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The map label for this gene is selA [H]

Identifier: 218550869

GI number: 218550869

Start: 3671054

End: 3672445

Strand: Reverse

Name: selA [H]

Synonym: EFER_3585

Alternate gene names: 218550869

Gene position: 3672445-3671054 (Counterclockwise)

Preceding gene: 218550870

Following gene: 218550868

Centisome position: 80.03

GC content: 53.74

Gene sequence:

>1392_bases
ATGACTACCGAAACGCGTTCTTTATTTAGCCAGCTTCCTGCTATCGATCGTCTGTTGCGTGATAGTGCATTTCTCACTTT
GCGTGAAACTTACGGCCATACCCGAGTTGTTGACCTGCTACGTCAAATGGTTGACGAAGCGCGGGAGATGATTCGTGCAA
CCCAGGCCTTGCCCGCCTGGTGCGATAACTGGGCGTGTGAGGCAGATGCTCGCTTACAAAAAGAGGCGCAAAGCGCGTTA
CGTCCGGTAATTAACCTTACGGGCACGGTATTACATACCAATCTGGGAAGGGCGTTACAGGCAGAAGAGGCGGTAGCGGC
CGTTTCTCAGGCGATGCGCTCGCCAGTGACGCTGGAATATGACCTGGATGGTGCCGGTCGTGGGCATCGTGATCGCGCTC
TGGCGGAGTTACTTTGCCGCATTACGGGCGCGGAAGATGCCTGTATCGTCAATAACAATGCTGCTGCAGTGCTGTTGATG
TTGGCAGCAACTGCCAGCGGTAAAGAAGTGGTAGTTTCACGTGGGGAGTTGGTGGAGATTGGCGGTGCGTTTCGCATTCC
CGATGTGATGCGTCAGGCAGGATGCGCATTACATGAAGTGGGTACCACCAACCGCACCCATGCAAAGGATTATCGACAGG
CCGTAAATGAAAATACGGCATTGTTGATGAAAGTTCACACCAGTAATTACAGCATTGAAGGTTTCACCAAAGCAGTGGAT
GAAGCAGAGTTGGTGAGTATTGGTAAAGAGCTTGATATCCCGGTGGTCACGGATTTGGGTAGCGGTTCGCTGGTTGATCT
CAGCCAGTACGGCTTGCCAAAAGAGCCGATGCCACAGGAGCTTATCGCCGCAGGCGTGAGCCTGGTAAGTTTCTCTGGCG
ACAAGTTACTCGGCGGGCCGCAGGCGGGGATTATCGTCGGGAAAAAAGAGATGATTGCCCGCCTGCAAAGCCATCCGCTG
AAACGAGCGCTACGGGCAGATAAAATGACACTCGCCGCGCTGGAAGCCACTCTGCGTCTGTATTTGCATCCAGAAGCGCT
TAGCGAAAAATTACCGACATTACGTTTACTGACTCGTCAGCAAGAGAAGATTCAGGTACAAGGGCAGCGGTTACTGGCAC
CTTTACTTGCACATTATGGCGAGGAATTTGCGGTTGCGGTAATGCCGTGTCAGTCGCAAATTGGTAGCGGTTCGCTGCCT
GTTGATCGCCTGCCCAGTGCGGCATTAACGTTTACCCCACATGACGGACGCGGAAGCCGCCTGGAGACTCTGGCTGCCCG
TTGGCGCGAATTGCCCGTGCCGGTTATCGGACGGATTTACGATGGCCGCCTGTGGTTGGATTTGCGCTGCCTCGAAGATG
AGACCCGGTTTTTGGAGATGTTGCTGAAATGA

Upstream 100 bases:

>100_bases
TGATGCGTAATATGTCCGCCTGAACAATCTCACGTTACAATCCCCTTCATGTCGCAATCCCTCTCCGTTGGGGAGAGGGC
ACCAACTGCCGGGCCTCGTC

Downstream 100 bases:

>100_bases
TTATTGCTACCGCCGGACACGTAGACCACGGTAAAACCACGCTATTACAGGCAATTACGGGAGTTAACGCCGACCGCCTG
CCAGAAGAAAAGAAGCGTGG

Product: selenocysteine synthase

Products: NA

Alternate protein names: Selenocysteine synthase; Sec synthase; Selenocysteinyl-tRNA(Sec) synthase [H]

Number of amino acids: Translated: 463; Mature: 462

Protein sequence:

>463_residues
MTTETRSLFSQLPAIDRLLRDSAFLTLRETYGHTRVVDLLRQMVDEAREMIRATQALPAWCDNWACEADARLQKEAQSAL
RPVINLTGTVLHTNLGRALQAEEAVAAVSQAMRSPVTLEYDLDGAGRGHRDRALAELLCRITGAEDACIVNNNAAAVLLM
LAATASGKEVVVSRGELVEIGGAFRIPDVMRQAGCALHEVGTTNRTHAKDYRQAVNENTALLMKVHTSNYSIEGFTKAVD
EAELVSIGKELDIPVVTDLGSGSLVDLSQYGLPKEPMPQELIAAGVSLVSFSGDKLLGGPQAGIIVGKKEMIARLQSHPL
KRALRADKMTLAALEATLRLYLHPEALSEKLPTLRLLTRQQEKIQVQGQRLLAPLLAHYGEEFAVAVMPCQSQIGSGSLP
VDRLPSAALTFTPHDGRGSRLETLAARWRELPVPVIGRIYDGRLWLDLRCLEDETRFLEMLLK

Sequences:

>Translated_463_residues
MTTETRSLFSQLPAIDRLLRDSAFLTLRETYGHTRVVDLLRQMVDEAREMIRATQALPAWCDNWACEADARLQKEAQSAL
RPVINLTGTVLHTNLGRALQAEEAVAAVSQAMRSPVTLEYDLDGAGRGHRDRALAELLCRITGAEDACIVNNNAAAVLLM
LAATASGKEVVVSRGELVEIGGAFRIPDVMRQAGCALHEVGTTNRTHAKDYRQAVNENTALLMKVHTSNYSIEGFTKAVD
EAELVSIGKELDIPVVTDLGSGSLVDLSQYGLPKEPMPQELIAAGVSLVSFSGDKLLGGPQAGIIVGKKEMIARLQSHPL
KRALRADKMTLAALEATLRLYLHPEALSEKLPTLRLLTRQQEKIQVQGQRLLAPLLAHYGEEFAVAVMPCQSQIGSGSLP
VDRLPSAALTFTPHDGRGSRLETLAARWRELPVPVIGRIYDGRLWLDLRCLEDETRFLEMLLK
>Mature_462_residues
TTETRSLFSQLPAIDRLLRDSAFLTLRETYGHTRVVDLLRQMVDEAREMIRATQALPAWCDNWACEADARLQKEAQSALR
PVINLTGTVLHTNLGRALQAEEAVAAVSQAMRSPVTLEYDLDGAGRGHRDRALAELLCRITGAEDACIVNNNAAAVLLML
AATASGKEVVVSRGELVEIGGAFRIPDVMRQAGCALHEVGTTNRTHAKDYRQAVNENTALLMKVHTSNYSIEGFTKAVDE
AELVSIGKELDIPVVTDLGSGSLVDLSQYGLPKEPMPQELIAAGVSLVSFSGDKLLGGPQAGIIVGKKEMIARLQSHPLK
RALRADKMTLAALEATLRLYLHPEALSEKLPTLRLLTRQQEKIQVQGQRLLAPLLAHYGEEFAVAVMPCQSQIGSGSLPV
DRLPSAALTFTPHDGRGSRLETLAARWRELPVPVIGRIYDGRLWLDLRCLEDETRFLEMLLK

Specific function: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis [H]

COG id: COG1921

COG function: function code E; Selenocysteine synthase [seryl-tRNASer selenium transferase]

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the selA family [H]

Homologues:

Organism=Escherichia coli, GI2367248, Length=463, Percent_Identity=91.5766738660907, Blast_Score=827, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR018319
- InterPro:   IPR004534 [H]

Pfam domain/function: PF03841 SelA [H]

EC number: =2.9.1.1 [H]

Molecular weight: Translated: 50674; Mature: 50543

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTETRSLFSQLPAIDRLLRDSAFLTLRETYGHTRVVDLLRQMVDEAREMIRATQALPAW
CCCHHHHHHHHCHHHHHHHHHHHHEEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCHHH
CDNWACEADARLQKEAQSALRPVINLTGTVLHTNLGRALQAEEAVAAVSQAMRSPVTLEY
HCCCCCCHHHHHHHHHHHHHHHHHHCCHHHEECCCCHHHHHHHHHHHHHHHHCCCCEEEE
DLDGAGRGHRDRALAELLCRITGAEDACIVNNNAAAVLLMLAATASGKEVVVSRGELVEI
ECCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHCCCCCEEEEECCCEEEE
GGAFRIPDVMRQAGCALHEVGTTNRTHAKDYRQAVNENTALLMKVHTSNYSIEGFTKAVD
CCCCCCHHHHHHCCCHHHHCCCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHC
EAELVSIGKELDIPVVTDLGSGSLVDLSQYGLPKEPMPQELIAAGVSLVSFSGDKLLGGP
HHHHHHCCCCCCCCEEEECCCCCEEEHHHCCCCCCCCCHHHHHCCHHHEEECCCCCCCCC
QAGIIVGKKEMIARLQSHPLKRALRADKMTLAALEATLRLYLHPEALSEKLPTLRLLTRQ
CCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECHHHHHHCCCHHHHHHHH
QEKIQVQGQRLLAPLLAHYGEEFAVAVMPCQSQIGSGSLPVDRLPSAALTFTPHDGRGSR
HHHHHHHHHHHHHHHHHHCCCCEEEEEEECHHCCCCCCCCHHHCCCCEEEECCCCCCCCH
LETLAARWRELPVPVIGRIYDGRLWLDLRCLEDETRFLEMLLK
HHHHHHHHHHCCCCHHCEEECCEEEEEEEECCHHHHHHHHHHC
>Mature Secondary Structure 
TTETRSLFSQLPAIDRLLRDSAFLTLRETYGHTRVVDLLRQMVDEAREMIRATQALPAW
CCHHHHHHHHCHHHHHHHHHHHHEEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCHHH
CDNWACEADARLQKEAQSALRPVINLTGTVLHTNLGRALQAEEAVAAVSQAMRSPVTLEY
HCCCCCCHHHHHHHHHHHHHHHHHHCCHHHEECCCCHHHHHHHHHHHHHHHHCCCCEEEE
DLDGAGRGHRDRALAELLCRITGAEDACIVNNNAAAVLLMLAATASGKEVVVSRGELVEI
ECCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHCCCCCEEEEECCCEEEE
GGAFRIPDVMRQAGCALHEVGTTNRTHAKDYRQAVNENTALLMKVHTSNYSIEGFTKAVD
CCCCCCHHHHHHCCCHHHHCCCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHC
EAELVSIGKELDIPVVTDLGSGSLVDLSQYGLPKEPMPQELIAAGVSLVSFSGDKLLGGP
HHHHHHCCCCCCCCEEEECCCCCEEEHHHCCCCCCCCCHHHHHCCHHHEEECCCCCCCCC
QAGIIVGKKEMIARLQSHPLKRALRADKMTLAALEATLRLYLHPEALSEKLPTLRLLTRQ
CCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECHHHHHHCCCHHHHHHHH
QEKIQVQGQRLLAPLLAHYGEEFAVAVMPCQSQIGSGSLPVDRLPSAALTFTPHDGRGSR
HHHHHHHHHHHHHHHHHHCCCCEEEEEEECHHCCCCCCCCHHHCCCCEEEECCCCCCCCH
LETLAARWRELPVPVIGRIYDGRLWLDLRCLEDETRFLEMLLK
HHHHHHHHHHCCCCHHCEEECCEEEEEEEECCHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA