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The map label for this gene is tldD [H]

Identifier: 218550528

GI number: 218550528

Start: 3305973

End: 3307418

Strand: Reverse

Name: tldD [H]

Synonym: EFER_3222

Alternate gene names: 218550528

Gene position: 3307418-3305973 (Counterclockwise)

Preceding gene: 218550529

Following gene: 218550526

Centisome position: 72.08

GC content: 52.84

Gene sequence:

>1446_bases
ATGAGTCTTAACCTGGTAAGTGAACAACTGCTAACCGCGAATGGCCTGAAGCATCAGGATCTGTTCGCCATTCTCGGTCA
ACTGGCCGAACGTCGCCTGGATTATGGCGATCTCTATTTTCAGTCGAGCTATCACGAATCCTGGGTTTTAGAAGATCGCA
TCATTAAAGATGGTTCTTATAACATCGATCAGGGTGTCGGTGTTCGGGCGATCAGCGGTGAGAAAACAGGCTTTGCCTAT
GCCGATCAGATAAGTCTGCTGGCACTTGAACAGAGCGCCCAGGCCGCGCGCACTATTGTCCGTGACAGTGGTGATGGAAA
AGTACAAACCCTGGGCGCTGTTGAACACTCCCCGCTGTATACCGCTGTTGATCCGCTGCAAAGCATGAGTCGTGAAGAGA
AGCTGGATATCCTGCGCCGCGTCGATAAGGTCGCTCGCGAAGCGGACAAGCGCGTACAGGAAGTGACTGCCAGCCTGAGT
GGTGTCTATGAATTAATCTTGGTTGCTGCCACTGACGGTACGCTGGCAGCCGATGTTCGCCCCCTGGTGCGCTTGTCTGT
CAGTGTGCTGGTAGAAGAAGACGGCAAACGTGAACGCGGCGCAAGCGGTGGTGGCGGTCGTTTTGGTTATGAATTTTTCC
TTGCAGATCTGGACGGTGAAGTCCGTGCAGACGCCTGGGCGAAAGAAGCGGTGCGTATGGCGCTGGTCAATCTTTCAGCT
GTTGCGGCACCAGCAGGGACAATGCCGGTAGTTCTCGGTGCAGGCTGGCCGGGGGTATTGTTGCATGAAGCGGTCGGACA
CGGGCTGGAAGGTGACTTTAACCGCCGTGGCACTTCCGTCTTTAGTGGTCAGGTGGGTGAGCTGGTTGCCTCAACGCTGT
GTACTGTGGTTGATGACGGTACGATGGTTGATCGCCGTGGTTCGGTGGCGATTGATGATGAAGGCACTCCGGGTCAGTAC
AACGTGCTGATTGAAAACGGCATTCTGAAAGGCTACATGCAGGATAAACTCAACGCACGTCTAATGGGCATGACGCCGAC
CGGGAATGGTCGCCGTGAATCTTATGCTCATTTGCCTATGCCGCGTATGACCAATACTTACATGCTGCCAGGCAAATCTA
CTCCGCAGGAAATTATTGAATCTGTTGAATATGGTATTTATGCGCCGAACTTTGGTGGCGGCCAGGTTGATATCACTTCC
GGTAAATTCGTTTTCTCCACCTCAGAAGCGTATCTGATTGAAAATGGCAAAGTGACGAAACCGGTAAAAGGTGCAACGTT
GATCGGTTCTGGGATCGAAACCATGCAGCAGATCTCCATGGTCGGCAACGACCTTAAACTGGATAATGGCGTTGGTGTCT
GCGGCAAAGAGGGGCAAAGTCTGCCTGTGGGGGTAGGGCAACCTACACTCAAAGTTGATAACCTGACGGTTGGTGGTACA
GCGTAA

Upstream 100 bases:

>100_bases
CCAATGAGCAGGAACGAAACCGTAAGCTGGTAAGGTGTTAAAGCCGCATCCGGCAGCTGTAAAAATCCTCTACCGCAGTA
ACTAACGAGTAGCAAAAACG

Downstream 100 bases:

>100_bases
TCTGTGCAGGCCTGATACGACGTCAGCGTCGTATCAGGCACAGGTCGCCACCAGATGTGACATGAGTGCTGATAGTTAAT
TACTTCTCTTTTCCTCGCCC

Product: protease TldD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 481; Mature: 480

Protein sequence:

>481_residues
MSLNLVSEQLLTANGLKHQDLFAILGQLAERRLDYGDLYFQSSYHESWVLEDRIIKDGSYNIDQGVGVRAISGEKTGFAY
ADQISLLALEQSAQAARTIVRDSGDGKVQTLGAVEHSPLYTAVDPLQSMSREEKLDILRRVDKVAREADKRVQEVTASLS
GVYELILVAATDGTLAADVRPLVRLSVSVLVEEDGKRERGASGGGGRFGYEFFLADLDGEVRADAWAKEAVRMALVNLSA
VAAPAGTMPVVLGAGWPGVLLHEAVGHGLEGDFNRRGTSVFSGQVGELVASTLCTVVDDGTMVDRRGSVAIDDEGTPGQY
NVLIENGILKGYMQDKLNARLMGMTPTGNGRRESYAHLPMPRMTNTYMLPGKSTPQEIIESVEYGIYAPNFGGGQVDITS
GKFVFSTSEAYLIENGKVTKPVKGATLIGSGIETMQQISMVGNDLKLDNGVGVCGKEGQSLPVGVGQPTLKVDNLTVGGT
A

Sequences:

>Translated_481_residues
MSLNLVSEQLLTANGLKHQDLFAILGQLAERRLDYGDLYFQSSYHESWVLEDRIIKDGSYNIDQGVGVRAISGEKTGFAY
ADQISLLALEQSAQAARTIVRDSGDGKVQTLGAVEHSPLYTAVDPLQSMSREEKLDILRRVDKVAREADKRVQEVTASLS
GVYELILVAATDGTLAADVRPLVRLSVSVLVEEDGKRERGASGGGGRFGYEFFLADLDGEVRADAWAKEAVRMALVNLSA
VAAPAGTMPVVLGAGWPGVLLHEAVGHGLEGDFNRRGTSVFSGQVGELVASTLCTVVDDGTMVDRRGSVAIDDEGTPGQY
NVLIENGILKGYMQDKLNARLMGMTPTGNGRRESYAHLPMPRMTNTYMLPGKSTPQEIIESVEYGIYAPNFGGGQVDITS
GKFVFSTSEAYLIENGKVTKPVKGATLIGSGIETMQQISMVGNDLKLDNGVGVCGKEGQSLPVGVGQPTLKVDNLTVGGT
A
>Mature_480_residues
SLNLVSEQLLTANGLKHQDLFAILGQLAERRLDYGDLYFQSSYHESWVLEDRIIKDGSYNIDQGVGVRAISGEKTGFAYA
DQISLLALEQSAQAARTIVRDSGDGKVQTLGAVEHSPLYTAVDPLQSMSREEKLDILRRVDKVAREADKRVQEVTASLSG
VYELILVAATDGTLAADVRPLVRLSVSVLVEEDGKRERGASGGGGRFGYEFFLADLDGEVRADAWAKEAVRMALVNLSAV
AAPAGTMPVVLGAGWPGVLLHEAVGHGLEGDFNRRGTSVFSGQVGELVASTLCTVVDDGTMVDRRGSVAIDDEGTPGQYN
VLIENGILKGYMQDKLNARLMGMTPTGNGRRESYAHLPMPRMTNTYMLPGKSTPQEIIESVEYGIYAPNFGGGQVDITSG
KFVFSTSEAYLIENGKVTKPVKGATLIGSGIETMQQISMVGNDLKLDNGVGVCGKEGQSLPVGVGQPTLKVDNLTVGGTA

Specific function: Suppresses the inhibitory activity of the carbon storage regulator (CsrA) [H]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=481, Percent_Identity=99.3762993762994, Blast_Score=968, Evalue=0.0,
Organism=Escherichia coli, GI1790682, Length=408, Percent_Identity=20.343137254902, Blast_Score=70, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 51351; Mature: 51220

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLNLVSEQLLTANGLKHQDLFAILGQLAERRLDYGDLYFQSSYHESWVLEDRIIKDGSY
CCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCEEEHHHEECCCCC
NIDQGVGVRAISGEKTGFAYADQISLLALEQSAQAARTIVRDSGDGKVQTLGAVEHSPLY
CCCCCCCEEEECCCCCCCEECCCEEEEEEHHHHHHHHHHHHCCCCCCEEEEECCCCCCCH
TAVDPLQSMSREEKLDILRRVDKVAREADKRVQEVTASLSGVYELILVAATDGTLAADVR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCHHHHH
PLVRLSVSVLVEEDGKRERGASGGGGRFGYEFFLADLDGEVRADAWAKEAVRMALVNLSA
HHHHHEEEEEEECCCCHHCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHH
VAAPAGTMPVVLGAGWPGVLLHEAVGHGLEGDFNRRGTSVFSGQVGELVASTLCTVVDDG
HCCCCCCCCEEEECCCCHHHHHHHHCCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHCCC
TMVDRRGSVAIDDEGTPGQYNVLIENGILKGYMQDKLNARLMGMTPTGNGRRESYAHLPM
CEEECCCCEEECCCCCCCEEEEEEECCHHHHHHHHCCCCEEEEECCCCCCCCCCEECCCC
PRMTNTYMLPGKSTPQEIIESVEYGIYAPNFGGGQVDITSGKFVFSTSEAYLIENGKVTK
CCCCCEEECCCCCCHHHHHHHHHCCEECCCCCCCEEEEECCEEEEECCCEEEEECCCCCC
PVKGATLIGSGIETMQQISMVGNDLKLDNGVGVCGKEGQSLPVGVGQPTLKVDNLTVGGT
CCCCCEEECCHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCCEEECCEECCCC
A
C
>Mature Secondary Structure 
SLNLVSEQLLTANGLKHQDLFAILGQLAERRLDYGDLYFQSSYHESWVLEDRIIKDGSY
CCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCEEEHHHEECCCCC
NIDQGVGVRAISGEKTGFAYADQISLLALEQSAQAARTIVRDSGDGKVQTLGAVEHSPLY
CCCCCCCEEEECCCCCCCEECCCEEEEEEHHHHHHHHHHHHCCCCCCEEEEECCCCCCCH
TAVDPLQSMSREEKLDILRRVDKVAREADKRVQEVTASLSGVYELILVAATDGTLAADVR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCHHHHH
PLVRLSVSVLVEEDGKRERGASGGGGRFGYEFFLADLDGEVRADAWAKEAVRMALVNLSA
HHHHHEEEEEEECCCCHHCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHH
VAAPAGTMPVVLGAGWPGVLLHEAVGHGLEGDFNRRGTSVFSGQVGELVASTLCTVVDDG
HCCCCCCCCEEEECCCCHHHHHHHHCCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHCCC
TMVDRRGSVAIDDEGTPGQYNVLIENGILKGYMQDKLNARLMGMTPTGNGRRESYAHLPM
CEEECCCCEEECCCCCCCEEEEEEECCHHHHHHHHCCCCEEEEECCCCCCCCCCEECCCC
PRMTNTYMLPGKSTPQEIIESVEYGIYAPNFGGGQVDITSGKFVFSTSEAYLIENGKVTK
CCCCCEEECCCCCCHHHHHHHHHCCEECCCCCCCEEEEECCEEEEECCCEEEEECCCCCC
PVKGATLIGSGIETMQQISMVGNDLKLDNGVGVCGKEGQSLPVGVGQPTLKVDNLTVGGT
CCCCCEEECCHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCCEEECCEECCCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]