Click here to switch to the map view.

The map label for this gene is mreD [H]

Identifier: 218550532

GI number: 218550532

Start: 3313490

End: 3313978

Strand: Reverse

Name: mreD [H]

Synonym: EFER_3226

Alternate gene names: 218550532

Gene position: 3313978-3313490 (Counterclockwise)

Preceding gene: 218550533

Following gene: 218550531

Centisome position: 72.22

GC content: 49.9

Gene sequence:

>489_bases
GTGGCCAGTTATCGCAGTCAGGGGCGCTGGGTAATCTGGCTCTCTTTCCTTATAGCTTTGTTACTGCAAATCATGCCCTG
GCCGGAGAATATCATTGTTTTCCGGCCTAATTGGGTACTGCTTATACTGCTCTACTGGATACTCGCTCTGCCGCACCGCG
TAAATGTGGGCACAGGTTTTGTGATGGGTGCCATACTGGATCTCATCAGCGGTTCAACACTGGGGGTGCGTGCGCTTTCA
ATGAGCATCGTCGCCTATCTGGTGGCACTTAAGTACCAGCTTTTCCGTAACCTTGCATTATGGCAGCAGGCGCTGGTCGT
CATGTTGCTTTCGCTGGTGGTGGATATTATTGTTTTCTGGGCAGAGTTTTTAGTGATCAACGTCTCTTTCAGACCCGAAG
TGTTCTGGAGTAGTGTAGTTAATGGCGTGCTCTGGCCGTGGATTTTCTTGCTGATGCGAAAAGTTCGCCAGCAGTTTGCA
GTGCAATAA

Upstream 100 bases:

>100_bases
CGGCTACTCAACCTGCAACGCCGCCAGCTGCTGCATCAGGGCAGGCGGTCACTCCGCCACCTGCAACGACGACGCCTGCG
CGCGCGCCGGGGAGGCAGTA

Downstream 100 bases:

>100_bases
GTGCATTAAAGGTTTCTATGACTTCTCTGTATTTAGCTTCCGGTTCTCCGCGTCGTCAGGAGTTACTTGCGCAACTTGGC
GTTACCTTTGAACGTATTGT

Product: rod shape-determining protein MreD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 162; Mature: 161

Protein sequence:

>162_residues
MASYRSQGRWVIWLSFLIALLLQIMPWPENIIVFRPNWVLLILLYWILALPHRVNVGTGFVMGAILDLISGSTLGVRALS
MSIVAYLVALKYQLFRNLALWQQALVVMLLSLVVDIIVFWAEFLVINVSFRPEVFWSSVVNGVLWPWIFLLMRKVRQQFA
VQ

Sequences:

>Translated_162_residues
MASYRSQGRWVIWLSFLIALLLQIMPWPENIIVFRPNWVLLILLYWILALPHRVNVGTGFVMGAILDLISGSTLGVRALS
MSIVAYLVALKYQLFRNLALWQQALVVMLLSLVVDIIVFWAEFLVINVSFRPEVFWSSVVNGVLWPWIFLLMRKVRQQFA
VQ
>Mature_161_residues
ASYRSQGRWVIWLSFLIALLLQIMPWPENIIVFRPNWVLLILLYWILALPHRVNVGTGFVMGAILDLISGSTLGVRALSM
SIVAYLVALKYQLFRNLALWQQALVVMLLSLVVDIIVFWAEFLVINVSFRPEVFWSSVVNGVLWPWIFLLMRKVRQQFAV
Q

Specific function: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins [H]

COG id: COG2891

COG function: function code M; Cell shape-determining protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mreD family [H]

Homologues:

Organism=Escherichia coli, GI1789647, Length=162, Percent_Identity=96.9135802469136, Blast_Score=288, Evalue=2e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007227 [H]

Pfam domain/function: PF04093 MreD [H]

EC number: NA

Molecular weight: Translated: 18776; Mature: 18645

Theoretical pI: Translated: 10.98; Mature: 10.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASYRSQGRWVIWLSFLIALLLQIMPWPENIIVFRPNWVLLILLYWILALPHRVNVGTGF
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHCCCCCCCCHHH
VMGAILDLISGSTLGVRALSMSIVAYLVALKYQLFRNLALWQQALVVMLLSLVVDIIVFW
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AEFLVINVSFRPEVFWSSVVNGVLWPWIFLLMRKVRQQFAVQ
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ASYRSQGRWVIWLSFLIALLLQIMPWPENIIVFRPNWVLLILLYWILALPHRVNVGTGF
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHCCCCCCCCHHH
VMGAILDLISGSTLGVRALSMSIVAYLVALKYQLFRNLALWQQALVVMLLSLVVDIIVFW
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AEFLVINVSFRPEVFWSSVVNGVLWPWIFLLMRKVRQQFAVQ
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]