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The map label for this gene is glmM [H]

Identifier: 218550459

GI number: 218550459

Start: 3242307

End: 3243644

Strand: Reverse

Name: glmM [H]

Synonym: EFER_3153

Alternate gene names: 218550459

Gene position: 3243644-3242307 (Counterclockwise)

Preceding gene: 218550460

Following gene: 218550458

Centisome position: 70.69

GC content: 53.21

Gene sequence:

>1338_bases
ATGAGTAATCGTAAATATTTCGGTACCGATGGGATTCGTGGTCGTGTAGGGGATGCGCCGATCACCCCTGATTTTGTACT
TAAGTTGGGTTGGGCCGCCGGTAAAGTGCTGGCGCGCCACGGCTCGCGTAAGATCATTATTGGTAAAGACACGCGTATTT
CTGGCTATATGCTGGAGTCAGCACTGGAAGCGGGTCTGGCGGCTGCGGGCCTTTCCGCACTCTTTACAGGCCCGATGCCT
ACACCTGCCGTGGCTTATCTGACGCGTACCTTCCGCGCAGAGGCCGGGATTGTAATTTCTGCATCGCATAACCCATTCTA
CGATAACGGCATTAAATTCTTTTCTATTGACGGTACTAAGCTGCCGGATGCAGTTGAAGAAGCCATCGAAGCGGAAATGG
AAAAAGAGATCAGCTGTGTTGATTCGGCAGAACTGGGTAAAGCCAGCCGTATCGTTGATGCCGCGGGTCGCTATATCGAG
TTTTGCAAAGCCACGTTCCCGAACGAACTTAGCCTCAGTGAACTGAAAATTGTGGTGGATTGCGCAAATGGCGCGACTTA
TCACATCGCGCCGAACGTACTGCGCGAACTGGGGGCGAACGTTATCGCTATCGGTTGTGAGCCGAACGGCGTAAACATCA
ATGCCGAAGTGGGGGCAACTGATGTTCGTGCGTTACAGGCGCGCGTACTGGCTGAAAAAGCAGATCTTGGTATCGCCTTT
GACGGTGACGGCGACCGCGTGATTATGGTTGACCATGAAGGCAATAAAGTCGATGGCGACCAGATTATGTATATCATCGC
GCGCGAAGGTCTGCGTCAGGGCCAACTGCGTGGTGGCGCGGTGGGTACATTGATGAGCAACATGGGGCTGGAACTCGCCC
TGAAACAGCTAGGAATTCCGTTTGCTCGTGCGAAAGTGGGCGATCGCTACGTACTGGAAAAAATGCAGGAGAAAGGCTGG
CGTATCGGTGCAGAGAACTCTGGTCATGTGATCCTGCTGGATAAAACCACAACCGGTGACGGCATCGTTGCTGGTTTGCA
GGTGCTGGCGGCGATGGCGCGTAACCATATGAGCCTGCACGACCTTTGCAGTGGTATGAAAATGTTCCCGCAGATTCTGG
TTAACGTGCGTTACACCGCAGGTAGTGGCGATCCGCTGGAGCATGAATCAGTCAAAGCTGTAACCGCAGAAGTTGAAGCG
GCGCTGGGTAGCCGTGGACGTGTGCTGTTGCGTAAATCCGGCACCGAACCGTTAATTCGCGTGATGGTAGAAGGCGAAGA
CGAAGAGCAGGTTACTGAATTTGCACACCGCATCGCTGATGCAGTAAAAGCCGTTTAA

Upstream 100 bases:

>100_bases
ATGCAAGGCGCGCACATCATTCGTGTTCATGACGTCAAAGAAACCGTAGAAGCGATGCGGGTGGTGGAAGCCACTCTGTC
TGCAAAGGAAAACAAACGCT

Downstream 100 bases:

>100_bases
AACAGTAGAAGGCTGGCTAAAAAGGCGGCGATTGTCGCCTTTTTTCTCAGCGAACACATCGGTTTTGCTGTTTTTTTCCG
CAGTTGATACAATGCGATAA

Product: phosphoglucosamine mutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 445; Mature: 444

Protein sequence:

>445_residues
MSNRKYFGTDGIRGRVGDAPITPDFVLKLGWAAGKVLARHGSRKIIIGKDTRISGYMLESALEAGLAAAGLSALFTGPMP
TPAVAYLTRTFRAEAGIVISASHNPFYDNGIKFFSIDGTKLPDAVEEAIEAEMEKEISCVDSAELGKASRIVDAAGRYIE
FCKATFPNELSLSELKIVVDCANGATYHIAPNVLRELGANVIAIGCEPNGVNINAEVGATDVRALQARVLAEKADLGIAF
DGDGDRVIMVDHEGNKVDGDQIMYIIAREGLRQGQLRGGAVGTLMSNMGLELALKQLGIPFARAKVGDRYVLEKMQEKGW
RIGAENSGHVILLDKTTTGDGIVAGLQVLAAMARNHMSLHDLCSGMKMFPQILVNVRYTAGSGDPLEHESVKAVTAEVEA
ALGSRGRVLLRKSGTEPLIRVMVEGEDEEQVTEFAHRIADAVKAV

Sequences:

>Translated_445_residues
MSNRKYFGTDGIRGRVGDAPITPDFVLKLGWAAGKVLARHGSRKIIIGKDTRISGYMLESALEAGLAAAGLSALFTGPMP
TPAVAYLTRTFRAEAGIVISASHNPFYDNGIKFFSIDGTKLPDAVEEAIEAEMEKEISCVDSAELGKASRIVDAAGRYIE
FCKATFPNELSLSELKIVVDCANGATYHIAPNVLRELGANVIAIGCEPNGVNINAEVGATDVRALQARVLAEKADLGIAF
DGDGDRVIMVDHEGNKVDGDQIMYIIAREGLRQGQLRGGAVGTLMSNMGLELALKQLGIPFARAKVGDRYVLEKMQEKGW
RIGAENSGHVILLDKTTTGDGIVAGLQVLAAMARNHMSLHDLCSGMKMFPQILVNVRYTAGSGDPLEHESVKAVTAEVEA
ALGSRGRVLLRKSGTEPLIRVMVEGEDEEQVTEFAHRIADAVKAV
>Mature_444_residues
SNRKYFGTDGIRGRVGDAPITPDFVLKLGWAAGKVLARHGSRKIIIGKDTRISGYMLESALEAGLAAAGLSALFTGPMPT
PAVAYLTRTFRAEAGIVISASHNPFYDNGIKFFSIDGTKLPDAVEEAIEAEMEKEISCVDSAELGKASRIVDAAGRYIEF
CKATFPNELSLSELKIVVDCANGATYHIAPNVLRELGANVIAIGCEPNGVNINAEVGATDVRALQARVLAEKADLGIAFD
GDGDRVIMVDHEGNKVDGDQIMYIIAREGLRQGQLRGGAVGTLMSNMGLELALKQLGIPFARAKVGDRYVLEKMQEKGWR
IGAENSGHVILLDKTTTGDGIVAGLQVLAAMARNHMSLHDLCSGMKMFPQILVNVRYTAGSGDPLEHESVKAVTAEVEAA
LGSRGRVLLRKSGTEPLIRVMVEGEDEEQVTEFAHRIADAVKAV

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate [H]

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI133922562, Length=368, Percent_Identity=26.0869565217391, Blast_Score=66, Evalue=8e-11,
Organism=Escherichia coli, GI1789566, Length=445, Percent_Identity=99.5505617977528, Blast_Score=900, Evalue=0.0,
Organism=Escherichia coli, GI1788361, Length=460, Percent_Identity=26.0869565217391, Blast_Score=100, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17535441, Length=305, Percent_Identity=27.5409836065574, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI17864244, Length=349, Percent_Identity=27.2206303724928, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841
- InterPro:   IPR006352 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.10 [H]

Molecular weight: Translated: 47575; Mature: 47444

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNRKYFGTDGIRGRVGDAPITPDFVLKLGWAAGKVLARHGSRKIIIGKDTRISGYMLES
CCCCCCCCCCCCCCCCCCCCCCHHHHHEECHHHHHHHHHCCCCEEEEECCCCCHHHHHHH
ALEAGLAAAGLSALFTGPMPTPAVAYLTRTFRAEAGIVISASHNPFYDNGIKFFSIDGTK
HHHHHHHHHCHHHHCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEEECCCC
LPDAVEEAIEAEMEKEISCVDSAELGKASRIVDAAGRYIEFCKATFPNELSLSELKIVVD
CCHHHHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEE
CANGATYHIAPNVLRELGANVIAIGCEPNGVNINAEVGATDVRALQARVLAEKADLGIAF
ECCCCEEEECHHHHHHCCCCEEEEECCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCEEE
DGDGDRVIMVDHEGNKVDGDQIMYIIAREGLRQGQLRGGAVGTLMSNMGLELALKQLGIP
CCCCCEEEEEECCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHCCHHHHHHHHCCC
FARAKVGDRYVLEKMQEKGWRIGAENSGHVILLDKTTTGDGIVAGLQVLAAMARNHMSLH
HHHHHCCHHHHHHHHHHCCCEECCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCHH
DLCSGMKMFPQILVNVRYTAGSGDPLEHESVKAVTAEVEAALGSRGRVLLRKSGTEPLIR
HHHHHHHHHHHHHEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEE
VMVEGEDEEQVTEFAHRIADAVKAV
EEECCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SNRKYFGTDGIRGRVGDAPITPDFVLKLGWAAGKVLARHGSRKIIIGKDTRISGYMLES
CCCCCCCCCCCCCCCCCCCCCHHHHHEECHHHHHHHHHCCCCEEEEECCCCCHHHHHHH
ALEAGLAAAGLSALFTGPMPTPAVAYLTRTFRAEAGIVISASHNPFYDNGIKFFSIDGTK
HHHHHHHHHCHHHHCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEEECCCC
LPDAVEEAIEAEMEKEISCVDSAELGKASRIVDAAGRYIEFCKATFPNELSLSELKIVVD
CCHHHHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEE
CANGATYHIAPNVLRELGANVIAIGCEPNGVNINAEVGATDVRALQARVLAEKADLGIAF
ECCCCEEEECHHHHHHCCCCEEEEECCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCEEE
DGDGDRVIMVDHEGNKVDGDQIMYIIAREGLRQGQLRGGAVGTLMSNMGLELALKQLGIP
CCCCCEEEEEECCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHCCHHHHHHHHCCC
FARAKVGDRYVLEKMQEKGWRIGAENSGHVILLDKTTTGDGIVAGLQVLAAMARNHMSLH
HHHHHCCHHHHHHHHHHCCCEECCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCHH
DLCSGMKMFPQILVNVRYTAGSGDPLEHESVKAVTAEVEAALGSRGRVLLRKSGTEPLIR
HHHHHHHHHHHHHEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEE
VMVEGEDEEQVTEFAHRIADAVKAV
EEECCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA