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The map label for this gene is waaC [H]

Identifier: 218551149

GI number: 218551149

Start: 4011448

End: 4012404

Strand: Direct

Name: waaC [H]

Synonym: EFER_3910

Alternate gene names: 218551149

Gene position: 4011448-4012404 (Clockwise)

Preceding gene: 218551148

Following gene: 218551150

Centisome position: 87.42

GC content: 51.1

Gene sequence:

>957_bases
ATGCGGGTTCTGATCGTTAAAACATCGTCGATGGGCGATGTTCTCCATACGCTGCCCGCACTCACTGATGCCCAGCAGGT
AATCCCGGGGATTAAGTTTGACTGGGTGGTGGAAGAAGGATTTGCACAAATTCCTTCCTGGCACGCCGCCGTTGAGCGGG
TTATTCCTGTGGCAATACGCCGCTGGCGTAAAGCGTGGTTCTCGGCTCCCATAAAAGCAGAACGGAAAGCGTTTCGTGAG
GCACTACAAGCAGAAAACTATGACGCAGTTATCGACGCCCAGGGGTTGGTAAAAAGCGCGGCGCTGGTGACTCGTCTGGC
GCATGGCGTAAAGCATGGAATGGACTGGCAAACCGCTCGCGAACCACTGGCAAGCTTGTTTTACAATCGTAAGCATCATA
TTGCAAAACAGCAGCACGCCGTAGAGCGAACCCGGGAGTTGTTCGCCAAAAGTCTGGGCTATAGCAAACCGCAGACTCAG
GGCGATTATGCCATTGCGCAGCATTTCCTGACGAACCTGCCGACAGATGCTGGCAAATATGCCGTATTTCTTCATGCAAC
AACCCGTGATGATAAACACTGGCCGGAAACACACTGGCGAGAGTTGATTGGTTTACTGGCAGATTCAGGGATTCGCATTA
AACTTCCGTGGGGCGCGCCGCATGAAGAAGAGCGGGCAAAAAGACTGGCGGAAGGATTTGATTATGTCGACGTATTGCCG
AAGATGAGTCTGGAAGGCGTAGCTCGTGTGCTGGCGGGCGCTAAATTTGTTGTGTCAGTCGATACAGGGTTAAGCCATTT
AACTGCAGCACTGGATAGACCGAATATCACGGTTTATGGGCCAACCGATCCGGGATTAATTGGCGGATATGGGAAGAATC
AGGTGGTTTGTAGGGCGCCAGATAAAGATCTTGCTTATCTGACTGCAGAAACGGTATTTAATAAAATCAATTCCTGA

Upstream 100 bases:

>100_bases
TGACGCTGCGGAAGGTTATCACCAGAGCTTGATCGATATTACTCCCCAGCGCGTACTGGAAGAACTCAACGCGCTATTGT
TACAAGAGGAAGCCTGACGG

Downstream 100 bases:

>100_bases
TTAATACGTTATATATTATTTAAGATGGTGGAGAAGCAATGTTAACAGCCTCGCTGGCGCTACGTAATAAAGAAAACTGG
AAACCGCACTGGAATAAAGC

Product: ADP-heptose:LPS heptosyl transferase I

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MRVLIVKTSSMGDVLHTLPALTDAQQVIPGIKFDWVVEEGFAQIPSWHAAVERVIPVAIRRWRKAWFSAPIKAERKAFRE
ALQAENYDAVIDAQGLVKSAALVTRLAHGVKHGMDWQTAREPLASLFYNRKHHIAKQQHAVERTRELFAKSLGYSKPQTQ
GDYAIAQHFLTNLPTDAGKYAVFLHATTRDDKHWPETHWRELIGLLADSGIRIKLPWGAPHEEERAKRLAEGFDYVDVLP
KMSLEGVARVLAGAKFVVSVDTGLSHLTAALDRPNITVYGPTDPGLIGGYGKNQVVCRAPDKDLAYLTAETVFNKINS

Sequences:

>Translated_318_residues
MRVLIVKTSSMGDVLHTLPALTDAQQVIPGIKFDWVVEEGFAQIPSWHAAVERVIPVAIRRWRKAWFSAPIKAERKAFRE
ALQAENYDAVIDAQGLVKSAALVTRLAHGVKHGMDWQTAREPLASLFYNRKHHIAKQQHAVERTRELFAKSLGYSKPQTQ
GDYAIAQHFLTNLPTDAGKYAVFLHATTRDDKHWPETHWRELIGLLADSGIRIKLPWGAPHEEERAKRLAEGFDYVDVLP
KMSLEGVARVLAGAKFVVSVDTGLSHLTAALDRPNITVYGPTDPGLIGGYGKNQVVCRAPDKDLAYLTAETVFNKINS
>Mature_318_residues
MRVLIVKTSSMGDVLHTLPALTDAQQVIPGIKFDWVVEEGFAQIPSWHAAVERVIPVAIRRWRKAWFSAPIKAERKAFRE
ALQAENYDAVIDAQGLVKSAALVTRLAHGVKHGMDWQTAREPLASLFYNRKHHIAKQQHAVERTRELFAKSLGYSKPQTQ
GDYAIAQHFLTNLPTDAGKYAVFLHATTRDDKHWPETHWRELIGLLADSGIRIKLPWGAPHEEERAKRLAEGFDYVDVLP
KMSLEGVARVLAGAKFVVSVDTGLSHLTAALDRPNITVYGPTDPGLIGGYGKNQVVCRAPDKDLAYLTAETVFNKINS

Specific function: Heptose transfer to the lipopolysaccharide core. It transfers the innnermost heptose to [4'-P](3-deoxy-D-manno- octulosonic acid)2-IVA [H]

COG id: COG0859

COG function: function code M; ADP-heptose:LPS heptosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 9 family [H]

Homologues:

Organism=Escherichia coli, GI1790051, Length=318, Percent_Identity=94.0251572327044, Blast_Score=619, Evalue=1e-179,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002201
- InterPro:   IPR011908 [H]

Pfam domain/function: PF01075 Glyco_transf_9 [H]

EC number: 2.4.1.-

Molecular weight: Translated: 35442; Mature: 35442

Theoretical pI: Translated: 9.57; Mature: 9.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLIVKTSSMGDVLHTLPALTDAQQVIPGIKFDWVVEEGFAQIPSWHAAVERVIPVAIR
CEEEEEECCCHHHHHHHHHHHCCHHHHHCCCCEEEEEHHHHHHCCHHHHHHHHHHHHHHH
RWRKAWFSAPIKAERKAFREALQAENYDAVIDAQGLVKSAALVTRLAHGVKHGMDWQTAR
HHHHHHHCCCHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHHHHHHHHHCCCCHHHHH
EPLASLFYNRKHHIAKQQHAVERTRELFAKSLGYSKPQTQGDYAIAQHFLTNLPTDAGKY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCE
AVFLHATTRDDKHWPETHWRELIGLLADSGIRIKLPWGAPHEEERAKRLAEGFDYVDVLP
EEEEEEECCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHCCCHHHHHH
KMSLEGVARVLAGAKFVVSVDTGLSHLTAALDRPNITVYGPTDPGLIGGYGKNQVVCRAP
CCCHHHHHHHHCCCEEEEEECCCHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCEEEECC
DKDLAYLTAETVFNKINS
CCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRVLIVKTSSMGDVLHTLPALTDAQQVIPGIKFDWVVEEGFAQIPSWHAAVERVIPVAIR
CEEEEEECCCHHHHHHHHHHHCCHHHHHCCCCEEEEEHHHHHHCCHHHHHHHHHHHHHHH
RWRKAWFSAPIKAERKAFREALQAENYDAVIDAQGLVKSAALVTRLAHGVKHGMDWQTAR
HHHHHHHCCCHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHHHHHHHHHCCCCHHHHH
EPLASLFYNRKHHIAKQQHAVERTRELFAKSLGYSKPQTQGDYAIAQHFLTNLPTDAGKY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCE
AVFLHATTRDDKHWPETHWRELIGLLADSGIRIKLPWGAPHEEERAKRLAEGFDYVDVLP
EEEEEEECCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHCCCHHHHHH
KMSLEGVARVLAGAKFVVSVDTGLSHLTAALDRPNITVYGPTDPGLIGGYGKNQVVCRAP
CCCHHHHHHHHCCCEEEEEECCCHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCEEEECC
DKDLAYLTAETVFNKINS
CCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8478319; 8041620; 9278503; 1624462 [H]