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The map label for this gene is yiaN [H]

Identifier: 218550860

GI number: 218550860

Start: 3660106

End: 3661383

Strand: Direct

Name: yiaN [H]

Synonym: EFER_3576

Alternate gene names: 218550860

Gene position: 3660106-3661383 (Clockwise)

Preceding gene: 218550859

Following gene: 218550861

Centisome position: 79.76

GC content: 50.08

Gene sequence:

>1278_bases
ATGGCTGTGCTGATTTTTCTGGGCTGCCTGTTGGGTGGCATTGCTATCGGTTTGCCTATTGCCTGGTCGCTACTGTTGTG
CGGGGCGGCGCTTATGTTCTGGCTGGATATGTTTGATGTCCAGATCATGGCGCAAACGCTGGTAAACGGTGCTGACAGCT
TCTCCCTGCTGGCGATTCCGTTCTTTGTACTGGCGGGTGAAATCATGAATGCGGGCGGCTTATCAAAACGCATTGTTGAC
CTGCCGATGAAACTGGTGGGGCATAAACCAGGCGGGCTGGGCTACGTCGGCGTGCTGGCGGCTATGATTATGGCGAGCCT
TTCTGGTTCTGCTGTTGCTGATACCGCCGCCGTTGCCGCGCTATTAGTGCCGATGATGCGCAGCGCTAACTACCCGGTCA
ACCGGGCTGCGGGGCTGATTGCCTCTGGCGGCATTATCGCGCCAATTATTCCCCCTTCCATTCCGTTTATTATCTTCGGT
GTTTCCAGCGGATTATCCATCAGTAAGTTGTTTATGGCGGGTATTGCCCCAGGCATTATGATGGGCGCAACGCTGATGCT
CACCTGGTGGTGGCAGGCCAGTCGTCTTAATTTACCCCGTCAGCAAAAAGCAACGAAACGAGAAATCTGGCAATCTTTTG
TTTCCGGTATCTGGGCGCTATTTCTTCCGGTCATTATTATTGGCGGCTTTCGCTCCGGTCTGTTTACCCCTACCGAAGCC
GGGGCCGTTGCTGCTTTCTATGCGTTGTTTGTCGCCACAGTTATTTACCGTGAAATGACCTTCGCCACACTTTGGCATGT
ACTCATTGGCGCGGCGAAAACGACCTCAGTGGTGATGTTTCTGGTGGCCTCGGCACAAGTTTCTGCCTGGCTGATTACCA
TTGCTGAATTGCCGATGATGGTTTCTGATTTACTGCAACCGTTGGTCGATTCACCGCGTCTGCTGTTTATCGTCATTATG
GTGGCTATCCTGATTGTCGGCATGGTCATGGATTTAACGCCGACGGTGTTAATTCTTACCCCGGTATTAATGCCTTTAGT
TAAAGAGGCAGGAATCGATCCGATTTATTTCGGTGTCATGTTTATCATCAACTGCTCAATCGGCTTAATTACACCGCCTA
TCGGTAATGTGCTTAACGTTATTTCAGGGGTGGCTAAACTCAAATTCGATGATGCAGTCAGAGGCGTTTTCCCTTACGTC
CTGGTTTTATATTCCTTATTAGCCTTATTTGTTTTTATTCCCGATCTCATCATCCTCCCGTTGAAATGGATTAATTAA

Upstream 100 bases:

>100_bases
TGCCCACCAGCCTCGTTATCGCATTCTTTGAGCTGCGCCTTTTATATCAACTCATCACGCGTAGCAATTCCCTAACGCCG
CCACCGCAAGGAGCTTAATC

Downstream 100 bases:

>100_bases
AAGGAAAATATTATGAAATTACGTTCTGTAACCTACGCATTATTCATTGCTGGCCTGGCTGCATTCAGTACATCTTCACT
GGCGACACAATCATTACGTT

Product: transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 425; Mature: 424

Protein sequence:

>425_residues
MAVLIFLGCLLGGIAIGLPIAWSLLLCGAALMFWLDMFDVQIMAQTLVNGADSFSLLAIPFFVLAGEIMNAGGLSKRIVD
LPMKLVGHKPGGLGYVGVLAAMIMASLSGSAVADTAAVAALLVPMMRSANYPVNRAAGLIASGGIIAPIIPPSIPFIIFG
VSSGLSISKLFMAGIAPGIMMGATLMLTWWWQASRLNLPRQQKATKREIWQSFVSGIWALFLPVIIIGGFRSGLFTPTEA
GAVAAFYALFVATVIYREMTFATLWHVLIGAAKTTSVVMFLVASAQVSAWLITIAELPMMVSDLLQPLVDSPRLLFIVIM
VAILIVGMVMDLTPTVLILTPVLMPLVKEAGIDPIYFGVMFIINCSIGLITPPIGNVLNVISGVAKLKFDDAVRGVFPYV
LVLYSLLALFVFIPDLIILPLKWIN

Sequences:

>Translated_425_residues
MAVLIFLGCLLGGIAIGLPIAWSLLLCGAALMFWLDMFDVQIMAQTLVNGADSFSLLAIPFFVLAGEIMNAGGLSKRIVD
LPMKLVGHKPGGLGYVGVLAAMIMASLSGSAVADTAAVAALLVPMMRSANYPVNRAAGLIASGGIIAPIIPPSIPFIIFG
VSSGLSISKLFMAGIAPGIMMGATLMLTWWWQASRLNLPRQQKATKREIWQSFVSGIWALFLPVIIIGGFRSGLFTPTEA
GAVAAFYALFVATVIYREMTFATLWHVLIGAAKTTSVVMFLVASAQVSAWLITIAELPMMVSDLLQPLVDSPRLLFIVIM
VAILIVGMVMDLTPTVLILTPVLMPLVKEAGIDPIYFGVMFIINCSIGLITPPIGNVLNVISGVAKLKFDDAVRGVFPYV
LVLYSLLALFVFIPDLIILPLKWIN
>Mature_424_residues
AVLIFLGCLLGGIAIGLPIAWSLLLCGAALMFWLDMFDVQIMAQTLVNGADSFSLLAIPFFVLAGEIMNAGGLSKRIVDL
PMKLVGHKPGGLGYVGVLAAMIMASLSGSAVADTAAVAALLVPMMRSANYPVNRAAGLIASGGIIAPIIPPSIPFIIFGV
SSGLSISKLFMAGIAPGIMMGATLMLTWWWQASRLNLPRQQKATKREIWQSFVSGIWALFLPVIIIGGFRSGLFTPTEAG
AVAAFYALFVATVIYREMTFATLWHVLIGAAKTTSVVMFLVASAQVSAWLITIAELPMMVSDLLQPLVDSPRLLFIVIMV
AILIVGMVMDLTPTVLILTPVLMPLVKEAGIDPIYFGVMFIINCSIGLITPPIGNVLNVISGVAKLKFDDAVRGVFPYVL
VLYSLLALFVFIPDLIILPLKWIN

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system yiaMNO involved in the uptake of 2,3- diketo-L-gulonate [H]

COG id: COG1593

COG function: function code G; TRAP-type C4-dicarboxylate transport system, large permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=425, Percent_Identity=98.3529411764706, Blast_Score=813, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM [H]

EC number: NA

Molecular weight: Translated: 45369; Mature: 45238

Theoretical pI: Translated: 8.79; Mature: 8.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHCCC
>Mature Secondary Structure 
AVLIFLGCLLGGIAIGLPIAWSLLLCGAALMFWLDMFDVQIMAQTLVNGADSFSLLAIP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
FFVLAGEIMNAGGLSKRIVDLPMKLVGHKPGGLGYVGVLAAMIMASLSGSAVADTAAVAA
HHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHH
LLVPMMRSANYPVNRAAGLIASGGIIAPIIPPSIPFIIFGVSSGLSISKLFMAGIAPGIM
HHHHHHHCCCCCHHHHHHHHHCCCEEECCCCCCCCEEEEECCCCCHHHHHHHHHCCHHHH
MGATLMLTWWWQASRLNLPRQQKATKREIWQSFVSGIWALFLPVIIIGGFRSGLFTPTEA
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GAVAAFYALFVATVIYREMTFATLWHVLIGAAKTTSVVMFLVASAQVSAWLITIAELPMM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSDLLQPLVDSPRLLFIVIMVAILIVGMVMDLTPTVLILTPVLMPLVKEAGIDPIYFGVM
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCHHHHHHH
FIINCSIGLITPPIGNVLNVISGVAKLKFDDAVRGVFPYVLVLYSLLALFVFIPDLIILP
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKWIN
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503 [H]