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The map label for this gene is ttuB [H]

Identifier: 218550837

GI number: 218550837

Start: 3635272

End: 3636552

Strand: Direct

Name: ttuB [H]

Synonym: EFER_3553

Alternate gene names: 218550837

Gene position: 3635272-3636552 (Clockwise)

Preceding gene: 218550836

Following gene: 218550838

Centisome position: 79.22

GC content: 50.51

Gene sequence:

>1281_bases
ATGAACAGCTCAACAAACGCAGCAAAACGTTGGTGGTACATCATGCCTATCGTGTTTATCACGTATAGCCTGGCGTACCT
TGATCGTGCGAACTTTAGTTTCGCATCCGCCGCTGGCATCAACGAAGACCTCGGTATTACTAAAGGGATTTCGTCGCTGC
TGGGGGCCCTTTTCTTCCTCGGTTACTTCTTTTTCCAGATCCCTGGAGCGGTATATGCAGAACGGCGTAGTGTCCGCAAA
CTGATTTTCGTCTGTCTAATCTTATGGGGCGGTTGTGCCTCGCTGACAGGGATGGTCAGCAACATTCCGGCACTGGCAGC
AATTCGCTTTATTCTCGGGGTGGTAGAAGCTGCGGTCATGCCTGCGATGCTGATATATATCAGTAACTGGTTTACCAAAT
CTGAACGCTCACGTGCCAATACCTTTCTGATCCTTGGAAATCCGGTAACAGTGCTGTGGATGTCGGTTGTCTCTGGCTAC
CTGATTCAGGCGTTTGGCTGGCGCGAAATGTTTATCATCGAAGGTGTGCCGGCCATCATCTGGGCCTTTTGTTGGTGGGT
GCTGGTAAAAGATAAACCTGCGCAGGCAGGCTGGCTTTCTGAATCAGAGAAAGCGGCGTTACAGGCACAGTTAGAGCAGG
AACAACAAGGTATCAAAGCCGTTCGTAACTATGGTGAAGCCTTCCGCTCCCGTAACGTCATCTTACTGTGTATGCAGTAT
TTTACCTGGAGCATCGGGGTATATGGGTTTGTGCTCTGGTTACCATCAATTATCCGTAGCGGTGGTGAAAACCTGGGTAT
GGTTGAAGTCGGCTGGCTCTCTTCTGTCCCCTATCTGGCAGCGACAGCGGCAATGATTATTGTCTCCTGGGCATCGGACA
AATTGCAAAATCGTAAGCTCTTTGTCTGGCCTTCACTGCTGATTGCCGCGATTGCCTTTATCGGCTCCTGGGCCGTGGGT
GCTAACAATTTCTGGCTTTCTTATACCTTACTGGTGATCGCAGGCGCTGCAATGTATGCCCCGTATGGTCCGTTCTTTGC
CATTATTCCAGAAATGCTGCCACGTAATGTTGCCGGTGGCGCAATGGCATTGATCAACAGTATGGGAGCGCTGGGCTCGT
TCCTCGGCTCATGGTTTGTTGGTTATCTCAATGGGGTAACCGGTAGCCCATCAGCATCATTCATTTTCATGGGGGTAGCG
CTTTTCGTTTCTGTATGGCTAACATTGATTGTTAAACCAGCAGCCAATCAACCGCTACCCGTTGGCGCGCGCCACGCTTA
A

Upstream 100 bases:

>100_bases
GAGTAATTCCCCTATAAAAATGAGTAACAAAACAATCTGATACGTACTCCTCTGTCCCTACCTACAGAGGCGCTCTAACC
TGAAGCATAGAGGCAGGCCT

Downstream 100 bases:

>100_bases
ATATTAATCACGGAGATTCGCATGAAGCCGTCCATTATTCTTTATAAAAAGTTACCTGACGTTTTACTGCAACGCCTTGA
GGAACACTTTACTGTAACGC

Product: carboxylate-containing product, possibly ketogluconate transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 426

Protein sequence:

>426_residues
MNSSTNAAKRWWYIMPIVFITYSLAYLDRANFSFASAAGINEDLGITKGISSLLGALFFLGYFFFQIPGAVYAERRSVRK
LIFVCLILWGGCASLTGMVSNIPALAAIRFILGVVEAAVMPAMLIYISNWFTKSERSRANTFLILGNPVTVLWMSVVSGY
LIQAFGWREMFIIEGVPAIIWAFCWWVLVKDKPAQAGWLSESEKAALQAQLEQEQQGIKAVRNYGEAFRSRNVILLCMQY
FTWSIGVYGFVLWLPSIIRSGGENLGMVEVGWLSSVPYLAATAAMIIVSWASDKLQNRKLFVWPSLLIAAIAFIGSWAVG
ANNFWLSYTLLVIAGAAMYAPYGPFFAIIPEMLPRNVAGGAMALINSMGALGSFLGSWFVGYLNGVTGSPSASFIFMGVA
LFVSVWLTLIVKPAANQPLPVGARHA

Sequences:

>Translated_426_residues
MNSSTNAAKRWWYIMPIVFITYSLAYLDRANFSFASAAGINEDLGITKGISSLLGALFFLGYFFFQIPGAVYAERRSVRK
LIFVCLILWGGCASLTGMVSNIPALAAIRFILGVVEAAVMPAMLIYISNWFTKSERSRANTFLILGNPVTVLWMSVVSGY
LIQAFGWREMFIIEGVPAIIWAFCWWVLVKDKPAQAGWLSESEKAALQAQLEQEQQGIKAVRNYGEAFRSRNVILLCMQY
FTWSIGVYGFVLWLPSIIRSGGENLGMVEVGWLSSVPYLAATAAMIIVSWASDKLQNRKLFVWPSLLIAAIAFIGSWAVG
ANNFWLSYTLLVIAGAAMYAPYGPFFAIIPEMLPRNVAGGAMALINSMGALGSFLGSWFVGYLNGVTGSPSASFIFMGVA
LFVSVWLTLIVKPAANQPLPVGARHA
>Mature_426_residues
MNSSTNAAKRWWYIMPIVFITYSLAYLDRANFSFASAAGINEDLGITKGISSLLGALFFLGYFFFQIPGAVYAERRSVRK
LIFVCLILWGGCASLTGMVSNIPALAAIRFILGVVEAAVMPAMLIYISNWFTKSERSRANTFLILGNPVTVLWMSVVSGY
LIQAFGWREMFIIEGVPAIIWAFCWWVLVKDKPAQAGWLSESEKAALQAQLEQEQQGIKAVRNYGEAFRSRNVILLCMQY
FTWSIGVYGFVLWLPSIIRSGGENLGMVEVGWLSSVPYLAATAAMIIVSWASDKLQNRKLFVWPSLLIAAIAFIGSWAVG
ANNFWLSYTLLVIAGAAMYAPYGPFFAIIPEMLPRNVAGGAMALINSMGALGSFLGSWFVGYLNGVTGSPSASFIFMGVA
LFVSVWLTLIVKPAANQPLPVGARHA

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI6912666, Length=277, Percent_Identity=25.2707581227437, Blast_Score=69, Evalue=8e-12,
Organism=Escherichia coli, GI87082071, Length=375, Percent_Identity=27.2, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI87082320, Length=403, Percent_Identity=24.8138957816377, Blast_Score=108, Evalue=8e-25,
Organism=Escherichia coli, GI2367379, Length=318, Percent_Identity=23.2704402515723, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI1789152, Length=452, Percent_Identity=23.2300884955752, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1789515, Length=438, Percent_Identity=23.2876712328767, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI2367193, Length=434, Percent_Identity=26.036866359447, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI87082404, Length=378, Percent_Identity=24.0740740740741, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI115533556, Length=270, Percent_Identity=25.9259259259259, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI115533554, Length=270, Percent_Identity=25.9259259259259, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17535049, Length=404, Percent_Identity=23.2673267326733, Blast_Score=71, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI86561091, Length=253, Percent_Identity=24.5059288537549, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25141318, Length=253, Percent_Identity=24.5059288537549, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17552542, Length=325, Percent_Identity=24.9230769230769, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI25141316, Length=253, Percent_Identity=24.5059288537549, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI32565916, Length=195, Percent_Identity=23.5897435897436, Blast_Score=68, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI25141341, Length=201, Percent_Identity=24.8756218905473, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI32565914, Length=195, Percent_Identity=23.5897435897436, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17560030, Length=278, Percent_Identity=20.5035971223022, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322612, Length=220, Percent_Identity=24.5454545454545, Blast_Score=78, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6322973, Length=130, Percent_Identity=29.2307692307692, Blast_Score=66, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6321698, Length=339, Percent_Identity=22.4188790560472, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI45550460, Length=399, Percent_Identity=24.3107769423559, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI28573708, Length=378, Percent_Identity=25.3968253968254, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI28573707, Length=378, Percent_Identity=25.3968253968254, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI20130135, Length=453, Percent_Identity=23.6203090507726, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24655271, Length=453, Percent_Identity=23.6203090507726, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24655255, Length=360, Percent_Identity=24.4444444444444, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24580790, Length=351, Percent_Identity=23.0769230769231, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24648416, Length=275, Percent_Identity=25.8181818181818, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21356189, Length=275, Percent_Identity=25.8181818181818, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24641682, Length=174, Percent_Identity=27.0114942528736, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI20130167, Length=284, Percent_Identity=24.6478873239437, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46706; Mature: 46706

Theoretical pI: Translated: 9.61; Mature: 9.61

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSSTNAAKRWWYIMPIVFITYSLAYLDRANFSFASAAGINEDLGITKGISSLLGALFFL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHH
GYFFFQIPGAVYAERRSVRKLIFVCLILWGGCASLTGMVSNIPALAAIRFILGVVEAAVM
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
PAMLIYISNWFTKSERSRANTFLILGNPVTVLWMSVVSGYLIQAFGWREMFIIEGVPAII
HHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHH
WAFCWWVLVKDKPAQAGWLSESEKAALQAQLEQEQQGIKAVRNYGEAFRSRNVILLCMQY
HHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
FTWSIGVYGFVLWLPSIIRSGGENLGMVEVGWLSSVPYLAATAAMIIVSWASDKLQNRKL
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCEE
FVWPSLLIAAIAFIGSWAVGANNFWLSYTLLVIAGAAMYAPYGPFFAIIPEMLPRNVAGG
EECHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCH
AMALINSMGALGSFLGSWFVGYLNGVTGSPSASFIFMGVALFVSVWLTLIVKPAANQPLP
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
VGARHA
CCCCCC
>Mature Secondary Structure
MNSSTNAAKRWWYIMPIVFITYSLAYLDRANFSFASAAGINEDLGITKGISSLLGALFFL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHH
GYFFFQIPGAVYAERRSVRKLIFVCLILWGGCASLTGMVSNIPALAAIRFILGVVEAAVM
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
PAMLIYISNWFTKSERSRANTFLILGNPVTVLWMSVVSGYLIQAFGWREMFIIEGVPAII
HHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHH
WAFCWWVLVKDKPAQAGWLSESEKAALQAQLEQEQQGIKAVRNYGEAFRSRNVILLCMQY
HHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
FTWSIGVYGFVLWLPSIIRSGGENLGMVEVGWLSSVPYLAATAAMIIVSWASDKLQNRKL
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCEE
FVWPSLLIAAIAFIGSWAVGANNFWLSYTLLVIAGAAMYAPYGPFFAIIPEMLPRNVAGG
EECHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCH
AMALINSMGALGSFLGSWFVGYLNGVTGSPSASFIFMGVALFVSVWLTLIVKPAANQPLP
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
VGARHA
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]