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The map label for this gene is npr [H]

Identifier: 218550489

GI number: 218550489

Start: 3267392

End: 3267664

Strand: Direct

Name: npr [H]

Synonym: EFER_3183

Alternate gene names: 218550489

Gene position: 3267392-3267664 (Clockwise)

Preceding gene: 218550488

Following gene: 218550490

Centisome position: 71.21

GC content: 50.55

Gene sequence:

>273_bases
ATGACCGTCAAACAAACTGTTGAAGTGACTAATAAGCTGGGTATGCACGCCCGGCCCGCCATGAAACTGTTTGAGCTAAT
GCAGGGCTTTGATGCAGAAGTTCTGCTGCGTAATGATGAGGGCACGGAAGCCGAAGCTAACAGCGTGATTGCCTTATTGA
TGCTGGACTCTGCGAAAGGTCGTCAAATCGAAATTGAAGCAACCGGGCCGCAGGAAGTTGAAGCACTGGCAGCAGTTATC
GCTCTCTTCGAGTCAGGTTTCGACGAAGACTAG

Upstream 100 bases:

>100_bases
AACACCGTTCGGTGTATATTGCAGAGCAACTGGCAGACTACTTCCGCTCGCGCGGTAAAAACGTACAGTCACGCCACCGC
ACGCTGGAAAAACGCAAAAC

Downstream 100 bases:

>100_bases
TTATTTTACTCACCATTTCTCCCCCATCTCAAAAGCGCCACCCGGCGTTTTTCTATCTCCCCTTATTACTTGTACATTTA
GTGCGCTTTTACCACTCATA

Product: phosphohistidinoprotein-hexose phosphotransferase component of N-regulated PTS system (Npr)

Products: NA

Alternate protein names: Nitrogen-related HPr [H]

Number of amino acids: Translated: 90; Mature: 89

Protein sequence:

>90_residues
MTVKQTVEVTNKLGMHARPAMKLFELMQGFDAEVLLRNDEGTEAEANSVIALLMLDSAKGRQIEIEATGPQEVEALAAVI
ALFESGFDED

Sequences:

>Translated_90_residues
MTVKQTVEVTNKLGMHARPAMKLFELMQGFDAEVLLRNDEGTEAEANSVIALLMLDSAKGRQIEIEATGPQEVEALAAVI
ALFESGFDED
>Mature_89_residues
TVKQTVEVTNKLGMHARPAMKLFELMQGFDAEVLLRNDEGTEAEANSVIALLMLDSAKGRQIEIEATGPQEVEALAAVIA
LFESGFDED

Specific function: Component of the phosphoenolpyruvate-dependent nitrogen- metabolic phosphotransferase system (nitrogen-metabolic PTS), that seems to be involved in regulating nitrogen metabolism. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the p

COG id: COG1925

COG function: function code G; Phosphotransferase system, HPr-related proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPr domain [H]

Homologues:

Organism=Escherichia coli, GI1789599, Length=90, Percent_Identity=95.5555555555556, Blast_Score=174, Evalue=1e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001020
- InterPro:   IPR005698
- InterPro:   IPR000032
- InterPro:   IPR002114 [H]

Pfam domain/function: PF00381 PTS-HPr [H]

EC number: NA

Molecular weight: Translated: 9795; Mature: 9664

Theoretical pI: Translated: 4.02; Mature: 4.02

Prosite motif: PS00369 PTS_HPR_HIS ; PS00589 PTS_HPR_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVKQTVEVTNKLGMHARPAMKLFELMQGFDAEVLLRNDEGTEAEANSVIALLMLDSAKG
CCCHHHHHHHHHCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCCCCEEEEEEECCCCC
RQIEIEATGPQEVEALAAVIALFESGFDED
CEEEEEECCHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TVKQTVEVTNKLGMHARPAMKLFELMQGFDAEVLLRNDEGTEAEANSVIALLMLDSAKG
CCHHHHHHHHHCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCCCCEEEEEEECCCCC
RQIEIEATGPQEVEALAAVIALFESGFDED
CEEEEEECCHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]