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The map label for this gene is siiCB [C]

Identifier: 218550771

GI number: 218550771

Start: 3556999

End: 3558402

Strand: Direct

Name: siiCB [C]

Synonym: EFER_3482

Alternate gene names: 218550771

Gene position: 3556999-3558402 (Clockwise)

Preceding gene: 218550770

Following gene: 218550772

Centisome position: 77.52

GC content: 57.05

Gene sequence:

>1404_bases
ATGGGAAAAATGGCCTGCGTCGCGGCATTAGTGGCATTGGCGCTCAGTTGCGGGCATCTCAATGCACAAGAACTACCGAT
CTCCTCTGAAACCCTCGCCGCAGACCAGATGCTGCCTTCTCTCGATGGCTCGGCGGCGCAATTACCGCTCAGCCCGGCAG
CACCAGGAACATTAATGCTTAATGAGGCGGTCGGTCGCGCGGTGAACTGGCATCCTTCAATCAGCGAAGCCGTCGGCAAA
TTGCTGTCGCAAAATGAACAGATTGAAGTGGCGAAAGCAAAATACTACCCACAGATTAGCGCCGGGGTGAACAACGGCTA
TAGCAATACCTATCTCGACCACGGCTACAGCCCCGCGCTGGTGTTGTCGATCTCCCAAATGCTCTATGACTTCGGCAAAG
TCGCAAGCCAGGTGCGCGCCGAAAGCGCAGGCGCTGCCGAAGAGCAGGCCAACGTGTTGTTGAGTATTGATAGCGTGGCG
CATGAAACGGCAAACGCCATTGTGCAGGTGCAGGCAGCGCAGCAGATGGTCGAAGCTGCGGAAGAACAACTGGTTGCACT
TAACGGTATCGGCAAACTGACCCGGCAGCGCAACGATGAAGGCGCTACGTCGATGTCTGACGTGGTGCAAACCGATGCAC
GAATCGAGGCGGCACGCTCGCAACTGGCACAGTATCAGGCCGATCTCGACAGCGCCAAAGCCTCGCTGATGAGTATGCTT
GGCTGGAACTCGCTCAACGCCATCAGCAATGATTTCCCCCACAAACTGGACGGTAGCTGTGAGCAAGCCAAACCCGACGA
TCGCTTAGTCCCTGCCGTGTTAGCGGCCTGGGCGCAGGCAAATGTGGCGCAGGCTAATCTCGATTACGCCAACGCACAAA
TGACGCCCACCATCTCGCTGGAACCGTCCGTTCAGCACTATCTCAACGACAAATACCCCAGCCACGATGTGCTCGATAAA
ACGCAATATACCGCAATGGTCAAAGTAGAGATGCCCATCTATCAGGGCGGCGGGCTGACCGCACGGCGCAATGCCGCCAG
CCACGCGGTGGAATCGGCACAATCGGCAATTCAGCGCACCCGTCTTGAGGTGCGGCGAAAACTGCTGGATTCACGTAGCC
AGTCAATGAGCCTCGCCAGCGCGTTACAAATTCTGCGCCGCCAGCAACAGCTCAGCGAACGCACGCGCGAATTGTATCAA
CAGCAATATCTCGACCTCGGTTCGCGCCCGTTGCTGGATGTACTCAACGCCGAGCAGGAGGTGTATCAGGCGCGTTTTGC
AGAACTGCAAATCCAGAGCCAGCTTCGGCAGCTGCAACTGAACTGCCTGTATAACACCGGCACGCTGCGTCAGGCATTTG
CCCTCAACAACCGCCGCATTCAGTCCGTGGAGATCCAGCCATGA

Upstream 100 bases:

>100_bases
CAACAAAATCACATTGTGACCTGACAAAAACGCGAAACAGCCCCGGAGGCGATGACCACCGGGGCAACGGTAGTTATTTT
GATTTTCAAAGGGATAGATT

Downstream 100 bases:

>100_bases
CCCGCACCGCGCCACCGTTTAACCAGACATGTGATGAACGCGTCCTCAGCCAGTGGGCGCGAGCCATCAGCCATACTGCC
AGCCATTACCGCATCGCCTG

Product: outer membrane export protein

Products: NA

Alternate protein names: Outer Membrane Efflux Protein; Outer Membrane Efflux SS; Outer Membrane Protein; Outer Membrane Transport Protein Type I Secretion; Type I Secretion Protein; Outer Membrane Efflux Protein Type I Secretion Protein; Transport System Outer Membrane Protein; TypeIsecretion System Outer Membrane Efflux Protein; HAS ABC Exporter Outer Membrane Component; Outer Membrane Export Protein; Type I Secretion Outer Membrane Protein; Type I Secretion Outer Membrane Protein lC Family; HAS ABC Exporter Outer Membrane Component Protein; RND Efflux Transporter

Number of amino acids: Translated: 467; Mature: 466

Protein sequence:

>467_residues
MGKMACVAALVALALSCGHLNAQELPISSETLAADQMLPSLDGSAAQLPLSPAAPGTLMLNEAVGRAVNWHPSISEAVGK
LLSQNEQIEVAKAKYYPQISAGVNNGYSNTYLDHGYSPALVLSISQMLYDFGKVASQVRAESAGAAEEQANVLLSIDSVA
HETANAIVQVQAAQQMVEAAEEQLVALNGIGKLTRQRNDEGATSMSDVVQTDARIEAARSQLAQYQADLDSAKASLMSML
GWNSLNAISNDFPHKLDGSCEQAKPDDRLVPAVLAAWAQANVAQANLDYANAQMTPTISLEPSVQHYLNDKYPSHDVLDK
TQYTAMVKVEMPIYQGGGLTARRNAASHAVESAQSAIQRTRLEVRRKLLDSRSQSMSLASALQILRRQQQLSERTRELYQ
QQYLDLGSRPLLDVLNAEQEVYQARFAELQIQSQLRQLQLNCLYNTGTLRQAFALNNRRIQSVEIQP

Sequences:

>Translated_467_residues
MGKMACVAALVALALSCGHLNAQELPISSETLAADQMLPSLDGSAAQLPLSPAAPGTLMLNEAVGRAVNWHPSISEAVGK
LLSQNEQIEVAKAKYYPQISAGVNNGYSNTYLDHGYSPALVLSISQMLYDFGKVASQVRAESAGAAEEQANVLLSIDSVA
HETANAIVQVQAAQQMVEAAEEQLVALNGIGKLTRQRNDEGATSMSDVVQTDARIEAARSQLAQYQADLDSAKASLMSML
GWNSLNAISNDFPHKLDGSCEQAKPDDRLVPAVLAAWAQANVAQANLDYANAQMTPTISLEPSVQHYLNDKYPSHDVLDK
TQYTAMVKVEMPIYQGGGLTARRNAASHAVESAQSAIQRTRLEVRRKLLDSRSQSMSLASALQILRRQQQLSERTRELYQ
QQYLDLGSRPLLDVLNAEQEVYQARFAELQIQSQLRQLQLNCLYNTGTLRQAFALNNRRIQSVEIQP
>Mature_466_residues
GKMACVAALVALALSCGHLNAQELPISSETLAADQMLPSLDGSAAQLPLSPAAPGTLMLNEAVGRAVNWHPSISEAVGKL
LSQNEQIEVAKAKYYPQISAGVNNGYSNTYLDHGYSPALVLSISQMLYDFGKVASQVRAESAGAAEEQANVLLSIDSVAH
ETANAIVQVQAAQQMVEAAEEQLVALNGIGKLTRQRNDEGATSMSDVVQTDARIEAARSQLAQYQADLDSAKASLMSMLG
WNSLNAISNDFPHKLDGSCEQAKPDDRLVPAVLAAWAQANVAQANLDYANAQMTPTISLEPSVQHYLNDKYPSHDVLDKT
QYTAMVKVEMPIYQGGGLTARRNAASHAVESAQSAIQRTRLEVRRKLLDSRSQSMSLASALQILRRQQQLSERTRELYQQ
QYLDLGSRPLLDVLNAEQEVYQARFAELQIQSQLRQLQLNCLYNTGTLRQAFALNNRRIQSVEIQP

Specific function: In Pathogenic Strains It Allows The Bacteria To Invade Brain Microvascular Endothelial Cells (Bmec) Thus Allowing It To Cross The Blood-Brain Barrier And Cause Neonatal Meningitis. [C]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Attached To The Outer Membrane By A Lipid Anchor [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 50863; Mature: 50732

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKMACVAALVALALSCGHLNAQELPISSETLAADQMLPSLDGSAAQLPLSPAAPGTLML
CCHHHHHHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEE
NEAVGRAVNWHPSISEAVGKLLSQNEQIEVAKAKYYPQISAGVNNGYSNTYLDHGYSPAL
HHHHCCCCCCCCCHHHHHHHHHCCCCCEEEHHHHCCCCHHCCCCCCCCCCCCCCCCCHHH
VLSISQMLYDFGKVASQVRAESAGAAEEQANVLLSIDSVAHETANAIVQVQAAQQMVEAA
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
EEQLVALNGIGKLTRQRNDEGATSMSDVVQTDARIEAARSQLAQYQADLDSAKASLMSML
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GWNSLNAISNDFPHKLDGSCEQAKPDDRLVPAVLAAWAQANVAQANLDYANAQMTPTISL
CCCHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHCCCCCCCCCCCEEEEC
EPSVQHYLNDKYPSHDVLDKTQYTAMVKVEMPIYQGGGLTARRNAASHAVESAQSAIQRT
CCHHHHHHCCCCCCCHHHCCCCCEEEEEEEECEECCCCCCCHHHHHHHHHHHHHHHHHHH
RLEVRRKLLDSRSQSMSLASALQILRRQQQLSERTRELYQQQYLDLGSRPLLDVLNAEQE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
VYQARFAELQIQSQLRQLQLNCLYNTGTLRQAFALNNRRIQSVEIQP
HHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHCCCCEEEEECCC
>Mature Secondary Structure 
GKMACVAALVALALSCGHLNAQELPISSETLAADQMLPSLDGSAAQLPLSPAAPGTLML
CHHHHHHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEE
NEAVGRAVNWHPSISEAVGKLLSQNEQIEVAKAKYYPQISAGVNNGYSNTYLDHGYSPAL
HHHHCCCCCCCCCHHHHHHHHHCCCCCEEEHHHHCCCCHHCCCCCCCCCCCCCCCCCHHH
VLSISQMLYDFGKVASQVRAESAGAAEEQANVLLSIDSVAHETANAIVQVQAAQQMVEAA
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
EEQLVALNGIGKLTRQRNDEGATSMSDVVQTDARIEAARSQLAQYQADLDSAKASLMSML
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GWNSLNAISNDFPHKLDGSCEQAKPDDRLVPAVLAAWAQANVAQANLDYANAQMTPTISL
CCCHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHCCCCCCCCCCCEEEEC
EPSVQHYLNDKYPSHDVLDKTQYTAMVKVEMPIYQGGGLTARRNAASHAVESAQSAIQRT
CCHHHHHHCCCCCCCHHHCCCCCEEEEEEEECEECCCCCCCHHHHHHHHHHHHHHHHHHH
RLEVRRKLLDSRSQSMSLASALQILRRQQQLSERTRELYQQQYLDLGSRPLLDVLNAEQE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
VYQARFAELQIQSQLRQLQLNCLYNTGTLRQAFALNNRRIQSVEIQP
HHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA