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The map label for this gene is yghZ [H]

Identifier: 218550251

GI number: 218550251

Start: 3009711

End: 3010751

Strand: Direct

Name: yghZ [H]

Synonym: EFER_2943

Alternate gene names: 218550251

Gene position: 3009711-3010751 (Clockwise)

Preceding gene: 218550240

Following gene: 218550253

Centisome position: 65.59

GC content: 51.1

Gene sequence:

>1041_bases
ATGGTCTGGTTAGCGAATCCCGAACGTTACGGGCAGATGCAGTACCGCTATTGCGGAAAAAGCGGTTTACGCCTGCCCGC
GTTATCGCTCGGTTTATGGCACAATTTCGGTCACGTTAACGCGCTGGAATCACAGCGCGTGATTCTGCGAAAAGCTTTTG
ATTTAGGCATTACACACTTTGATTTAGCCAACAACTACGGGCCTCCTCCAGGAAGCGCAGAAGAGAACTTTGGTCGCCTG
CTGCGCGAGGATTTTGCTGCTTATCGCGATGAACTGATTATCTCTACCAAAGCTGGCTACGATATGTGGCCCGGCCCGTA
CGGCTCTGGCGGCTCACGTAAATACCTGCTCGCCAGCCTCGACCAAAGCCTGAAGCGTATGGGGCTGGAGTATGTCGATA
TCTTTTACTCTCATCGCGTCGATGAAAATACGCCGATGGAAGAAACCGCCTCTGCGCTGGCTCATGCGGTACAAAGCGGT
AAAGCGCTTTATGTCGGGATCTCCTCTTACTCGCCAGAGCGGACGCAAAAAATGGTCGAATTACTGCGTGAGTGGAAAAT
TCCGCTGTTAATTCATCAACCTTCATACAATTTACTTAACCGCTGGGTAGATAAAAGTGGCCTGCTGGATACCCTGGAAA
ATAACGGCGTGGGCTGCATTGCCTTTACTCCTCTGGCTCAGGGATTGCTGACCGGCAAATATCTCAACGGTATTCCTGAA
GATTCACGGATGCATCGTGAAGGGAATAAAGTTCGTGGCCTGACACCGAAAATGCTCACCGAAGCCAACCTCAACAGCCT
GCAGTTATTAAATGAAATGGCACAGCAGCGCGGTCAGTCGATGGCGCAAATGGCGTTAAGCTGGTTGCTGAAAGATGAGC
GAGTGACGTCGGTATTGATTGGTGCCAGCCGTGCGGAGCAACTGGAAGAGAACGTGGAGGCGCTAAATAATCTGACGTTT
AGCACTGAGGAGTTAGCGCAGATTGACCAGCATATAGCCGATGGCGAGCTGAATCTGTGGCAGGCATCGTCCGATAAATG
A

Upstream 100 bases:

>100_bases
CAGTTTTTCGTCACACTGTGAGCGATGCTACGGGATATCCCCTGGTAAATCGCTAGACTGGAAACATTGTTTCGAAATTG
AACGGTGGAAAGGAGAGGTC

Downstream 100 bases:

>100_bases
CGTATTGATAACGGGCGCGAGAACCGCGCCCGAATCAGATCAGTGATTATGACGAGTCAGTCGGTCAAGATAGCCCATCA
CAAATGCAGAGAGCACAAAC

Product: aldo-keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MVWLANPERYGQMQYRYCGKSGLRLPALSLGLWHNFGHVNALESQRVILRKAFDLGITHFDLANNYGPPPGSAEENFGRL
LREDFAAYRDELIISTKAGYDMWPGPYGSGGSRKYLLASLDQSLKRMGLEYVDIFYSHRVDENTPMEETASALAHAVQSG
KALYVGISSYSPERTQKMVELLREWKIPLLIHQPSYNLLNRWVDKSGLLDTLENNGVGCIAFTPLAQGLLTGKYLNGIPE
DSRMHREGNKVRGLTPKMLTEANLNSLQLLNEMAQQRGQSMAQMALSWLLKDERVTSVLIGASRAEQLEENVEALNNLTF
STEELAQIDQHIADGELNLWQASSDK

Sequences:

>Translated_346_residues
MVWLANPERYGQMQYRYCGKSGLRLPALSLGLWHNFGHVNALESQRVILRKAFDLGITHFDLANNYGPPPGSAEENFGRL
LREDFAAYRDELIISTKAGYDMWPGPYGSGGSRKYLLASLDQSLKRMGLEYVDIFYSHRVDENTPMEETASALAHAVQSG
KALYVGISSYSPERTQKMVELLREWKIPLLIHQPSYNLLNRWVDKSGLLDTLENNGVGCIAFTPLAQGLLTGKYLNGIPE
DSRMHREGNKVRGLTPKMLTEANLNSLQLLNEMAQQRGQSMAQMALSWLLKDERVTSVLIGASRAEQLEENVEALNNLTF
STEELAQIDQHIADGELNLWQASSDK
>Mature_346_residues
MVWLANPERYGQMQYRYCGKSGLRLPALSLGLWHNFGHVNALESQRVILRKAFDLGITHFDLANNYGPPPGSAEENFGRL
LREDFAAYRDELIISTKAGYDMWPGPYGSGGSRKYLLASLDQSLKRMGLEYVDIFYSHRVDENTPMEETASALAHAVQSG
KALYVGISSYSPERTQKMVELLREWKIPLLIHQPSYNLLNRWVDKSGLLDTLENNGVGCIAFTPLAQGLLTGKYLNGIPE
DSRMHREGNKVRGLTPKMLTEANLNSLQLLNEMAQQRGQSMAQMALSWLLKDERVTSVLIGASRAEQLEENVEALNNLTF
STEELAQIDQHIADGELNLWQASSDK

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI4504825, Length=338, Percent_Identity=35.7988165680473, Blast_Score=181, Evalue=1e-45,
Organism=Homo sapiens, GI27436969, Length=329, Percent_Identity=35.5623100303951, Blast_Score=181, Evalue=1e-45,
Organism=Homo sapiens, GI27436964, Length=324, Percent_Identity=35.1851851851852, Blast_Score=177, Evalue=1e-44,
Organism=Homo sapiens, GI27436962, Length=324, Percent_Identity=35.1851851851852, Blast_Score=176, Evalue=2e-44,
Organism=Homo sapiens, GI27436966, Length=324, Percent_Identity=34.8765432098765, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI27436971, Length=326, Percent_Identity=34.0490797546012, Blast_Score=162, Evalue=6e-40,
Organism=Homo sapiens, GI41152114, Length=212, Percent_Identity=31.6037735849057, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI41327764, Length=214, Percent_Identity=30.3738317757009, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI223718702, Length=214, Percent_Identity=29.9065420560748, Blast_Score=78, Evalue=2e-14,
Organism=Escherichia coli, GI1789375, Length=346, Percent_Identity=97.9768786127168, Blast_Score=704, Evalue=0.0,
Organism=Escherichia coli, GI87081735, Length=330, Percent_Identity=36.0606060606061, Blast_Score=156, Evalue=2e-39,
Organism=Escherichia coli, GI1789199, Length=350, Percent_Identity=28.5714285714286, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1788070, Length=318, Percent_Identity=26.7295597484277, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1788081, Length=323, Percent_Identity=23.5294117647059, Blast_Score=71, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6325169, Length=337, Percent_Identity=22.8486646884273, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6323998, Length=315, Percent_Identity=25.3968253968254, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6319958, Length=238, Percent_Identity=25.6302521008403, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6322615, Length=238, Percent_Identity=25.2100840336134, Blast_Score=71, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24640980, Length=339, Percent_Identity=27.7286135693215, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI45549126, Length=339, Percent_Identity=27.7286135693215, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24646159, Length=334, Percent_Identity=24.5508982035928, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24646155, Length=328, Percent_Identity=25.609756097561, Blast_Score=72, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR005399
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 38851; Mature: 38851

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVWLANPERYGQMQYRYCGKSGLRLPALSLGLWHNFGHVNALESQRVILRKAFDLGITHF
CEECCCHHHHCCHHHHHHCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEE
DLANNYGPPPGSAEENFGRLLREDFAAYRDELIISTKAGYDMWPGPYGSGGSRKYLLASL
EHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCHHHHHHH
DQSLKRMGLEYVDIFYSHRVDENTPMEETASALAHAVQSGKALYVGISSYSPERTQKMVE
HHHHHHHCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHH
LLREWKIPLLIHQPSYNLLNRWVDKSGLLDTLENNGVGCIAFTPLAQGLLTGKYLNGIPE
HHHHCCCCEEEECCCHHHHHHHHHHCCCHHHHHCCCEEEEEEHHHHHHHHHHHHHCCCCC
DSRMHREGNKVRGLTPKMLTEANLNSLQLLNEMAQQRGQSMAQMALSWLLKDERVTSVLI
HHHHHHCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GASRAEQLEENVEALNNLTFSTEELAQIDQHIADGELNLWQASSDK
CCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEECCCCCC
>Mature Secondary Structure
MVWLANPERYGQMQYRYCGKSGLRLPALSLGLWHNFGHVNALESQRVILRKAFDLGITHF
CEECCCHHHHCCHHHHHHCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEE
DLANNYGPPPGSAEENFGRLLREDFAAYRDELIISTKAGYDMWPGPYGSGGSRKYLLASL
EHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCHHHHHHH
DQSLKRMGLEYVDIFYSHRVDENTPMEETASALAHAVQSGKALYVGISSYSPERTQKMVE
HHHHHHHCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHH
LLREWKIPLLIHQPSYNLLNRWVDKSGLLDTLENNGVGCIAFTPLAQGLLTGKYLNGIPE
HHHHCCCCEEEECCCHHHHHHHHHHCCCHHHHHCCCEEEEEEHHHHHHHHHHHHHCCCCC
DSRMHREGNKVRGLTPKMLTEANLNSLQLLNEMAQQRGQSMAQMALSWLLKDERVTSVLI
HHHHHHCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GASRAEQLEENVEALNNLTFSTEELAQIDQHIADGELNLWQASSDK
CCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]