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The map label for this gene is speC [H]

Identifier: 218550216

GI number: 218550216

Start: 2971457

End: 2973598

Strand: Reverse

Name: speC [H]

Synonym: EFER_2908

Alternate gene names: 218550216

Gene position: 2973598-2971457 (Counterclockwise)

Preceding gene: 218550234

Following gene: 218550214

Centisome position: 64.8

GC content: 49.3

Gene sequence:

>2142_bases
TTGAGCATGAAAACAATGAAAATTGCCGCCAGTGGTGAACTGGTTGCCCGTTTGTCTACGCATCGTGATGTGGTGGCGCT
GGATAGTACCGATTTTACCGAAGTCGCCGCTGTCGTCATCACGGTTACGGATAGTCGCAGTGGGATCCTTACCTTACTCA
AACGCACTGGTTTTCAATTACCCGTATTTCTCTTTAGCGAGCAGGCTTGCTCGATGCCGCAGGGGGTGACAGCGGTTATG
AACGGTAGCGAACAACAATGGCTGGAGTTGGAAGCTGCTGCCCGTCGCTATGAAGAAAATATGCTACCGCCGTTTTATGA
CACCTTGACTCAGTATGTCGCAATGAGGAATAGCACTTTTGCCTGCCCTGGGCATCAGCATGGCGCATTCTTTAAAAAGC
ATCCTGCTGGTCGTCATTTTTATGATTTCTTTGGCGAGAATGTTTTTCGCGCCGATATGTGTAATGCCGATGTCAGGTTG
GGCGATTTATTGATTCATGAAGGCTCAGCAAAAGATGCTCAAAAGTTTGCCGCCAAAGTTTTTCATGCCGATAAAACCTA
CTTTGTTCTGAATGGAACTTCGGCGGCAAATAAAGTGGTCACCAATGCATTACTGACACGTGGCGATCTGGTGCTTTTTG
ATCGCAATAATCATAAATCAAATCATCATGGTGCTCTGATTCAGGCTGGCGCAACACCGATTTATTTAGAAGCTGCGCGT
AATCCGTTTGGCTTTATTGGGGGTATTGATGCGCACTGTTTTAATGAAGAGTATCTGCGCCAGCAAATTCGTGCCGTTGC
GCCAGAAAAGGCTGACCAGCCGCGCCCATTCCGTCTGGCAATTATTCAGTTGGGAACTTACGACGGCACTATCTACAACG
CTCGTCAGGTGATCGACACCATCGGTCATCTTTGTGATTACATTTTGTTTGATTCTGCCTGGGTCGGTTATGAGCAGTTT
ATCCCGATGCTGGCAAATAGCTCGCCGTTGTTGTTAGAGCTTGACGAAAAAGATCCTGGCATTTTTGTCACTCAGTCGGT
ACACAAGCAGCAAGCCGGATTCTCGCAAACCTCCCAGATCCATAAAAAAGATAACCATATTCGCGGGCAGGCACGTTTTT
GTCCGCATAAACGGCTGAATAACGCATTTATGTTGCATGCTTCCACCAGCCCTTTTTATCCATTGTTTGCCGCGCTGGAT
GTTAACGCCAAAATCCACGAAGGGGAGAGTGGGCGTCGGTTGTGGGCTGATTGCGTGACTCTGGGGATCGAAACCCGTAA
GGCGATTCTGGAACGTTGTCATCTGCTGCACCCGTTTGTGCCGCCGGTTGTGGATGGTAAGCTGTGGCAAGCGTGGTCGA
CAGAAGTTATCGCCAGCGAGAGACGGTTTTTTAGTTTTGAACCTGGAGCAACCTGGCATGGATTTGAAGGTTATGCGGAG
GACCAATATGTTATCGACCCGTGTAAATTGCTGCTGACAACACCAGGAATCGATGCTGCCAGTGGTGAGTATAGCGATTT
TGGCGTTCCTGCGACCATTCTGGCGCATTACCTGCGTGAAAATGGCATAGTGCCTGAAAAGTGCGATCTCAATTCCATTT
TGTTCCTGCTGACGCCTGCCGAAAGTGCCGAGAAGATGGCACATTTGGTGGCAATGCTGGTGCAATTTGAACAACATATT
GAAGATGACACACCACTGGCTGATGTGCTGCCGTCTGTCTTCAACAAGTATCCGGTACGTTATCGTGACTATACCCTGCG
CCAGCTCTGTCAGGAGATGCACGATCTGTATGTCAGTTTCGACGTCAAAGACCTGCAAAAAGCGATGTTCCGCCAGCTGA
GTTTCCCGAAAGTAATGATGAACCCACAGGATGCGCATAGCGCCTATATTCGCGGTGAAGTGGAGTTGGTGCGGATTCGT
GATGCCGAAGGGCGAATTGCGGCCGAAGGGGCGTTACCTTATCCACCTGGCGTGCTGTGCGTGGTGCCTGGAGAAGAGTG
GGGCGGGGCGGTACAGCGTTATTTTCTGGCGCTGGAAGAAGGGGTGAATTTGCTACCAGGATTTTCGCCGGAGTTACAAG
GTGTCTATAGCGAAACAGATACGGACGGGATGAAACGTTTGTATGGTTATGTTTTGAAGTGA

Upstream 100 bases:

>100_bases
TTTTACTGATGTCTGGTGGTTGCAGCTGCGAACCAGTCTGGGCAACGACTCTTCGGGCAAGGCTAGCACCTTGCTCTGGT
GCTAACTTTTTCGAAATGAA

Downstream 100 bases:

>100_bases
GAATAAAAAACGGGGCACCTTCTGGCGCCCCGTTGCTGTTTCATCACTTATTAGTGGCTGGTAGTTTGCGTACCGGCAGG
TACACGAACATGTTTGTATT

Product: ornithine decarboxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 713; Mature: 712

Protein sequence:

>713_residues
MSMKTMKIAASGELVARLSTHRDVVALDSTDFTEVAAVVITVTDSRSGILTLLKRTGFQLPVFLFSEQACSMPQGVTAVM
NGSEQQWLELEAAARRYEENMLPPFYDTLTQYVAMRNSTFACPGHQHGAFFKKHPAGRHFYDFFGENVFRADMCNADVRL
GDLLIHEGSAKDAQKFAAKVFHADKTYFVLNGTSAANKVVTNALLTRGDLVLFDRNNHKSNHHGALIQAGATPIYLEAAR
NPFGFIGGIDAHCFNEEYLRQQIRAVAPEKADQPRPFRLAIIQLGTYDGTIYNARQVIDTIGHLCDYILFDSAWVGYEQF
IPMLANSSPLLLELDEKDPGIFVTQSVHKQQAGFSQTSQIHKKDNHIRGQARFCPHKRLNNAFMLHASTSPFYPLFAALD
VNAKIHEGESGRRLWADCVTLGIETRKAILERCHLLHPFVPPVVDGKLWQAWSTEVIASERRFFSFEPGATWHGFEGYAE
DQYVIDPCKLLLTTPGIDAASGEYSDFGVPATILAHYLRENGIVPEKCDLNSILFLLTPAESAEKMAHLVAMLVQFEQHI
EDDTPLADVLPSVFNKYPVRYRDYTLRQLCQEMHDLYVSFDVKDLQKAMFRQLSFPKVMMNPQDAHSAYIRGEVELVRIR
DAEGRIAAEGALPYPPGVLCVVPGEEWGGAVQRYFLALEEGVNLLPGFSPELQGVYSETDTDGMKRLYGYVLK

Sequences:

>Translated_713_residues
MSMKTMKIAASGELVARLSTHRDVVALDSTDFTEVAAVVITVTDSRSGILTLLKRTGFQLPVFLFSEQACSMPQGVTAVM
NGSEQQWLELEAAARRYEENMLPPFYDTLTQYVAMRNSTFACPGHQHGAFFKKHPAGRHFYDFFGENVFRADMCNADVRL
GDLLIHEGSAKDAQKFAAKVFHADKTYFVLNGTSAANKVVTNALLTRGDLVLFDRNNHKSNHHGALIQAGATPIYLEAAR
NPFGFIGGIDAHCFNEEYLRQQIRAVAPEKADQPRPFRLAIIQLGTYDGTIYNARQVIDTIGHLCDYILFDSAWVGYEQF
IPMLANSSPLLLELDEKDPGIFVTQSVHKQQAGFSQTSQIHKKDNHIRGQARFCPHKRLNNAFMLHASTSPFYPLFAALD
VNAKIHEGESGRRLWADCVTLGIETRKAILERCHLLHPFVPPVVDGKLWQAWSTEVIASERRFFSFEPGATWHGFEGYAE
DQYVIDPCKLLLTTPGIDAASGEYSDFGVPATILAHYLRENGIVPEKCDLNSILFLLTPAESAEKMAHLVAMLVQFEQHI
EDDTPLADVLPSVFNKYPVRYRDYTLRQLCQEMHDLYVSFDVKDLQKAMFRQLSFPKVMMNPQDAHSAYIRGEVELVRIR
DAEGRIAAEGALPYPPGVLCVVPGEEWGGAVQRYFLALEEGVNLLPGFSPELQGVYSETDTDGMKRLYGYVLK
>Mature_712_residues
SMKTMKIAASGELVARLSTHRDVVALDSTDFTEVAAVVITVTDSRSGILTLLKRTGFQLPVFLFSEQACSMPQGVTAVMN
GSEQQWLELEAAARRYEENMLPPFYDTLTQYVAMRNSTFACPGHQHGAFFKKHPAGRHFYDFFGENVFRADMCNADVRLG
DLLIHEGSAKDAQKFAAKVFHADKTYFVLNGTSAANKVVTNALLTRGDLVLFDRNNHKSNHHGALIQAGATPIYLEAARN
PFGFIGGIDAHCFNEEYLRQQIRAVAPEKADQPRPFRLAIIQLGTYDGTIYNARQVIDTIGHLCDYILFDSAWVGYEQFI
PMLANSSPLLLELDEKDPGIFVTQSVHKQQAGFSQTSQIHKKDNHIRGQARFCPHKRLNNAFMLHASTSPFYPLFAALDV
NAKIHEGESGRRLWADCVTLGIETRKAILERCHLLHPFVPPVVDGKLWQAWSTEVIASERRFFSFEPGATWHGFEGYAED
QYVIDPCKLLLTTPGIDAASGEYSDFGVPATILAHYLRENGIVPEKCDLNSILFLLTPAESAEKMAHLVAMLVQFEQHIE
DDTPLADVLPSVFNKYPVRYRDYTLRQLCQEMHDLYVSFDVKDLQKAMFRQLSFPKVMMNPQDAHSAYIRGEVELVRIRD
AEGRIAAEGALPYPPGVLCVVPGEEWGGAVQRYFLALEEGVNLLPGFSPELQGVYSETDTDGMKRLYGYVLK

Specific function: Spermidine biosynthesis from ornithine. [C]

COG id: COG1982

COG function: function code E; Arginine/lysine/ornithine decarboxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-I family [H]

Homologues:

Organism=Escherichia coli, GI87082193, Length=711, Percent_Identity=89.4514767932489, Blast_Score=1348, Evalue=0.0,
Organism=Escherichia coli, GI1786909, Length=719, Percent_Identity=65.9248956884562, Blast_Score=998, Evalue=0.0,
Organism=Escherichia coli, GI221142684, Length=642, Percent_Identity=32.398753894081, Blast_Score=347, Evalue=1e-96,
Organism=Escherichia coli, GI1790573, Length=615, Percent_Identity=33.8211382113821, Blast_Score=328, Evalue=7e-91,
Organism=Escherichia coli, GI1786384, Length=616, Percent_Identity=33.7662337662338, Blast_Score=321, Evalue=1e-88,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR005308
- InterPro:   IPR011193
- InterPro:   IPR000310
- InterPro:   IPR008286
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01276 OKR_DC_1; PF03711 OKR_DC_1_C; PF03709 OKR_DC_1_N [H]

EC number: =4.1.1.17 [H]

Molecular weight: Translated: 79893; Mature: 79762

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: PS00703 OKR_DC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMKTMKIAASGELVARLSTHRDVVALDSTDFTEVAAVVITVTDSRSGILTLLKRTGFQL
CCCCEEEEECCCCHHEEHHCCCCEEEECCCCHHEEEEEEEEEECCCCHHHHHHHHCCCCC
PVFLFSEQACSMPQGVTAVMNGSEQQWLELEAAARRYEENMLPPFYDTLTQYVAMRNSTF
EEEEECCHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEE
ACPGHQHGAFFKKHPAGRHFYDFFGENVFRADMCNADVRLGDLLIHEGSAKDAQKFAAKV
ECCCCCCCCCHHCCCCCCHHHHHHCCCEEEHHCCCCCCEEEEEEEECCCCHHHHHHHHHH
FHADKTYFVLNGTSAANKVVTNALLTRGDLVLFDRNNHKSNHHGALIQAGATPIYLEAAR
HCCCCEEEEEECCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEECCCCEEEEEECC
NPFGFIGGIDAHCFNEEYLRQQIRAVAPEKADQPRPFRLAIIQLGTYDGTIYNARQVIDT
CCCCEECCCCHHHCCHHHHHHHHHHHCCCCCCCCCCEEEEEEEEECCCCCCHHHHHHHHH
IGHLCDYILFDSAWVGYEQFIPMLANSSPLLLELDEKDPGIFVTQSVHKQQAGFSQTSQI
HHHHHHHHHHCCCCCCHHHHHHHHCCCCCEEEEECCCCCCEEEEHHHHHHHCCCHHHHHH
HKKDNHIRGQARFCPHKRLNNAFMLHASTSPFYPLFAALDVNAKIHEGESGRRLWADCVT
HHCCCCCCCCCCCCCHHHCCCEEEEEECCCCCCEEEEEEECCCEEECCCCCCHHHHHHHH
LGIETRKAILERCHLLHPFVPPVVDGKLWQAWSTEVIASERRFFSFEPGATWHGFEGYAE
HHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCC
DQYVIDPCKLLLTTPGIDAASGEYSDFGVPATILAHYLRENGIVPEKCDLNSILFLLTPA
CCEEECCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEEECC
ESAEKMAHLVAMLVQFEQHIEDDTPLADVLPSVFNKYPVRYRDYTLRQLCQEMHDLYVSF
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEECCHHHHHHHHHHHHHEEEC
DVKDLQKAMFRQLSFPKVMMNPQDAHSAYIRGEVELVRIRDAEGRIAAEGALPYPPGVLC
CHHHHHHHHHHHCCCCCEECCCCHHCCEEEECCEEEEEEECCCCCEEECCCCCCCCCEEE
VVPGEEWGGAVQRYFLALEEGVNLLPGFSPELQGVYSETDTDGMKRLYGYVLK
EECCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SMKTMKIAASGELVARLSTHRDVVALDSTDFTEVAAVVITVTDSRSGILTLLKRTGFQL
CCCEEEEECCCCHHEEHHCCCCEEEECCCCHHEEEEEEEEEECCCCHHHHHHHHCCCCC
PVFLFSEQACSMPQGVTAVMNGSEQQWLELEAAARRYEENMLPPFYDTLTQYVAMRNSTF
EEEEECCHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEE
ACPGHQHGAFFKKHPAGRHFYDFFGENVFRADMCNADVRLGDLLIHEGSAKDAQKFAAKV
ECCCCCCCCCHHCCCCCCHHHHHHCCCEEEHHCCCCCCEEEEEEEECCCCHHHHHHHHHH
FHADKTYFVLNGTSAANKVVTNALLTRGDLVLFDRNNHKSNHHGALIQAGATPIYLEAAR
HCCCCEEEEEECCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEECCCCEEEEEECC
NPFGFIGGIDAHCFNEEYLRQQIRAVAPEKADQPRPFRLAIIQLGTYDGTIYNARQVIDT
CCCCEECCCCHHHCCHHHHHHHHHHHCCCCCCCCCCEEEEEEEEECCCCCCHHHHHHHHH
IGHLCDYILFDSAWVGYEQFIPMLANSSPLLLELDEKDPGIFVTQSVHKQQAGFSQTSQI
HHHHHHHHHHCCCCCCHHHHHHHHCCCCCEEEEECCCCCCEEEEHHHHHHHCCCHHHHHH
HKKDNHIRGQARFCPHKRLNNAFMLHASTSPFYPLFAALDVNAKIHEGESGRRLWADCVT
HHCCCCCCCCCCCCCHHHCCCEEEEEECCCCCCEEEEEEECCCEEECCCCCCHHHHHHHH
LGIETRKAILERCHLLHPFVPPVVDGKLWQAWSTEVIASERRFFSFEPGATWHGFEGYAE
HHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCC
DQYVIDPCKLLLTTPGIDAASGEYSDFGVPATILAHYLRENGIVPEKCDLNSILFLLTPA
CCEEECCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEEECC
ESAEKMAHLVAMLVQFEQHIEDDTPLADVLPSVFNKYPVRYRDYTLRQLCQEMHDLYVSF
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEECCHHHHHHHHHHHHHEEEC
DVKDLQKAMFRQLSFPKVMMNPQDAHSAYIRGEVELVRIRDAEGRIAAEGALPYPPGVLC
CHHHHHHHHHHHCCCCCEECCCCHHCCEEEECCEEEEEEECCCCCEEECCCCCCCCCEEE
VVPGEEWGGAVQRYFLALEEGVNLLPGFSPELQGVYSETDTDGMKRLYGYVLK
EECCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]