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The map label for this gene is yflS [H]

Identifier: 218550261

GI number: 218550261

Start: 3019211

End: 3020665

Strand: Direct

Name: yflS [H]

Synonym: EFER_2953

Alternate gene names: 218550261

Gene position: 3019211-3020665 (Clockwise)

Preceding gene: 218550260

Following gene: 218550262

Centisome position: 65.8

GC content: 50.24

Gene sequence:

>1455_bases
GTGGCGGAAAAAAATCCTCAGGGCGTCAAATGGCTCCCATTAATTATTATTGTTCTTATTTCTGGAGGATTGTGGCAAAT
TTCCCCGCCTTCCGGCCTTAGCGCACCGGCCTGGCATTCCGCCATTATTTTTGTCGCAACCATTGCATCGATTGTGGCAA
AAGTTCTCCCCATCGGCGCTGTAGGCATTATCGGTATTACCGTCTTTGCTCTTGCCTATGCTGCAGGCGATACCACTCCC
AGCAAAGCTATTGCTACCGCTCTGAGCGAATTAAACAGTTCGCTTATCTGGCTGATTGTCGTGGCATTTATGATTGCCAG
AGGCTTTATTAAAACCGGATTAGGGCGGCGTATCGCGTTACAAATGATCCGTTTGTTAGGCAAACGAACGCTGGGGCTGG
CGTATGGTCTGGCATTTGCCGACCTGATTCTCTCCCCTGCTATGCCCAGCAATACTGCACGCTGTGGTGGTGTCATTTAC
CCTATTGCCGATTCGCTGGCTCGCAGCTTCGACTCACGCCCGGATGATGAATCGCGCAGTAAAATTGGCACCTTCCTGGT
CACCTGTATTGGTAACGTCAACGATGTCACCGCGGCGCTGTTTATGACTGGTTACACTGGCAACCTGTTGGCGGTAAAAC
TGGCAGCAAATGCCGGAGTAACGTTAACCTGGGGAAGCTGGTTTATGGCGGCGCTACTGCCATGTGTGGTTTCGTTGTTG
ATCGTCCCGCTTTTGGTTTACTGGCTGACGCGCCCTGAGATAAAACATACCCCAGATGCTCCTGATATCGCTCGTAAAGA
GTTGGCGCAAATGGGTGAGATGTCGCGTGGTGAGTGGCTGATGCTGGCAACGGTTGGCGTCCTGCTGGTGTTGTGGATTT
TTGGCGATGTACTGAAAGTTGATGCCACTACCGCGTCGTTTGTTGGCCTGTCAATTTTACTACTGAGTGGCGTTCTCAGT
TGGGAAGATGTCAAAAGCGAAAAAGGCGCATGGGATACTTTAATCTGGTTTGCCGCGCTGTTGATGATGGCCAACCAATT
GAAAAAACTCGGTTTCACCACCTGGTTTGGTAACCTGATAGGTGACACAATTGGCAGTGCAATGGGGGGCACCAGTTGGG
TCGTGATTTTATTACTACTCAATGCGGCATATTTCTATACCCATTATTTCTTCGCCAGTGGTAACGCGCAGATTGCCGCA
CTGTATGCAGTCTTCCTCGGTGTAGGGCTACATCTTAATATTCCGGCGGCCCCCATGGCACTGATGCTGGCATTTACCAG
CAGCCTTTATTGCTCATTGACGCAATACACCCATGCCCGGGGTCCGATTCTGTTTGGTGCAGGGTATGTGCCAACAGGTG
TATGGTGGCGTACCGGCTTTGTTATTAGTTTATTTAACCAGGCGGTGTTTATTACGGTCGGCCTGGCCTGGTGGAAAATG
TTAGGTTTGTATTAA

Upstream 100 bases:

>100_bases
TTCCGAACACACGTGCAGCATTACCGGCAAATAACCAGATAATTACTCACGGTTATTATATTTAATGAATTTATATTCAT
ATTAATTATAGGTACTGACT

Downstream 100 bases:

>100_bases
GTCTATTTATGGCAAATTAAACCGTTTTTTCTATCTGTGGAGAAAACGGTTTTAAACCGTATTTAATACCGCAATAAATA
GATTCATCAAAAAAATGGAT

Product: sodium:sulfate symporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 484; Mature: 483

Protein sequence:

>484_residues
MAEKNPQGVKWLPLIIIVLISGGLWQISPPSGLSAPAWHSAIIFVATIASIVAKVLPIGAVGIIGITVFALAYAAGDTTP
SKAIATALSELNSSLIWLIVVAFMIARGFIKTGLGRRIALQMIRLLGKRTLGLAYGLAFADLILSPAMPSNTARCGGVIY
PIADSLARSFDSRPDDESRSKIGTFLVTCIGNVNDVTAALFMTGYTGNLLAVKLAANAGVTLTWGSWFMAALLPCVVSLL
IVPLLVYWLTRPEIKHTPDAPDIARKELAQMGEMSRGEWLMLATVGVLLVLWIFGDVLKVDATTASFVGLSILLLSGVLS
WEDVKSEKGAWDTLIWFAALLMMANQLKKLGFTTWFGNLIGDTIGSAMGGTSWVVILLLLNAAYFYTHYFFASGNAQIAA
LYAVFLGVGLHLNIPAAPMALMLAFTSSLYCSLTQYTHARGPILFGAGYVPTGVWWRTGFVISLFNQAVFITVGLAWWKM
LGLY

Sequences:

>Translated_484_residues
MAEKNPQGVKWLPLIIIVLISGGLWQISPPSGLSAPAWHSAIIFVATIASIVAKVLPIGAVGIIGITVFALAYAAGDTTP
SKAIATALSELNSSLIWLIVVAFMIARGFIKTGLGRRIALQMIRLLGKRTLGLAYGLAFADLILSPAMPSNTARCGGVIY
PIADSLARSFDSRPDDESRSKIGTFLVTCIGNVNDVTAALFMTGYTGNLLAVKLAANAGVTLTWGSWFMAALLPCVVSLL
IVPLLVYWLTRPEIKHTPDAPDIARKELAQMGEMSRGEWLMLATVGVLLVLWIFGDVLKVDATTASFVGLSILLLSGVLS
WEDVKSEKGAWDTLIWFAALLMMANQLKKLGFTTWFGNLIGDTIGSAMGGTSWVVILLLLNAAYFYTHYFFASGNAQIAA
LYAVFLGVGLHLNIPAAPMALMLAFTSSLYCSLTQYTHARGPILFGAGYVPTGVWWRTGFVISLFNQAVFITVGLAWWKM
LGLY
>Mature_483_residues
AEKNPQGVKWLPLIIIVLISGGLWQISPPSGLSAPAWHSAIIFVATIASIVAKVLPIGAVGIIGITVFALAYAAGDTTPS
KAIATALSELNSSLIWLIVVAFMIARGFIKTGLGRRIALQMIRLLGKRTLGLAYGLAFADLILSPAMPSNTARCGGVIYP
IADSLARSFDSRPDDESRSKIGTFLVTCIGNVNDVTAALFMTGYTGNLLAVKLAANAGVTLTWGSWFMAALLPCVVSLLI
VPLLVYWLTRPEIKHTPDAPDIARKELAQMGEMSRGEWLMLATVGVLLVLWIFGDVLKVDATTASFVGLSILLLSGVLSW
EDVKSEKGAWDTLIWFAALLMMANQLKKLGFTTWFGNLIGDTIGSAMGGTSWVVILLLLNAAYFYTHYFFASGNAQIAAL
YAVFLGVGLHLNIPAAPMALMLAFTSSLYCSLTQYTHARGPILFGAGYVPTGVWWRTGFVISLFNQAVFITVGLAWWKML
GLY

Specific function: Might be a malate transporter [H]

COG id: COG0471

COG function: function code P; Di- and tricarboxylate transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SLC13A transporter (TC 2.A.47) family [H]

Homologues:

Organism=Escherichia coli, GI1786986, Length=458, Percent_Identity=36.8995633187773, Blast_Score=271, Evalue=9e-74,
Organism=Escherichia coli, GI1786829, Length=482, Percent_Identity=32.1576763485477, Blast_Score=256, Evalue=3e-69,
Organism=Escherichia coli, GI1789444, Length=479, Percent_Identity=34.6555323590814, Blast_Score=251, Evalue=6e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001898 [H]

Pfam domain/function: PF00939 Na_sulph_symp [H]

EC number: NA

Molecular weight: Translated: 51977; Mature: 51846

Theoretical pI: Translated: 9.37; Mature: 9.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEKNPQGVKWLPLIIIVLISGGLWQISPPSGLSAPAWHSAIIFVATIASIVAKVLPIGA
CCCCCCCCCHHHHHHHHHHHCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCH
VGIIGITVFALAYAAGDTTPSKAIATALSELNSSLIWLIVVAFMIARGFIKTGLGRRIAL
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHH
QMIRLLGKRTLGLAYGLAFADLILSPAMPSNTARCGGVIYPIADSLARSFDSRPDDESRS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEHHHHHHHHHHHCCCCCHHHHH
KIGTFLVTCIGNVNDVTAALFMTGYTGNLLAVKLAANAGVTLTWGSWFMAALLPCVVSLL
HHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEEEECCCCEEEEEHHHHHHHHHHHHHHHH
IVPLLVYWLTRPEIKHTPDAPDIARKELAQMGEMSRGEWLMLATVGVLLVLWIFGDVLKV
HHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
DATTASFVGLSILLLSGVLSWEDVKSEKGAWDTLIWFAALLMMANQLKKLGFTTWFGNLI
CCHHHHHHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
GDTIGSAMGGTSWVVILLLLNAAYFYTHYFFASGNAQIAALYAVFLGVGLHLNIPAAPMA
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHCCCEECCCHHHHH
LMLAFTSSLYCSLTQYTHARGPILFGAGYVPTGVWWRTGFVISLFNQAVFITVGLAWWKM
HHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHH
LGLY
HCCC
>Mature Secondary Structure 
AEKNPQGVKWLPLIIIVLISGGLWQISPPSGLSAPAWHSAIIFVATIASIVAKVLPIGA
CCCCCCCCHHHHHHHHHHHCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCH
VGIIGITVFALAYAAGDTTPSKAIATALSELNSSLIWLIVVAFMIARGFIKTGLGRRIAL
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHH
QMIRLLGKRTLGLAYGLAFADLILSPAMPSNTARCGGVIYPIADSLARSFDSRPDDESRS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEHHHHHHHHHHHCCCCCHHHHH
KIGTFLVTCIGNVNDVTAALFMTGYTGNLLAVKLAANAGVTLTWGSWFMAALLPCVVSLL
HHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEEEECCCCEEEEEHHHHHHHHHHHHHHHH
IVPLLVYWLTRPEIKHTPDAPDIARKELAQMGEMSRGEWLMLATVGVLLVLWIFGDVLKV
HHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
DATTASFVGLSILLLSGVLSWEDVKSEKGAWDTLIWFAALLMMANQLKKLGFTTWFGNLI
CCHHHHHHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
GDTIGSAMGGTSWVVILLLLNAAYFYTHYFFASGNAQIAALYAVFLGVGLHLNIPAAPMA
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHCCCEECCCHHHHH
LMLAFTSSLYCSLTQYTHARGPILFGAGYVPTGVWWRTGFVISLFNQAVFITVGLAWWKM
HHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHH
LGLY
HCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9272861; 9384377; 12949159 [H]