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The map label for this gene is ybhD [H]

Identifier: 218550936

GI number: 218550936

Start: 3748970

End: 3749938

Strand: Reverse

Name: ybhD [H]

Synonym: EFER_3662

Alternate gene names: 218550936

Gene position: 3749938-3748970 (Counterclockwise)

Preceding gene: 218550945

Following gene: 218550935

Centisome position: 81.72

GC content: 44.79

Gene sequence:

>969_bases
ATGAAAAGTGAACTTTTAGGTACAAAAGCTTTTGTGACTATTGCTGATTTAGGCTGTTTTACCAGGGCTGCGGATGAACT
TAATTTATCGCAACCCGCACTGACTCGCCGTGTGAAAAAACTGGAAGAAAGCCTGAAAGTGACTTTGTTTGAACGGACGA
CACGCAAAGTCACACTGACCAGTGCAGGTAAAGCTCTTTTACCTCATGCCCGGGCACTGTTAGGTTATATGGATGATGCC
ATTCTTAGTGTTCAGGAACTGGCGGTACATCAAAAAGGCGTTATTAAGTTATCCTGTATACCGACCGCAACATTTTATTT
CTTACCGCAAATATTAAAGAAGTTTAATACACTTTACCCGAATATCCGCGTCCATGTTCATGAACAGGCAACTGTCGATT
GCCTTAATTCTGTATTAAGTAGCGAAACAGATTTCGGTATTAATATGAATCGTGTTGTTCATCCACAAATTAATTTTACG
CCATTAATTGATGAACCTTATATTTTACTTTGTCGTCGCGACCACCCTTTAGCCAACAATAAACTGGTTGAGTGGCGGGA
CCTGGCGGCACATCGGCTGATAGGTGTCCGGCGTATCAGTGGCAACCGAATGTTGATTGAACAAGAAATTTCCCGGACGG
TCGGTACGCTGGAATGGTTTTATGAAGTGCGGCATTACTCGACAGCAATTGGCCTGGTGGAAGCCGGGCTGGGTATTGCT
GCGCTACCGTGCCTGGCGATGTCGCAAAACAATAGCCATAATTTAATCACCATTCCACTGGTAGAGCCGGTAATACGCAG
AAGTATTGGCCTGATTGCGAGGAATGATATCCCGCTGTCTCCCGCCGCTGAGCGACTGGTCAATTTATTGCAAGAGACAT
GGCTGGAACAAAATGCGCAGGAGCGGCACCGGGGAGTAACTCAATTTCTTCCATTTAATTTCACCCACCTTTCAGAGAAT
AAGGATTAA

Upstream 100 bases:

>100_bases
AATTTTTTGTGCACATACGCGCAAAATTATTATTGTAAAGTCACCAGGTGTGAGTATCTTTTAACGAGAATGTACCGACC
TTTAACTATGGAAAGCAGAG

Downstream 100 bases:

>100_bases
TCATGTCATCACACTCTGCGCTGCGATTTGCCATTAACTTAGGTAATGCCATGCTGGCCGGGCAATCGTCAGGTGGAGAA
TTACATGGGTTTACAGTTGA

Product: HTH-type transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MKSELLGTKAFVTIADLGCFTRAADELNLSQPALTRRVKKLEESLKVTLFERTTRKVTLTSAGKALLPHARALLGYMDDA
ILSVQELAVHQKGVIKLSCIPTATFYFLPQILKKFNTLYPNIRVHVHEQATVDCLNSVLSSETDFGINMNRVVHPQINFT
PLIDEPYILLCRRDHPLANNKLVEWRDLAAHRLIGVRRISGNRMLIEQEISRTVGTLEWFYEVRHYSTAIGLVEAGLGIA
ALPCLAMSQNNSHNLITIPLVEPVIRRSIGLIARNDIPLSPAAERLVNLLQETWLEQNAQERHRGVTQFLPFNFTHLSEN
KD

Sequences:

>Translated_322_residues
MKSELLGTKAFVTIADLGCFTRAADELNLSQPALTRRVKKLEESLKVTLFERTTRKVTLTSAGKALLPHARALLGYMDDA
ILSVQELAVHQKGVIKLSCIPTATFYFLPQILKKFNTLYPNIRVHVHEQATVDCLNSVLSSETDFGINMNRVVHPQINFT
PLIDEPYILLCRRDHPLANNKLVEWRDLAAHRLIGVRRISGNRMLIEQEISRTVGTLEWFYEVRHYSTAIGLVEAGLGIA
ALPCLAMSQNNSHNLITIPLVEPVIRRSIGLIARNDIPLSPAAERLVNLLQETWLEQNAQERHRGVTQFLPFNFTHLSEN
KD
>Mature_322_residues
MKSELLGTKAFVTIADLGCFTRAADELNLSQPALTRRVKKLEESLKVTLFERTTRKVTLTSAGKALLPHARALLGYMDDA
ILSVQELAVHQKGVIKLSCIPTATFYFLPQILKKFNTLYPNIRVHVHEQATVDCLNSVLSSETDFGINMNRVVHPQINFT
PLIDEPYILLCRRDHPLANNKLVEWRDLAAHRLIGVRRISGNRMLIEQEISRTVGTLEWFYEVRHYSTAIGLVEAGLGIA
ALPCLAMSQNNSHNLITIPLVEPVIRRSIGLIARNDIPLSPAAERLVNLLQETWLEQNAQERHRGVTQFLPFNFTHLSEN
KD

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693105, Length=314, Percent_Identity=55.7324840764331, Blast_Score=361, Evalue=1e-101,
Organism=Escherichia coli, GI1788748, Length=292, Percent_Identity=30.1369863013699, Blast_Score=140, Evalue=8e-35,
Organism=Escherichia coli, GI1790399, Length=289, Percent_Identity=30.7958477508651, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI157672245, Length=279, Percent_Identity=27.2401433691756, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1787879, Length=252, Percent_Identity=29.3650793650794, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1788887, Length=301, Percent_Identity=27.906976744186, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1787601, Length=289, Percent_Identity=24.9134948096886, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788297, Length=236, Percent_Identity=27.9661016949153, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1786713, Length=266, Percent_Identity=28.9473684210526, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI87081904, Length=184, Percent_Identity=29.8913043478261, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1789204, Length=273, Percent_Identity=23.8095238095238, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI2367136, Length=262, Percent_Identity=26.3358778625954, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1787530, Length=241, Percent_Identity=24.4813278008299, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI1788481, Length=283, Percent_Identity=24.3816254416961, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1787589, Length=150, Percent_Identity=32.6666666666667, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1786401, Length=185, Percent_Identity=25.9459459459459, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787128, Length=205, Percent_Identity=28.2926829268293, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1789173, Length=175, Percent_Identity=29.1428571428571, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI87082132, Length=287, Percent_Identity=23.3449477351916, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1788296, Length=239, Percent_Identity=25.1046025104602, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790208, Length=144, Percent_Identity=29.1666666666667, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1790262, Length=235, Percent_Identity=23.4042553191489, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1787806, Length=255, Percent_Identity=23.921568627451, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789506, Length=277, Percent_Identity=21.2996389891697, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 36330; Mature: 36330

Theoretical pI: Translated: 8.73; Mature: 8.73

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSELLGTKAFVTIADLGCFTRAADELNLSQPALTRRVKKLEESLKVTLFERTTRKVTLT
CCCCCCCCHHHEEHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEEEEEECCCCEEEEE
SAGKALLPHARALLGYMDDAILSVQELAVHQKGVIKLSCIPTATFYFLPQILKKFNTLYP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHCC
NIRVHVHEQATVDCLNSVLSSETDFGINMNRVVHPQINFTPLIDEPYILLCRRDHPLANN
CEEEEEECHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCEEECCCCEEEEEECCCCCCCC
KLVEWRDLAAHRLIGVRRISGNRMLIEQEISRTVGTLEWFYEVRHYSTAIGLVEAGLGIA
CCHHHHHHHHHHHHHEEEECCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
ALPCLAMSQNNSHNLITIPLVEPVIRRSIGLIARNDIPLSPAAERLVNLLQETWLEQNAQ
HHHHHHCCCCCCCCEEEEHHHHHHHHHHHCCEECCCCCCCHHHHHHHHHHHHHHHHCCHH
ERHRGVTQFLPFNFTHLSENKD
HHHCCHHHHCCCCEEECCCCCC
>Mature Secondary Structure
MKSELLGTKAFVTIADLGCFTRAADELNLSQPALTRRVKKLEESLKVTLFERTTRKVTLT
CCCCCCCCHHHEEHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEEEEEECCCCEEEEE
SAGKALLPHARALLGYMDDAILSVQELAVHQKGVIKLSCIPTATFYFLPQILKKFNTLYP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHCC
NIRVHVHEQATVDCLNSVLSSETDFGINMNRVVHPQINFTPLIDEPYILLCRRDHPLANN
CEEEEEECHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCEEECCCCEEEEEECCCCCCCC
KLVEWRDLAAHRLIGVRRISGNRMLIEQEISRTVGTLEWFYEVRHYSTAIGLVEAGLGIA
CCHHHHHHHHHHHHHEEEECCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
ALPCLAMSQNNSHNLITIPLVEPVIRRSIGLIARNDIPLSPAAERLVNLLQETWLEQNAQ
HHHHHHCCCCCCCCEEEEHHHHHHHHHHHCCEECCCCCCCHHHHHHHHHHHHHHHHCCHH
ERHRGVTQFLPFNFTHLSENKD
HHHCCHHHHCCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]