGTGCGCATCA
GTAAGTTACCAACAGATACACGGTTTCAGCGCCGAACAACTGCGTAATGCCACTCATCTGGTGTGGGCGACGGGAGGTGG
AATGGTGCCGGAAGAAGAGATGAATCAATATCTGGCTAAAGGCCGTTAA

Upstream 100 bases:

>100_bases
CATTTAAATACTATACGACAGCGACATTTATCGCTTCAGTCGTCGCTCTGGCGGGCACATTCCTGCTGTCATTTATCATC
TAAGCGCAAAGAGACGTACT

Downstream 100 bases:

>100_bases
TAACGTTTCAACGCAGCATCGCCATCAGTTCCAATGGGGAGCGGTGCTGCTTGATTAGGTCCCGCAGTACTCGCATATAA
GGTGAGCTATGTTCAAAAAA

Product: D-serine dehydratase

Products: NA

Alternate protein names: D-serine deaminase; DSD [H]

Number of amino acids: Translated: 442; Mature: 442

Protein sequence:

>442_residues
MENAKMNSLIAQYPLVKDLVALKETTWFNPGTTSLAEGLPYVGLTEQDVQDAHARLSRFAPYLAKAFPETAASGGIIESE
LAAIPAMQKRLEKEYQQPISGQLLLKKDSHLPISGSIKARGGIYEVLAHAEKLALEAGLLTLEDDYSKLLSPEFKQFFSQ
YSIAVGSTGNLGLSIGIMSARIGFKVTVHMSADARAWKKAKLRSHGVTVVEYEQDYGVAVEEGRKAAQSDPNCFFIDDEN
SRTLFLGYSVAGQRLKAQFAQQGRIVDADNPLFVYLPCGVGGGPGGVAFGLKLAFGDHVHCFFAEPTHSPCMLLGVHTGL
HDQISVQDIGIDNLTAADGLAVGRASGFVGRAMERLLDGFYTLSDQTMYDMLGWLAQEEGIRLEPSALAGMAGPQRVCAS
VSYQQIHGFSAEQLRNATHLVWATGGGMVPEEEMNQYLAKGR

Sequences:

>Translated_442_residues
MENAKMNSLIAQYPLVKDLVALKETTWFNPGTTSLAEGLPYVGLTEQDVQDAHARLSRFAPYLAKAFPETAASGGIIESE
LAAIPAMQKRLEKEYQQPISGQLLLKKDSHLPISGSIKARGGIYEVLAHAEKLALEAGLLTLEDDYSKLLSPEFKQFFSQ
YSIAVGSTGNLGLSIGIMSARIGFKVTVHMSADARAWKKAKLRSHGVTVVEYEQDYGVAVEEGRKAAQSDPNCFFIDDEN
SRTLFLGYSVAGQRLKAQFAQQGRIVDADNPLFVYLPCGVGGGPGGVAFGLKLAFGDHVHCFFAEPTHSPCMLLGVHTGL
HDQISVQDIGIDNLTAADGLAVGRASGFVGRAMERLLDGFYTLSDQTMYDMLGWLAQEEGIRLEPSALAGMAGPQRVCAS
VSYQQIHGFSAEQLRNATHLVWATGGGMVPEEEMNQYLAKGR
>Mature_442_residues
MENAKMNSLIAQYPLVKDLVALKETTWFNPGTTSLAEGLPYVGLTEQDVQDAHARLSRFAPYLAKAFPETAASGGIIESE
LAAIPAMQKRLEKEYQQPISGQLLLKKDSHLPISGSIKARGGIYEVLAHAEKLALEAGLLTLEDDYSKLLSPEFKQFFSQ
YSIAVGSTGNLGLSIGIMSARIGFKVTVHMSADARAWKKAKLRSHGVTVVEYEQDYGVAVEEGRKAAQSDPNCFFIDDEN
SRTLFLGYSVAGQRLKAQFAQQGRIVDADNPLFVYLPCGVGGGPGGVAFGLKLAFGDHVHCFFAEPTHSPCMLLGVHTGL
HDQISVQDIGIDNLTAADGLAVGRASGFVGRAMERLLDGFYTLSDQTMYDMLGWLAQEEGIRLEPSALAGMAGPQRVCAS
VSYQQIHGFSAEQLRNATHLVWATGGGMVPEEEMNQYLAKGR

Specific function: Unknown

COG id: COG3048

COG function: function code E; D-serine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serine/threonine dehydratase family. DsdA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788708, Length=442, Percent_Identity=98.868778280543, Blast_Score=904, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011780
- InterPro:   IPR001926
- InterPro:   IPR000634 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.3.1.18 [H]

Molecular weight: Translated: 47825; Mature: 47825

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: PS00165 DEHYDRATASE_SER_THR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENAKMNSLIAQYPLVKDLVALKETTWFNPGTTSLAEGLPYVGLTEQDVQDAHARLSRFA
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHH
PYLAKAFPETAASGGIIESELAAIPAMQKRLEKEYQQPISGQLLLKKDSHLPISGSIKAR
HHHHHHCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCC
GGIYEVLAHAEKLALEAGLLTLEDDYSKLLSPEFKQFFSQYSIAVGSTGNLGLSIGIMSA
CCHHHHHHHHHHHHHHHCCEEECCHHHHHCCHHHHHHHHHHEEEECCCCCCEEEEEEEEE
RIGFKVTVHMSADARAWKKAKLRSHGVTVVEYEQDYGVAVEEGRKAAQSDPNCFFIDDEN
ECCEEEEEEECCCHHHHHHHHHHHCCCEEEEECCCCCCCHHHCCHHHCCCCCEEEEECCC
SRTLFLGYSVAGQRLKAQFAQQGRIVDADNPLFVYLPCGVGGGPGGVAFGLKLAFGDHVH
CCEEEEEEHHHHHHHHHHHHHCCCEEECCCCEEEEEECCCCCCCCCCEEEEEEEECCEEE
CFFAEPTHSPCMLLGVHTGLHDQISVQDIGIDNLTAADGLAVGRASGFVGRAMERLLDGF
EEEECCCCCCEEEEEECCCCCCCEEEEECCCCCCCCCCCCEECCCCCHHHHHHHHHHHHH
YTLSDQTMYDMLGWLAQEEGIRLEPSALAGMAGPQRVCASVSYQQIHGFSAEQLRNATHL
EECCCCHHHHHHHHHHHCCCCEECHHHHHCCCCHHHHHHHCCHHHHCCCCHHHHCCCEEE
VWATGGGMVPEEEMNQYLAKGR
EEECCCCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MENAKMNSLIAQYPLVKDLVALKETTWFNPGTTSLAEGLPYVGLTEQDVQDAHARLSRFA
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHH
PYLAKAFPETAASGGIIESELAAIPAMQKRLEKEYQQPISGQLLLKKDSHLPISGSIKAR
HHHHHHCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCC
GGIYEVLAHAEKLALEAGLLTLEDDYSKLLSPEFKQFFSQYSIAVGSTGNLGLSIGIMSA
CCHHHHHHHHHHHHHHHCCEEECCHHHHHCCHHHHHHHHHHEEEECCCCCCEEEEEEEEE
RIGFKVTVHMSADARAWKKAKLRSHGVTVVEYEQDYGVAVEEGRKAAQSDPNCFFIDDEN
ECCEEEEEEECCCHHHHHHHHHHHCCCEEEEECCCCCCCHHHCCHHHCCCCCEEEEECCC
SRTLFLGYSVAGQRLKAQFAQQGRIVDADNPLFVYLPCGVGGGPGGVAFGLKLAFGDHVH
CCEEEEEEHHHHHHHHHHHHHCCCEEECCCCEEEEEECCCCCCCCCCEEEEEEEECCEEE
CFFAEPTHSPCMLLGVHTGLHDQISVQDIGIDNLTAADGLAVGRASGFVGRAMERLLDGF
EEEECCCCCCEEEEEECCCCCCCEEEEECCCCCCCCCCCCEECCCCCHHHHHHHHHHHHH
YTLSDQTMYDMLGWLAQEEGIRLEPSALAGMAGPQRVCASVSYQQIHGFSAEQLRNATHL
EECCCCHHHHHHHHHHHCCCCEECHHHHHCCCCHHHHHHHCCHHHHCCCCHHHHCCCEEE
VWATGGGMVPEEEMNQYLAKGR
EEECCCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA