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The map label for this gene is mdcB [H]

Identifier: 218550432

GI number: 218550432

Start: 3213257

End: 3214144

Strand: Direct

Name: mdcB [H]

Synonym: EFER_3126

Alternate gene names: 218550432

Gene position: 3213257-3214144 (Clockwise)

Preceding gene: 218550431

Following gene: 218550433

Centisome position: 70.03

GC content: 44.93

Gene sequence:

>888_bases
ATGTATTCCACTGACAGTAATGCACAATGGATCGGTGAGTGCCTGTTAAAAGCTATATTAATGGAGGTTTGCGCCTGGCC
TAAACCAGGACTGGTCACTCCCCTTTCTCAGGGTGCGCATACTGATATGGATATTTGGTTATTTATTACCAGTTCATCTA
CCATTGCCCCCTGTTTTACCCTTTGTGCTATAGCAGGCGAAAACCATAACGGTGAATTAACAGAATTATTTCCCGTTATC
AGGAAAATTGGTATTCAGTATGAAAATAAATTGCTTAACGCTACGCAGCAAATTAATACCCAGCGTGGCATTTTATTTTC
TTCTGCTCTTCTTGCCGCTGTCGCTGGTTGGCTTTCTGCCCAAAAGCAGCCTCTGACTTATTGCGCCTTAAGTCAGAACA
TCAGCACGCTTTGCCAAAATCTCTGTCGCAATGATTTTGCTCAACTCAATCAACGGGCAGCTAAAACGCAAGGCGAAAAA
CTCTATTCTGAGTTTGGCATTACCGGAATTCGTGGTGAGGCAGAACACGGTTTTCCTCTGGTATGCAACATTGCTCTTCC
GGCTTTACATCAGGCATTAGCGCATCAACTGAGTTGGCGCGAGTCGCTTATTCATACTCTGCTGGCGTTGATGGCTTGTT
GTGAAGATACCACTGTTTTGTCACGTGGTGGACAAAAGGCACTGAGAGAAATGCAGTCCAGGGCGCAACGACTTGTTGAT
CAGGGCGGCATGTTACAACCGGATATCGGCAAGAAACTGACTGACTTTAACCAATGGTGTGTGGATAACTGGATAAGCCC
CGGCGGTTGTGCCGATTTACTGGCGCTAACTTTGGCTATGTATTTTCTATGCCAGGGTGATAAACACTTAATACAGGAAA
ATATATGA

Upstream 100 bases:

>100_bases
TAATTACGTTACCCGGAGCGTAATTGTTCTGTGATTTCTTCAATGCTACTTTTTGCTCGTGTTATTAATTTTTTAGTATA
CACAAGCAAAGGAAATAGCC

Downstream 100 bases:

>100_bases
GTATTTATCTCTATACATTATTTACCTACGGCTTAACCATTCTAATCTCTTTTGCGGTGGTGGGCATTATTGTTGGGGTA
AATAAGCTAATGAATAAGTT

Product: triphosphoribosyl-dephospho-CoA transferase

Products: NA

Alternate protein names: 2-(5''-triphosphoribosyl)-3'-dephospho-CoA synthase [H]

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MYSTDSNAQWIGECLLKAILMEVCAWPKPGLVTPLSQGAHTDMDIWLFITSSSTIAPCFTLCAIAGENHNGELTELFPVI
RKIGIQYENKLLNATQQINTQRGILFSSALLAAVAGWLSAQKQPLTYCALSQNISTLCQNLCRNDFAQLNQRAAKTQGEK
LYSEFGITGIRGEAEHGFPLVCNIALPALHQALAHQLSWRESLIHTLLALMACCEDTTVLSRGGQKALREMQSRAQRLVD
QGGMLQPDIGKKLTDFNQWCVDNWISPGGCADLLALTLAMYFLCQGDKHLIQENI

Sequences:

>Translated_295_residues
MYSTDSNAQWIGECLLKAILMEVCAWPKPGLVTPLSQGAHTDMDIWLFITSSSTIAPCFTLCAIAGENHNGELTELFPVI
RKIGIQYENKLLNATQQINTQRGILFSSALLAAVAGWLSAQKQPLTYCALSQNISTLCQNLCRNDFAQLNQRAAKTQGEK
LYSEFGITGIRGEAEHGFPLVCNIALPALHQALAHQLSWRESLIHTLLALMACCEDTTVLSRGGQKALREMQSRAQRLVD
QGGMLQPDIGKKLTDFNQWCVDNWISPGGCADLLALTLAMYFLCQGDKHLIQENI
>Mature_295_residues
MYSTDSNAQWIGECLLKAILMEVCAWPKPGLVTPLSQGAHTDMDIWLFITSSSTIAPCFTLCAIAGENHNGELTELFPVI
RKIGIQYENKLLNATQQINTQRGILFSSALLAAVAGWLSAQKQPLTYCALSQNISTLCQNLCRNDFAQLNQRAAKTQGEK
LYSEFGITGIRGEAEHGFPLVCNIALPALHQALAHQLSWRESLIHTLLALMACCEDTTVLSRGGQKALREMQSRAQRLVD
QGGMLQPDIGKKLTDFNQWCVDNWISPGGCADLLALTLAMYFLCQGDKHLIQENI

Specific function: Involved in the formation of 2-(5''-phosphoribosyl)-3'- dephosphocoenzyme-A, the prosthetic group of the acyl-carrier protein of the malonate decarboxylase [H]

COG id: COG1767

COG function: function code H; Triphosphoribosyl-dephospho-CoA synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CitG/MdcB family [H]

Homologues:

Organism=Escherichia coli, GI1786830, Length=272, Percent_Identity=38.2352941176471, Blast_Score=145, Evalue=3e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002736 [H]

Pfam domain/function: PF01874 CitG [H]

EC number: =2.7.8.25 [H]

Molecular weight: Translated: 32498; Mature: 32498

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
4.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYSTDSNAQWIGECLLKAILMEVCAWPKPGLVTPLSQGAHTDMDIWLFITSSSTIAPCFT
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHH
LCAIAGENHNGELTELFPVIRKIGIQYENKLLNATQQINTQRGILFSSALLAAVAGWLSA
HHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
QKQPLTYCALSQNISTLCQNLCRNDFAQLNQRAAKTQGEKLYSEFGITGIRGEAEHGFPL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCE
VCNIALPALHQALAHQLSWRESLIHTLLALMACCEDTTVLSRGGQKALREMQSRAQRLVD
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHH
QGGMLQPDIGKKLTDFNQWCVDNWISPGGCADLLALTLAMYFLCQGDKHLIQENI
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHCCC
>Mature Secondary Structure
MYSTDSNAQWIGECLLKAILMEVCAWPKPGLVTPLSQGAHTDMDIWLFITSSSTIAPCFT
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHH
LCAIAGENHNGELTELFPVIRKIGIQYENKLLNATQQINTQRGILFSSALLAAVAGWLSA
HHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
QKQPLTYCALSQNISTLCQNLCRNDFAQLNQRAAKTQGEKLYSEFGITGIRGEAEHGFPL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCE
VCNIALPALHQALAHQLSWRESLIHTLLALMACCEDTTVLSRGGQKALREMQSRAQRLVD
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHH
QGGMLQPDIGKKLTDFNQWCVDNWISPGGCADLLALTLAMYFLCQGDKHLIQENI
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9128730 [H]