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The map label for this gene is frvX [H]

Identifier: 218551118

GI number: 218551118

Start: 3968233

End: 3969303

Strand: Direct

Name: frvX [H]

Synonym: EFER_3874

Alternate gene names: 218551118

Gene position: 3968233-3969303 (Clockwise)

Preceding gene: 218551117

Following gene: 218551119

Centisome position: 86.48

GC content: 52.47

Gene sequence:

>1071_bases
ATGAACATTGAGTTACTGCAACAGTTGTGCGAAGCCAGCGCCGTCAGCGGCGATGAACAGGAAGTTCGCGACATTCTGAT
AAACACGCTGGAACCCTGCGTGAATGAGATCACCTTCGATGGGCTGGGCAGCTTTGTTGCCCGTAAGGGGAATAAAGGGC
CGAAAGTTGCCGTTGTCGGGCATATGGATGAAGTCGGCTTTATGGTCACCCACATCGACGAGAGCGGTTTTCTGCGTTTC
ACCACCATTGGTGGCTGGTGGAATCAGTCGATGTTCAACCACCGGGTAACCATACGCACACACAAGGGAGTGAAAATCCC
TGGTGTGATTGGTTCCGTCGCGCCTCATGCGTTAACCGAAAAACAAAAGCAACAACCGCTGTCATTTGATGAGATGTTCA
TTGATATTGGCGCAAACAGTCGCGAAGAGGTGGAAAAGCGCGGCGTGGAAATTGGCGATTTTATTAGCCCTGAGGCCAAT
TTTGCCTGCTGGGGCGAAGATAAAGTGGTCAGCAAGGCGTTGGATAACCGCATCGGCTGCGCAATGATGGCCGAGCTACT
ACAGACAGTAAATAACCCCGAAATTACGCTTTATGGCGTTGGCAGTGTGGAAGAAGAAGTTGGGCTACGCGGGGCACAAA
CCTCGGCTGAACACATTAAACCGGATGTGGTGATCGTGCTGGATACCGCCGTCGCGGGCGATGTTCCGGGCATTGATAAC
ATTAAATACCCGCTGAAACTGGGCAACGGGCCGGGGCTGATGTTGTTTGACAAGCGCTACTTCCCCAACCAGAAACTGGT
AGCAGCGTTAAAAAGCTGTGCCACGCAGAATGATTTACCGCTGCAATTTTCCACTATGAAAACCGGTGCGACGGATGGCG
GGCGCTACAACGTGATGGGCGGCGGGCGTCCGGTTGTCGCGCTGTGTCTGCCAACGCGTTATCTGCACGCCAATAGCGGT
ATGATTTCAAAAGCCGATTACGATGCTCTGCTCACGTTGATACGGGATTTTCTGACCACCTTAACCGCGGAGAAAGTCAA
CGCGTTTAGCCAGTTCCGTCAGGTGGATTAA

Upstream 100 bases:

>100_bases
GTGCTGGCGATTGGTCTCGCGCTGAACATTTCATTCATTATCGTCCTGAAAGGATTGTGGTTACGCCGCAAAGCGAAAGC
CGCGCAACAGGAGCTTGTCC

Downstream 100 bases:

>100_bases
TGCTAAACGAACGCCAGTTAAAGATTGTCGATCTGCTGGAGCAACAGCCACGCACGCCTGGCGAGCTGGCGCAACAGACT
GGCGTTTCTGGCAGGACCAT

Product: fructose-specific phosphotransferase system protein FrvX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MNIELLQQLCEASAVSGDEQEVRDILINTLEPCVNEITFDGLGSFVARKGNKGPKVAVVGHMDEVGFMVTHIDESGFLRF
TTIGGWWNQSMFNHRVTIRTHKGVKIPGVIGSVAPHALTEKQKQQPLSFDEMFIDIGANSREEVEKRGVEIGDFISPEAN
FACWGEDKVVSKALDNRIGCAMMAELLQTVNNPEITLYGVGSVEEEVGLRGAQTSAEHIKPDVVIVLDTAVAGDVPGIDN
IKYPLKLGNGPGLMLFDKRYFPNQKLVAALKSCATQNDLPLQFSTMKTGATDGGRYNVMGGGRPVVALCLPTRYLHANSG
MISKADYDALLTLIRDFLTTLTAEKVNAFSQFRQVD

Sequences:

>Translated_356_residues
MNIELLQQLCEASAVSGDEQEVRDILINTLEPCVNEITFDGLGSFVARKGNKGPKVAVVGHMDEVGFMVTHIDESGFLRF
TTIGGWWNQSMFNHRVTIRTHKGVKIPGVIGSVAPHALTEKQKQQPLSFDEMFIDIGANSREEVEKRGVEIGDFISPEAN
FACWGEDKVVSKALDNRIGCAMMAELLQTVNNPEITLYGVGSVEEEVGLRGAQTSAEHIKPDVVIVLDTAVAGDVPGIDN
IKYPLKLGNGPGLMLFDKRYFPNQKLVAALKSCATQNDLPLQFSTMKTGATDGGRYNVMGGGRPVVALCLPTRYLHANSG
MISKADYDALLTLIRDFLTTLTAEKVNAFSQFRQVD
>Mature_356_residues
MNIELLQQLCEASAVSGDEQEVRDILINTLEPCVNEITFDGLGSFVARKGNKGPKVAVVGHMDEVGFMVTHIDESGFLRF
TTIGGWWNQSMFNHRVTIRTHKGVKIPGVIGSVAPHALTEKQKQQPLSFDEMFIDIGANSREEVEKRGVEIGDFISPEAN
FACWGEDKVVSKALDNRIGCAMMAELLQTVNNPEITLYGVGSVEEEVGLRGAQTSAEHIKPDVVIVLDTAVAGDVPGIDN
IKYPLKLGNGPGLMLFDKRYFPNQKLVAALKSCATQNDLPLQFSTMKTGATDGGRYNVMGGGRPVVALCLPTRYLHANSG
MISKADYDALLTLIRDFLTTLTAEKVNAFSQFRQVD

Specific function: Unknown

COG id: COG1363

COG function: function code G; Cellulase M and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M42 family [H]

Homologues:

Organism=Escherichia coli, GI1790332, Length=356, Percent_Identity=97.752808988764, Blast_Score=721, Evalue=0.0,
Organism=Escherichia coli, GI1788727, Length=360, Percent_Identity=34.7222222222222, Blast_Score=197, Evalue=7e-52,
Organism=Escherichia coli, GI87082417, Length=343, Percent_Identity=29.7376093294461, Blast_Score=155, Evalue=3e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008007 [H]

Pfam domain/function: PF05343 Peptidase_M42 [H]

EC number: NA

Molecular weight: Translated: 38850; Mature: 38850

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIELLQQLCEASAVSGDEQEVRDILINTLEPCVNEITFDGLGSFVARKGNKGPKVAVVG
CCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
HMDEVGFMVTHIDESGFLRFTTIGGWWNQSMFNHRVTIRTHKGVKIPGVIGSVAPHALTE
CCCCCCEEEEEECCCCCEEEEEECCCHHHHHHCCEEEEEECCCEECCCHHHHCCCHHHHH
KQKQQPLSFDEMFIDIGANSREEVEKRGVEIGDFISPEANFACWGEDKVVSKALDNRIGC
HHHHCCCCHHHEEEECCCCCHHHHHHCCCCCCCCCCCCCCEEECCCHHHHHHHHHCCCCH
AMMAELLQTVNNPEITLYGVGSVEEEVGLRGAQTSAEHIKPDVVIVLDTAVAGDVPGIDN
HHHHHHHHHCCCCCEEEEECCCCHHHHCCCCCCCCHHHCCCCEEEEEECHHCCCCCCCCC
IKYPLKLGNGPGLMLFDKRYFPNQKLVAALKSCATQNDLPLQFSTMKTGATDGGRYNVMG
CEEEEEECCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCEEEECC
GGRPVVALCLPTRYLHANSGMISKADYDALLTLIRDFLTTLTAEKVNAFSQFRQVD
CCCCEEEEEECCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNIELLQQLCEASAVSGDEQEVRDILINTLEPCVNEITFDGLGSFVARKGNKGPKVAVVG
CCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
HMDEVGFMVTHIDESGFLRFTTIGGWWNQSMFNHRVTIRTHKGVKIPGVIGSVAPHALTE
CCCCCCEEEEEECCCCCEEEEEECCCHHHHHHCCEEEEEECCCEECCCHHHHCCCHHHHH
KQKQQPLSFDEMFIDIGANSREEVEKRGVEIGDFISPEANFACWGEDKVVSKALDNRIGC
HHHHCCCCHHHEEEECCCCCHHHHHHCCCCCCCCCCCCCCEEECCCHHHHHHHHHCCCCH
AMMAELLQTVNNPEITLYGVGSVEEEVGLRGAQTSAEHIKPDVVIVLDTAVAGDVPGIDN
HHHHHHHHHCCCCCEEEEECCCCHHHHCCCCCCCCHHHCCCCEEEEEECHHCCCCCCCCC
IKYPLKLGNGPGLMLFDKRYFPNQKLVAALKSCATQNDLPLQFSTMKTGATDGGRYNVMG
CEEEEEECCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCEEEECC
GGRPVVALCLPTRYLHANSGMISKADYDALLTLIRDFLTTLTAEKVNAFSQFRQVD
CCCCEEEEEECCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8346018; 9278503; 8019415 [H]