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The map label for this gene is ttuB [H]

Identifier: 218550376

GI number: 218550376

Start: 3142850

End: 3144226

Strand: Direct

Name: ttuB [H]

Synonym: EFER_3068

Alternate gene names: 218550376

Gene position: 3142850-3144226 (Clockwise)

Preceding gene: 218550375

Following gene: 218550377

Centisome position: 68.49

GC content: 54.18

Gene sequence:

>1377_bases
ATGAGCGACACCTCACCTGCCATACCGGAAAGTATCGATCCGGCGAATCAGCATAAAGCGCTGACTGCCGGACAACAGGC
GGTTATTAAGAAGTTGTTTCGCCGCCTAATCATCTTTCTGTTCGTGCTGTTTATCTTCTCGTTCCTTGATCGCATCAACA
TCGGCTTTGCCGGACTGACGATGGGGCGCGACCTCGGTCTGAGCGCCACCATGTTTGGCCTCGCCACCACCCTGTTCTAC
GCCGCTTACGTCATCTTCGGCATTCCCAGCAACATTATGCTGAGTATTGTCGGTGCGCGACGCTGGATCGCCACCATAAT
GGTGCTTTGGGGCATCGCCTCTACTGCCACCATGTTTGCCACTGGCCCCACCAGCTTATACGTACTGCGTATACTGGTTG
GCATTACCGAAGCCGGTTTCCTGCCTGGCATTCTGCTGTATTTAACCTTCTGGTTTCCGGCCTACTTCCGCGCCCGTGCC
AACGCCTTGTTTATGGTGGCAATGCCGGTAACGACAGCGTTGGGATCTATCGTTTCCGGCTACATTTTGTCGCTGGATGG
CGTATTGGCACTAAAAGGCTGGCAGTGGCTGTTTTTGCTGGAAGGCTTCCCGTCGGTATTACTCGGCGTCATGGTGTGGT
TCTGGCTTGATGACTCACCGGATAAAGCTAAGTGGCTGACGAAAGAAGACAAAAAATGCCTGCAAGAGATGATGGATAAC
GATCGTCTGACGCTGGTGCAGCCAGAGGGAGCCATCAGCCACCACGCCATGCAACAACGCAGCATGTGGCGGGAGATCTT
CACTCCGGTGGTGATGATGTATACCCTGGCGTATTTCTGCCTGACCAACACACTTAGTGCGATCAGCATCTGGACACCGC
AGATCCTGCAAAGCTTTAATCAGGGCAGCAGTAATATCACCATCGGTCTGCTGGCGGCCGTACCGCAGATTTGTACCATT
CTCGGGATGATCTACTGGAGCCGTCACTCAGATCGCTGCCAGGAACGAAGGCACCACACCGCCCTTCCTTATTTGTTCGC
GGCCGCAGGTTGGTTACTGGCTTCGGCAACTGATCACAATATGATCCAGATGCTGGGGATCATTATGGCTTCGACCGGAT
CATTCAGCGCAATGGCAATTTTCTGGACAACACCGGATCAGTCCATCAGCCTGCGGGCACGCGCGATCGGTATTGCGGTG
ATCAACGCTACTGGCAATATCGGTTCGGCTCTGAGTCCGTTTATGATCGGCTGGCTGAAAGATCTGACCGGCAGCTTTAA
CAGTGGATTGTGGTTTGTTGCCGCGCTGCTGGTGATTGGTGCGGGGATTATCTGGGCGATTCCAATGCAGTCCTCCCGTC
CGCGAGCGACCCCATAA

Upstream 100 bases:

>100_bases
AGCCTACACGCGCACCAAACCGTAGGCCGGATAAGGCGTTTGTGCTGCATCTGCCATAAACCTTGTCGTACCCTACAAAA
ATCCCATTAGAGGAAGAAAA

Downstream 100 bases:

>100_bases
GGAACGACGATGTGCGATAGTCAGATTGCCAATATTGATATCAGCAAAGAGTATGATGAAAGCCTGGGCACGGACGATGT
GCATTATCAGTCGTTCGCCC

Product: 4-hydroxyphenylacetate permease hpaX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 458; Mature: 457

Protein sequence:

>458_residues
MSDTSPAIPESIDPANQHKALTAGQQAVIKKLFRRLIIFLFVLFIFSFLDRINIGFAGLTMGRDLGLSATMFGLATTLFY
AAYVIFGIPSNIMLSIVGARRWIATIMVLWGIASTATMFATGPTSLYVLRILVGITEAGFLPGILLYLTFWFPAYFRARA
NALFMVAMPVTTALGSIVSGYILSLDGVLALKGWQWLFLLEGFPSVLLGVMVWFWLDDSPDKAKWLTKEDKKCLQEMMDN
DRLTLVQPEGAISHHAMQQRSMWREIFTPVVMMYTLAYFCLTNTLSAISIWTPQILQSFNQGSSNITIGLLAAVPQICTI
LGMIYWSRHSDRCQERRHHTALPYLFAAAGWLLASATDHNMIQMLGIIMASTGSFSAMAIFWTTPDQSISLRARAIGIAV
INATGNIGSALSPFMIGWLKDLTGSFNSGLWFVAALLVIGAGIIWAIPMQSSRPRATP

Sequences:

>Translated_458_residues
MSDTSPAIPESIDPANQHKALTAGQQAVIKKLFRRLIIFLFVLFIFSFLDRINIGFAGLTMGRDLGLSATMFGLATTLFY
AAYVIFGIPSNIMLSIVGARRWIATIMVLWGIASTATMFATGPTSLYVLRILVGITEAGFLPGILLYLTFWFPAYFRARA
NALFMVAMPVTTALGSIVSGYILSLDGVLALKGWQWLFLLEGFPSVLLGVMVWFWLDDSPDKAKWLTKEDKKCLQEMMDN
DRLTLVQPEGAISHHAMQQRSMWREIFTPVVMMYTLAYFCLTNTLSAISIWTPQILQSFNQGSSNITIGLLAAVPQICTI
LGMIYWSRHSDRCQERRHHTALPYLFAAAGWLLASATDHNMIQMLGIIMASTGSFSAMAIFWTTPDQSISLRARAIGIAV
INATGNIGSALSPFMIGWLKDLTGSFNSGLWFVAALLVIGAGIIWAIPMQSSRPRATP
>Mature_457_residues
SDTSPAIPESIDPANQHKALTAGQQAVIKKLFRRLIIFLFVLFIFSFLDRINIGFAGLTMGRDLGLSATMFGLATTLFYA
AYVIFGIPSNIMLSIVGARRWIATIMVLWGIASTATMFATGPTSLYVLRILVGITEAGFLPGILLYLTFWFPAYFRARAN
ALFMVAMPVTTALGSIVSGYILSLDGVLALKGWQWLFLLEGFPSVLLGVMVWFWLDDSPDKAKWLTKEDKKCLQEMMDND
RLTLVQPEGAISHHAMQQRSMWREIFTPVVMMYTLAYFCLTNTLSAISIWTPQILQSFNQGSSNITIGLLAAVPQICTIL
GMIYWSRHSDRCQERRHHTALPYLFAAAGWLLASATDHNMIQMLGIIMASTGSFSAMAIFWTTPDQSISLRARAIGIAVI
NATGNIGSALSPFMIGWLKDLTGSFNSGLWFVAALLVIGAGIIWAIPMQSSRPRATP

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Escherichia coli, GI87082071, Length=431, Percent_Identity=31.322505800464, Blast_Score=216, Evalue=3e-57,
Organism=Escherichia coli, GI1789515, Length=424, Percent_Identity=24.0566037735849, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI87082320, Length=414, Percent_Identity=22.9468599033816, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1789152, Length=449, Percent_Identity=23.3853006681514, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI2367379, Length=422, Percent_Identity=23.696682464455, Blast_Score=70, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6322025, Length=419, Percent_Identity=25.7756563245823, Blast_Score=97, Evalue=5e-21,
Organism=Saccharomyces cerevisiae, GI6321698, Length=390, Percent_Identity=21.7948717948718, Blast_Score=79, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6324410, Length=143, Percent_Identity=26.5734265734266, Blast_Score=68, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6322612, Length=238, Percent_Identity=23.109243697479, Blast_Score=66, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 50526; Mature: 50395

Theoretical pI: Translated: 9.50; Mature: 9.50

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDTSPAIPESIDPANQHKALTAGQQAVIKKLFRRLIIFLFVLFIFSFLDRINIGFAGLT
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
MGRDLGLSATMFGLATTLFYAAYVIFGIPSNIMLSIVGARRWIATIMVLWGIASTATMFA
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
TGPTSLYVLRILVGITEAGFLPGILLYLTFWFPAYFRARANALFMVAMPVTTALGSIVSG
CCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHH
YILSLDGVLALKGWQWLFLLEGFPSVLLGVMVWFWLDDSPDKAKWLTKEDKKCLQEMMDN
HHHHHCCEEEECCCHHHHHHHCHHHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHCC
DRLTLVQPEGAISHHAMQQRSMWREIFTPVVMMYTLAYFCLTNTLSAISIWTPQILQSFN
CCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHC
QGSSNITIGLLAAVPQICTILGMIYWSRHSDRCQERRHHTALPYLFAAAGWLLASATDHN
CCCCCEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHH
MIQMLGIIMASTGSFSAMAIFWTTPDQSISLRARAIGIAVINATGNIGSALSPFMIGWLK
HHHHHHHHHHCCCCCEEEEEEEECCCCCCEEEEEEEEEEEEECCCCCCCHHHHHHHHHHH
DLTGSFNSGLWFVAALLVIGAGIIWAIPMQSSRPRATP
HHCCCCCCCHHHHHHHHHHCCCHHEEECCCCCCCCCCC
>Mature Secondary Structure 
SDTSPAIPESIDPANQHKALTAGQQAVIKKLFRRLIIFLFVLFIFSFLDRINIGFAGLT
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
MGRDLGLSATMFGLATTLFYAAYVIFGIPSNIMLSIVGARRWIATIMVLWGIASTATMFA
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
TGPTSLYVLRILVGITEAGFLPGILLYLTFWFPAYFRARANALFMVAMPVTTALGSIVSG
CCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHH
YILSLDGVLALKGWQWLFLLEGFPSVLLGVMVWFWLDDSPDKAKWLTKEDKKCLQEMMDN
HHHHHCCEEEECCCHHHHHHHCHHHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHCC
DRLTLVQPEGAISHHAMQQRSMWREIFTPVVMMYTLAYFCLTNTLSAISIWTPQILQSFN
CCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHC
QGSSNITIGLLAAVPQICTILGMIYWSRHSDRCQERRHHTALPYLFAAAGWLLASATDHN
CCCCCEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHH
MIQMLGIIMASTGSFSAMAIFWTTPDQSISLRARAIGIAVINATGNIGSALSPFMIGWLK
HHHHHHHHHHCCCCCEEEEEEEECCCCCCEEEEEEEEEEEEECCCCCCCHHHHHHHHHHH
DLTGSFNSGLWFVAALLVIGAGIIWAIPMQSSRPRATP
HHCCCCCCCHHHHHHHHHHCCCHHEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]