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The map label for this gene is degQ [H]

Identifier: 218550511

GI number: 218550511

Start: 3291357

End: 3292724

Strand: Direct

Name: degQ [H]

Synonym: EFER_3205

Alternate gene names: 218550511

Gene position: 3291357-3292724 (Clockwise)

Preceding gene: 218550510

Following gene: 218550512

Centisome position: 71.73

GC content: 49.78

Gene sequence:

>1368_bases
ATGAAAAAGCAAACCCAGCTGTTGAGTGTATTAGCGTTAAGTGTCGGGTTAATTCTCGCGGCACCGTATCAAGCCGCAGC
ATCAATTCCCGGCCAGGTTGCTGGTCAGGCACCTTTACCCAGCCTCGCCCCCATGTTGGAAAAAGTATTACCTGCGGTGG
TCAGCGTTCGAGTCGAAGGCACAGCTGTTCAAAGCCAGAATATACCGGAAGAATTCAAAAAGTTTTTTGGCGATGACCTG
CCAGAAGGACCTTCACAGCCTTTTGAAGGACTCGGATCAGGTGTCATTATCGATGCAGCTAAAGGCTATGTTCTCACCAA
TAACCATGTCATAAATCAGGCGCAGAAAATCAGCATCCAGCTCAATGATGGGCGCGAGTTCGATGCGAAACTGATTGGTA
GCGACGATCAGAGCGATATCGCCCTGTTGCAAATTCAAAATCCCAGCAAACTGACACAAATTACCATTGCTGATTCCGAC
AAATTACGTGTCGGTGATTTTGCCGTGGCGGTGGGTAACCCTTTTGGTCTGGGGCAAACCGCGACCTCCGGGATTATCTC
GGCGTTAGGTCGTAGCGGGCTAAATCTGGAAGGTCTGGAAAACTTTATTCAAACTGACGCCTCAATCAACCGGGGTAACT
CTGGTGGTGCCCTTATTAACCTTAATGGCGAACTGATTGGGATTAATACTGCTATTCTGGCACCAGGTGGGGGCAGTGTA
GGTATTGGCTTCGCCATCCCAAGTAATATGGCGCGCACTCTGGCTCAGCAACTGATTGATTTCGGCGAGATAAAACGTGG
GTTGCTCGGAATTAAAGGTACGGAGATGACCGCTGATATCGCCAAAGCGTTCAAGCTGGATGTGCAACGTGGCGCATTTG
TCAGTGAAGTCATGCCAAACTCCGGTTCAGCGAAAGCAGGTATCAAGTCAGGCGATATCATCACTAGTCTCAATGGGAAG
CCATTGACCAGCTTTGCCGAGCTACGTTCCCGCATTGCCACGACCGAACCTGGCACTAAAGTCAAACTGGGCCTGTTGCG
TAATGGCAAGCCACTGGAGGTTGAAGTCACGCTGGATACCAGCACCTCATCTTCTGCCAGCGCAGAGATGATCGCCCCAG
CGCTACAGGGCGCAACGCTTAGCGATACACAACTAAAAGATGGTACCAAAGGTATCCGCATTGAAAATATTGAGAAAAGC
AGTCCGGCGGCACAATCAGGCCTGCAGAAAGACGATGTGATTATTGGAATTAACCGTGATCGCGTGAACTCAATTGCTGA
GATGCGTAAAACACTGGAAGCAAAACCGGCGATCATTGCTTTGCAGATTTTGCGTGGCAACGACACCCTTTATCTCCTCC
TGCGTTAA

Upstream 100 bases:

>100_bases
CATTTAATCTGACATCTGATTGTTCGCAGATTAGAAATTCAATAACATCAATCTGTTTTGAATCGATTTTCCTTATCACT
CAAGGTACGAGAGCCGGAAT

Downstream 100 bases:

>100_bases
TGTAGCAAACCGGGCATCAGCCTTACGTGTGATGTCCGGTTAACTCATGGTATGCTGCTCCCGTTCCTTATTTTTATGAC
GCCTCCATCATGTTTGTGAA

Product: serine endoprotease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 455; Mature: 455

Protein sequence:

>455_residues
MKKQTQLLSVLALSVGLILAAPYQAAASIPGQVAGQAPLPSLAPMLEKVLPAVVSVRVEGTAVQSQNIPEEFKKFFGDDL
PEGPSQPFEGLGSGVIIDAAKGYVLTNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQNPSKLTQITIADSD
KLRVGDFAVAVGNPFGLGQTATSGIISALGRSGLNLEGLENFIQTDASINRGNSGGALINLNGELIGINTAILAPGGGSV
GIGFAIPSNMARTLAQQLIDFGEIKRGLLGIKGTEMTADIAKAFKLDVQRGAFVSEVMPNSGSAKAGIKSGDIITSLNGK
PLTSFAELRSRIATTEPGTKVKLGLLRNGKPLEVEVTLDTSTSSSASAEMIAPALQGATLSDTQLKDGTKGIRIENIEKS
SPAAQSGLQKDDVIIGINRDRVNSIAEMRKTLEAKPAIIALQILRGNDTLYLLLR

Sequences:

>Translated_455_residues
MKKQTQLLSVLALSVGLILAAPYQAAASIPGQVAGQAPLPSLAPMLEKVLPAVVSVRVEGTAVQSQNIPEEFKKFFGDDL
PEGPSQPFEGLGSGVIIDAAKGYVLTNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQNPSKLTQITIADSD
KLRVGDFAVAVGNPFGLGQTATSGIISALGRSGLNLEGLENFIQTDASINRGNSGGALINLNGELIGINTAILAPGGGSV
GIGFAIPSNMARTLAQQLIDFGEIKRGLLGIKGTEMTADIAKAFKLDVQRGAFVSEVMPNSGSAKAGIKSGDIITSLNGK
PLTSFAELRSRIATTEPGTKVKLGLLRNGKPLEVEVTLDTSTSSSASAEMIAPALQGATLSDTQLKDGTKGIRIENIEKS
SPAAQSGLQKDDVIIGINRDRVNSIAEMRKTLEAKPAIIALQILRGNDTLYLLLR
>Mature_455_residues
MKKQTQLLSVLALSVGLILAAPYQAAASIPGQVAGQAPLPSLAPMLEKVLPAVVSVRVEGTAVQSQNIPEEFKKFFGDDL
PEGPSQPFEGLGSGVIIDAAKGYVLTNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQNPSKLTQITIADSD
KLRVGDFAVAVGNPFGLGQTATSGIISALGRSGLNLEGLENFIQTDASINRGNSGGALINLNGELIGINTAILAPGGGSV
GIGFAIPSNMARTLAQQLIDFGEIKRGLLGIKGTEMTADIAKAFKLDVQRGAFVSEVMPNSGSAKAGIKSGDIITSLNGK
PLTSFAELRSRIATTEPGTKVKLGLLRNGKPLEVEVTLDTSTSSSASAEMIAPALQGATLSDTQLKDGTKGIRIENIEKS
SPAAQSGLQKDDVIIGINRDRVNSIAEMRKTLEAKPAIIALQILRGNDTLYLLLR

Specific function: Protease with a shared specificity with degP [H]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI22129776, Length=316, Percent_Identity=36.7088607594937, Blast_Score=168, Evalue=1e-41,
Organism=Homo sapiens, GI4506141, Length=298, Percent_Identity=35.9060402684564, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI24308541, Length=305, Percent_Identity=30.8196721311475, Blast_Score=149, Evalue=6e-36,
Organism=Homo sapiens, GI7019477, Length=296, Percent_Identity=33.1081081081081, Blast_Score=131, Evalue=1e-30,
Organism=Escherichia coli, GI1789629, Length=455, Percent_Identity=90.3296703296703, Blast_Score=799, Evalue=0.0,
Organism=Escherichia coli, GI1786356, Length=457, Percent_Identity=56.4551422319475, Blast_Score=509, Evalue=1e-145,
Organism=Escherichia coli, GI1789630, Length=316, Percent_Identity=42.0886075949367, Blast_Score=216, Evalue=2e-57,
Organism=Drosophila melanogaster, GI24646839, Length=289, Percent_Identity=33.2179930795848, Blast_Score=125, Evalue=4e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.-

Molecular weight: Translated: 47550; Mature: 47550

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKQTQLLSVLALSVGLILAAPYQAAASIPGQVAGQAPLPSLAPMLEKVLPAVVSVRVEG
CCHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHEEEECC
TAVQSQNIPEEFKKFFGDDLPEGPSQPFEGLGSGVIIDAAKGYVLTNNHVINQAQKISIQ
EEECCCCCCHHHHHHHCCCCCCCCCCCHHHCCCCEEEECCCCEEEECCCEECCEEEEEEE
LNDGREFDAKLIGSDDQSDIALLQIQNPSKLTQITIADSDKLRVGDFAVAVGNPFGLGQT
ECCCCCCCEEEECCCCCCCEEEEEECCCCCEEEEEEECCCCEEECEEEEEECCCCCCCHH
ATSGIISALGRSGLNLEGLENFIQTDASINRGNSGGALINLNGELIGINTAILAPGGGSV
HHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEECCEEEEEEEEEEECCCCCE
GIGFAIPSNMARTLAQQLIDFGEIKRGLLGIKGTEMTADIAKAFKLDVQRGAFVSEVMPN
EEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHCCC
SGSAKAGIKSGDIITSLNGKPLTSFAELRSRIATTEPGTKVKLGLLRNGKPLEVEVTLDT
CCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEEEEEEC
STSSSASAEMIAPALQGATLSDTQLKDGTKGIRIENIEKSSPAAQSGLQKDDVIIGINRD
CCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCCCCHHHHCCCCCCEEEEECHH
RVNSIAEMRKTLEAKPAIIALQILRGNDTLYLLLR
HHHHHHHHHHHHCCCCEEEEEEEEECCCEEEEEEC
>Mature Secondary Structure
MKKQTQLLSVLALSVGLILAAPYQAAASIPGQVAGQAPLPSLAPMLEKVLPAVVSVRVEG
CCHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHEEEECC
TAVQSQNIPEEFKKFFGDDLPEGPSQPFEGLGSGVIIDAAKGYVLTNNHVINQAQKISIQ
EEECCCCCCHHHHHHHCCCCCCCCCCCHHHCCCCEEEECCCCEEEECCCEECCEEEEEEE
LNDGREFDAKLIGSDDQSDIALLQIQNPSKLTQITIADSDKLRVGDFAVAVGNPFGLGQT
ECCCCCCCEEEECCCCCCCEEEEEECCCCCEEEEEEECCCCEEECEEEEEECCCCCCCHH
ATSGIISALGRSGLNLEGLENFIQTDASINRGNSGGALINLNGELIGINTAILAPGGGSV
HHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEECCEEEEEEEEEEECCCCCE
GIGFAIPSNMARTLAQQLIDFGEIKRGLLGIKGTEMTADIAKAFKLDVQRGAFVSEVMPN
EEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHCCC
SGSAKAGIKSGDIITSLNGKPLTSFAELRSRIATTEPGTKVKLGLLRNGKPLEVEVTLDT
CCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEEEEEEC
STSSSASAEMIAPALQGATLSDTQLKDGTKGIRIENIEKSSPAAQSGLQKDDVIIGINRD
CCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCCCCHHHHCCCCCCEEEEECHH
RVNSIAEMRKTLEAKPAIIALQILRGNDTLYLLLR
HHHHHHHHHHHHCCCCEEEEEEEEECCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8576051; 9278503 [H]